-
1
-
-
0028899382
-
The gene as the drug
-
Crystal RG, The gene as the drug. Nature Med 1: 15-17, 1995.
-
(1995)
Nature Med
, vol.1
, pp. 15-17
-
-
Crystal, R.G.1
-
2
-
-
0025822386
-
Inherited hepatic enzyme defects as candidates for liver-directed gene therapy
-
Horwitz AL, Inherited hepatic enzyme defects as candidates for liver-directed gene therapy. Curr Top Microbiol Immunol 168: 185-200, 1991.
-
(1991)
Curr Top Microbiol Immunol
, vol.168
, pp. 185-200
-
-
Horwitz, A.L.1
-
3
-
-
0003720085
-
-
McGraw-Hill, New York
-
Scriver CR, Beaudet AL, Sly WS, Valle D (Eds.), The Metabolic Basis of Inherited Diseases. McGraw-Hill, New York, 1989.
-
(1989)
The Metabolic Basis of Inherited Diseases
-
-
Scriver, C.R.1
Beaudet, A.L.2
Sly, W.S.3
Valle, D.4
-
4
-
-
0027194576
-
In vivo delivery of human α1-antitrypsin gene to mouse hepatocytes by liposomes
-
Aliño SF, Bobadilla M, García-Sanz M, Lejarreta M, Unda F, and Hilario E, In vivo delivery of human α1-antitrypsin gene to mouse hepatocytes by liposomes. Biochem Biophys Res Commun 192: 174-181, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 174-181
-
-
Aliño, S.F.1
Bobadilla, M.2
García-Sanz, M.3
Lejarreta, M.4
Unda, F.5
Hilario, E.6
-
5
-
-
0023002524
-
Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition
-
Spanjer HH, van Galen M, Roerdink FH, Regts J and Scherphof GL, Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition. Biochim Biophys Acta 863: 224-230, 1986.
-
(1986)
Biochim Biophys Acta
, vol.863
, pp. 224-230
-
-
Spanjer, H.H.1
Van Galen, M.2
Roerdink, F.H.3
Regts, J.4
Scherphof, G.L.5
-
6
-
-
0030010148
-
Human α1-antitrypsin gene transfer to in vivo mouse hepatocytes
-
Aliño SF, Bobadilla M, Crespo J and Lejarreta M, Human α1-antitrypsin gene transfer to in vivo mouse hepatocytes. Hum Gene Ther 7: 531-536, 1996.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 531-536
-
-
Aliño, S.F.1
Bobadilla, M.2
Crespo, J.3
Lejarreta, M.4
-
7
-
-
0028172344
-
Expression of human α1-antitrypsin in mouse after in vivo gene transfer to hepatocytes by small liposomes
-
Alino SF, Crespo J, Bobadilla M, Lejarreta M, Blaya C and Crespo A, Expression of human α1-antitrypsin in mouse after in vivo gene transfer to hepatocytes by small liposomes. Biochem Biophys Res Commun 204: 1023-1030, 1994.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1023-1030
-
-
Alino, S.F.1
Crespo, J.2
Bobadilla, M.3
Lejarreta, M.4
Blaya, C.5
Crespo, A.6
-
8
-
-
0029898019
-
Long-term expression of the human α1-antitrypsin gene in mice employing anionic and cationic liposome vectors
-
Crespo J, Blaya C, Crespo A and Aliño SF, Long-term expression of the human α1-antitrypsin gene in mice employing anionic and cationic liposome vectors. Biochem Pharmacol 51: 1309-1314, 1996.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 1309-1314
-
-
Crespo, J.1
Blaya, C.2
Crespo, A.3
Aliño, S.F.4
-
9
-
-
0028223310
-
Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
-
Perales JC, Ferkol T, Beegen H, Ratnoff OD and Hanson RW, Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci USA 91: 4086-4090, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4086-4090
-
-
Perales, J.C.1
Ferkol, T.2
Beegen, H.3
Ratnoff, O.D.4
Hanson, R.W.5
-
10
-
-
0027164681
-
pH-Sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells
-
Straubinger RM, pH-Sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells. Methods Enzymol 221: 361-370, 1993.
-
(1993)
Methods Enzymol
, vol.221
, pp. 361-370
-
-
Straubinger, R.M.1
-
11
-
-
0027313072
-
Systemic gene expression after intravenous DNA delivery into adult mice
-
Zhu N, Liggitt D, Liu Y and Debs R, Systemic gene expression after intravenous DNA delivery into adult mice. Science 261: 209-211, 1993.
-
(1993)
Science
, vol.261
, pp. 209-211
-
-
Zhu, N.1
Liggitt, D.2
Liu, Y.3
Debs, R.4
-
12
-
-
0029658116
-
High yield incorporation of plasmid DNA within liposomes: Effect on DNA integrity and transfection efficiency
-
Gregoriadis G, Saffie R and Hart SL, High yield incorporation of plasmid DNA within liposomes: Effect on DNA integrity and transfection efficiency. J Drug Target 3: 469-475, 1996.
-
(1996)
J Drug Target
, vol.3
, pp. 469-475
-
-
Gregoriadis, G.1
Saffie, R.2
Hart, S.L.3
-
13
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM and Danielsen M, Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 84: 7413-7417, 1987.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
Roman, R.4
Chan, H.W.5
Wenz, M.6
Northrop, J.P.7
Ringold, G.M.8
Danielsen, M.9
-
14
-
-
0028024919
-
Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations
-
Felgner JH, Kumar R, Sridhar CN, Wheeler CJ, Tasi YJ, Border R, Ramsey P, Martin M and Feigner PL, Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 269: 2550-2561, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 2550-2561
-
-
Felgner, J.H.1
Kumar, R.2
Sridhar, C.N.3
Wheeler, C.J.4
Tasi, Y.J.5
Border, R.6
Ramsey, P.7
Martin, M.8
Feigner, P.L.9
-
15
-
-
0026180387
-
Use of liposomes, viral capsids and nanoparticles as DNA carriers
-
Bertling WM, Gareis M, Paspaleeva B, Zimmer A, Kreuter J, Nurnberg E and Harrer P, Use of liposomes, viral capsids and nanoparticles as DNA carriers. Biotechnol Appl Biochem 13: 390-405, 1991.
-
(1991)
Biotechnol Appl Biochem
, vol.13
, pp. 390-405
-
-
Bertling, W.M.1
Gareis, M.2
Paspaleeva, B.3
Zimmer, A.4
Kreuter, J.5
Nurnberg, E.6
Harrer, P.7
-
16
-
-
0026786522
-
Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: Comparison with cationic liposomes
-
Legendre JY and Szoka FC Jr, Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: Comparison with cationic liposomes. Pharm Res 9: 1235-1242, 1992.
-
(1992)
Pharm Res
, vol.9
, pp. 1235-1242
-
-
Legendre, J.Y.1
Szoka F.C., Jr.2
-
17
-
-
0023055082
-
pH-Dependent lysis of liposomes by adenovirus
-
Blumenthal R, Seth P, Willingham MC and Pastan I, pH-Dependent lysis of liposomes by adenovirus. Biochemistry 25: 2231-2237, 1986.
-
(1986)
Biochemistry
, vol.25
, pp. 2231-2237
-
-
Blumenthal, R.1
Seth, P.2
Willingham, M.C.3
Pastan, I.4
-
18
-
-
0025949812
-
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery
-
Curiel DT, Agarwal S, Wagner E and Cotten M, Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. Proc Natl Acad Sci USA 88: 8850-8854, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8850-8854
-
-
Curiel, D.T.1
Agarwal, S.2
Wagner, E.3
Cotten, M.4
-
19
-
-
0027447460
-
Hepatic gene therapy: Adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes
-
Cristiano RJ, Smith LC and Woo SL, Hepatic gene therapy: Adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes. Proc Natl Acad Sci USA 90: 2122-2126, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2122-2126
-
-
Cristiano, R.J.1
Smith, L.C.2
Woo, S.L.3
-
20
-
-
0343869965
-
Liposomes for gene therapy
-
Eds. Puissieux F, Couvreur P, Delattre J and Devissaugnet JP. Editions de Santé, Paris
-
Legendre JY and Szoka FC Jr, Liposomes for gene therapy. In: Liposomes, New Systems and New Trends in Their Applications (Eds. Puissieux F, Couvreur P, Delattre J and Devissaugnet JP), pp. 669-692. Editions de Santé, Paris, 1995.
-
(1995)
Liposomes, New Systems and New Trends in Their Applications
, pp. 669-692
-
-
Legendre, J.Y.1
Szoka F.C., Jr.2
-
21
-
-
0028842728
-
Engineering liposomes for drug delivery: Progress and problems
-
Gregoriadis G, Engineering liposomes for drug delivery: Progress and problems. Trends Biotechnol 13: 527-537, 1995.
-
(1995)
Trends Biotechnol
, vol.13
, pp. 527-537
-
-
Gregoriadis, G.1
-
22
-
-
0011269588
-
In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin 1
-
Nicolau C, Le Pape A, Soriano P, Fargette F and Juhel MF, In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin 1. Proc Natl Acad Sci USA 80: 1068-1072, 1983.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 1068-1072
-
-
Nicolau, C.1
Le Pape, A.2
Soriano, P.3
Fargette, F.4
Juhel, M.F.5
-
23
-
-
0017143620
-
Interaction of liposomes with blood plasma proteins
-
Black CDV and Gregoriadis G, Interaction of liposomes with blood plasma proteins. Biochem Soc Trans 4: 253-256, 1976.
-
(1976)
Biochem Soc Trans
, vol.4
, pp. 253-256
-
-
Black, C.D.V.1
Gregoriadis, G.2
-
24
-
-
0026315433
-
Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats
-
Wu GY, Wilson JM, Shalaby F, Grossman M, Shafritz DA and Wu CH, Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J Biol Chem 266: 14338-14342, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 14338-14342
-
-
Wu, G.Y.1
Wilson, J.M.2
Shalaby, F.3
Grossman, M.4
Shafritz, D.A.5
Wu, C.H.6
-
25
-
-
0025098539
-
Similar induction of the hepatic EGF receptor in vivo by EGF and partial hepatectomy
-
Johansson S and Andersson G, Similar induction of the hepatic EGF receptor in vivo by EGF and partial hepatectomy. Biochem Biophys Res Commun 166: 661-666, 1990.
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 661-666
-
-
Johansson, S.1
Andersson, G.2
-
26
-
-
0026722109
-
A novel mechanism for achieving transgene persistence in vivo after somatic transfer into hepatocytes
-
Wilson JM, Grassman M, Cabrera JA, Wu CH and Wu GY, A novel mechanism for achieving transgene persistence in vivo after somatic transfer into hepatocytes. J Biol Chem 267: 11483-11489, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 11483-11489
-
-
Wilson, J.M.1
Grassman, M.2
Cabrera, J.A.3
Wu, C.H.4
Wu, G.Y.5
-
27
-
-
0029147628
-
Nonviral gene therapy: The promise of genes as pharmaceutical products
-
Ledley FD, Nonviral gene therapy: The promise of genes as pharmaceutical products. Hum Gene Ther 6: 1129-1144, 1995.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1129-1144
-
-
Ledley, F.D.1
-
28
-
-
0027233696
-
Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy
-
Chowdhury NR, Wu CH, Wu GY, Yerneni PC, Bomminen VR and Chowdhury JR, Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy. J Biol Chem 268: 11265-11271, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 11265-11271
-
-
Chowdhury, N.R.1
Wu, C.H.2
Wu, G.Y.3
Yerneni, P.C.4
Bomminen, V.R.5
Chowdhury, J.R.6
-
29
-
-
0025719339
-
Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats
-
Kato K, Kaneda Y, Sakurai M, Nakanishi M and Okada Y, Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats. J Biol Chem 266: 22071-22074, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 22071-22074
-
-
Kato, K.1
Kaneda, Y.2
Sakurai, M.3
Nakanishi, M.4
Okada, Y.5
-
30
-
-
0024597585
-
Increased expression of DNA cointroduced with nuclear protein in adult rat liver
-
Kaneda Y, Iwai K and Uchida T, Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science 243: 375-378, 1989.
-
(1989)
Science
, vol.243
, pp. 375-378
-
-
Kaneda, Y.1
Iwai, K.2
Uchida, T.3
-
31
-
-
0025857661
-
Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified method
-
Kato K, Nakanishi M, Kaneda Y, Uchida T and Okada Y, Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified method. J Biol Chem 266: 3361-3364, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 3361-3364
-
-
Kato, K.1
Nakanishi, M.2
Kaneda, Y.3
Uchida, T.4
Okada, Y.5
-
32
-
-
0026128054
-
Evaluation of relative promoter strength in primary hepatocytes using optimized lipofection
-
Ponder KP, Dunbar RP, Wilson DR, Darlington GJ and Woo SLC, Evaluation of relative promoter strength in primary hepatocytes using optimized lipofection. Hum Gene Ther 2: 41-52, 1991.
-
(1991)
Hum Gene Ther
, vol.2
, pp. 41-52
-
-
Ponder, K.P.1
Dunbar, R.P.2
Wilson, D.R.3
Darlington, G.J.4
Woo, S.L.C.5
-
33
-
-
0026586140
-
Expression of human α1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes
-
Kay MA, Baley P, Rothenberg S, Leland F, Fleming L, Ponder KP, Liu T-j, Finegold M, Darlington G, Pokorny W and Woo SLC, Expression of human α1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes. Proc Natl Acad Sci USA 89: 89-93, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 89-93
-
-
Kay, M.A.1
Baley, P.2
Rothenberg, S.3
Leland, F.4
Fleming, L.5
Ponder, K.P.6
Liu, T.-J.7
Finegold, M.8
Darlington, G.9
Pokorny, W.10
Woo, S.L.C.11
-
34
-
-
0025753128
-
Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants
-
Scharfmann R, Axelrod H and Verma IM, Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants. Proc Natl Acad Sci USA 88: 4626-4630, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4626-4630
-
-
Scharfmann, R.1
Axelrod, H.2
Verma, I.M.3
-
35
-
-
0024556589
-
Construction of an EBNA-producing line of well-differentiated human hepatoma cells and appropriate Epstein-Barr virus-based shuttle
-
Lutfalla G, Armbrust L, Dequin S and Bertolotti R, Construction of an EBNA-producing line of well-differentiated human hepatoma cells and appropriate Epstein-Barr virus-based shuttle. Gene 76: 27-39, 1989.
-
(1989)
Gene
, vol.76
, pp. 27-39
-
-
Lutfalla, G.1
Armbrust, L.2
Dequin, S.3
Bertolotti, R.4
|