Liver-directed gene therapy: A retroviral vector with a complete LTR and the ApoE enhancer-α1-antitrypsin promoter dramatically increases expression of human α1-antitrypsin in vivo

Human Gene Therapy

Volumn 7, Issue 5, 1996, Pages 637-645

  Okuyama, Torayuki ^a   Huber, Reid M ^a   Bowling, William ^a   Pearline, Rachel ^a   Kennedy, Susan C ^a   Flye, M Wayne ^a   Ponder, Katherine Parker ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Box 8231 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN E; COMPLEMENTARY DNA;

ANIMAL CELL; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; ENHANCER REGION; EXPRESSION VECTOR; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; LIVER; LIVER CELL; LIVER REGENERATION; LONG TERMINAL REPEAT; MOUSE; NONHUMAN; PROMOTER REGION; RECOMBINANT GENE; RETROVIRUS;

ALPHA 1-ANTITRYPSIN; ANIMALS; APOLIPOPROTEINS E; BLOTTING, NORTHERN; CELLS, CULTURED; DNA, VIRAL; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HUMANS; LIVER; MICE; PROMOTER REGIONS (GENETICS); RATS; REPETITIVE SEQUENCES, NUCLEIC ACID; RETROVIRIDAE; RNA, VIRAL; TRANSDUCTION, GENETIC;

EID: 0030008178     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.5-637     Document Type: Article

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