Alpha-interferon and its effects on signalling pathways within cells

Current Protein and Peptide Science

Volumn 5, Issue 6, 2004, Pages 475-485

  Caraglia, Michele ^a,c   Vitale, Giovanni ^d   Marra, Monica ^a   Budillon, Alfredo ^c   Tagliaferri, Pierosandro ^b   Abbruzzese, Alberto ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

EGF R; eIF5A; Hypusine; Interferon ; ras; SOCS; STAT; Ubiquitin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA INTERFERON; ANTINEOPLASTIC AGENT; CASPASE; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 5A; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN KINASE C DELTA; PROTEIN P85; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAF PROTEIN; RAS PROTEIN; RECOMBINANT PROTEIN; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SUPPRESSOR OF CYTOKINE SIGNALING; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROTECTION; CELL SURVIVAL; CORRELATION ANALYSIS; DRUG EFFICACY; DRUG EXPOSURE; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; ENZYME INHIBITION; GENETIC TRANSFECTION; HEAD AND NECK CANCER; HUMAN; IN VITRO STUDY; KIDNEY CARCINOMA; MELANOMA; MITOSIS INHIBITION; MYELOMA; NONHUMAN; PROTEIN SYNTHESIS; RECOMBINANT DNA TECHNOLOGY; REVIEW; SIGNAL TRANSDUCTION; SOLID TUMOR; SQUAMOUS CELL CARCINOMA; UTERINE CERVIX CARCINOMA;

APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; HUMANS; INTERFERON-ALPHA; MODELS, BIOLOGICAL; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION;

EID: 9244253700     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389203043379378     Document Type: Review

References (145)

1. Pestka, S., Langer, J. A., Zoon, K.C. and Samuel, C.E. ( 1987) Ann. Rev. Biochem., 56, 727-777.
2. Pestka, S. (1981) Methods Enzymol., 78, 1-632.
3. Pestka, S. (1981) Methods Enzymol., 79, 1-677.
4. Pestka, S. (1986) Methods Enzymol., 119, 1-845.
5. Pestka, S. (2000) Biopolymers (PeptideScience), 55 254-287.
6. Bazan, J. F. (1990) Cell, 61, 753-754.
7. Bazan, J. F. (1990) Proc. Natl. Acad. Sci. USA, 87 6934-6
8. Thoreau, E., Petridou, B., Kelly, P.A., Djiane, J. and Mornon, J.B. (1991) FEBS Lett., 282, 26-31.
9. Kotenko, S. V. and Pestka, S. (2000) Oncogene, 19 2557-2565.
10. Schindler, C. and Darnell, J.E. Jr. (1995) Annu. Rev. Biochem., 64, 621-651.
11. Ihle, J.N. (1996) Cell, 84, 331-334.
12. Darnell, J.E., Jr. (1997) Science, 277, 1630-1635
13. Imada, K. and Leonard, W.J. (2000) Mol. Immunol., 37 1-11.
14. Takeda, K. and Akira, S. (2000) Cytokine Growth Factor Rev., 11, 199-207.
15. Williams, J.G. (2000) Curr. Opin. Genet. Dev., 10 503-507.
16. Bromberg, J.F. (2001) Bioessays, 23, 161-169.
17. Shuai, K., Stark, G.R., Kerr, I.M. and Darnell, J.E. Jr. ( 1993) Science, 261, 1744-1746.
18. Sadowski, H.B., Shuai, K., Darnell, J.E. Jr. and Gilman, M.Z. (1993) Science, 261, 1739-1744.
19. Darnell, J.E., Kerr, I.M. and Stark, G.R. (1994) Science, 264, 1415-1421.
20. Krammer, P.H. (2000) Nature, 407:789-795.
21. Los, M., Herr, I., Friesen, C., Fulda, S., Schulze-Osthoff, K. and Debatin, KM. (1997) Blood, 90, 3118-29.
22. Raza, A. (2000) Leuk. Res., 24, 63-72.
23. Sangfelt, O., Erickson, S., Castro, J., Heiden, T., Einhorn, S. and Grander, D. (1997) Cell Growth Differ., 8, 343-352.
24. Cai, J. and Jones, D.P. (1998) J. Biol. Chem., 273 11401-11404.
25. Dai, C. and Krantz, S.B. (1999) Blood, 93, 3309-3316.
26. Thyrell, L., Erickson, S., Zhivotovsky, B., Pokrovskaja, K., Sangfelt, O., Castro, J., Einhorn, S. and Grander, D. (2002) Oncogene., 21, 1251-1262.
27. Spets, H., Georgii-Hemming, P., Siljason, J., Nilsson, K. and Jernberg-Wiklund, H. (1998). Blood, 92, 2914-2923.
28. Roth, W., Wagenknecht, B., Dichgans, J. and Weller, M. ( 1998). J. Neuroimmunol., 87, 121-129.
29. Buechner, S. A., Wernli, M., Harr, T., Hahn, S., Itin, P. and Erb, P. (1997) J. Clin. Investig., 100, 2691-2696.
30. Chawla-Sarkar, M., Leaman, D.W. and Borden, E.C. (2001) Clin. Cancer Res., 7, 1821-1831.
31. Sanceau, J., Hiscott, J., Delattre, O. and Wietzerbin, J. ( 2000) Oncogene, 19, 3372-3383.
32. Panaretakis, T., Pokrovskaja, K., Shoshan, M.C. and Grandèr (2003) Oncogene, 22, 4543-4556.
33. Puthier, D., Thabard, W., Rapp, M., Etrillard, M., Harousseau, J., Bataille, R. and Armot, M. (2001) Br. J. Haematol., 112, 358-363.
34. Matsui, W., Huff, C.A., Vala, M., Barber, J., Smith, B.D. and Jones, R.J. (2003) Br. J. Haematol., 121, 251-258.
35. David, M., Petricoin, E. 3rd, Benjamin, C., Pine, R., Weber, M.J. and Larner, A.C. (1995) Science, 269, 1721-1723.
36. Uddin, S., Majchrzak, B., Woodson, J., Arunkumar, P., Alsayed, Y., Pine, R.,Young, P. R., Fish, E. N. and Platanias, L. C. ( 1999) J. Biol. Chem., 274, 30127-30131.
37. Goh, K. C., Haque, S. J. and Williams, B. R. G. (1999) EMBO J., 18, 5601-5609
38. Uddin, S., Lekmine, F., Sharma, N., Majchrzak, B., Mayer, I., Young, P. R., Bokoch, G. M., Fish, E. N. and Platanias, L. C. (2000 J. Biol. Chem., 275, 27634-27640.
39. Verma, A., Deb, D.K., Sassano, A., Uddin, S., Varga, G., Wickrema, A., Platanias, L.C. (2002) J. Biol. Chem., 277, 7726-7735.
40. Mayer, I.A., Verma, A., Grumbach, I.M., Uddin, S., Lekmine, F., Ravandi, F., Majchrzak, B., Fujita, S., Fish, E.N., Platanias, L.C. (2001) J. Biol Chem., 276, 28570-28577.
41. Budillon, A., Tagliaferri, P., Caraglia, M., Torrisi, M.R., Normanno, N., Iacobelli, S., Palmieri, G., Stoppelli, M.P., Frati, L. and Bianco, A.R. (1991) Cancer Res., 51, 1294-1299.
42. Caraglia, M., Leardi, A., Corradino, S., Ciardiello, F., Budillon, A., Guarrasi, R., Bianco, A.R. and Tagliaferri, P. (1995) Int. J. Cancer, 61, 342-347.
43. Tagliaferri, P., Caraglia, M., Muraro, R., Budillon, A., Pinto, A. and Bianco, A.R. (1994) Anti-Cancer Drugs, 5, 379-393.
44. Caraglia, M., Abbruzzese, A., Leardi, A., Pepe, S., Budillon, A., Baldassarre, G., Selleri, C., De Lorenzo, S., Fabbrocini, A., Giuberti, G., Vitale, G., Lupoli, G., Bianco A.R. and Tagliaferri, P. ( 1999) Cell. Death Differ., 6, 773-780.
45. Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K. and Taniguchi, T. (2003) Nature, 424, 516-523.
46. Yang, C.H., Murti, A., Pfeffer, S.R., Kim J.G., Donner, D.B. and Pfeffer, L.M. (2001) J. Biol. Chem., 17, 13756-13761.
47. Shigeno, M., Nakao, K., Ichikawa, T., Suzuki, K., Kawakami, A., Abiru, S., Miyazoe, S.,Nakagawa, Y., Ishikawa, H., Hamasaki, H., Nakata, K., Ishii N. and Eguchi, K. (2003) Oncogene, 22, 1653-1662.
48. Steiner, T., Junker, U., Henzgen, B., Nuske, K., Durum, S.K. and Schubert, J. (2001) Eur. Urol., 39, 478-483.
49. Caraglia, M., Budillon, A., Vitale, G., Lupoli, G., Tagliaferri, P. and Abbruzzese, A. (2000) Eur. J. Biochem., 267 3919-3936.
50. Meurs, E.F., Chong, K., Galabru, J., Thomas, N.S., Kerr, I.M., Williams, B.R. and Hovanessian, A.G. (1990) Cell, 62, 379-390.
51. Levin, D. and London, I.M. (1978) Proc. Natl. Acad. Sci. USA, 75, 1121-1125.
52. Datta, B. and Datta, R. (1999) Exp. Cell Res., 246 376-383.
53. Chong, K.L., Feng, L., Schappert, K., Meurs, E., Donahue, T,F., Friesen, J.D., Hovanessian, A.G. and Williams, B.R. (1992) EMBO J., 11, 1553-1562.
54. Petryshyn, R., Chen, J.J. and London, I.M. (1984) J. Biol. Chem., 259, 14736-14742.
55. Meurs, E., Galabru, J., Barber, G.N., Katze, M.G. and Hovanessian, A.G. (1993) Proc. Natl. Acad. Sci. USA, 90, 232-236.
56. Koromilas, A.E., Galabru, J., Barber, G.N., Katze, M.G. and Sonenberg, N. (1992) Science, 257, 1685-1689.
57. Zamanian-Daryoush, M., Der, S.D. and Williams, B.R. (1999 Oncogene, 18,315-326.
58. Lee, S.B. and Esteban, M. (1994) Virology, 199, 491-496.
59. Barber, G.N., Thompson, S., Lee, T.G., Strom, T., Jagus, R., Darveau, A. and Katze, M.G. (1994) Proc. Natl. Acad. Sci. USA, 91, 4278-4282.
60. Wu, S., Rehemtulla, A., Gupta, N.K. and Kaufman, R.J. ( 1996) Biochemistry, 35, 8275-8280.
61. Park, H., Davies, M.V., Langland, J.O., Chang, H.W., Nam, Y.S., Tartaglia, J., Paoletti, E., Jacobs, B.L., Kaufman, R.J. and Venkatesan, S. (1994) Proc. Natl. Acad. Sci. USA, 91, 4713-4717.
62. Kibler, K.V., Shors, T., Perkins, K.B., Zeman, C.C., Banaszak, M.P., Biesterfeldt, J., Langland, J.O. and Jacobs, B.L. ( 1997) J. Virol., 71, 1992-2003.
63. Srivastava, S.P., Kumar, K.U. and Kaufman, R.J. (1998) J. Biol. Chem., 273, 2416-2423.
64. Der, S.D., Yang, Y., Weissmann, C. and Williams, B.R.G. ( 1997) Proc. Natl. Acad. Sci. USA, 94, 3279-3283.
65. Jacobs, B.L. and Langland, J.O. (1996) Virology, 219 339-349.
66. Diaz-Guerra, M., Rivas, C. and Esteban, M. (1997) Virology, 236, 354-363.
67. Zhou, A., Paranjape, J., Brown, T.L., Nie, H., Naik, S., Dong, B., Chang, A., Trapp, B., Fairchild, R., Colmenares, C. and Silverman, R.H. (1997) EMBO J., 16, 6355-6363.
68. Rivas, C., Gil, J., Melkova, Z., Esteban, M. and Diaz-Guerra, M. (1998) Virology, 243, 406-414.
69. Yeung, M.C., Liu, J. and Lau, A. (1996) Proc. Natl. Acad. Sci. USA, 93, 12451-12455.
70. Ito, T., Jagus, R. and May, W.S. (1994) Proc. Natl. Acad. Sci. USA, 91, 7453-7459.
71. Gil, J. and Esteban, M. (2000) Apoptosis, 5, 107-114
72. Jenkins, Z.A., Haag, P.G., Johansson, H.E. (2001) Genomics 71, 101-9.
73. Clement, P.M., Henderson, C.A., Jenkins, Z.A., Smit-McBride, Z., Wolff, E.C., Hershey, J.W., Park, M.H., Johansson, H.E. (2003) Eur. J. Biochem. 270, 4254-63;
74. Guan, X.Y., Sham, J.S., Tang, T.C., Fang, Y., Huo, K.K. and Yang, J.M. (2001) Cancer Res. 61, 3806-9.
75. Wolff, E.C., Park, M.H. and Folk, J.E. (1990) J. Biol. Chem., 265, 4793-4799.
76. Park, M.H., Wolff, E.C. and Folk, J.E. (1993) BioFactors, 4, 95-104.
77. Abbruzzese, A., Park, M.H. and Folk, J.E. (1986) J. Biol. Chem., 261, 3085-3089.
78. Hershey, J.W.B. (1991) Annu. Rev. Biochem., 61, 717-755.
79. Park, M.H., Wolff, E.C., Smit-McBride, Z., Hershey, J.W.B. and Folk, J.E. (1991) J. Biol. Chem., 266, 7988-7994.
80. Abbruzzese, A., Isernia, T., Liguori, V. and Beninati, S. ( 1988) In Perspective in polyamine research (Wichtig ed.), pp. 79-84, Perin, A. ed., Milan, Italy.
81. Abbruzzese, A. (1988) J. Neurochem., 50, 695-699.
82. Shnier, J., Schwelberger, H., Smit-McBride, Z., Kang, H.A. and Hershey, J.W.B. (1991) Mol. Cell. Biol., 11, 3105-3114.
83. Abbruzzese, A., Park, M.H., Beninati, S. and Folk, J.E ( 1989) Biochem. Biophys. Acta, 997, 248-255.
84. Beninati, S., Gentile, V., Caraglia, M., Lentini, A., Tagliaferri, P. and Abbruzzese, A. (1998) FEBS Letters, 437, 34-38.
85. Caraglia, M., Passeggio, A., Beninati, S., Leardi, A., Nicolini, L., Improta, S., Pinto, A., Bianco, A.R., Tagliaferri, P. and Abbruzzese, A. (1997) Biochem. J., 324, 737-
86. Mattaj, I.W. and Englmeier L. (1998) Annu. Rev. Biochem., 67, 265-
87. Kjems, J. and Askjaer, P. (2000) Adv. Pharmacol., 48 251-
88. Macara, I.G. (2001) Microbiol. Mol. Biol. Rev., 65 570-
89. Lipowsky, G., Bischoff, F.R., Schwarzmaier, P., Kraft, R., Kostka, S., Hartmann, E., Kutay, U., Gorlich, D. (2000) EMBO J., 19, 4362-4371.
90. Clement, P.M., Hanauske-Abel, H.M., Wolff, E.C., Kleinman, H.K. and Park, M.H. (2002) Int. J. Cancer., 100, 491-8.
91. Lee, Y., Kim, H.K., Park, H.E., Park, M.H., Joe, Y.A. ( 2002) Mol. Cell Biochem.. 237, 69-76.
92. Beadling, C., Guschin, D., Witthuhn, B.A., Ziemiecki, A., Ihle, J.N., Kerr, I.M. and Cantrell, D.A. (1994) EMBO J., 13, 5605-5615.
93. Constantinescu, S. N., Croze, E., Wang, C., Murti, A., Basu, L., Mullersman, J. E. and Pfeffer, L. M. (1994) Proc. Natl. Acad. Sci. USA, 91, 9602-9606.
94. Mullersman, J. E. and Pfeffer, L. M. (1994) Trends Biochem. Sci., 20, 55-56.
95. Pfeffer, L. M., Mullersman, J. E., Pfeffer, S. R., Murti, A., Shi, W. and Yang, C. H. (1997) Science, 276, 1418-1420
96. Yang, C. H., Murti, A. and Pfeffer, L. M. (1998) Proc. Natl. Acad. Sci. USA, 95, 5568-5
97. Franke, T. F., Yang, S.-I., Chan, T. O., Datta, K., Kazlaukas, A., Morrison, D. K., Kaplan, D. R. and Tsichlis, P. N. ( 1995) Cell, 81, 727-736.
98. Burgering, B. M. T. and Coffer, P. J. (1995) Nature, 376, 599-602.
99. Franke, T. F., Kaplan, D. R. and Cantley, L. C. (1997) Cell, 88, 435-437.
100. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y. and Greenberg, M. E. (1997) Cell, 91, 231-241.
101. Cardone, M. H., Roy, N., Stennicke, H. R., Salvesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S. and Reed, J. C. (1998) Science, 282, 1318-1321.
102. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S. anderson, M. J., Arden, K. C., Blenis, J. and Greenberg, M. E. (1999) Cell, 96, 857-868.
103. Navarro, A., Anand-Apte, B., Tanabe, Y., Feldman, G. and Larner, A.C. (2003) J. Leukoc. Biol., 73, 540-
104. Fish, E.N., Uddin, S., Korkmaz, M., Majchrzak, B., Druker, B.J. and Platanias, L.C. (1999) J. Biol. Chem., 274, 571-573.
105. Barahmand-pour, F., Meinke, A., Eilers, A., Gouilleux, F., Groner, B. and Decker T. (1995) FEBS Lett., 360, 29-33.
106. Eilers, A., Baccarini, M., Hipskind, R. A., Schindler, C. and Decker, T. (1994) Mol. Cell. Biol., 14, 1364-1373.
107. Grumbach, I.M., Mayer, I.A., Uddin, S., Lekmine, F., Majchrzak, B., Yamauchi, H., Fujita, S., Druker, B., Fish, E.N. and Platanias L.C. (2001) Br. J. Haematol., 112, 327-336.
108. Meinke, A., Barahmand-Pour, F., Wohrl, S., Stoiber, D. and Decker, T. (1996) Mol. Cell. Biol., 16, 6937-6945.
109. Arora, T., Floyd-Smith, G., Espy, M.J. and Jelinek, D.F. ( 1999) Dissociation between IFN-alpha-induced anti-viral and growth signalling pathways. J. Immunol., 162, 3289-3297.
110. Lund, T.C., Medveczky, M.M. and Medveczky, P.G. (1999) Cell. Immunol., 192: 133-139.
111. Romerio, F., Riva, A. and Zella, D. (2000) Br. J. Cancer, 83, 532-538.
112. Romerio, F. and Zella, D. (2002) FASEB J. 16, 1680-1682.
113. Uddin, S., Sassano, A., Deb, D.K., Verma, A., Majchrzak, B., Rahman, A., Malik, A.B., Fish, E.N. and Platanias, L.C. (2002) J. Biol. Chem., 277, 14408-14
114. Cooney, R.N. (2002) Shock, 17, 83-90.
115. Larsen, L. and Ropke, C. (2002) APMIS, 110, 833-844.
116. Wang, Q., Miyakawa, Y., Fox, N. and Kaushansky, K. (2000 Blood, 96, 2093-2099.
117. David, M., Romero, G., Zhang, Z. Y., Dixon, J. E. and Larner A. C. (1993) J. Biol. Chem., 268, 6593-6599.
118. Igarashi, K., David, M., Finbloom, D. S. and Larner A. C. ( 1993) Mol. Cell. Biol., 13, 1634-1640.
119. Igarashi, K., David, M., Larner, A. C. and Finbloom, D. S. (1993) Mol. Cell. Biol., 13, 3984-3989.
120. David, M., Chen, H. E., Goelz, S., Larner, A. C. and Neel, B. G. (1995) Mol. Cell. Biol., 15, 7050-7058.
121. David, M., Zhou, G., Pine, R., Dixon, J. E. and Larner, A. C. (1996) J. Biol. Chem., 271, 15862-15865.
122. Feng, G. S. and Pawson, T. (1994) Trends Genet., 10 54-58.
123. Neel, B. G. and Tonks, N. K. (1997) Curr. Opin. Cell Biol., 9, 193-204.
124. Lu, X., Qu, C.K., Shi, Z.Q. and Feng, G.S. (1998) Oncogene, 17, 441-448.
125. Shi, Z.Q., Lu, W. and Feng, G.S. (1998) J. Biol. Chem., 273, 4904-4908.
126. Yu, D.H., Qu, C.K., Henegariu, O., Lu, X. and Feng, G.S. ( 1998) J. Biol. Chem., 273, 21125-21131.
127. Simoncic, P.D., Lee-Loy, A., Barber, D.L., Tremblay, M.L. and McGlade, C.J. (2002) Curr. Biol., 12, 446-453.
128. Landolfo, S., Guarini, A., Riera, L., Gariglio, M., Gribaudo, G., Cignetti, A., Cordone, I., Montefusco, E., Mandelli, F. and Foa, R. (2000) Hematol. J., 1, 7-14.
129. Brinckmann, A., Axer, S., Jakschies, D., Dallmann, I., Grosse, J., Patzelt, T., Bernier, T., Emmendoerffer, A. and Atzpodien, J. (2002) Br. J. Cancer., 86, 449-455.
130. Yamauchi, H., Sakai, I., Narumi, H., Takeuchi, K., Soga, S. and Fujita, S. (2001) Intern. Med., 40, 607-612.
131. Wong, L.H., Krauer. K.G., Hatzinisiriou, I., Estcourt, M.J., Hersey, P., Tam, N.D., Edmondson, S., Devenish, R.J. and Ralph, S.J. ( 1997) J. Biol. Chem., 272, 28779-28785.
132. Jackson, D.P., Watling, D., Rogers, N.C., Banks, R.E., Kerr, I.M., Selby, P.J., Patel, P.M. (2003) Melanoma Res., 13, 219-229.
133. Tracey, L., Villuendas, R., Ortiz, P., Dopazo, A., Spiteri, I., Lombardia, L., Rodriguez-Peralto, J.L., Fernandez-Herrera, J., Hernandez, A., Fraga, J., Dominguez, O., Herrero, J., Alonso, M.A., Dopazo, J. and Piris, M.A. (2002) Am. J. Pathol., 161, 1825-1837.
134. Sakai, I., Takeuchi, K., Yamauchi, H., Narumi, H. and Fujita, S. (2002) Blood, 100, 2926-2931.
135. Tian, Z., Shen, X., Feng, H. and Gao, B. (2000) J. Immunol., 165, 3959-3
136. Jan, M.S., Liu, H.S. and Lin, Y.S. (1999) Biochem. Biophys. Res. Commun., 264, 724-729
137. Caraglia, M., Tagliaferri, P., Marra, M., Giuberti, G., Budillon, A., Di Gennaro, E., Pepe, S., Vitale, G., Improta, S., Tassone, P. F., Venuta, S., Bianco, A. R. and Abbruzzese, A. (2003) Cell Death Differ., 10, 218-229.
138. Caraglia, M., Tagliaferri, P., Correale, P., Genua, G., Pepe, S., Pinto, A., Del Vecchio, S., Esposito, G. and Bianco, A.R. (1993 Cancer Immunol. Immunother., 37, 150-156.
139. Caraglia, M., Pinto, A., Correale, P., Zagonel, V., Genua, G., Leardi, A., Pepe, S., Bianco, A.R. and Tagliaferri, P. (1994) Ann. Oncol., 5, 269-276.
140. Budillon, A., Di Gennaro, E., Caraglia, M., Barbarulo, D., Abbruzzese, A. and Tagliaferri, P. (1999) Br. J. Cancer, 81, 1134-1141.
141. Caraglia, M., Marra, M., Giuberti, G., D'Alessandro, A.M., Tassone, P., Venuta, S., Tagliaferri, P. and Abbruzzese, A. (2003) J. Biochem., 133, 757-765.
142. Lee, C.H. and Park, M.H. (2000) Biochem. J., 352, 851-857.
143. Ransohoff, R.M. (1998) N. Engl. J. Med., 338, 616-618.
144. Harvat, B. L., Jetten, A.M. and Seth, P. (1997) Oncogene, 14, 2111-2122.
145. Facchiano, A. M., Stiuso, P., Chiusano, M. L., Caraglia, M., Giuberti, G., Marra, M., Abbruzzese, A. and Colonna, G. (2001) Protein Eng., 14, 881-890.