Gene therapy with bilirubin-UDP-glucuronosyltransferase in the Gunn rat model of Crigler-Najjar syndrome type 1

Human Gene Therapy

Volumn 9, Issue 4, 1998, Pages 497-505

  Li, Qianhong ^a   Murphree, Sidney S ^a   Willer, Sharon S ^a   Bolli, Roberto ^a   French, Brent A ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; COMPLEMENTARY DNA; GLUCURONOSYLTRANSFERASE; VIRUS VECTOR;

ADENOVIRUS 5; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; GENE MUTATION; GENE THERAPY; GENE TRANSFER; HETEROZYGOSITY; HOMOZYGOSITY; JAUNDICE; LIVER HISTOLOGY; NEWBORN; NONHUMAN; RAT; STOP CODON;

ADENOVIRIDAE; ANIMALIA; HUMAN ADENOVIRUS TYPE 5; RATTUS NORVEGICUS; RODENTIA;

EID: 0032032633     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.4-497     Document Type: Article

References (6)

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2. ASKARI, F., HITOMI, E., THINEY, M., and WILSON, J.M. (1995). Retrovirus-mediated expression of HUG Br1 in Crigler-Najjar syndrome type I human fibroblasts and correction of the genetic defect in Gunn rat hepatocytes. Gene Ther. 2, 203-208.
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