Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas

Journal of Autoimmunity

Volumn 23, Issue 4, 2004, Pages 301-309

  Augstein, Petra ^a   Bahr, Jeanette ^a   Wachlin, Gerhild ^b   Heinke, Peter ^a   Berg, Sabine ^a   Salzsieder, Eckhard ^a   Harrison, Leonard C ^c  

^a Institut fur Diabetes 'Gerhardt Katsch'   (Germany)

^b Germany ^*  (Germany)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

cell apoptosis; Caspase 3, Fas expression; FasL; IFN ; IL 1 ; NIT 1 cells; NOD mouse islets; thymocytes; Type 1 diabetes

Indexed keywords

CASPASE 3; CYTOKINE; DEXAMETHASONE; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 1BETA;

APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CELL LYSATE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; INSULINOMA; MALE; MOUSE; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN INTERACTION; THYMOCYTE; UPREGULATION; VALIDATION PROCESS;

ANIMALS; APOPTOSIS; BIOLOGICAL ASSAY; CASPASE 3; CASPASES; CELLS, CULTURED; CYTOKINES; DEXAMETHASONE; DIABETES MELLITUS, TYPE 1; FAS LIGAND PROTEIN; INSULINOMA; INTERFERON TYPE II; INTERLEUKIN-1; ISLETS OF LANGERHANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED NOD; PANCREATIC NEOPLASMS; THYMUS GLAND; UP-REGULATION;

EID: 9644290899     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaut.2004.09.006     Document Type: Article

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