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Volumn 4, Issue 5, 1997, Pages 393-400

Persistent transgene expression in mouse liver following in vivo gene transfer with a ΔE1/ΔE4 adenovirus vector

Author keywords

Cytopathic effects; Immune response; Transgene expression; E1 E4 adenovirus vector

Indexed keywords

ADENOVIRUS; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; EXPRESSION VECTOR; GENE DELETION; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; LIVER; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; VIRUS GENE; VIRUS IMMUNITY;

EID: 0031008929     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300404     Document Type: Article
Times cited : (131)

References (32)
  • 1
    • 0028274169 scopus 로고
    • In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs
    • Kay MA et al. In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc Natl Acad Sci USA 1994; 91: 2353-2357.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2353-2357
    • Kay, M.A.1
  • 2
    • 0028418190 scopus 로고
    • Intraperitoneal in vivo gene therapy to deliver α-antitrypsin to the systemic circulation
    • Setoguchi Y, Jaffe HA, Chu C-S, Crystal RG. Intraperitoneal in vivo gene therapy to deliver α-antitrypsin to the systemic circulation. Am J Respir Cell Mol Biol 1994; 10: 369-377.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 369-377
    • Setoguchi, Y.1    Jaffe, H.A.2    Chu, C.-S.3    Crystal, R.G.4
  • 3
    • 0028234357 scopus 로고
    • In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
    • Kozarsky KF et al. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J Biol Chem 1994; 269: 13695-13702.
    • (1994) J Biol Chem , vol.269 , pp. 13695-13702
    • Kozarsky, K.F.1
  • 4
    • 0029127914 scopus 로고
    • Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero
    • Vincent MC et al. Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero. Hum Gene Ther 1995; 6: 1019-1028.
    • (1995) Hum Gene Ther , vol.6 , pp. 1019-1028
    • Vincent, M.C.1
  • 5
    • 0013793174 scopus 로고
    • Antigens and structure of the adenovirus
    • Valentine RC, Pereira HG. Antigens and structure of the adenovirus. J Mol Biol 1965; 13: 13-20.
    • (1965) J Mol Biol , vol.13 , pp. 13-20
    • Valentine, R.C.1    Pereira, H.G.2
  • 6
    • 0028934815 scopus 로고
    • Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
    • Dai Y et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci USA 1995; 92: 1401-1405.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1401-1405
    • Dai, Y.1
  • 7
    • 0028246338 scopus 로고
    • Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
    • Engelhardt JF, Ye X, Doranz B, Wilson JM. Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci USA 1994; 91: 6196-6200.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6196-6200
    • Engelhardt, J.F.1    Ye, X.2    Doranz, B.3    Wilson, J.M.4
  • 8
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
    • Yang Y et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 1994; 91: 4407-4411.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4407-4411
    • Yang, Y.1
  • 9
    • 0028484704 scopus 로고
    • MHC class 1-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
    • Yang Y, Ertl HCJ, Wilson JM. MHC class 1-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1994; 1: 433-442.
    • (1994) Immunity , vol.1 , pp. 433-442
    • Yang, Y.1    Ertl, H.C.J.2    Wilson, J.M.3
  • 10
    • 0029670374 scopus 로고    scopus 로고
    • Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs
    • Fang B et al. Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs. Gene Therapy 1996; 3: 217-222.
    • (1996) Gene Therapy , vol.3 , pp. 217-222
    • Fang, B.1
  • 11
    • 0028658416 scopus 로고
    • Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta E1 + delta E3) during multiple passages in 293 cells
    • Lochmuller HJ et al. Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta E1 + delta E3) during multiple passages in 293 cells. Hum Gene Ther 1994; 5: 1485-1491.
    • (1994) Hum Gene Ther , vol.5 , pp. 1485-1491
    • Lochmuller, H.J.1
  • 12
    • 0029582770 scopus 로고
    • A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions
    • Wang Q, Jia X-C, Finer MH. A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions. Gene Therapy 1995; 2: 775-783.
    • (1995) Gene Therapy , vol.2 , pp. 775-783
    • Wang, Q.1    Jia, X.-C.2    Finer, M.H.3
  • 13
    • 0022381043 scopus 로고
    • Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff
    • Halbert DN, Cutt JR, Shenk T. Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J Virol 1985; 56: 250-257.
    • (1985) J Virol , vol.56 , pp. 250-257
    • Halbert, D.N.1    Cutt, J.R.2    Shenk, T.3
  • 14
    • 0022624195 scopus 로고
    • Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression
    • Weinberg DH, Ketner G. Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression. J Virol 1986; 57: 833-838.
    • (1986) J Virol , vol.57 , pp. 833-838
    • Weinberg, D.H.1    Ketner, G.2
  • 16
    • 0024571586 scopus 로고
    • Redundant control of adenovirus late gene expression by early region 4
    • Bridge E, Ketner G. Redundant control of adenovirus late gene expression by early region 4. J Virol 1989; 63: 631-638.
    • (1989) J Virol , vol.63 , pp. 631-638
    • Bridge, E.1    Ketner, G.2
  • 17
    • 0020822949 scopus 로고
    • A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2
    • Weinberg DH, Ketner G. A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2. Proc Natl Acad Sci USA 1983; 80: 5383-5386.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 5383-5386
    • Weinberg, D.H.1    Ketner, G.2
  • 18
    • 0025019251 scopus 로고
    • Molecular mechanisms by which adenoviruses counteract antiviral immune defenses
    • Gooding LR, Wold WSM. Molecular mechanisms by which adenoviruses counteract antiviral immune defenses. Crit Rev Immunol 1990; 10: 53-71.
    • (1990) Crit Rev Immunol , vol.10 , pp. 53-71
    • Gooding, L.R.1    Wold, W.S.M.2
  • 19
    • 0023652362 scopus 로고
    • Developmental control of a promoter-specific factor that is also regulated by the E1A gene product
    • Reichel R, Kovesdi I, Nevins M Jr. Developmental control of a promoter-specific factor that is also regulated by the E1A gene product. Cell 1987; 48: 501-506.
    • (1987) Cell , vol.48 , pp. 501-506
    • Reichel, R.1    Kovesdi, I.2    Nevins Jr., M.3
  • 20
    • 0027193493 scopus 로고
    • Adenovirus early region 4 and viral DNA synthesis
    • Bridge EB et al. Adenovirus early region 4 and viral DNA synthesis. Virology 1993; 193: 794-801.
    • (1993) Virology , vol.193 , pp. 794-801
    • Bridge, E.B.1
  • 21
    • 0024504463 scopus 로고
    • Adenovirus early region 4 is essential for normal stability of late nuclear RNAs
    • Sandler AB, Ketner G. Adenovirus early region 4 is essential for normal stability of late nuclear RNAs. J Virol 1989; 63: 624-630.
    • (1989) J Virol , vol.63 , pp. 624-630
    • Sandler, A.B.1    Ketner, G.2
  • 22
    • 0027167564 scopus 로고
    • The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells
    • Chen PH, Ornelles DA, Shenk TJ. The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells. J Virol 1993; 67: 3507-3514.
    • (1993) J Virol , vol.67 , pp. 3507-3514
    • Chen, P.H.1    Ornelles, D.A.2    Shenk, T.J.3
  • 23
    • 0027475973 scopus 로고
    • Correction of deletion mutant using adenovirus vector
    • Wang Q, Taylor MW. Correction of deletion mutant using adenovirus vector. Mol Cell Biol 1993; 13: 918-927.
    • (1993) Mol Cell Biol , vol.13 , pp. 918-927
    • Wang, Q.1    Taylor, M.W.2
  • 24
    • 0029133392 scopus 로고
    • Gene targeting with a replication-defective adenovirus vector
    • Ayurni F, Keiko S, Yumi D, Izumu S, Ichizo K. Gene targeting with a replication-defective adenovirus vector. J Virol 1995; 69: 6180-6190.
    • (1995) J Virol , vol.69 , pp. 6180-6190
    • Ayurni, F.1    Keiko, S.2    Yumi, D.3    Izumu, S.4    Ichizo, K.5
  • 25
    • 0024601929 scopus 로고
    • Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids
    • Ketner G, Bridge E, Virtanen A, Hemstrom C, Pettersson U. Complementation of adenovirus E4 mutants by transient expression of E4 cDNA and deletion plasmids. Nucleic Acids Res 1989; 17: 3037-3048.
    • (1989) Nucleic Acids Res , vol.17 , pp. 3037-3048
    • Ketner, G.1    Bridge, E.2    Virtanen, A.3    Hemstrom, C.4    Pettersson, U.5
  • 26
    • 0020425067 scopus 로고
    • Adenovirus VA I RNA is required for efficient translation of viral mRNAs at late times after infection
    • Thimmappaya B, Weinberger C, Schneider RJ, Shenk T. Adenovirus VA I RNA is required for efficient translation of viral mRNAs at late times after infection. Cell 1982; 31: 543-551.
    • (1982) Cell , vol.31 , pp. 543-551
    • Thimmappaya, B.1    Weinberger, C.2    Schneider, R.J.3    Shenk, T.4
  • 27
    • 0029560716 scopus 로고
    • Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
    • Juillard V et al. Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector. Eur J Immnol 1995; 25: 3467-3473.
    • (1995) Eur J Immnol , vol.25 , pp. 3467-3473
    • Juillard, V.1
  • 28
    • 9244220682 scopus 로고    scopus 로고
    • Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo
    • Yang Y et al. Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Therapy 1996; 3: 137-144.
    • (1996) Gene Therapy , vol.3 , pp. 137-144
    • Yang, Y.1
  • 29
    • 0026484050 scopus 로고
    • Adenovirus-based expression vectors and recombinant vaccines
    • Ellis RW (ed). Butterworth-Heinemann: Boston, MA
    • Graham FL, Prevec L. Adenovirus-based expression vectors and recombinant vaccines. In: Ellis RW (ed). Vaccines: New Approaches to Immunological Problems. Butterworth-Heinemann: Boston, MA, 1992, pp 363-390.
    • (1992) Vaccines: New Approaches to Immunological Problems , pp. 363-390
    • Graham, F.L.1    Prevec, L.2
  • 30
    • 0027226234 scopus 로고
    • Separable regulatory elements governing myogenin transcription in mouse embryogenesis
    • Cheng T-C, Wallace MC, Merlie JP, Olson EN. Separable regulatory elements governing myogenin transcription in mouse embryogenesis. Science 1993; 261: 215-218.
    • (1993) Science , vol.261 , pp. 215-218
    • Cheng, T.-C.1    Wallace, M.C.2    Merlie, J.P.3    Olson, E.N.4
  • 31
    • 0023243262 scopus 로고
    • Histochemical staining of clonal mammalian cell lines expressing E. coli β-galactosidase indicate heterogeneous expression of the bacterial gene
    • MacGregor GR, Mogg AE, Burke JF, Caskey CT. Histochemical staining of clonal mammalian cell lines expressing E. coli β-galactosidase indicate heterogeneous expression of the bacterial gene. Somatic Cell Mol Genet 1987; 13: 253-264.
    • (1987) Somatic Cell Mol Genet , vol.13 , pp. 253-264
    • MacGregor, G.R.1    Mogg, A.E.2    Burke, J.F.3    Caskey, C.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.