Interferon-α2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism

British Journal of Cancer

Volumn 83, Issue 4, 2000, Pages 532-538

  Romerio, F ^a   Riva, A ^b   Zella, D ^a  

^a INSTITUTE OF HUMAN VIROLOGY   (United States)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Cellular proliferation; IFN ; MEK ERK pathway

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA2B INTERFERON; GROWTH FACTOR; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN; RECEPTOR; RECOMBINANT ALPHA2B INTERFERON; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; FLAVONOID; HRAS PROTEIN, HUMAN; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN P21; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; CELL DIVISION; CELL LINE; CELL STRAIN U937; CHEMICAL PHENOMENA; DRUG ANTAGONISM; DRUG EFFECT; LEUKEMIA CELL LINE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TIME;

ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TRANSFORMED; DEPRESSION, CHEMICAL; ENZYME INHIBITORS; FLAVONOIDS; HUMANS; INTERFERON ALFA-2B; JURKAT CELLS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); TIME FACTORS; U937 CELLS;

EID: 0034243509     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1263     Document Type: Article

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