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Volumn 35, Issue 6, 2002, Pages 369-375

Transmembrane TNF and IFNγ induce caspase-independent death of primary mouse pancreatic beta cells

Author keywords

Apoptosis; Caspase; Cytokines; Diabetes

Indexed keywords

CASPASE; CASPASE 3; CYTOKINE; DNA; GAMMA INTERFERON; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR; CASP3 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0036710448     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/0891693021000024834     Document Type: Article
Times cited : (25)

References (38)
  • 1
    • 0035231988 scopus 로고    scopus 로고
    • How beta cells die in type 1 diabetes
    • Thomas, H.E. and Kay, TW. (2001) "How beta cells die in type 1 diabetes", Curr. Dir. Autoimmun. 4, 144-170.
    • (2001) Curr. Dir. Autoimmun. , vol.4 , pp. 144-170
    • Thomas, H.E.1    Kay, T.W.2
  • 2
    • 0033305236 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic beta cells
    • Stephens, L.A., Thomas, HE., Ming, L., Grell, M., Darwiche, R., Volodin, L., et al. (1999) "Tumor necrosis factor-alpha-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic beta cells", Endocrinology 140, 3219-3227.
    • (1999) Endocrinology , vol.140 , pp. 3219-3227
    • Stephens, L.A.1    Thomas, H.E.2    Ming, L.3    Grell, M.4    Darwiche, R.5    Volodin, L.6
  • 3
    • 0033561630 scopus 로고    scopus 로고
    • TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes
    • Kagi, D., Ho, A., Odermatt, B., Zakarian, A., Ohashi, P.S. and Mak, T.W. (1999) "TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes", J. Immunol. 162, 4598-4605.
    • (1999) J. Immunol. , vol.162 , pp. 4598-4605
    • Kagi, D.1    Ho, A.2    Odermatt, B.3    Zakarian, A.4    Ohashi, P.S.5    Mak, T.W.6
  • 4
    • 0033526068 scopus 로고    scopus 로고
    • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha
    • Pakala, S.V., Chivetta, M., Kelly, C.B. and Katz, J.D. (1999) "In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha", J. Exp. Med. 189, 1053-1062.
    • (1999) J. Exp. Med. , vol.189 , pp. 1053-1062
    • Pakala, S.V.1    Chivetta, M.2    Kelly, C.B.3    Katz, J.D.4
  • 5
    • 0032214715 scopus 로고    scopus 로고
    • Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
    • Green, E.A., Eynon, E.E. and Flavell, R.A. (1998) "Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens", Immunity 9, 733-743.
    • (1998) Immunity , vol.9 , pp. 733-743
    • Green, E.A.1    Eynon, E.E.2    Flavell, R.A.3
  • 6
    • 0033625501 scopus 로고    scopus 로고
    • The temporal importance of TNFalpha expression in the development of diabetes
    • Green, E.A. and Flavell, R.A. (2000) "The temporal importance of TNFalpha expression in the development of diabetes", Immunity 12, 459-469.
    • (2000) Immunity , vol.12 , pp. 459-469
    • Green, E.A.1    Flavell, R.A.2
  • 7
    • 0035877181 scopus 로고    scopus 로고
    • A dual role for TNF-alpha in type 1 diabetes: Islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis
    • Christen, U., Wolfe, T., Mohrle, U., Hughes, A.C., Rodrigo, E., Green, E.A., et al. (2001) "A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis", J. Immunol. 166, 7023-7032.
    • (2001) J. Immunol. , vol.166 , pp. 7023-7032
    • Christen, U.1    Wolfe, T.2    Mohrle, U.3    Hughes, A.C.4    Rodrigo, E.5    Green, E.A.6
  • 8
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley, R.M., Killeen, N. and Lenardo, M.J. (2001) "The TNF and TNF receptor superfamilies: integrating mammalian biology", Cell 104, 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 9
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
    • Corbett, J.A. and McDaniel, M.L. (1995) "Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase", J. Exp. Med. 181, 559-568.
    • (1995) J. Exp. Med. , vol.181 , pp. 559-568
    • Corbett, J.A.1    McDaniel, M.L.2
  • 11
    • 0035313059 scopus 로고    scopus 로고
    • IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death
    • Suk, K., Kim, S., Kim, Y.H., Kim, K.A., Chang, I., Yagita, H., et al. (2001) "IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death", J. Immunol. 166, 4481-4489.
    • (2001) J. Immunol. , vol.166 , pp. 4481-4489
    • Suk, K.1    Kim, S.2    Kim, Y.H.3    Kim, K.A.4    Chang, I.5    Yagita, H.6
  • 12
    • 0024281428 scopus 로고
    • A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF
    • Kriegler, M., Perez, C., DeFay, K., Albert, I. and Lu, S.D. (1988) "A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF", Cell 53, 45-53.
    • (1988) Cell , vol.53 , pp. 45-53
    • Kriegler, M.1    Perez, C.2    DeFay, K.3    Albert, I.4    Lu, S.d.5
  • 13
    • 17944381638 scopus 로고    scopus 로고
    • Membrane-bound tnf supports secondary lymphoid organ structure but is subservient to secreted tnf in driving autoimmune inflammation
    • Ruuls, S.R., Hoek, R.M., Ngo, V.N., McNeil, T., Lucian, L.A., Janatpour, M.J., et al. (2001) "Membrane-bound tnf supports secondary lymphoid organ structure but is subservient to secreted tnf in driving autoimmune inflammation", Immunity 15, 533-543.
    • (2001) Immunity , vol.15 , pp. 533-543
    • Ruuls, S.R.1    Hoek, R.M.2    Ngo, V.N.3    McNeil, T.4    Lucian, L.A.5    Janatpour, M.J.6
  • 14
    • 0033592984 scopus 로고    scopus 로고
    • Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)
    • Huang, D.C., Hahne, M., Schroeter, M., Frei, K., Fontana, A., Villunger, A., et al. (1999) "Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)", Proc. Natl Acad. Sci. USA 96, 14871-14876.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 14871-14876
    • Huang, D.C.1    Hahne, M.2    Schroeter, M.3    Frei, K.4    Fontana, A.5    Villunger, A.6
  • 15
    • 0025878776 scopus 로고
    • NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse
    • Hamaguchi, K., Gaskins, H.R. and Leiter, E.H. (1991) "NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse", Diabetes 40, 842-849.
    • (1991) Diabetes , vol.40 , pp. 842-849
    • Hamaguchi, K.1    Gaskins, H.R.2    Leiter, E.H.3
  • 16
    • 0033178741 scopus 로고    scopus 로고
    • Evidence that beta cell death in the nonobese diabetic mouse is Fas independent
    • Thomas, H.E., Darwiche, R., Corbett, J.A. and Kay, T.W. (1999) "Evidence that beta cell death in the nonobese diabetic mouse is Fas independent", J. Immunol. 163, 1562-1569.
    • (1999) J. Immunol. , vol.163 , pp. 1562-1569
    • Thomas, H.E.1    Darwiche, R.2    Corbett, J.A.3    Kay, T.W.4
  • 17
    • 0029557950 scopus 로고
    • A new method for isolation of murine islets with markedly improved yields
    • Liu, M. and Shapiro, M.E. (1995) "A new method for isolation of murine islets with markedly improved yields", Transplant. Proc. 27, 3208-3210.
    • (1995) Transplant. Proc. , vol.27 , pp. 3208-3210
    • Liu, M.1    Shapiro, M.E.2
  • 18
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., Migliorati, G., Pagliacci, M.C., Grignani, F. and Riccardi, C. (1991) "A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry", J. Immunol. Methods 139, 271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 20
    • 0031171741 scopus 로고    scopus 로고
    • Protection of NIT-1 pancreatic beta-cells from immune attack by inhibition of NF-kappaB
    • Stephens, L.A., Thomas, H.E. and Kay, T.W. (1997) "Protection of NIT-1 pancreatic beta-cells from immune attack by inhibition of NF-kappaB", J. Autoimmun. 10, 293-298.
    • (1997) J. Autoimmun. , vol.10 , pp. 293-298
    • Stephens, L.A.1    Thomas, H.E.2    Kay, T.W.3
  • 21
    • 0030698766 scopus 로고    scopus 로고
    • A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling
    • Alexopoulou, L., Pasparakis, M. and Kollias, G. (1997) "A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling", Eur. J. Immunol. 27, 2588-2592.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2588-2592
    • Alexopoulou, L.1    Pasparakis, M.2    Kollias, G.3
  • 22
    • 18744438211 scopus 로고    scopus 로고
    • Detection of membrane-bound tumor necrosis factor (TNF): An analysis of TNF-specific reagents
    • Gerspach, J., Gotz, A., Zimmermann, G., Kolle, C., Bottinger, H. and Grell, M. (2000) "Detection of membrane-bound tumor necrosis factor (TNF): an analysis of TNF-specific reagents", Microsc. Res. Tech. 50, 243-250.
    • (2000) Microsc. Res. Tech. , vol.50 , pp. 243-250
    • Gerspach, J.1    Gotz, A.2    Zimmermann, G.3    Kolle, C.4    Bottinger, H.5    Grell, M.6
  • 23
    • 0035208918 scopus 로고    scopus 로고
    • Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells
    • Lakey, J.R., Suarez-Pinzon, W.L., Strynadka, K., Korbutt, G.S., Rajotte, R.V., Mabley, J.G., et al., (2001) "Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells", Lab. Investig. 81, 1683-1692.
    • (2001) Lab. Investig. , vol.81 , pp. 1683-1692
    • Lakey, J.R.1    Suarez-Pinzon, W.L.2    Strynadka, K.3    Korbutt, G.S.4    Rajotte, R.V.5    Mabley, J.G.6
  • 24
    • 0031827241 scopus 로고    scopus 로고
    • Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells
    • Darville, M.I. and Eizirik, D.L. (1998) "Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells", Diabetologia 41, 1101-1108.
    • (1998) Diabetologia , vol.41 , pp. 1101-1108
    • Darville, M.I.1    Eizirik, D.L.2
  • 25
    • 0032745109 scopus 로고    scopus 로고
    • A20 inhibits cytokine-induced apoptosis and nuclear factor kB-dependent gene activation in islets
    • Grey, S.T., Arvelo, M.B., Hasenkamp, W., Bach, F.H. and Ferran, C. (1999) "A20 inhibits cytokine-induced apoptosis and nuclear factor kB-dependent gene activation in islets", J. Exp. Med. 190, 1135-1145.
    • (1999) J. Exp. Med. , vol.190 , pp. 1135-1145
    • Grey, S.T.1    Arvelo, M.B.2    Hasenkamp, W.3    Bach, F.H.4    Ferran, C.5
  • 26
    • 0030885421 scopus 로고    scopus 로고
    • Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
    • Chu, Z.L., McKinsey, T.A., Liu, L., Gentry, J.J., Malim, M.H. and Ballard, D.W. (1997) "Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control", Proc. Natl Acad. Sci. USA 94, 10057-10062.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 10057-10062
    • Chu, Z.L.1    McKinsey, T.A.2    Liu, L.3    Gentry, J.J.4    Malim, M.H.5    Ballard, D.W.6
  • 27
    • 0035889252 scopus 로고    scopus 로고
    • Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling
    • De Smaele, E., Zazzeroni, F., Papa, S., Nguyen, D.U., Jin, R., Jones, J., et al., (2001) "Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling", Nature 414, 308-313.
    • (2001) Nature , vol.414 , pp. 308-313
    • De Smaele, E.1    Zazzeroni, F.2    Papa, S.3    Nguyen, D.U.4    Jin, R.5    Jones, J.6
  • 28
    • 0035891320 scopus 로고    scopus 로고
    • Inhibition of JNK activation through NF-kappaB target genes
    • Tang, G., Minemoto, Y., Dibling, B., Purcell, N.H., Li, Z., Karin, M., et al., (2001) "Inhibition of JNK activation through NF-kappaB target genes", Nature 414, 313-317.
    • (2001) Nature , vol.414 , pp. 313-317
    • Tang, G.1    Minemoto, Y.2    Dibling, B.3    Purcell, N.H.4    Li, Z.5    Karin, M.6
  • 29
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg, A.A. and Baltimore, D. (1996) "An essential role for NF-kappaB in preventing TNF-alpha-induced cell death", Science 274, 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 30
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang, C.Y., Mayo, M.W. and Baldwin, Jr., A.S. (1996) "TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB", Science 274, 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 32
    • 0034036353 scopus 로고    scopus 로고
    • Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells
    • Sekine, N., Ishikawa, T., Okazaki, T., Hayashi, M., Wollheim, C.B. and Fujita, T. (2000) "Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells", J. Cell. Physiol. 184, 46-57.
    • (2000) J. Cell. Physiol. , vol.184 , pp. 46-57
    • Sekine, N.1    Ishikawa, T.2    Okazaki, T.3    Hayashi, M.4    Wollheim, C.B.5    Fujita, T.6
  • 33
    • 0035966006 scopus 로고    scopus 로고
    • A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells
    • Cardozo, A.K., Heimberg, H., Heremans, Y., Leeman, R., Kutlu, B., Kruhoffer, M., et al., (2001) "A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells", J. Biol. Chem. 276, 48879-48886.
    • (2001) J. Biol. Chem. , vol.276 , pp. 48879-48886
    • Cardozo, A.K.1    Heimberg, H.2    Heremans, Y.3    Leeman, R.4    Kutlu, B.5    Kruhoffer, M.6
  • 34
    • 9244234507 scopus 로고    scopus 로고
    • The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300
    • Avantaggiati, M.L., Carbone, M., Graessmann, A., Nakatani, Y., Howard, B. and Levine, A.S. (1996) "The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300", EMBO J. 15, 2236-2248.
    • (1996) EMBO J , vol.15 , pp. 2236-2248
    • Avantaggiati, M.L.1    Carbone, M.2    Graessmann, A.3    Nakatani, Y.4    Howard, B.5    Levine, A.S.6
  • 35
    • 0024401714 scopus 로고
    • Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection
    • Campbell, I.L., Cutri, A., Wilkinson, D., Boyd, A.W. and Harrison, L.C. (1989) "Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection", Proc. Natl Acad. Sci. USA 86, 4282-4286.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 4282-4286
    • Campbell, I.L.1    Cutri, A.2    Wilkinson, D.3    Boyd, A.W.4    Harrison, L.C.5
  • 36
    • 0035576007 scopus 로고    scopus 로고
    • IFN-gamma affects homing of diabetogenic T cells
    • Savinov, A.Y., Wong, F.S. and Chervonsky, A.V. (2001) "IFN-gamma affects homing of diabetogenic T cells", J. Immunol. 167, 6637-6643.
    • (2001) J. Immunol. , vol.167 , pp. 6637-6643
    • Savinov, A.Y.1    Wong, F.S.2    Chervonsky, A.V.3
  • 37
    • 0032813549 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and the progression of diabetes in non-obese diabetic mice
    • Green, E.A. and Flavell, R.A. (1999) "Tumor necrosis factor alpha and the progression of diabetes in non-obese diabetic mice", Immunol. Rev. 169, 11-22.
    • (1999) Immunol. Rev. , vol.169 , pp. 11-22
    • Green, E.A.1    Flavell, R.A.2
  • 38
    • 0023856452 scopus 로고
    • Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha
    • Campbell, I.L., Oxbrow, L., West, J. and Harrison, L.C. (1988) "Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha", Mol. Endocrinol. 2, 101-107.
    • (1988) Mol. Endocrinol. , vol.2 , pp. 101-107
    • Campbell, I.L.1    Oxbrow, L.2    West, J.3    Harrison, L.C.4


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