Characterization of CYP2A6 involved in 3′-hydroxylation of cotinine in human liver microsomes

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 2, 1996, Pages 1010-1015

  Nakajima, Miki ^a   Yamamoto, Toshinori ^a   Nunoya, Ken Ichi ^b   Yokoi, Tsuyoshi ^b   Nagashima, Kazuo ^c   Inoue, Kazuaki ^d   Funae, Yoshihiko ^e   Shimada, Noriaki ^f   Kamataki, Tetsuya ^b   Kuroiwa, Yukio ^a  

^a SHOWA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^e OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXYCOUMARIN; ALPHA NAPHTHOFLAVONE; CHLORZOXAZONE; COTININE; COUMARIN; CYTOCHROME P450; ERYTHROMYCIN; IMMUNOGLOBULIN G ANTIBODY; MEPHENYTOIN; OXYGENASE; QUINIDINE; TOLBUTAMIDE;

ARTICLE; CIGARETTE SMOKING; DRUG HYDROXYLATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; LIVER METABOLISM; LIVER MICROSOME; LYMPHOBLASTOID CELL; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; COTININE; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROXYLATION; ISOENZYMES; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES;

EID: 5544281923     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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