-
1
-
-
0029996292
-
Warfarin-fluconazole. II. A metabolically based drug interaction: In vivo studies
-
D. J. Black, K. L. Kunze, L. C. Wienkers, B. E. Gidal, T. L. Seaton, N. D. McDonnell, J. S. Evans, J. E. Bauwens, and W. F. Trager: Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies. Drug Metab. Dispos. 24, 422-428 (1996).
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 422-428
-
-
Black, D.J.1
Kunze, K.L.2
Wienkers, L.C.3
Gidal, B.E.4
Seaton, T.L.5
McDonnell, N.D.6
Evans, J.S.7
Bauwens, J.E.8
Trager, W.F.9
-
2
-
-
0029877219
-
Inhibition of the human cytochrome P-450 enzymes responsible for the metabolism of warfarin by fluconazole. I. in vitro studies
-
K. L. Kunze, L. C. Weinkers, K. E. Thummel, and W. F. Trager: Inhibition of the human cytochrome P-450 enzymes responsible for the metabolism of warfarin by fluconazole. I. In vitro studies. Drug Metab. Dispos. 24, 414-421 (1996).
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 414-421
-
-
Kunze, K.L.1
Weinkers, L.C.2
Thummel, K.E.3
Trager, W.F.4
-
3
-
-
0026802087
-
Drug interactions with warfarin
-
N. A. Buckley and A. H. Dawson: Drug interactions with warfarin. Med. J. Aust 157, 479-483 (1992).
-
(1992)
Med. J. Aust
, vol.157
, pp. 479-483
-
-
Buckley, N.A.1
Dawson, A.H.2
-
4
-
-
0016220245
-
Studies of the optical enantiomorphs of warfarin in man
-
R. A. O'Reilly: Studies of the optical enantiomorphs of warfarin in man. Clin. Pharmacol. Ther. 16, 348-354 (1974).
-
(1974)
Clin. Pharmacol. Ther.
, vol.16
, pp. 348-354
-
-
O'Reilly, R.A.1
-
5
-
-
0015790825
-
Plasma half-lives, plasma metabolites and the anticoagulant efficacies of the enantiomers of warfarin in man
-
D. S. Hewick and J. McEwen: Plasma half-lives, plasma metabolites and the anticoagulant efficacies of the enantiomers of warfarin in man. J. Pharm. Pharmacol. 25, 455-465 (1973).
-
(1973)
J. Pharm. Pharmacol.
, vol.25
, pp. 455-465
-
-
Hewick, D.S.1
McEwen, J.2
-
6
-
-
0017841470
-
Pharmacokinetics of warfarin enantiomers: A search for intrasubject correlations
-
L. B. Wingard, R. A. O'Reilly, and G. Levy: Pharmacokinetics of warfarin enantiomers: a search for intrasubject correlations. Clin. Pharmacol. Ther. 23, 212-217 (1978).
-
(1978)
Clin. Pharmacol. Ther.
, vol.23
, pp. 212-217
-
-
Wingard, L.B.1
O'Reilly, R.A.2
Levy, G.3
-
7
-
-
0022997648
-
Clinical pharmacokinetics and pharmacodynamics of warfarin: Understanding the dose-effect relationship
-
N. H. G. Holford: Clinical pharmacokinetics and pharmacodynamics of warfarin: understanding the dose-effect relationship. Clin. Pharmacokinet. 11, 483-504 (1986).
-
(1986)
Clin. Pharmacokinet.
, vol.11
, pp. 483-504
-
-
Holford, N.H.G.1
-
8
-
-
0018294103
-
Pharmacokinetics and pharmacodynamics of warfarin at steady state
-
P. A. Routledge, P. H. Chapman, D. M. Davies, and M. D. Rawlins: Pharmacokinetics and pharmacodynamics of warfarin at steady state. Br. J. Clin. Pharmacol. 8, 243-247 (1979).
-
(1979)
Br. J. Clin. Pharmacol.
, vol.8
, pp. 243-247
-
-
Routledge, P.A.1
Chapman, P.H.2
Davies, D.M.3
Rawlins, M.D.4
-
9
-
-
0022964492
-
The negative impact of biological variation in the effect and clearance of warfarin on methods for prediction of dose requirements
-
P. Weiss, H. Halkin, and S. Almog: The negative impact of biological variation in the effect and clearance of warfarin on methods for prediction of dose requirements. Thromb. Haemost. 56, 371-375 (1986).
-
(1986)
Thromb. Haemost.
, vol.56
, pp. 371-375
-
-
Weiss, P.1
Halkin, H.2
Almog, S.3
-
10
-
-
0026627837
-
A comparison of the relative sensitivities of factor VII and prothrombin time measurements in detecting drug interactions with warfarin
-
M. Pitsiu, E. M. Parker, L. Aarons, B. Holt, and M. Rowland: A comparison of the relative sensitivities of factor VII and prothrombin time measurements in detecting drug interactions with warfarin. Eur. J. Clin. Pharmacol. 42, 645-650 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.42
, pp. 645-650
-
-
Pitsiu, M.1
Parker, E.M.2
Aarons, L.3
Holt, B.4
Rowland, M.5
-
11
-
-
0026519541
-
Hydroxylation of warfarin by human cDNA expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin drug interactions
-
A. E. Rettie, K. R. Korzekwa, K. L. Kunze, R. F. Lawrence, A. C. Eddy, T. Aoyama, H. V. Gelboin, F. J. Gonzalez, and W. F. Trager: Hydroxylation of warfarin by human cDNA expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin drug interactions. Chem. Res. Toxicol. 5, 54-59 (1992).
-
(1992)
Chem. Res. Toxicol.
, vol.5
, pp. 54-59
-
-
Rettie, A.E.1
Korzekwa, K.R.2
Kunze, K.L.3
Lawrence, R.F.4
Eddy, A.C.5
Aoyama, T.6
Gelboin, H.V.7
Gonzalez, F.J.8
Trager, W.F.9
-
12
-
-
0025363182
-
Fluconazole: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in superficial and systemic mycoses
-
S. M. Grant and S. P. Clissold: Fluconazole: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in superficial and systemic mycoses. Drugs 39, 877-914 (1990).
-
(1990)
Drugs
, vol.39
, pp. 877-914
-
-
Grant, S.M.1
Clissold, S.P.2
-
13
-
-
0025219525
-
Drug interactions with fluconazole
-
J. D. Lazar and K. D. Wilner: Drug interactions with fluconazole. Rev. Inf. Dis. 12, S327-S333 (1990).
-
(1990)
Rev. Inf. Dis.
, vol.12
-
-
Lazar, J.D.1
Wilner, K.D.2
-
15
-
-
0023423538
-
Kinetics of drug metabolism inhibition: Use of metabolic concentration-time profiles
-
P. N. Shaw and J. B. Houston: Kinetics of drug metabolism inhibition: use of metabolic concentration-time profiles. J. Pharmacokinet. Biopharm. 15, 497-510 (1987).
-
(1987)
J. Pharmacokinet. Biopharm.
, vol.15
, pp. 497-510
-
-
Shaw, P.N.1
Houston, J.B.2
-
16
-
-
0023097223
-
Plasma concentration-response relationship for cimetidine inhibition of drug metabolism in the rat
-
A. Adedayo, L. E. Aarons, and J. B. Houston: Plasma concentration-response relationship for cimetidine inhibition of drug metabolism in the rat. Drug Metab. Dispos. 15, 127-132 (1987).
-
(1987)
Drug Metab. Dispos.
, vol.15
, pp. 127-132
-
-
Adedayo, A.1
Aarons, L.E.2
Houston, J.B.3
-
17
-
-
0022655468
-
The warfarin-sulfinpyrazone interaction: Stereochemical considerations
-
S. Toon, L. K. Low, M. Gibaldi, W. F. Trager, R. A. O'Reilly, C. H. Notley, and D. A. Goulart: The warfarin-sulfinpyrazone interaction: stereochemical considerations. Clin. Pharmacol. Ther. 39, 15-24 (1986).
-
(1986)
Clin. Pharmacol. Ther.
, vol.39
, pp. 15-24
-
-
Toon, S.1
Low, L.K.2
Gibaldi, M.3
Trager, W.F.4
O'Reilly, R.A.5
Notley, C.H.6
Goulart, D.A.7
-
18
-
-
0026575955
-
The mechanism of the interaction between amiodarone and warfarin in humans
-
L. D. Heimark, L. C. Wienkers, K. L. Kunze, M. Gibaldi, A. C. Eddy, W. F. Trager, R. A. O'Reilly, and D. A. Goulart: The mechanism of the interaction between amiodarone and warfarin in humans. Clin. Pharmacol. Ther. 51, 398-407 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 398-407
-
-
Heimark, L.D.1
Wienkers, L.C.2
Kunze, K.L.3
Gibaldi, M.4
Eddy, A.C.5
Trager, W.F.6
O'Reilly, R.A.7
Goulart, D.A.8
-
19
-
-
0026763432
-
Mechanisms of the stereoselective interaction between miconazole and racemic warfarin in human subjects
-
R. A. O'Reilly, D. A. Goulart, K. L. Kunze, J. Neal, M. Gibaldi, A. C. Eddy, and W. F. Trager: Mechanisms of the stereoselective interaction between miconazole and racemic warfarin in human subjects. Clin. Pharmacol. Ther. 51, 656-667 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 656-667
-
-
O'Reilly, R.A.1
Goulart, D.A.2
Kunze, K.L.3
Neal, J.4
Gibaldi, M.5
Eddy, A.C.6
Trager, W.F.7
-
21
-
-
0027439883
-
Lowdose fluconazole therapy potentiates the hypoprothrominemic response of warfarin sodium
-
L. L. Crussell-Porter, J. P. Rindone, M. A. Ford, and D. W. Jaskar: Lowdose fluconazole therapy potentiates the hypoprothrominemic response of warfarin sodium. Arch. Intern. Med. 153, 102-104 (1993).
-
(1993)
Arch. Intern. Med.
, vol.153
, pp. 102-104
-
-
Crussell-Porter, L.L.1
Rindone, J.P.2
Ford, M.A.3
Jaskar, D.W.4
-
22
-
-
0025320774
-
Theophylline dosage adjustment during enoxacin coadministration
-
J. R. Koup, R. D. Toothaker, E. Posvar, A. J. Sedman, and W. A. Colburn: Theophylline dosage adjustment during enoxacin coadministration. Antimicrob. Agents Chemother. 34, 803-807 (1990).
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 803-807
-
-
Koup, J.R.1
Toothaker, R.D.2
Posvar, E.3
Sedman, A.J.4
Colburn, W.A.5
-
23
-
-
0025801514
-
Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9
-
M. E. Veronese, P. I. Mackenzie, C. J. Doecke, M. E. McManus, J. O. Miners, and D. J. Birken: Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9. Biochem. Biophys. Res. Comm. 175, 1112-1118 (1991).
-
(1991)
Biochem. Biophys. Res. Comm.
, vol.175
, pp. 1112-1118
-
-
Veronese, M.E.1
Mackenzie, P.I.2
Doecke, C.J.3
McManus, M.E.4
Miners, J.O.5
Birken, D.J.6
-
24
-
-
0027397054
-
Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily
-
M. E. Veronese, C. J. Doecke, P. I. Mackenzie, M. E. McManus, J. O. Miners, D. L. Rees, R. Gasser, U. A. Meyer, and D. J. Birkett: Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily. Biochem. J. 289, 533-538 (1993).
-
(1993)
Biochem. J.
, vol.289
, pp. 533-538
-
-
Veronese, M.E.1
Doecke, C.J.2
Mackenzie, P.I.3
McManus, M.E.4
Miners, J.O.5
Rees, D.L.6
Gasser, R.7
Meyer, U.A.8
Birkett, D.J.9
-
25
-
-
0028210729
-
Impaired (S)-warfarin metabolism catalyzed by the R144C allelic variant of CYP2C9
-
A. E. Rettie, L. C. Wienkers, F. J. Gonzalez, W. F. Trager, and K. R. Korzekwa. Impaired (S)-warfarin metabolism catalyzed by the R144C allelic variant of CYP2C9. Pharmacogenetics 4, 39-42 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 39-42
-
-
Rettie, A.E.1
Wienkers, L.C.2
Gonzalez, F.J.3
Trager, W.F.4
Korzekwa, K.R.5
-
26
-
-
0025264682
-
Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabotizers
-
M. E. Veronese, J. O. Miners, D. Randles, D. Gregov, and D. J. Birkett: Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabotizers. Clin. Pharmacol. Ther. 47, 403-411 (1990).
-
(1990)
Clin. Pharmacol. Ther.
, vol.47
, pp. 403-411
-
-
Veronese, M.E.1
Miners, J.O.2
Randles, D.3
Gregov, D.4
Birkett, D.J.5
-
27
-
-
0023924549
-
In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines
-
D. J. Back, J. F. Tjia, J. Karbwang, and J. Colbert: In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines. Br. J. Clin. Pharmacol. 26, 23-29 (1988).
-
(1988)
Br. J. Clin. Pharmacol.
, vol.26
, pp. 23-29
-
-
Back, D.J.1
Tjia, J.F.2
Karbwang, J.3
Colbert, J.4
-
28
-
-
0028283319
-
Disposition of azole antifungal agents. III. Binding of fluconazole and other azoles in rat liver
-
C. M. Ervine and J. B. Houston: Disposition of azole antifungal agents. III. Binding of fluconazole and other azoles in rat liver. Pharmaceut. Res. 11, 961-965 (1994).
-
(1994)
Pharmaceut. Res.
, vol.11
, pp. 961-965
-
-
Ervine, C.M.1
Houston, J.B.2
-
29
-
-
0025760346
-
Effect of fluconazole on the disposition of phenytoin
-
R. A. Blum, J. H. Wilton, D. M. Hilligoss, M. J. Gardner, E. B. Henry, N. J. Harrison, and J. J. Schentag: Effect of fluconazole on the disposition of phenytoin. Clin. Pharmacol. Ther. 4, 420-425 (1991).
-
(1991)
Clin. Pharmacol. Ther.
, vol.4
, pp. 420-425
-
-
Blum, R.A.1
Wilton, J.H.2
Hilligoss, D.M.3
Gardner, M.J.4
Henry, E.B.5
Harrison, N.J.6
Schentag, J.J.7
|