The p38 MAPK Pathway Mediates the Growth Inhibitory Effects of Interferon-α in BCR-ABL-expressing Cells

Journal of Biological Chemistry

Volumn 276, Issue 30, 2001, Pages 28570-28577

  Mayer, Ingrid A ^a   Verma, Amit ^a   Grumbach, Isabella M ^a   Uddin, Shahab ^a   Lekmine, Fatima ^a   Ravandi, Farhad ^a   Majchrzak, Beata ^b   Fujita, Shigeru ^c   Fish, Eleanor N ^b   Platanias, Leonidas C ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; INTERFERONS;

PHOSPHORYLATION;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BCR ABL PROTEIN; GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RAC1 PROTEIN; RECOMBINANT ALPHA INTERFERON; RECOMBINANT ALPHA2 INTERFERON; SYNAPTOPHYSIN; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; ALPHA INTERFERON; ANDROSTANE DERIVATIVE; ENZYME INHIBITOR; GENISTEIN; IMIDAZOLE DERIVATIVE; MAP KINASE ACTIVATED KINASE 2; MAP KINASE ACTIVATED KINASE 3; MAP-KINASE-ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE; TYROSINE; WORTMANNIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW; CANCER INHIBITION; CANCER RESISTANCE; CHRONIC MYELOID LEUKEMIA; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; GRANULOCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL DIVISION; CELL LINE; CELL STRAIN K 562; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANDROSTADIENES; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME INHIBITORS; FUSION PROTEINS, BCR-ABL; GENISTEIN; HUMANS; IMIDAZOLES; IMMUNOBLOTTING; INTERFERON-ALPHA; K562 CELLS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; TYROSINE;

EID: 0035958901     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011685200     Document Type: Article

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