Hydrogen bonding part 46: A review of the correlation and prediction of transport properties by an LFER method: Physicochemical properties, brain penetration and skin permeability

Pesticide Science

Volumn 55, Issue 1, 1999, Pages 78-88

  Abraham, M H ^a   Chadha, H S ^a   Martins, F ^a   Mitchell, R C ^a   Bradbury, M W ^a   Gratton, J A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Brain penetration; Hydrogen bonding; LFER; QSAR; Skin permeation; Solvation

Indexed keywords

BLOOD BRAIN BARRIER; GAS; HYDROGEN BOND; LINEAR FREE ENERGY RELATIONSHIP; PHYSICOCHEMICAL CONCEPTS; SKIN PERMEABILITY; SOLUBILITY; SOLVATION; VAPOR; WATER;

DRUG; SOLVENT; WATER;

ACIDITY; ALKALINITY; AQUEOUS SOLUTION; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; HUMAN; HYDROGEN BOND; NONHUMAN; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SKIN PENETRATION; SOLUBILITY; SOLVATION; TRANSPORT KINETICS;

EID: 0033062152     PISSN: 0031613X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9063(199901)55:1<78::AID-PS853>3.0.CO;2-7     Document Type: Article

References (46)