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Volumn 5, Issue 2, 1998, Pages 132-140

pRb and the Cdks in apoptosis and the cell cycle

Author keywords

Apoptosis; Cdc2; Cdks; Cell cycle; Cyclins; pRb

Indexed keywords

CYCLIN DEPENDENT KINASE; PROTEIN P53; PROTEINASE; RETINOBLASTOMA PROTEIN;

EID: 0031817711     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400323     Document Type: Review
Times cited : (105)

References (84)
  • 1
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis. an interleukin 1 beta-converting enzyme-like protease as candidate
    • An B and Dou QP (1996) Cleavage of retinoblastoma protein during apoptosis. an interleukin 1 beta-converting enzyme-like protease as candidate. Cancer Res 56:438-442
    • (1996) Cancer Res , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2
  • 2
    • 0342434874 scopus 로고
    • The retinoblastoma protein copunfies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F
    • Bagchi S, Weinmann R and Raychaudhuri P (1992) The retinoblastoma protein copunfies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F. Cell 65 1053-1061
    • (1992) Cell , vol.65 , pp. 1053-1061
    • Bagchi, S.1    Weinmann, R.2    Raychaudhuri, P.3
  • 4
    • 0030999788 scopus 로고    scopus 로고
    • Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding
    • Chen W-D, Otterson GA, Lipkowitz S, Khlerf SN, Coxon AB and Kaye FJ (1997) Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding. Oncogene 14: 1243-1248
    • (1997) Oncogene , vol.14 , pp. 1243-1248
    • Chen, W.-D.1    Otterson, G.A.2    Lipkowitz, S.3    Khlerf, S.N.4    Coxon, A.B.5    Kaye, F.J.6
  • 9
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1 A, which is inhibited by E1B
    • Debbas M and White E (1993) Wild-type p53 mediates apoptosis by E1 A, which is inhibited by E1B. Genes Dev. 7: 546-554
    • (1993) Genes Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 12
    • 0030943468 scopus 로고    scopus 로고
    • Fas stimulation induces RB dephosphorylation and proteolysis that is blocked by inhibitors of the ICE protease family
    • Dou QP, An B, Antoku K and Johnson DE (1997) Fas stimulation induces RB dephosphorylation and proteolysis that is blocked by inhibitors of the ICE protease family. J Cell. Biochem 64: 585-594
    • (1997) J Cell. Biochem , vol.64 , pp. 585-594
    • Dou, Q.P.1    An, B.2    Antoku, K.3    Johnson, D.E.4
  • 13
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing and identity crisis
    • Elledge SJ (1996) Cell cycle checkpoints: preventing and identity crisis Science 274: 1664-1671
    • (1996) Science , vol.274 , pp. 1664-1671
    • Elledge, S.J.1
  • 14
    • 0028842645 scopus 로고
    • Cellular responses to DNA damage: Cell-cycle checkpoints, apoptosis, and the roles of p53 and ATM
    • Enoch T and Norbury C (1995) Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis, and the roles of p53 and ATM. Trends Biochem Sci. 20: 426-430
    • (1995) Trends Biochem Sci. , vol.20 , pp. 426-430
    • Enoch, T.1    Norbury, C.2
  • 19
    • 0028324310 scopus 로고
    • Analysis of cell cycle-regulated gene expression in postmitotic neurons: Selective induction of Cyclin D1 during programmed cell death
    • Freeman RS, Estus S and Johnson EM (1994) Analysis of cell cycle-regulated gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death. Neuron 12: 343-355
    • (1994) Neuron , vol.12 , pp. 343-355
    • Freeman, R.S.1    Estus, S.2    Johnson, E.M.3
  • 20
    • 0028137084 scopus 로고
    • p53: A glimpse at the puppet behind the shadow play
    • Friend S (1994) p53: a glimpse at the puppet behind the shadow play. Science 265: 334-335
    • (1994) Science , vol.265 , pp. 334-335
    • Friend, S.1
  • 21
    • 0029794386 scopus 로고    scopus 로고
    • Activation of apoptosis pathways by granzyme B
    • Greenberg AH (1996) Activation of apoptosis pathways by granzyme B. Cell Death Differ 3: 269-274
    • (1996) Cell Death Differ , vol.3 , pp. 269-274
    • Greenberg, A.H.1
  • 23
    • 10244227982 scopus 로고    scopus 로고
    • Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis
    • Han EK, Begemann M, Sgambato A, Soh JW, Doki Y, Xing WQ, Liu W and Weinstein IB (1996) Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis. Cell Growth Differ 7: 699-710
    • (1996) Cell Growth Differ , vol.7 , pp. 699-710
    • Han, E.K.1    Begemann, M.2    Sgambato, A.3    Soh, J.W.4    Doki, Y.5    Xing, W.Q.6    Liu, W.7    Weinstein, I.B.8
  • 24
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH and Kastan MB (1994) Cell cycle control and cancer. Science 266: 1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 25
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRB
    • Haupt Y, Rowan S and Oren M (1995) p53-mediated apoptosis in HeLa cells can be overcome by excess pRB. Oncogene 10: 1563-1571
    • (1995) Oncogene , vol.10 , pp. 1563-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 26
    • 0027244234 scopus 로고
    • Human weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase
    • Heald R, McLoughlin M and McKeon F (1993) Human weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase. Cell 74: 463-474
    • (1993) Cell , vol.74 , pp. 463-474
    • Heald, R.1    McLoughlin, M.2    McKeon, F.3
  • 27
    • 0027382336 scopus 로고
    • Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
    • Helm K, Harlow E and Fattaey A (1993) Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol. Cell. Biol. 13: 6501-6508
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6501-6508
    • Helm, K.1    Harlow, E.2    Fattaey, A.3
  • 28
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes KA, Ransom N, Papermaster DS, Lasudry JG, Albert DM and Windle JJ (1994) Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev. 8: 1300-1310
    • (1994) Genes Dev. , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.4    Albert, D.M.5    Windle, J.J.6
  • 31
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson MD, Weil M and Raff MC (1997) Programmed cell death in animal development. Cell 88: 347-354
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 32
    • 0141630973 scopus 로고
    • Cyclin D3 sensitizes tumor cells to TNF-induced, c-Myc-dependent apoptosis
    • Janicke RU, Lin XY, H LF and Porter AG (1986) Cyclin D3 sensitizes tumor cells to TNF-induced, c-Myc-dependent apoptosis. Mol. Cell. Biol. 16: 5245-5253
    • (1986) Mol. Cell. Biol. , vol.16 , pp. 5245-5253
    • Janicke, R.U.1    Lin, X.Y.2    H, L.F.3    Porter, A.G.4
  • 33
    • 0030462563 scopus 로고    scopus 로고
    • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
    • Janicke RU, Walker PA. Lin XY and Porter AG (1996) Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J. 15: 6969-6978
    • (1996) EMBO J. , vol.15 , pp. 6969-6978
    • Janicke, R.U.1    Walker, P.A.2    Lin, X.Y.3    Porter, A.G.4
  • 34
    • 0029011805 scopus 로고
    • Cell cycle and apoptosis: Common pathways to life and death
    • King KL and Cidlowski JA (1995) Cell cycle and apoptosis: common pathways to life and death J Cell Biochem 58: 175-180
    • (1995) J Cell Biochem , vol.58 , pp. 175-180
    • King, K.L.1    Cidlowski, J.A.2
  • 35
    • 0030031514 scopus 로고    scopus 로고
    • Cyclin D1 is an essential mediator of neuronal cell death
    • Kranenburg O, van der Eb AJ and Zantema A (1996) Cyclin D1 is an essential mediator of neuronal cell death EMBO J 15 46-54
    • (1996) EMBO J , vol.15 , pp. 46-54
    • Kranenburg, O.1    Van Der Eb, A.J.2    Zantema, A.3
  • 36
    • 0029794385 scopus 로고    scopus 로고
    • The ICE family of cysteine proteases as effectors of cell death
    • Kumar S and Lavin MF (1996) The ICE family of cysteine proteases as effectors of cell death. Cell Death Differ. 3: 255-267
    • (1996) Cell Death Differ. , vol.3 , pp. 255-267
    • Kumar, S.1    Lavin, M.F.2
  • 38
    • 0027986982 scopus 로고
    • DP and E2F proteins: Coordinating transcription with cell cycle progression
    • Lam EW and LaThangue NB (1994) DP and E2F proteins: coordinating transcription with cell cycle progression Curr Opin. Cell Biol. 6: 859-866
    • (1994) Curr Opin. Cell Biol. , vol.6 , pp. 859-866
    • Lam, E.W.1    LaThangue, N.B.2
  • 39
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
    • Lam EW-F and Watson RJ (1993) An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription EMBO J. 12: 2705-2713
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.-F.1    Watson, R.J.2
  • 42
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine A (1997) p53, the cellular gatekeeper for growth and division. Cell 88 323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.1
  • 43
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li CJ, Friedman DJ, Wang C, Metelev V and Pardee AB (1995) Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268 429-431
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.B.5
  • 44
    • 0028865245 scopus 로고
    • Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
    • Lindahl T, Satoh MS, Poiner GG and Klungland A (1995) Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem. Sci. 20: 405-411
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 405-411
    • Lindahl, T.1    Satoh, M.S.2    Poiner, G.G.3    Klungland, A.4
  • 45
    • 0026035524 scopus 로고
    • mik1 and wee1 cooperate in the inhibitory tryosine phosphorylation of cdc2
    • Lundgren K, Walwork N, Booher R, Bembski M, Kirshner M and Beach D (1991) mik1 and wee1 cooperate in the inhibitory tryosine phosphorylation of cdc2. Cell 64: 111-121
    • (1991) Cell , vol.64 , pp. 111-121
    • Lundgren, K.1    Walwork, N.2    Booher, R.3    Bembski, M.4    Kirshner, M.5    Beach, D.6
  • 46
    • 0028880855 scopus 로고
    • Cyclins, cyclin-dependent kinases and cdk inhibitors: Implications in cell cycle control and cancer
    • MacLachlan TK, Sang N and Giordano A (1995) Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer. Crit. Rev. Eukaryot. Gene Expr. 5: 127-156
    • (1995) Crit. Rev. Eukaryot. Gene Expr. , vol.5 , pp. 127-156
    • MacLachlan, T.K.1    Sang, N.2    Giordano, A.3
  • 49
    • 0025180506 scopus 로고
    • p53 is associated with p34cdc-2 in transformed cells
    • Milner J, Cook A and Mason J (1990) p53 is associated with p34cdc-2 in transformed cells. EMBO J. 9: 2885-2889
    • (1990) EMBO J. , vol.9 , pp. 2885-2889
    • Milner, J.1    Cook, A.2    Mason, J.3
  • 50
    • 0027199498 scopus 로고
    • Interaction of adenoviral proteins with pRB and p53
    • Moran E (1993) Interaction of adenoviral proteins with pRB and p53. FASEB J. 7: 880-885
    • (1993) FASEB J. , vol.7 , pp. 880-885
    • Moran, E.1
  • 51
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser SD, Williams BO, Jacks T and DePinho RA (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 52
    • 0028918028 scopus 로고
    • Transcnptional regulation during the mammalian cell cycle
    • Muller R (1995) Transcnptional regulation during the mammalian cell cycle. Trends Genet 11: 173-178
    • (1995) Trends Genet , vol.11 , pp. 173-178
    • Muller, R.1
  • 53
    • 0029833679 scopus 로고    scopus 로고
    • The rise and fall of apoptosis during multistage tumorigenesis: Down-modulation contributes to tumor progression from angiogenic progenitors
    • Naik P, Kamm J and Hanahan D (1996) The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors. Genes Dev. 10: 2105-2116
    • (1996) Genes Dev. , vol.10 , pp. 2105-2116
    • Naik, P.1    Kamm, J.2    Hanahan, D.3
  • 54
    • 0029807526 scopus 로고    scopus 로고
    • Viewpoint, putting the cell cycle inorder
    • Nasmyth K (1996) Viewpoint, putting the cell cycle inorder. Science 274: 1643-1645
    • (1996) Science , vol.274 , pp. 1643-1645
    • Nasmyth, K.1
  • 55
    • 0027989510 scopus 로고
    • Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase
    • Oberhammer FA, Hochegger K, Froschl G, Tiefenbacher R and Pavelka M (1994) Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase J. Cell. Biol. 126: 827-837
    • (1994) J. Cell. Biol. , vol.126 , pp. 827-837
    • Oberhammer, F.A.1    Hochegger, K.2    Froschl, G.3    Tiefenbacher, R.4    Pavelka, M.5
  • 56
    • 0029116545 scopus 로고
    • Inactivation of Cdc2 increase the level of apoptosis induced by DNA damage
    • Ongkeko W, Ferguson DJP, Harris AL and Norbury C (1995) Inactivation of Cdc2 increase the level of apoptosis induced by DNA damage. J. Cell Sci 108: 2897-2904
    • (1995) J. Cell Sci , vol.108 , pp. 2897-2904
    • Ongkeko, W.1    Ferguson, D.J.P.2    Harris, A.L.3    Norbury, C.4
  • 57
    • 0029739541 scopus 로고    scopus 로고
    • Retinoblastoma protein family in cell cycle and cancer: A review
    • Paggi MG, Baldi A, Bonetto Fand Giordano A (1996) Retinoblastoma protein family in cell cycle and cancer: A review. J. Cell Biochem. 62: 418-430
    • (1996) J. Cell Biochem. , vol.62 , pp. 418-430
    • Paggi, M.G.1    Baldi, A.2    Bonetto, F.3    Giordano, A.4
  • 59
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin X-Q, Livingston DM, Kaelin WGJ and Adams PD (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad. Sci. USA 91: 10918-10922
    • (1994) Proc Natl Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin, W.G.J.3    Adams, P.D.4
  • 60
    • 0029888119 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis
    • Rudolph B, Saffrich R, Zwicker J, Henglein B, Muller R, Ansorge W and Eilers M (1996) Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis. EMBO J 15: 3065-3076
    • (1996) EMBO J , vol.15 , pp. 3065-3076
    • Rudolph, B.1    Saffrich, R.2    Zwicker, J.3    Henglein, B.4    Muller, R.5    Ansorge, W.6    Eilers, M.7
  • 61
    • 0023662312 scopus 로고
    • Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
    • Russel P and Nurse P (1987) Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 49: 559-567
    • (1987) Cell , vol.49 , pp. 559-567
    • Russel, P.1    Nurse, P.2
  • 62
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ and Howley PM (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63: 1129-1136
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 63
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
    • Shan B and Lee W-H (1994) Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis Mol. Cell. Bio. 14: 8166-8173
    • (1994) Mol. Cell. Bio. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.-H.2
  • 64
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ (1996) Cancer cell cycles Science 274: 1672-1677
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 67
    • 0028873880 scopus 로고
    • Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage
    • Shimizu T, O'Conner PM, Kohn KW and Pommier Y (1995) Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage. Cancer Res. 15: 228-231
    • (1995) Cancer Res. , vol.15 , pp. 228-231
    • Shimizu, T.1    O'Conner, P.M.2    Kohn, K.W.3    Pommier, Y.4
  • 68
    • 0030444208 scopus 로고    scopus 로고
    • Apoptosis induced by ectopic expression of cyclin D1 by not cyclin E
    • Sofer-Levi Y and Resnitzky D (1996) Apoptosis induced by ectopic expression of cyclin D1 by not cyclin E, Oncogene 13: 2431-2437
    • (1996) Oncogene , vol.13 , pp. 2431-2437
    • Sofer-Levi, Y.1    Resnitzky, D.2
  • 71
    • 0031016121 scopus 로고    scopus 로고
    • RB kinases and RB-binding proteins: New points of view
    • Taya Y (1997) RB kinases and RB-binding proteins: new points of view Trends Biochem Sci. 22: 14-17
    • (1997) Trends Biochem Sci. , vol.22 , pp. 14-17
    • Taya, Y.1
  • 72
  • 73
    • 0027236269 scopus 로고
    • Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes
    • Vousden K (1993) Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes. FASEB J. 7: 872-879
    • (1993) FASEB J. , vol.7 , pp. 872-879
    • Vousden, K.1
  • 75
    • 0029033861 scopus 로고
    • The retinoblastoma protein and the cell cycle
    • Weinberg RA (1995) The retinoblastoma protein and the cell cycle. Cell 81 323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 76
    • 0029043782 scopus 로고
    • Mechanism of active transcriptional repression by the retinoblastoma protein
    • Weintraub SJ, Chow KN, Luo RX, Zhang SH, He S and Dean DC (1995) Mechanism of active transcriptional repression by the retinoblastoma protein. Nature 375: 812-815
    • (1995) Nature , vol.375 , pp. 812-815
    • Weintraub, S.J.1    Chow, K.N.2    Luo, R.X.3    Zhang, S.H.4    He, S.5    Dean, D.C.6
  • 77
    • 0026636908 scopus 로고
    • Retinoblastoma protein switches the E2F site from positive to negative element
    • Weintraub SJ, Prater CA and Dean DC (1992) Retinoblastoma protein switches the E2F site from positive to negative element. Nature 358: 259-261
    • (1992) Nature , vol.358 , pp. 259-261
    • Weintraub, S.J.1    Prater, C.A.2    Dean, D.C.3
  • 78
    • 0026049728 scopus 로고
    • Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
    • White E, Cipriani R, Sabbatini P and Denton A (1991) Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins. J. Virol 65: 2968-2978
    • (1991) J. Virol , vol.65 , pp. 2968-2978
    • White, E.1    Cipriani, R.2    Sabbatini, P.3    Denton, A.4
  • 80
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu X and Levine AJ (1994) p53 and E2F-1 cooperate to mediate apoptosis Proc. Natl. Acad. Sci. USA 91: 3602-3606
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 84
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang H, Hannon GJ and Beach D (1994) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev. 81: 1750-1758
    • (1994) Genes Dev. , vol.81 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3


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