-
1
-
-
0034614637
-
The hallmarks of cancer
-
ANAHAN D, WEINBERG RA: The hallmarks of cancer. Cell (2000) 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Anahan, D.1
Weinberg, R.A.2
-
2
-
-
0027254069
-
How many mutations are required for tumorogenesis? Implications from human cancer data
-
RENAN MJ: How many mutations are required for tumorogenesis? Implications from human cancer data. Mol Carcinogenesis (1993) 7:139-146.
-
(1993)
Mol Carcinogenesis
, vol.7
, pp. 139-146
-
-
Renan, M.J.1
-
3
-
-
0031771470
-
Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorige-nesis
-
BERGERS G, HANAHAN D, COUSSES LM: Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorige-nesis. Int. J. Dev. Biol. (1998). 42:995-1002.
-
(1998)
Int. J. Dev. Biol.
, vol.42
, pp. 995-1002
-
-
Bergers, G.1
Hanahan, D.2
Cousses, L.M.3
-
4
-
-
0032524104
-
Landscaping the cancer terrain
-
KINZLER KW, VOGELSTEIN B: Landscaping the cancer terrain. Science (1998) 280:1036-1037.
-
(1998)
Science
, vol.280
, pp. 1036-1037
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
5
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
KNUDSON AG: Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA (1971) 68:820-823.
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
6
-
-
0033614998
-
Creation of human tumor cells with defined genetic elements
-
HAHN WC, COUNTER CM, LUNDBERG AS et al: Creation of human tumor cells with defined genetic elements. Nature (1999) 400:464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
-
7
-
-
0004273069
-
-
Scientific American, Inc., New York, USA
-
Molecular Oncology. Bishop JM, Weinberg RA (Eds.), Scientific American, Inc., New York, USA (1996).
-
(1996)
Molecular Oncology
-
-
Bishop, J.M.1
Weinberg, R.A.2
-
8
-
-
0026335851
-
Loss of constitutional heterozygosity in human cancer
-
LASKOD, CAVENEE W, NORDENSKJOLD M: Loss of constitutional heterozygosity in human cancer. Ann. Rev. Genet. (1991) 25:281-314.
-
(1991)
Ann. Rev. Genet.
, vol.25
, pp. 281-314
-
-
Laskod1
Cavenee, W.2
Nordenskjold, M.3
-
9
-
-
0027313470
-
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
-
ZHU L, VAN DEN HEUVEL S, HELIN K et al: Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev. (1993) 7:1111-1125.
-
(1993)
Genes Dev.
, vol.7
, pp. 1111-1125
-
-
Zhu, L.1
Van Den Heuvel, S.2
Helin, K.3
-
10
-
-
0028143074
-
P130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107
-
CLAUDIO PP, HOWARD CM, BALDI A et al: p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107
-
(1994)
Cancer Res.
, vol.54
, pp. 5556-5560
-
-
Claudio, P.P.1
Howard, C.M.2
Baldi, A.3
-
11
-
-
0029896193
-
Transcriptional repression and growth suppression by the p107 pocket protein
-
STAROSTIK P, CHOW KNB, DEAN DC: Transcriptional repression and growth suppression by the p107 pocket protein. Mol. Cell. Biol. (1996) 16:3606-3614.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3606-3614
-
-
Starostik, P.1
Knb, C.2
Dean, D.C.3
-
12
-
-
0034650850
-
Mutations in the retinoblastoma-related gene Rb2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer
-
CLAUDIO PP, HOWARD CM, PACILIO C et al: Mutations in the retinoblastoma-related gene Rb2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer. Cancer Res. (2000) 60:372-382.
-
(2000)
Cancer Res.
, vol.60
, pp. 372-382
-
-
Claudio, P.P.1
Howard, C.M.2
Pacilio, C.3
-
13
-
-
0024234852
-
Suppression of the neoplastic phenotype by replacement of the Rb gene in human cancer cells
-
HUANG HJ, YEE JK, SHEW JY et al: Suppression of the neoplastic phenotype by replacement of the Rb gene in human cancer cells. Science (1988) 242:1563-1566.
-
(1988)
Science
, vol.242
, pp. 1563-1566
-
-
Huang, H.J.1
Yee, J.K.2
Shew, J.Y.3
-
14
-
-
0021914111
-
Genetic origin of mutations predisposing to retinoblastoma
-
CAVENEE WK, HANSEN MF, NORDENSKJOLD M et al: Genetic origin of mutations predisposing to retinoblastoma. Science (1985) 228:501-503.
-
(1985)
Science
, vol.228
, pp. 501-503
-
-
Cavenee, W.K.1
Hansen, M.F.2
Nordenskjold, M.3
-
15
-
-
0029931681
-
Genomic structure of the human retinoblastoma-related Rb2/p130 gene
-
BALDI A, BOCCIA V, CLAUDIO PP, DE LUCA A, GIORDANO A: Genomic structure of the human retinoblastoma-related Rb2/p130 gene. Proc. Natl. Acad. Sci. USA (1996.) 93:4629-4632.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4629-4632
-
-
Baldi, A.1
Boccia, V.2
Claudio, P.P.3
De Luca, A.4
Giordano, A.5
-
16
-
-
0027382340
-
The retinoblastoma-related gene, Rb2, maps to human chromosomes 16q12 and rate chromosome 19
-
YEUNG RS, BELL DW, TESTA JR et al.: The retinoblastoma-related gene, Rb2, maps to human chromosomes 16q12 and rate chromosome 19. Oncogene (1993) 8:3465-3458.
-
(1993)
Oncogene
, vol.8
, pp. 3465-3458
-
-
Yeung, R.S.1
Bell, D.W.2
Testa, J.R.3
-
17
-
-
0026337295
-
Tumor suppressor genes
-
WEINBERG RA: Tumor suppressor genes. Science (1991) 254:1138-1145.
-
(1991)
Science
, vol.254
, pp. 1138-1145
-
-
Weinberg, R.A.1
-
18
-
-
0034323581
-
The Rb family of cell cycle regulatory factors: Clinical implications
-
MASCIULLO V, KHALILI K, GIORDANO A: The Rb family of cell cycle regulatory factors: clinical implications. Int. J. Oncol. (2000) 17:897-902.
-
(2000)
Int. J. Oncol.
, vol.17
, pp. 897-902
-
-
Masciullo, V.1
Khalili, K.2
Giordano, A.3
-
19
-
-
0029152374
-
The roles of tumor suppressors pRb and p53 in cell proliferation and cancer
-
SANG N, BALDI A, GIORDANO A: The roles of tumor suppressors pRb and p53 in cell proliferation and cancer. Mol. Cell. Diff. (1995) 3:1-29.
-
(1995)
Mol. Cell. Diff.
, vol.3
, pp. 1-29
-
-
Sang, N.1
Baldi, A.2
Giordano, A.3
-
20
-
-
0028788975
-
Familial cylindro-matosis (turban tumor syndrome) gene localised to chromosome 16q12-q13: Evidence for its role as tumor suppressor gene
-
BIGGS PJ, WOOSTER R, FORD D et al: Familial cylindro-matosis (turban tumor syndrome) gene localised to chromosome 16q12-q13: evidence for its role as tumor suppressor gene. Nature Genet (1995) 11:441-443.
-
(1995)
Nature Genet
, vol.11
, pp. 441-443
-
-
Biggs, P.J.1
Wooster, R.2
Ford, D.3
-
21
-
-
0034650581
-
Genetic alteration disrupting the nuclear localization of the retinoblastoma-related gene of Rb2/p130 in human tumor cell lines and primary tumors
-
CINTI C, CLAUDIO PP, HOWARD CM et al: Genetic alteration disrupting the nuclear localization of the retinoblastoma-related gene of Rb2/p130 in human tumor cell lines and primary tumors. Cancer Res. (2000) 60:383-389.
-
(2000)
Cancer Res.
, vol.60
, pp. 383-389
-
-
Cinti, C.1
Claudio, P.P.2
Howard, C.M.3
-
22
-
-
0033873789
-
Genetic alterations of the retinoblastoma related gene Rb2/p130 identify different pathogenetic mechanisms in and among Burkitt's lymphoma subtypes
-
CINTI C, LEONCINI L, NWONGO A et al: Genetic alterations of the retinoblastoma related gene Rb2/p130 identify different pathogenetic mechanisms in and among Burkitt's lymphoma subtypes. Am. J. Pathol (2000) 156:751-760.
-
(2000)
Am. J. Pathol
, vol.156
, pp. 751-760
-
-
Cinti, C.1
Leoncini, L.2
Nwongo, A.3
-
23
-
-
0033954975
-
Mutations in the retinoblastoma-related gene Rb2/p130 in primary nasopharyngeal carcinoma
-
CLAUDIO PP, HOWARD CM, FU Y et al: Mutations in the retinoblastoma- related gene Rb2/p130 in primary nasopharyngeal carcinoma. CancerRes. (2000) 60:8-12.
-
(2000)
CancerRes.
, vol.60
, pp. 8-12
-
-
Claudio, P.P.1
Howard, C.M.2
Y, F.U.3
-
24
-
-
0027326586
-
The tumor suppressor genes
-
LEVINE AJ: The tumor suppressor genes. Ann. Rev Biochem. (1993) 62:623-651.
-
(1993)
Ann. Rev Biochem.
, vol.62
, pp. 623-651
-
-
Levine, A.J.1
-
25
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
WEINBERG RA: The retinoblastoma protein and cell cycle control. Cell (1995) 81:323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
27
-
-
12044258811
-
Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain
-
MAYOL X, GRANA X, BALDI A, SANG N, HU Q, GIORDANO A: Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. Oncogene (1993) 8:2561-2566.
-
(1993)
Oncogene
, vol.8
, pp. 2561-2566
-
-
Mayol, X.1
Grana, X.2
Baldi, A.3
Sang, N.4
Q, H.U.5
Giordano, A.6
-
28
-
-
0025785484
-
Molecular cloning, chromosomal mapping and expression of the cDNA for p107, a retinoblastoma gene product-related protein
-
EWEN ME, XING EW, LAWRENCE JB, LIVINSTON D: Molecular cloning, chromosomal mapping and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell (1991) 66:1155-1164.
-
(1991)
Cell
, vol.66
, pp. 1155-1164
-
-
Ewen, M.E.1
Xing, E.W.2
Lawrence, J.B.3
Livinston, D.4
-
29
-
-
0027142956
-
Isolation of the Rb-related p130 through its interaction with cdk2 and cyclins
-
HANNON GJ, DEMERICK D, BEACH D: Isolation of the Rb-related p130 through its interaction with cdk2 and cyclins. GenesDev. (1993) 7:2378-2391.
-
(1993)
GenesDev.
, vol.7
, pp. 2378-2391
-
-
Hannon, G.J.1
Demerick, D.2
Beach, D.3
-
30
-
-
0027135209
-
The adenovirus E1A-associated 130-kd protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and e in a temporally distinct manner
-
LI Y, GRAHAM C, LACY S, DUNCAN AMV, WHYTE P: The adenovirus E1A-associated 130-kd protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E in a temporally distinct manner. Genes Dev. (1993) 7:2366-2377.
-
(1993)
Genes Dev.
, vol.7
, pp. 2366-2377
-
-
Y, L.I.1
Graham, C.2
Lacy, S.3
Amv, D.4
Whyte, P.5
-
31
-
-
2642601106
-
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
-
LEE JO, RUSSO AA, PAVLETICH NP: Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature (1998) 391:859-865
-
(1998)
Nature
, vol.391
, pp. 859-865
-
-
Lee, J.O.1
Russo, A.A.2
Pavletich, N.P.3
-
32
-
-
0031016121
-
Rb kinase and Rb-bindingproteins: New point of view
-
TAYA Y: Rb kinase and Rb-bindingproteins: new point of view. Trends Biol Sci. (1997) 21:14-17.
-
(1997)
Trends Biol Sci.
, vol.21
, pp. 14-17
-
-
Taya, Y.1
-
33
-
-
0002939853
-
The intrinsic cell cycle: From yeast to mammal
-
Stein GS, Baserga R, Giordano A, Denhardt DT (Eds.) Wiley-Liss, New York, USA
-
PURI PL, MACLACHLAN TK, LEVRERO M, GIORDANO A: The intrinsic cell cycle: from yeast to mammal. In: The Molecular Basis of Cell Cycle and Growth Control. Stein GS, Baserga R, Giordano A, Denhardt DT (Eds.), Wiley-Liss, New York, USA (1999):15-79.
-
(1999)
The Molecular Basis of Cell Cycle and Growth Control
, pp. 15-79
-
-
Puri, P.L.1
MacLachlan, T.K.2
Levrero, M.3
Giordano, A.4
-
34
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
DYSON N: The regulation of E2F by pRB-family proteins. Genes Dev. (1998) 12:2245-2262.
-
(1998)
Genes Dev.
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
35
-
-
0032549001
-
Rb interacts with histone deacetylase to repress transcription
-
LUO RX, POSTIGO AA, DEAN DC: Rb interacts with histone deacetylase to repress transcription. Cell (1998) 92:463-473.
-
(1998)
Cell
, vol.92
, pp. 463-473
-
-
Luo, R.X.1
Postigo, A.A.2
Dean, D.C.3
-
36
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
BREHM A, MISKAEA, MCCANCEDJ et al: Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (1998) 391:597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miskae, A.2
McCanced, J.3
-
37
-
-
0032533860
-
The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter
-
STIEGLER P, DE LUCA A, BAGELLA L, GIORDANO A: The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter. Cancer Res. (1998) 58:5049-5052.
-
(1998)
Cancer Res.
, vol.58
, pp. 5049-5052
-
-
Stiegler, P.1
De Luca, A.2
Bagella, L.3
Giordano, A.4
-
38
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting histone deacetylase
-
MAGNAGHI-JAULIN L, GROISMAN R, NAGUIBNEBA I et al: Retinoblastoma protein represses transcription by recruiting histone deacetylase. Nature (1998) 391:601-604.
-
(1998)
Nature
, vol.391
, pp. 601-604
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneba, I.3
-
39
-
-
0031862730
-
Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): Contribution from the RB C pocket
-
WHITAKER LL, SU H, BASKARAN R, KNUDSEN ES, WANG JY: Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket. Mol Cell. Biol. (1998) 18:4032-4042.
-
(1998)
Mol Cell. Biol.
, vol.18
, pp. 4032-4042
-
-
Whitaker, L.L.1
H, S.U.2
Baskaran, R.3
Knudsen, E.S.4
Wang, J.Y.5
-
40
-
-
0025273737
-
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations
-
HU Q, DYSON N, HARLOW E: The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations. EMBOJ. (1990) 9:1147-1155.
-
(1990)
EMBOJ.
, vol.9
, pp. 1147-1155
-
-
Q, H.U.1
Dyson, N.2
Harlow, E.3
-
41
-
-
0025340056
-
Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen
-
HUANG S, WANG N-P, TSENG BY, LEE WH, LEE EH-HP: Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen. EMBO J. (1990) 9:1815-1822.
-
(1990)
EMBO J.
, vol.9
, pp. 1815-1822
-
-
Huang, S.1
Wang, N.-P.2
Tseng, B.Y.3
Lee, W.H.4
Eh-Hp, L.5
-
42
-
-
0030764940
-
Aunique domain of pRb2/p130 acts as inhibitor of cdk2 kinase activity.J
-
DE LUCA A, MACLACHLAN TK, BAGELLA L et al: Aunique domain of pRb2/p130 acts as inhibitor of cdk2 kinase activity. J. Biol Chem. (1997) 272:20971-20974.
-
(1997)
Biol Chem.
, vol.272
, pp. 20971-20974
-
-
De Luca, A.1
MacLachlan, T.K.2
Bagella, L.3
-
43
-
-
0030992490
-
RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2
-
CHU WM, WANG Z, ROEDER RG, SCHMID CW J: RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. J. Biol Chem. (1997) 272:14755-14761.
-
(1997)
J. Biol Chem.
, vol.272
, pp. 14755-14761
-
-
Chu, W.M.1
Wang, Z.2
Roeder, R.G.3
Schmid, C.W.J.4
-
44
-
-
0029901988
-
Repression of RNA polymerase III transcription by the retinoblastoma protein
-
WHITE RJ, TROUCHE D, MARTIN K, JACKSON SP, KOUZARIDES T: Repression of RNA polymerase III transcription by the retinoblastoma protein. Nature (1996) 382:88-90.
-
(1996)
Nature
, vol.382
, pp. 88-90
-
-
White, R.J.1
Trouche, D.2
Martin, K.3
Jackson, S.P.4
Kouzarides, T.5
-
45
-
-
0032973316
-
RNA polymerase III transcription Factor IIIB is a target for repression by pocket proteins p107 and p130
-
SUTCLIFFE JE, CAIRNS CA, MCLEES A et al: RNA polymerase III transcription Factor IIIB is a target for repression by pocket proteins p107 and p130. Mol Cell. Biol (1999) 19:4255-4261.
-
(1999)
Mol Cell. Biol
, vol.19
, pp. 4255-4261
-
-
Sutcliffe, J.E.1
Cairns, C.A.2
McLees, A.3
-
47
-
-
0028919678
-
In vivo association of E2F and DP family proteins
-
WU CL, ZUKERBERG LR, NGWU C, HARLOW E, LEES JA: In vivo association of E2F and DP family proteins. Mol Cell. Biol (1995) 15:2536-2546.
-
(1995)
Mol Cell. Biol
, vol.15
, pp. 2536-2546
-
-
Cl, W.U.1
Zukerberg, L.R.2
Ngwu, C.3
Harlow, E.4
Lees, J.A.5
-
49
-
-
0026440512
-
Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding
-
QIAN Y, LUCKEY C, HORTON L, ESSER M, TEMPLETON DJ: Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding. Mol. Cell. Biol. (1992) 12:5363-5372.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5363-5372
-
-
Qian, Y.1
Luckey, C.2
Horton, L.3
Esser, M.4
Templeton, D.J.5
-
50
-
-
0026648086
-
Identification of a growth suppressor domain within the retinoblastoma gene product
-
QUIN XQ, CHITTENDEN T, LIVINGSTON D, KAELIN WG: Identification of a growth suppressor domain within the retinoblastoma gene product. Genes Dev. (1992) 6:953-964.
-
(1992)
Genes Dev.
, vol.6
, pp. 953-964
-
-
Quin, X.Q.1
Chittenden, T.2
Livingston, D.3
Kaelin, W.G.4
-
51
-
-
0027212380
-
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factors are necessary for E2 promoter repression and pRb-mediated growth suppression
-
HIEBERT SW: Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factors are necessary for E2 promoter repression and pRb-mediated growth suppression. Mol. Cell. Biol. (1993) 13:3384-3391.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3384-3391
-
-
Hiebert, S.W.1
-
52
-
-
0025770719
-
Domains of the adenovirus E1A protein that are required for oncogenic activity are also required for dissociation of E2F transcription factor complex
-
RAYCHADHURY P, BAGCHI S, DEVOTO SH et al.: Domains of the adenovirus E1A protein that are required for oncogenic activity are also required for dissociation of E2F transcription factor complex. Genes Dev. (1991) 5:1200-1211.
-
(1991)
Genes Dev.
, vol.5
, pp. 1200-1211
-
-
Raychadhury, P.1
Bagchi, S.2
Devoto, S.H.3
-
53
-
-
0025009110
-
A single amino acid substitution results in a retinoblas-toma protein defective in phosphorylation and oncoprotein binding
-
KAYE FJ, KRATZKE RA, GERSTER JL, HOROWITZ JM: A single amino acid substitution results in a retinoblas-toma protein defective in phosphorylation and oncoprotein binding. Proc. Natl. Acad. Sci. USA (1990) 87:6922-6926.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6922-6926
-
-
Kaye, F.J.1
Kratzke, R.A.2
Gerster, J.L.3
Horowitz, J.M.4
-
54
-
-
0024500043
-
Point mutational inactivation of the retinoblastoma antion-cogene
-
HOROWITZ JM, YANDELL DW, PARK SH et al.: Point mutational inactivation of the retinoblastoma antion-cogene. Science (1989) 243:937-940.
-
(1989)
Science
, vol.243
, pp. 937-940
-
-
Horowitz, J.M.1
Yandell, D.W.2
Park, S.H.3
-
55
-
-
0025734783
-
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
-
CHITTEDEN T, LIVINGSTON DM, KAELIN WG: The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell (1991) 65:1071-1082.
-
(1991)
Cell
, vol.65
, pp. 1071-1082
-
-
Chitteden, T.1
Livingston, D.M.2
Kaelin, W.G.3
-
56
-
-
0026537277
-
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F
-
HIEBERT SW, CHELLAPPAN SP, HOROWITS JM, NEVINS JR: The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. (1992) 6:177-185.
-
(1992)
Genes Dev.
, vol.6
, pp. 177-185
-
-
Hiebert, S.W.1
Chellappan, S.P.2
Horowits, J.M.3
Nevins, J.R.4
-
57
-
-
11944270727
-
Introduction to the E2F family: Protein structure and gene regulation
-
SLANSKY JE, FARNHAM PJ: Introduction to the E2F family: protein structure and gene regulation. Curr. Top. Microbiol. Immunol. (1996) 208:1-30.
-
(1996)
Curr. Top. Microbiol. Immunol.
, vol.208
, pp. 1-30
-
-
Slansky, J.E.1
Farnham, P.J.2
-
58
-
-
0034058076
-
Gene therapy models. The Rb2/p130 gene: The latest weapon in the war against lung cancer?
-
CLAUDIO PP, CAPUTI M, GIORDANO A: Gene therapy models. The Rb2/p130 gene: the latest weapon in the war against lung cancer? Clin. Canc. Res. (2000) 6:754-764.
-
(2000)
Clin. Canc. Res.
, vol.6
, pp. 754-764
-
-
Claudio, P.P.1
Caputi, M.2
Giordano, A.3
-
59
-
-
0028902381
-
Functional interaction between E2F-4 and p130: Evidence for distinct mechanisms underlying growth suppressor by different retinoblastoma protein family members
-
VAIRO G, LIVINGSTON DM, GINSBERG D: Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppressor by different retinoblastoma protein family members. Genes Dev. (1995) 9:869-881.
-
(1995)
Genes Dev.
, vol.9
, pp. 869-881
-
-
Vairo, G.1
Livingston, D.M.2
Ginsberg, D.3
-
60
-
-
0028148858
-
E2F4, a new member of the E2F transcription factor family, interacts with p107
-
GINSBERG D, VAIRO G, CHITTENDEN T et al.: E2F4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev. (1994) 8:2665-2679.
-
(1994)
Genes Dev.
, vol.8
, pp. 2665-2679
-
-
Ginsberg, D.1
Vairo, G.2
Chittenden, T.3
-
61
-
-
0029978325
-
E2F4 switches from p130 top107 and pRb in responseto cell cycle reentry
-
MOBERG K, STARTS MA, LEES JA: E2F4 switches from p130 top107 and pRb in responseto cell cycle reentry. Mol. Cell. Biol. (1996) 16:1436-1449.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1436-1449
-
-
Moberg, K.1
Starts, M.A.2
Lees, J.A.3
-
62
-
-
0029035124
-
E2F5, a new E2F family member that interacts with p130 in vivo
-
HIJMANS EN, VOORHOEVE PM, BEIJERSBERGEN RL, VAN 'T VEER LJ, BERNARDS R: E2F5, a new E2F family member that interacts with p130 in vivo. Mol. Cell. Biol. (1995) 15:3082-3089.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3082-3089
-
-
Hijmans, E.N.1
Voorhoeve, P.M.2
Beijersbergen, R.L.3
Van 'T Veer, L.J.4
Bernards, R.5
-
64
-
-
0029912789
-
Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal
-
. DE LA LUNA S, BURDEN MJ, LEE C-W, LA THANGUE NB: Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. J. Cell Sci. (1996) 109:2443-2452.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 2443-2452
-
-
De La Luna, S.1
Burden, M.J.2
Lee, C.-W.3
La Thangue, N.B.4
-
65
-
-
0029991715
-
Nuclear localization of DP and E2F transcription factors by heterodimeric patterns and retinoblastoma protein family members
-
MAGAE J, WU C-L, ILLENYE S, HARLOW E, HEINTZ NH: Nuclear localization of DP and E2F transcription factors by heterodimeric patterns and retinoblastoma protein family members. J. Cell Sci. (1996) 109:1717-1726.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1717-1726
-
-
Magae, J.1
Wu, C.-L.2
Illenye, S.3
Harlow, E.4
Heintz, N.H.5
-
66
-
-
0032053727
-
Regulation of E2F4 mitogenic activity during terminal differentiation by its heterodimerization partners for nuclear translocation
-
PURI PL, CIMINO L, FULCO M et al: Regulation of E2F4 mitogenic activity during terminal differentiation by its heterodimerization partners for nuclear translocation. Cancer Res. (1998) 58:1325-1331.
-
(1998)
Cancer Res.
, vol.58
, pp. 1325-1331
-
-
Puri, P.L.1
Cimino, L.2
Fulco, M.3
-
67
-
-
0027140404
-
Cell cycle specific association of E2Fwith the p130 E1A-binding protein
-
COBRINIK D, WHYTE P, PEEPER DS, JACKS T, WEINBERG RA: Cell cycle specific association of E2Fwith the p130 E1A-binding protein. Genes Dev. (1993) 7:2392-2404.
-
(1993)
Genes Dev.
, vol.7
, pp. 2392-2404
-
-
Cobrinik, D.1
Whyte, P.2
Peeper, D.S.3
Jacks, T.4
Weinberg, R.A.5
-
68
-
-
0028791305
-
Regulation of E2F1 gene expression by p130 (Rb2) and D-type cyclin kinase activity
-
JOHNSON DG: Regulation of E2F1 gene expression by p130 (Rb2) and D-type cyclin kinase activity. Oncogene (1995) 11:1685-1692.
-
(1995)
Oncogene
, vol.11
, pp. 1685-1692
-
-
Johnson, D.G.1
-
69
-
-
0029054133
-
Differential role of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins
-
ZHU L,XIEE, CHANG LS: Differential role of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins. Mol. Cell. Biol (1995) 15:3552-3562.
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 3552-3562
-
-
Lxiee, Z.1
Chang, L.S.2
-
70
-
-
0028082795
-
The E2F transcription factor: Role of the cell cycle regulation and differentiation
-
CHELLAPPAN SP: The E2F transcription factor: role of the cell cycle regulation and differentiation. Mol. Cell. Differ. (1994) 2:201-220.
-
(1994)
Mol. Cell. Differ.
, vol.2
, pp. 201-220
-
-
Chellappan, S.P.1
-
72
-
-
0028360766
-
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
-
SINGH P, WONG S, HONG W: Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBOJ. (1994) 13:3329-3338.
-
(1994)
EMBO J.
, vol.13
, pp. 3329-3338
-
-
Singh, P.1
Wong, S.2
Hong, W.3
-
73
-
-
0028945789
-
Multiple members of the E2Ftranscription factor family are the products of oncogenes
-
XU G, LIVINGSTON DM, KREK W: Multiple members of the E2Ftranscription factor family are the products of oncogenes. Proc.Natl. Acad. Sci. USA (1995) 92:1357-1361.
-
(1995)
Proc.Natl. Acad. Sci. USA
, vol.92
, pp. 1357-1361
-
-
G, X.U.1
Livingston, D.M.2
Krek, W.3
-
74
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
YAMASAKI L, JACKS T, BRONSON R et al: Tumor induction and tissue atrophy in mice lacking E2F-1. Cell (1996) 85:537-548.
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
-
75
-
-
0032510342
-
Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
-
PIERCE AM, FISHER SM, CONTI CJ, JOHNSON DG: Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development. Oncogene (1998) 16:1267-1276.
-
(1998)
Oncogene
, vol.16
, pp. 1267-1276
-
-
Pierce, A.M.1
Fisher, S.M.2
Conti, C.J.3
Johnson, D.G.4
-
77
-
-
0027408679
-
DNAtumor virus transformingproteins and the cell cycle
-
MORAN E: DNAtumor virus transformingproteins and the cell cycle. Curr. Opin. Genet. Dev. (1993) 3:63-70.
-
(1993)
Curr. Opin. Genet. Dev.
, vol.3
, pp. 63-70
-
-
Moran, E.1
-
78
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
DECAPRIO JA, LUDLOW JW, FIGGE J et al.: SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell (1988) 54:275-283.
-
(1988)
Cell
, vol.54
, pp. 275-283
-
-
Decaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
-
79
-
-
0024535228
-
The human papilloma virus-16 E7 oncoprotein is able to bindtothe retinoblastoma geneproduct
-
DYSON N, HOWLEY PM, MUENGER K, HARLOW E: The human papilloma virus-16 E7 oncoprotein is able to bindtothe retinoblastoma geneproduct. Science (1989) 243:934-937.
-
(1989)
Science
, vol.243
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Muenger, K.3
Harlow, E.4
-
80
-
-
0023914010
-
Association between an oncogene and an antioncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
-
WHYTE P, BUCKOVICH KJ, HOROWITZ JMet al.: Association between an oncogene and an antioncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature (1988) 334:124-127.
-
(1988)
Nature
, vol.334
, pp. 124-127
-
-
Whyte, P.1
Buckovich, K.J.2
Horowitz, J.M.3
-
81
-
-
0024968181
-
HARLOWE: Cellular targets for transformation by the adenovirus E1A proteins
-
WHYTEP,WILLIAMSON NM, HARLOWE: Cellular targets for transformation by the adenovirus E1A proteins. Cell (1989) 56:67-75.
-
(1989)
Cell
, vol.56
, pp. 67-75
-
-
Whytepwilliamson, N.M.1
-
82
-
-
0029989279
-
Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107
-
STUBDAL H, ZALVIDE J, DECAPRIO JA: Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107. J. Virol. (1996) 70:2781-2788.
-
(1996)
J. Virol.
, vol.70
, pp. 2781-2788
-
-
Stubdal, H.1
Zalvide, J.2
Decaprio, J.A.3
-
83
-
-
0025994793
-
Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A
-
GIORDANO A, LEE JH, SCHEPPLER JA et al.: Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A. Science (1991) 253:1271-1275.
-
(1991)
Science
, vol.253
, pp. 1271-1275
-
-
Giordano, A.1
Lee, J.H.2
Scheppler, J.A.3
-
84
-
-
0028177401
-
P53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein
-
SLEBO RJ, LEE MH, PLUNKETT BS et al.: p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc. Natl. Acad. Sci. USA (1994) 91:5320-5324.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5320-5324
-
-
Slebo, R.J.1
Lee, M.H.2
Plunkett, B.S.3
-
85
-
-
0030794278
-
Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen
-
STUBDAL H, ZALVIDE J, CAMPBEL KS et al.: Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol. Cell. Biol. (1997) 17:4979-4990.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4979-4990
-
-
Stubdal, H.1
Zalvide, J.2
Campbel, K.S.3
-
86
-
-
0025336768
-
Identification of the region of simian virus 40 large T antigen required for cell transformation
-
CHEN S, PAUCHA E: Identification of the region of simian virus 40 large T antigen required for cell transformation. J. Virol. (1990) 64:3350-3357.
-
(1990)
J. Virol.
, vol.64
, pp. 3350-3357
-
-
Chen, S.1
Paucha, E.2
-
87
-
-
0024515741
-
Binding of the Rb1 protein to E1A products is required for adenovirus transformation
-
EGAN C, BAYLEY ST, BRANTON PE: Binding of the Rb1 protein to E1A products is required for adenovirus transformation. Oncogene (1989) 4:383-388.
-
(1989)
Oncogene
, vol.4
, pp. 383-388
-
-
Egan, C.1
Bayley, S.T.2
Branton, P.E.3
-
88
-
-
0022800182
-
Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes
-
MORAN E, ZERLER B, HARRISON TM, MATHEWS MB: Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes. Mol. Cell. Biol. (1986) 6:3470-3480.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 3470-3480
-
-
Moran, E.1
Zerler, B.2
Harrison, T.M.3
Mathews, M.B.4
-
89
-
-
0023925848
-
Two regions of the adenovirus early reaction 1A protein are required for transformation
-
WHYTE P, RULEY HE, HARLOW E: Two regions of the adenovirus early reaction 1A protein are required for transformation. J. Virol. (1988) 62:257-265.
-
(1988)
J. Virol.
, vol.62
, pp. 257-265
-
-
Whyte, P.1
Ruley, H.E.2
Harlow, E.3
-
90
-
-
0025024111
-
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: A novel mechanism for E1A trans-activation
-
BAGCHI S, RAYCHAUDHURI P, NEVINS JR: Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. Cell (1990) 62:659-669.
-
(1990)
Cell
, vol.62
, pp. 659-669
-
-
Bagchi, S.1
Raychaudhuri, P.2
Nevins, J.R.3
-
91
-
-
0026526437
-
E2F: A link between Rb tumor suppressor protein and viral oncoproteins
-
NEVINS JR: E2F: a link between Rb tumor suppressor protein and viral oncoproteins. Science (1992) 258:424-429.
-
(1992)
Science
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
92
-
-
0025287564
-
Definition of the minimal simian virus 40 large T antigen and adenovirus E1A-binding domain in the retinoblatoma gene product
-
KAELIN WG, EWEN ME, LIVINGSTON DM: Definition of the minimal simian virus 40 large T antigen and adenovirus E1A-binding domain in the retinoblatoma gene product. Mol. Cell. Biol (1990) 10:3761-3769.
-
(1990)
Mol. Cell. Biol
, vol.10
, pp. 3761-3769
-
-
Kaelin, W.G.1
Ewen, M.E.2
Livingston, D.M.3
-
93
-
-
0025949412
-
Nuclear targeting sequences: A consensus?
-
DINGWALL C, LASKEY RA: Nuclear targeting sequences: a consensus? Trends Biol. Sci. (1991) 16:478-481.
-
(1991)
Trends Biol. Sci.
, vol.16
, pp. 478-481
-
-
Dingwall, C.1
Laskey, R.A.2
-
94
-
-
0027214095
-
A bipartite nuclear localization signal in the retinoblas toma gene product and its importance for biological activity
-
ZACKSENHAUS E, BREMNER R, PHILLIPS RA, GALLIE BL: A bipartite nuclear localization signal in the retinoblas toma gene product and its importance for biological activity. Mol. Cell. Biol. (1993) 13:4588-4599.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4588-4599
-
-
Zacksenhaus, E.1
Bremner, R.2
Phillips, R.A.3
Gallie, B.L.4
-
95
-
-
0029917843
-
Translocation of the retinoblastoma gene product during mitosis
-
THOMAS RC, EDWARS MJ, MARKS R: Translocation of the retinoblastoma gene product during mitosis. Exp. Cell Res. (1996) 223:227-232.
-
(1996)
Exp. Cell Res.
, vol.223
, pp. 227-232
-
-
Thomas, R.C.1
Edwars, M.J.2
Marks, R.3
-
96
-
-
0030798245
-
Histone acetylation in chromatin structure and transcription
-
GRUMSTEIN M: Histone acetylation in chromatin structure and transcription. Nature (1997) 389:349-352.
-
(1997)
Nature
, vol.389
, pp. 349-352
-
-
Grumstein, M.1
-
97
-
-
1842413645
-
P130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
-
WOO MS-A, SANCHEZ I, DYNLACHT BD: p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity. Mol. Cell. Biol. (1997) 17:3566-3579.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3566-3579
-
-
Ms-A, W.1
Sanchez, I.2
Dynlacht, B.D.3
-
98
-
-
0025932608
-
Adenovirus E1A is associated with a serine/threonine protein kinase
-
HERRMANN CH, SU LK, HARLOW E: Adenovirus E1A is associated with a serine/threonine protein kinase. J. Virol. (1991) 65:5848-5859.
-
(1991)
J. Virol.
, vol.65
, pp. 5848-5859
-
-
Herrmann, C.H.1
Lk, S.U.2
Harlow, E.3
-
99
-
-
0029924241
-
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites
-
KNUDSEN ES, WANG JYJ: Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites. J. Biol. Chem. (1996) 271:8313-8320.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8313-8320
-
-
Knudsen, E.S.1
Jyj, W.2
-
100
-
-
0026530730
-
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
-
SHIRODKAR S, EWEN M, DECAPRIO JA et al.: The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 66:157-166.
-
(1992)
Cell
, vol.66
, pp. 157-166
-
-
Shirodkar, S.1
Ewen, M.2
Decaprio, J.A.3
-
101
-
-
0028881866
-
The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated
-
BALDI A, DE LUCA A, CLAUDIO PP et al.: The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cell cycle regulated. J. Cell. Biochem. (1995) 59:402-408.
-
(1995)
J. Cell. Biochem.
, vol.59
, pp. 402-408
-
-
Baldi, A.1
De Luca, A.2
Claudio, P.P.3
-
102
-
-
0032546322
-
The retinoblastoma protein is essential for cyclin A repression in quiescent cells
-
PHILLIPS A, HUET X, PLET A et al: The retinoblastoma protein is essential for cyclin A repression in quiescent cells. Oncogene (1998) 16:1373-1381.
-
(1998)
Oncogene
, vol.16
, pp. 1373-1381
-
-
Phillips, A.1
Huet, X.2
Plet, A.3
-
103
-
-
2642663515
-
The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts.J
-
DONG F, CRESS WD JR, AGRAWAL D, PLEDGER WJ: The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts. J. Biol Chem. (1998) 273:6190-6195.
-
(1998)
Biol Chem.
, vol.273
, pp. 6190-6195
-
-
Dong, F.1
Cress Jr., W.D.2
Agrawal, D.3
Pledger, W.J.4
-
104
-
-
0033573310
-
Interaction between the pRb2/p130 C-terminal domain and N-terminal portion of cyclin D3.J
-
BONETTO F, FANCIULLI M, BATTISTA T et al: Interaction between the pRb2/p130 C-terminal domain and N-terminal portion of cyclin D3. J. Cell Biochem. (1999) 75:698-709.
-
(1999)
Cell Biochem.
, vol.75
, pp. 698-709
-
-
Bonetto, F.1
Fanciulli, M.2
Battista, T.3
-
105
-
-
0027204555
-
Physical interac tion of retinoblastoma protein with human D cyclin
-
DOWDY SF, HINDS PW, LOUIS K et al: Physical interac tion of retinoblastoma protein with human D cyclin. Cell(1993) 73:499-511.
-
(1993)
Cell
, vol.73
, pp. 499-511
-
-
Dowdy, S.F.1
Hinds, P.W.2
Louis, K.3
-
106
-
-
0029962144
-
Functional analysis of pRb2/p130 interaction with cyclins
-
CLAUDIO PP, DE LUCA A, HOWARD CM et al: Functional analysis of pRb2/p130 interaction with cyclins. Cancer Res. (1996) 56:2003-2008.
-
(1996)
Cancer Res.
, vol.56
, pp. 2003-2008
-
-
Claudio, P.P.1
De Luca, A.2
Howard, C.M.3
-
107
-
-
0030561571
-
The retinoblastoma protein pathway and the restriction point
-
BARTEK J, BARTKOVA J, LUKAS J: The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. (1996) 8:805-814.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 805-814
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
108
-
-
0029281412
-
The retinoblastoma protein and its relatives
-
WHYTEP:The retinoblastoma protein and its relatives. Semin. Cancer. Biol. (1995) 6:83-90.
-
(1995)
Semin. Cancer. Biol.
, vol.6
, pp. 83-90
-
-
Whyte, P.1
-
109
-
-
0034657273
-
Inducible pRb2/p130 expression and growth-suppressive mechanisms: Evidence of a pRb2/p130 p27kip1 and cyclin Enegative feedback regulatory loop
-
HOWARD CM, CLAUDIO PP, DE LUCA A et al: Inducible pRb2/p130 expression and growth-suppressive mechanisms: evidence of a pRb2/p130, p27kip1 and cyclin Enegative feedback regulatory loop. Cancer Res. (2000) 60:2737-2744.
-
(2000)
Cancer Res.
, vol.60
, pp. 2737-2744
-
-
Howard, C.M.1
Claudio, P.P.2
De Luca, A.3
-
110
-
-
0030678627
-
Role of the retinoblas toma protein in the pathogenesis of human cancer
-
SELLERS WR, KAELIN WG, JR.: Role of the retinoblas toma protein in the pathogenesis of human cancer. J. Clin. Oncol. (1997) 15:3301-3312.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 3301-3312
-
-
Sellers, W.R.1
Kaelin Jr., W.G.2
-
111
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
SERRANO M, LEE HW, CHIN L et al: Role of the INK4a locus in tumor suppression and cell mortality. Cell (1996) 85:27-37.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.W.2
Chin, L.3
-
112
-
-
0028978183
-
Mice lacking p21 CIP/WAF1 undergo normal development, but are defective in the G1 checkpoint control
-
DENG C, ZHANG P, HARPER P et al.: Mice lacking p21 CIP/WAF1 undergo normal development, but are defective in the G1 checkpoint control. Cell (1995) 82:675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, P.3
-
113
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism tumorigenesis and female sterility in p27Kip1-deficent mice
-
FERO ML, RIVKIN M, TASCH M et al: A syndrome of multiorgan hyperplasia with features of gigantism tumorigenesis and female sterility in p27Kip1-deficent mice. Cell (1996) 85:733-744.
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
-
114
-
-
0030010591
-
Kip1display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors
-
NAKAYAMA K, ISHIDA N, SHIRANE M et al.: Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors. Cell (1996) 85:707-720.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
-
115
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
-
HARBOUR JW, LUO RX, DEI SANTI A, POSTIGO AA, DEAN DC: Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell (1999) 98:859-869.
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Dei Santi, A.3
Postigo, A.A.4
Dean, D.C.5
-
116
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
SHERR CJ, ROBERTS JM: Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. (1995) 9:1149-1463.
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1463
-
-
Sherr, C.J.1
Roberts, J.M.2
-
117
-
-
0028983384
-
P107 uses a p21CIP-related domain to bind cyclin/cdk2 and regulate interactions with E2F
-
ZHU L, HARLOW E, DYNLACHT BD: p107 uses a p21CIP-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev. (1995) 9:1740-1752.
-
(1995)
Genes Dev.
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
-
118
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
LUNDBERG AS, WEINBERG RA: Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol. (1998) 18:753-761.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 753-761
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
120
-
-
0032508529
-
P130, p107 and pRb are differentially regulated in proliferating cells and during cell cycle arrest by "/-interferon
-
THOMAS NSB, PIZZEY AR, TIWARI S, WILLIAMS CD, YANG J: p130, p107 and pRb are differentially regulated in proliferating cells and during cell cycle arrest by "/-interferon. J. Biol. Chem. (1998) 273: 23659-23667.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23659-23667
-
-
Nsb, T.1
Pizzey, A.R.2
Tiwari, S.3
Williams, C.D.4
Yang, J.5
-
121
-
-
0031815596
-
Toward an understanding of the functional complexity of the E2F and retinoblastoma families
-
NEVINS JR: Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ. (1998) 9:585-593.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 585-593
-
-
Nevins, J.R.1
-
122
-
-
0027250860
-
E2F1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product
-
FLEMINGTON EK, SPECK SH, KAELIN WG, JR.: E2F1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product. Proc. Natl. Acad. Sci. USA (1993) 90:6914-6918.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6914-6918
-
-
Flemington, E.K.1
Speck, S.H.2
Kaelin Jr., W.G.3
-
123
-
-
0027382336
-
Inhibition of E2F1 transactivation by direct binding of the retinoblastoma protein
-
HELIN K, HARLOW E, FATTAEY A: Inhibition of E2F1 transactivation by direct binding of the retinoblastoma protein. Mol. Cell. Biol. (1993) 13:6501-6508.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6501-6508
-
-
Helin, K.1
Harlow, E.2
Fattaey, A.3
-
124
-
-
0029612231
-
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
-
SELLERS WR, RODGERS JW, KAELIN WG, JR.: A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl. Acad. Sci. USA (1995) 92:11544-11548.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11544-11548
-
-
Sellers, W.R.1
Rodgers, J.W.2
Kaelin Jr., W.G.3
-
125
-
-
0033786378
-
Rb function in cell-cycle regulation and apoptosis
-
HARBOUR JW, DEAN DC: Rb function in cell-cycle regulation and apoptosis. Nature Cell. Biol. (2000) 2:65-67.
-
(2000)
Nature Cell. Biol.
, vol.2
, pp. 65-67
-
-
Harbour, J.W.1
Dean, D.C.2
-
126
-
-
0033783177
-
Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators
-
MORRIS L, ALLEN KE, LA THANGUE NB: Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators. Nature Cell Biol. (2000) 2:232-239.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 232-239
-
-
Morris, L.1
Allen, K.E.2
La Thangue, N.B.3
-
127
-
-
0032232898
-
Big brothers are watching: The retinoblastoma family and growth control
-
Marcello-Colheiro (Ed.) Springer-Verlag, New York, USA
-
STIEGLER P, GIORDANO A: Big brothers are watching: the retinoblastoma family and growth control. In: Molecular and Subcellular Biology. Marcello-Colheiro (Ed.), Springer-Verlag, New York, USA (1998):24-42.
-
(1998)
Molecular and Subcellular Biology
, pp. 24-42
-
-
Stiegler, P.1
Giordano, A.2
-
128
-
-
0030678627
-
Role of the retinoblastoma protein in the pathogenesis of human cancer
-
SELLER WR, KAELIN WG: Role of the retinoblastoma protein in the pathogenesis of human cancer. J. Clin. Oncol. (1997)15:3301-3312.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 3301-3312
-
-
Seller, W.R.1
Kaelin, W.G.2
-
129
-
-
0032555151
-
Control of retinoblastoma protein-independent hematopoietic cell cycle by the pRB-related p130
-
HOSHIKAWA Y, MORI A, AMIMOTO K, IWABE K, HATAKEYAMA M: Control of retinoblastoma protein-independent hematopoietic cell cycle by the pRB-related p130. Proc. Natl. Acad. Sci. USA (1998) 95:8574-8579.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8574-8579
-
-
Hoshikawa, Y.1
Mori, A.2
Amimoto, K.3
Iwabe, K.4
Hatakeyama, M.5
-
130
-
-
0031983190
-
P130 is dispensable in peripheral T lymphocytes: Evidence for functional compensation by p107 and pRb
-
MULLIGAN GJ, WONG J, JACKS T: p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRb. Mol. Cell Biol. (1998) 18:206-220.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 206-220
-
-
Mulligan, G.J.1
Wong, J.2
Jacks, T.3
-
131
-
-
0026802989
-
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
-
HINDS PW, MITTNACHT S, DULIC V et al: Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell (1992) 70:993-1006.
-
(1992)
Cell
, vol.70
, pp. 993-1006
-
-
Hinds, P.W.1
Mittnacht, S.2
Dulic, V.3
-
132
-
-
0030970366
-
Identification of p130 domain mediating interactions with cyclin A/cdk2 and cyclin E/cdk2 complexes
-
LACY S, WHYTE P: Identification of p130 domain mediating interactions with cyclin A/cdk2 and cyclin E/cdk2 complexes. Oncogene (1997) 14:2395-2406.
-
(1997)
Oncogene
, vol.14
, pp. 2395-2406
-
-
Lacy, S.1
Whyte, P.2
-
133
-
-
0032494460
-
Retinoblastoma-related protein pRb2/p130 and suppression of tumor growth in vivo
-
HOWARD CM, CLAUDIO PP, GALLIA GL, GORDON J, GIORDANO A: Retinoblastoma-related protein pRb2/p130 and suppression of tumor growth in vivo. J. Nature Cancer Inst. (1998) 90:1415-1460.
-
(1998)
J. Nature Cancer Inst.
, vol.90
, pp. 1415-1460
-
-
Howard, C.M.1
Claudio, P.P.2
Gallia, G.L.3
Gordon, J.4
Giordano, A.5
-
134
-
-
0029026176
-
The pRb-related protein p107 contains two growth suppressor domains: Independent interaction with E2F and cyclin/cdk complexes
-
ZHU L, ENDERS G, LEES JA et al: The pRb-related protein p107 contains two growth suppressor domains: independent interaction with E2F and cyclin/cdk complexes. EMBOJ. (1995) 14:1904-1913.
-
(1995)
EMBOJ.
, vol.14
, pp. 1904-1913
-
-
Zhu, L.1
Enders, G.2
Lees, J.A.3
-
135
-
-
0030947095
-
Programmed cell death in animal development
-
JACOBSON MD, WEIL M, RAFF MC: Programmed cell death in animal development. Cell. (1997) 88:347-354.
-
(1997)
Cell.
, vol.88
, pp. 347-354
-
-
Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
-
137
-
-
0028842645
-
Cellular responses to DNA damage: Cell-cycle checkpoints, apoptosis and the roles of p53 and ATM
-
ENOCH T, NORBURY C: Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends Biochem. Sci. (1995) 20:426-430.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 426-430
-
-
Enoch, T.1
Norbury, C.2
-
138
-
-
0030941458
-
P53 the cellular gatekeeper for growth and division
-
LEVINE A: p53 the cellular gatekeeper for growth and division. Cell (1997) 88:323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.1
-
139
-
-
0031817711
-
PRb and cdks in apoptosis and cell cycle
-
KASTEN MM, GIORDANO A: pRb and cdks in apoptosis and cell cycle. Cell Death Differ. (1998) 5:132-140.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 132-140
-
-
Kasten, M.M.1
Giordano, A.2
-
140
-
-
0032159103
-
Mutation of E2F1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
-
TSAIKY, HU Y, MACLEOD KF, CROWLEY D, YAMASAKI L, JACKS T: Mutation of E2F1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell. (1998) 2:293-304.
-
(1998)
Mol. Cell.
, vol.2
, pp. 293-304
-
-
Tsaiky, H.U.Y.1
MacLeod, K.F.2
Crowley, D.3
Yamasaki, L.4
Jacks, T.5
-
141
-
-
0028861428
-
Inhibition of apoptosis by the retinoblastoma gene product
-
HAAS-KOGAN DA, KOGAN SC, LEVI D et al.: Inhibition of apoptosis by the retinoblastoma gene product. EMBOJ. (1995) 14:461-472.
-
(1995)
EMBOJ.
, vol.14
, pp. 461-472
-
-
Haas-Kogan, D.A.1
Kogan, S.C.2
Levi, D.3
-
142
-
-
0030031514
-
Cyclin D1 is an essential mediator of neuronal cell death
-
KRANENBURG O, VAN DER EB AJ, ZANTEMA A: Cyclin D1 is an essential mediator of neuronal cell death. EMBO J. (1996) 15:46-54.
-
(1996)
EMBO J.
, vol.15
, pp. 46-54
-
-
Kranenburg, O.1
Van Der, E.B.A.J.2
Zantema, A.3
-
143
-
-
10244227982
-
kip1, inhibits growth and enhances apoptosis
-
HAN EK, BEGEMANN M, SGAMBATO A et al.: Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth and enhances apoptosis. Cell Growth Differ (1996) 7:699-710.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 699-710
-
-
Han, E.K.1
Begemann, M.2
Sgambato, A.3
-
144
-
-
0028924026
-
PITSLRE protein kinase activity is associated with apoptosis
-
LAHTI JM, XIANG J, HEATH LS, CAMPANA D, KIDD J: PITSLRE protein kinase activity is associated with apoptosis. Mol. Cell. Biol. (1995) 15:1-11.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1-11
-
-
Lahti, J.M.1
Xiang, J.2
Heath, L.S.3
Campana, D.4
Kidd, J.5
-
145
-
-
0029736909
-
Targeted disruption of p107: Functional overlap between p107 and Rb
-
LEE MH, WILLIAMS BO, MULLIGAN G et al: Targeted disruption of p107: functional overlap between p107 and Rb. GenesDev. (1996) 16:1621-1632.
-
(1996)
GenesDev.
, vol.16
, pp. 1621-1632
-
-
Lee, M.H.1
Williams, B.O.2
Mulligan, G.3
-
146
-
-
0031050236
-
Rb functions to inhibit apoptosis during myocyte differentiation
-
WANG J, GUO K, WILLS KN, WALSH K: Rb functions to inhibit apoptosis during myocyte differentiation. Cancer Res. (1997) 57:351-354.
-
(1997)
Cancer Res.
, vol.57
, pp. 351-354
-
-
Wang, J.1
Guo, K.2
Wills, K.N.3
Walsh, K.4
-
147
-
-
0034193425
-
The retinoblastoma-like protein p130 is involved in the determination of reserve cells in differentiating myoblasts
-
CARNAC G, FAJAS L, L'HONORE A et al.: The retinoblastoma-like protein p130 is involved in the determination of reserve cells in differentiating myoblasts. Curr. Biol. (2000) 10:543-546.
-
(2000)
Curr. Biol.
, vol.10
, pp. 543-546
-
-
Carnac, G.1
Fajas, L.2
L'Honore, A.3
-
148
-
-
0030861489
-
Differential expression of pRb2/p130 andp107 in normal human tissues and in primary lung cancer
-
BALDI A, ESPOSITO V, DE LUCA A et al.: Differential expression of pRb2/p130 andp107 in normal human tissues and in primary lung cancer. Clin. Cancer. Res. (1997) 3:1691-1697.
-
(1997)
Clin. Cancer. Res.
, vol.3
, pp. 1691-1697
-
-
Baldi, A.1
Esposito, V.2
De Luca, A.3
-
149
-
-
0031831681
-
The retinoblastoma gene family: Cousins with overlapping interests
-
MULLIGAN G, JACKS T: The retinoblastoma gene family: cousins with overlapping interests. Trends Genet. (1998) 14:223-229.
-
(1998)
Trends Genet.
, vol.14
, pp. 223-229
-
-
Mulligan, G.1
Jacks, T.2
-
150
-
-
0028131540
-
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
-
LEE EYHP, HU H, YUAN SSF et al: Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. (1994) 8:2008-2021.
-
(1994)
Genes Dev.
, vol.8
, pp. 2008-2021
-
-
Eyhp, L.1
H, H.U.2
Ssf, Y.3
-
151
-
-
0033559609
-
Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity
-
CALLAGHAN DA, DONG L, CALLAGHAN SM et al: Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity. Dev. Biol (1999) 207:257-270.
-
(1999)
Dev. Biol
, vol.207
, pp. 257-270
-
-
Callaghan, D.A.1
Dong, L.2
Callaghan, S.M.3
-
152
-
-
0032433267
-
Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene
-
LECOUTER JE, KABLAR B, WHYTE PF, YING C, RUDNICKI MA: Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. Development (1998) 23:4669-4679.
-
(1998)
Development
, vol.23
, pp. 4669-4679
-
-
Lecouter, J.E.1
Kablar, B.2
Whyte, P.F.3
Ying, C.4
Rudnicki, M.A.5
-
153
-
-
0033523881
-
Granulocytic differentiation of myeloid progenitor cells by p130, the retino-blastoma tumor suppressor homologue
-
MORI A, HIGASHI H, HOSHIKAWA Y, IMAMURA M, ASAKA M, HATAKEYAMA M: Granulocytic differentiation of myeloid progenitor cells by p130, the retino-blastoma tumor suppressor homologue. Oncogene (1999) 18:6209-6221.
-
(1999)
Oncogene
, vol.18
, pp. 6209-6221
-
-
Mori, A.1
Higashi, H.2
Hoshikawa, Y.3
Imamura, M.4
Asaka, M.5
Hatakeyama, M.6
-
154
-
-
0032189684
-
Tumor suppressor proteins as regulators of cell differentiation
-
LI ZR, HROMCHAK R, MULTIPALLI A, BLOCH A: Tumor suppressor proteins as regulators of cell differentiation. Cancer. Res. (1998) 58:4282-4287.
-
(1998)
Cancer. Res.
, vol.58
, pp. 4282-4287
-
-
Zr, L.I.1
Hromchak, R.2
Multipalli, A.3
Bloch, A.4
-
155
-
-
7344254104
-
The Rb-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation
-
RASCHELLA G, TANNO B, BONETTO F et al.: The Rb-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation. Cell. Death Differ (1998) 5:401-407.
-
(1998)
Cell. Death Differ
, vol.5
, pp. 401-407
-
-
Raschella, G.1
Tanno, B.2
Bonetto, F.3
-
156
-
-
0034023572
-
Domain-independent regulation of the Rb family by polyoma-virus large T antigen
-
SHENG Q, LOVE TM, SCHAFFHAUSEN BJ: Domain-independent regulation of the Rb family by polyoma-virus large T antigen. J. Virol. (2000) 74:5280-5290.
-
(2000)
J. Virol.
, vol.74
, pp. 5280-5290
-
-
Sheng, Q.1
Love, T.M.2
Schaffhausen, B.J.3
-
158
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumori-genesis
-
HANAHAN D, FOLKMAN J: Patterns and emerging mechanisms of the angiogenic switch during tumori-genesis. Cell (1996) 86:353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
159
-
-
0033107533
-
Collateral expressionof proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis
-
RAK J, MITSUHASHI Y, SHEEHAN C et al.: Collateral expressionof proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis. Neoplasia (1999) 1:23-30.
-
(1999)
Neoplasia
, vol.1
, pp. 23-30
-
-
Rak, J.1
Mitsuhashi, Y.2
Sheehan, C.3
-
160
-
-
0032912175
-
From cell cycle regulationtoangiogenesis: Dialogue between the basic and clinical sciences
-
STIEGLER P, LOTAN R, GIORDANO A: From cell cycle regulationtoangiogenesis: dialogue between the basic and clinical sciences. J. Cell. Physiol. (1999) 179:233-236.
-
(1999)
J. Cell. Physiol.
, vol.179
, pp. 233-236
-
-
Stiegler, P.1
Lotan, R.2
Giordano, A.3
-
161
-
-
0029797025
-
Regulation of tumor growth and metastasis by thrombospondin-1
-
ROBERTS DD: Regulation of tumor growth and metastasis by thrombospondin-1. FASEB J. (1996) 10:1183-1191.
-
(1996)
FASEB J.
, vol.10
, pp. 1183-1191
-
-
Roberts, D.D.1
-
162
-
-
0032552020
-
P53 induces angiogenesis restricted dormancy in mouse fibrosar-coma
-
HOLMGREN L, JACKSON G, ARBISER J: p53 induces angiogenesis restricted dormancy in mouse fibrosar-coma. Oncogene (1998) 17:819-824.
-
(1998)
Oncogene
, vol.17
, pp. 819-824
-
-
Holmgren, L.1
Jackson, G.2
Arbiser, J.3
-
163
-
-
0028060380
-
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
-
DAMERON KM, VOLPERT OV, TAINSKY MA, BOUCK N: Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science (1994) 265:1582-1584.
-
(1994)
Science
, vol.265
, pp. 1582-1584
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
Bouck, N.4
-
164
-
-
0027979819
-
Loss of thrombospondin transcriptional activity in nickel-transformed cells
-
SALNIKOW K, COSENTINO S, KLEIN C, COSTA M: Loss of thrombospondin transcriptional activity in nickel-transformed cells. Mol. Cell Biol. (1994) 14:851-858.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 851-858
-
-
Salnikow, K.1
Cosentino, S.2
Klein, C.3
Costa, M.4
-
165
-
-
0033178714
-
Restorationof wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
-
HARADA H, NAKAGAWAK,IWATA Set al.: Restorationof wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas. Cancer. Res. (1999) 59:3783-3789.
-
(1999)
Cancer. Res.
, vol.59
, pp. 3783-3789
-
-
Harada, H.1
Nakagawa, K.2
Iwata, S.3
-
167
-
-
0029921317
-
Genetic alterations of cyclins, cyclin-dependent kinases and Cdk inhibitors in human cancer
-
HALL M, PETERS G: Genetic alterations of cyclins, cyclin-dependent kinases and Cdk inhibitors in human cancer. Adv. Cancer Res. (1996) 68:67-108.
-
(1996)
Adv. Cancer Res.
, vol.68
, pp. 67-108
-
-
Hall, M.1
Peters, G.2
-
168
-
-
0027454445
-
Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas
-
KHATIB ZA, MATSUSHIME H, VALENTINE M, SHAPIRO DN, SHERR CJ, LOOK AT: Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res. (1993) 53:5535-5541.
-
(1993)
Cancer Res.
, vol.53
, pp. 5535-5541
-
-
Khatib, Z.A.1
Matsushime, H.2
Valentine, M.3
Shapiro, D.N.4
Sherr, C.J.5
Look, A.T.6
-
169
-
-
0028061974
-
CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines
-
HE J, ALLEN JR, COLLINS VP et al.: CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines. Cancer Res. (1994) 54:5804-5807.
-
(1994)
Cancer Res.
, vol.54
, pp. 5804-5807
-
-
J, H.E.1
Allen, J.R.2
Collins, V.P.3
-
170
-
-
0028978274
-
Ap16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
-
WOLFEL T, HAUER M, SCHNEIDER J et al: Ap16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science (1995) 269:1281-1214.
-
(1995)
Science
, vol.269
, pp. 1281-1214
-
-
Wolfel, T.1
Hauer, M.2
Schneider, J.3
-
171
-
-
0029052951
-
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
-
KOH J, ENDERS GH, DYNLACHT BD, HARLOW E: Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature (1995) 375:506-510.
-
(1995)
Nature
, vol.375
, pp. 506-510
-
-
Koh, J.1
Enders, G.H.2
Dynlacht, B.D.3
Harlow, E.4
-
172
-
-
0029054399
-
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
-
LUKAS J, PARRY D, AAGAARD L et al: Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (1995) 375:503-506.
-
(1995)
Nature
, vol.375
, pp. 503-506
-
-
Lukas, J.1
Parry, D.2
Aagaard, L.3
-
173
-
-
0033064273
-
The role of pRb2/p130 protein in diagnosing lung carcinoma on fine needle aspiration biopsies
-
MINIMO C, BIBO M, CLAUDIO PP, DE LUCA A, GIORDANO A: The role of pRb2/p130 protein in diagnosing lung carcinoma on fine needle aspiration biopsies. Pathol. Res. Pract. (1999) 195:67-70.
-
(1999)
Pathol. Res. Pract.
, vol.195
, pp. 67-70
-
-
Minimo, C.1
Bibo, M.2
Claudio, P.P.3
De Luca, A.4
Giordano, A.5
-
174
-
-
0031887422
-
Expression of the retinoblastoma related gene Rb2/p130 correlates with clinical outcome in endometrial cancer
-
SUSINI T, BALDI F, HOWARD CM et al.: Expression of the retinoblastoma related gene Rb2/p130 correlates with clinical outcome in endometrial cancer. J. Clin. Oncol. (1998)16:1085-1093.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1085-1093
-
-
Susini, T.1
Baldi, F.2
Howard, C.M.3
-
175
-
-
0033055803
-
Differential expression of the retinoblastoma gene family members in choroidal melanoma: Prognostic significance
-
MASSARO-GIORDANO M, BALDI G, DE LUCA A, BALDI A, GIORDANO A: Differential expression of the retinoblastoma gene family members in choroidal melanoma: prognostic significance. Clin. Cancer Res. (1999) 5:1455-1458.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1455-1458
-
-
Massaro-Giordano, M.1
Baldi, G.2
De Luca, A.3
Baldi, A.4
Giordano, A.5
-
176
-
-
17144457159
-
Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: Distinct mechanisms of cell growth control
-
LEONCINI L, BELLAN C, COSSU A et al: Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control. Clin. Cancer Res. (1999) 5:4065-4072.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4065-4072
-
-
Leoncini, L.1
Bellan, C.2
Cossu, A.3
-
177
-
-
0034643917
-
Structure of the human retinoblastoma-related p107 gene and its intragenic detection in a B-cell lymphoma cell line
-
ICHIMURA K, HANAFUSA H, TAKIMOTO1 H et al: Structure of the human retinoblastoma-related p107 gene and its intragenic detection in a B-cell lymphoma cell line. Gene (2000) 251:37-43.
-
(2000)
Gene
, vol.251
, pp. 37-43
-
-
Ichimura, K.1
Hanafusa, H.2
Takimoto, H.3
-
178
-
-
0031934761
-
Molecular abnormalities in lung cancer
-
SALGIA R, SKARIN AT: Molecular abnormalities in lung cancer. J. Clin. Oncol (1998) 16:1207-1217.
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 1207-1217
-
-
Salgia, R.1
Skarin, A.T.2
-
179
-
-
0028070540
-
RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma and mesothelioma
-
SHIMIZU E, COXON A, OTTERSON GA et al: RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma and mesothelioma. Oncogene (1994) 9:2441-2448.
-
(1994)
Oncogene
, vol.9
, pp. 2441-2448
-
-
Shimizu, E.1
Coxon, A.2
Otterson, G.A.3
-
180
-
-
0030978810
-
Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma
-
HELIN K, HOLM K, NIEBUHR A et al: Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma. Proc. Natl. Acad. Sci. USA (1997) 94:6933-6938.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6933-6938
-
-
Helin, K.1
Holm, K.2
Niebuhr, A.3
-
181
-
-
0031934761
-
Molecular abnormality in lung cancer.J
-
SLAGIA R, SKARIN AT: Molecular abnormality in lung cancer. J. Clin. Oncol (1998) 16:1207-1217.
-
(1998)
Clin. Oncol
, vol.16
, pp. 1207-1217
-
-
Slagia, R.1
Skarin, A.T.2
-
182
-
-
0030989021
-
Altered retinoblastoma protein expression in nonsmall cell lung cancer: Its synergistic effects with altered ras and p53 protein status on prognosis
-
DOSAKA-AKITA H, HU SX, FUJINO M et al: Altered retinoblastoma protein expression in nonsmall cell lung cancer: its synergistic effects with altered ras and p53 protein status on prognosis. Cancer (1997) 79:1329-1337.
-
(1997)
Cancer
, vol.79
, pp. 1329-1337
-
-
Dosaka-Akita, H.1
Sx, H.U.2
Fujino, M.3
-
184
-
-
0025899109
-
Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas
-
XU HJ, HU SX, CAGLE PT, MOORE GE, BENEDICT WF: Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas. Cancer Res. (1991) 51:2735-2739.
-
(1991)
Cancer Res.
, vol.51
, pp. 2735-2739
-
-
Hj, X.U.1
Sx, H.U.2
Cagle, P.T.3
Moore, G.E.4
Benedict, W.F.5
-
185
-
-
0027203330
-
The retinoblastoma gene: Will therapeutic use of its tumor suppressor properties be possible?
-
BIGNON YJ, RIO P: The retinoblastoma gene: will therapeutic use of its tumor suppressor properties be possible? Bull. Cancer. (1993) 80:704-712.
-
(1993)
Bull. Cancer.
, vol.80
, pp. 704-712
-
-
Bignon, Y.J.1
Rio, P.2
-
186
-
-
0030577120
-
Papillomavirus infections-a major cause of human cancers
-
ZUR HAUSEN H: Papillomavirus infections-a major cause of human cancers. Biochim. Biophys. Acta. (1996) 1288:F55-F78.
-
(1996)
Biochim. Biophys. Acta.
, vol.1288
-
-
Zur Hausen, H.1
-
187
-
-
0031874790
-
Human malignant mesothelioma of the pleura: New perspectives for diagnosis and therapy
-
PROCOPIO A, STRIZZI L, GIUFFRIDA A et al: Human malignant mesothelioma of the pleura: new perspectives for diagnosis and therapy. Monaldi Arch. Chest Dis. (1998) 53:241-243.
-
(1998)
Monaldi Arch. Chest Dis.
, vol.53
, pp. 241-243
-
-
Procopio, A.1
Strizzi, L.2
Giuffrida, A.3
-
188
-
-
0031609439
-
Simian virus 40-like DNA sequences and large-T antigen-retinoblastoma family protein pRb2/p130 interaction in human mesothelioma
-
MUTTI L, DE LUCA A, CLAUDIO PP et al: Simian virus 40-like DNA sequences and large-T antigen-retinoblastoma family protein pRb2/p130 interaction in human mesothelioma. Dev. Biol. Stand. (1998) 9:47-53.
-
(1998)
Dev. Biol. Stand.
, vol.9
, pp. 47-53
-
-
Mutti, L.1
De Luca, A.2
Claudio, P.P.3
-
189
-
-
0033590631
-
Ectopic expression of pRb2/p130 suppresses the tumorigen-icity of the c-erbB-2-overexpressing SKOV3 tumor cell line
-
PUPA SM, HOWARD CM, INVERNIZZI AM et al: Ectopic expression of pRb2/p130 suppresses the tumorigen-icity of the c-erbB-2-overexpressing SKOV3 tumor cell line. Oncogene (1999) 18:651-656.
-
(1999)
Oncogene
, vol.18
, pp. 651-656
-
-
Pupa, S.M.1
Howard, C.M.2
Invernizzi, A.M.3
-
190
-
-
0030860227
-
Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector
-
PARR MJ, MANOME Y, TANAKA T et al: Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector. Nature Med. (1997) 3:1145-1149.
-
(1997)
Nature Med.
, vol.3
, pp. 1145-1149
-
-
Parr, M.J.1
Manome, Y.2
Tanaka, T.3
|