-
1
-
-
0033973395
-
Oestrogen and growth factor crosstalk and endocrine insensitivity and acquired resistance in breast cancer
-
Nicholson, R. I., and Gee, J. M. Oestrogen and growth factor crosstalk and endocrine insensitivity and acquired resistance in breast cancer. Br. J. Cancer, 82: 501-513, 2000.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 501-513
-
-
Nicholson, R.I.1
Gee, J.M.2
-
2
-
-
0034790009
-
Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer
-
Nicholson, R. I., Hutcheson, I. R., Harper, M. E., Knowlden, J. M., Barrow, D., McClelland, R. A., Jones, H. E., Wakeling, A. E., and Gee, J. M. Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer. Endocr. Relat. Cancer, 8: 175-182, 2001.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 175-182
-
-
Nicholson, R.I.1
Hutcheson, I.R.2
Harper, M.E.3
Knowlden, J.M.4
Barrow, D.5
McClelland, R.A.6
Jones, H.E.7
Wakeling, A.E.8
Gee, J.M.9
-
3
-
-
0035664874
-
Prospects for combining hormonal and nonhormonal growth factor inhibition
-
discussion 4411s-4412s
-
Wakeling, A. E., Nicholson, R. I., and Gee, J. M. Prospects for combining hormonal and nonhormonal growth factor inhibition. Clin. Cancer Res., 7 (Suppl.): 4350s-4355s; discussion 4411s-4412s, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.SUPPL.
-
-
Wakeling, A.E.1
Nicholson, R.I.2
Gee, J.M.3
-
4
-
-
0028997307
-
HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells
-
Pietras, R. J., Arboleda, J., Reese, D. M., Wongvipat, N., Pegram, M. D., Ramos, L., Gorman, C. M., Parker, M. G., Sliwkowski, M. X., and Slamon, D. J. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene, 10: 2435-2446, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 2435-2446
-
-
Pietras, R.J.1
Arboleda, J.2
Reese, D.M.3
Wongvipat, N.4
Pegram, M.D.5
Ramos, L.6
Gorman, C.M.7
Parker, M.G.8
Sliwkowski, M.X.9
Slamon, D.J.10
-
5
-
-
0030033165
-
The significance of heregulin in breast cancer tumor progression and drug resistance
-
Lupu, R., Cardillo, M., Cho, C., Harris, L., Hijazi, M., Perez, C., Rosenberg, K., Yang, D., and Tang, C. The significance of heregulin in breast cancer tumor progression and drug resistance. Breast Cancer Res. Treat., 38: 57-66, 1996.
-
(1996)
Breast Cancer Res. Treat.
, vol.38
, pp. 57-66
-
-
Lupu, R.1
Cardillo, M.2
Cho, C.3
Harris, L.4
Hijazi, M.5
Perez, C.6
Rosenberg, K.7
Yang, D.8
Tang, C.9
-
6
-
-
0029666144
-
Involvement of heregulin-β2 in the acquisition of the hormone-independent phenotype of breast cancer cells
-
Tang, C. K., Perez, C., Grunt, T., Waibel, C., Cho, C., and Lupu, R. Involvement of heregulin-β2 in the acquisition of the hormone-independent phenotype of breast cancer cells. Cancer Res., 56: 3350-3358, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3350-3358
-
-
Tang, C.K.1
Perez, C.2
Grunt, T.3
Waibel, C.4
Cho, C.5
Lupu, R.6
-
7
-
-
0034987631
-
Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
-
McClelland, R. A., Barrow, D., Madden, T. A., Dutkowski, C. M., Pamment, J., Knowlden, J. M., Gee, J. M., and Nicholson, R. I. Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology, 142: 2776-2788, 2001.
-
(2001)
Endocrinology
, vol.142
, pp. 2776-2788
-
-
McClelland, R.A.1
Barrow, D.2
Madden, T.A.3
Dutkowski, C.M.4
Pamment, J.5
Knowlden, J.M.6
Gee, J.M.7
Nicholson, R.I.8
-
8
-
-
0037373326
-
Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
-
Knowlden, J. M., Hutcheson, I. R., Jones, H. E., Madden, T., Gee, J. M., Harper, M. E., Barrow, D., Wakeling, A. E., and Nicholson, R. I. Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells. Endocrinology, 144: 1032-1044, 2003.
-
(2003)
Endocrinology
, vol.144
, pp. 1032-1044
-
-
Knowlden, J.M.1
Hutcheson, I.R.2
Jones, H.E.3
Madden, T.4
Gee, J.M.5
Harper, M.E.6
Barrow, D.7
Wakeling, A.E.8
Nicholson, R.I.9
-
9
-
-
0031585866
-
Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells
-
Guvakova, M. A., and Surmacz, E. Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells. Exp. Cell Res., 231: 149-162, 1997.
-
(1997)
Exp. Cell Res.
, vol.231
, pp. 149-162
-
-
Guvakova, M.A.1
Surmacz, E.2
-
10
-
-
0035955675
-
Insulin-like growth factor receptor levels are regulated by cell density and by long term estrogen deprivation in MCF7 human breast cancer cells
-
Stephen, R. L., Shaw, L. E., Larsen, C., Corcoran, D., and Darbre, P. D. Insulin-like growth factor receptor levels are regulated by cell density and by long term estrogen deprivation in MCF7 human breast cancer cells. J. Biol. Chem., 276: 40080-40086, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40080-40086
-
-
Stephen, R.L.1
Shaw, L.E.2
Larsen, C.3
Corcoran, D.4
Darbre, P.D.5
-
11
-
-
0027074588
-
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
-
Benz, C. C., Scott, G. K., Sarup, J. C., Johnson, R. M., Tripathy, D., Coronado, E., Shepard, H. M., and Osborne, C. K. Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu. Breast Cancer Res. Treat., 24: 85-95, 1993.
-
(1993)
Breast Cancer Res. Treat.
, vol.24
, pp. 85-95
-
-
Benz, C.C.1
Scott, G.K.2
Sarup, J.C.3
Johnson, R.M.4
Tripathy, D.5
Coronado, E.6
Shepard, H.M.7
Osborne, C.K.8
-
12
-
-
0028928063
-
MCF-7 breast cancer cells overexpressing transfected c-erbB-2 have an in vitro growth advantage in estrogen-depleted conditions and reduced estrogen-dependence and tamoxifen-sensitivity in vivo
-
Liu, Y., el-Ashry, D., Chen, D., Ding, I. Y., and Kern, F. G. MCF-7 breast cancer cells overexpressing transfected c-erbB-2 have an in vitro growth advantage in estrogen-depleted conditions and reduced estrogen-dependence and tamoxifen-sensitivity in vivo. Breast Cancer Res. Treat., 34: 97-117, 1995.
-
(1995)
Breast Cancer Res. Treat.
, vol.34
, pp. 97-117
-
-
Liu, Y.1
El-Ashry, D.2
Chen, D.3
Ding, I.Y.4
Kern, F.G.5
-
13
-
-
0034667395
-
Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells
-
Kurokawa, H., Lenferink, A. E., Simpson, J. F., Pisacane, P. I., Sliwkowski, M. X., Forbes, J. T., and Arteaga, C. L. Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells. Cancer Res., 60: 5887-5894, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 5887-5894
-
-
Kurokawa, H.1
Lenferink, A.E.2
Simpson, J.F.3
Pisacane, P.I.4
Sliwkowski, M.X.5
Forbes, J.T.6
Arteaga, C.L.7
-
14
-
-
1642502703
-
Increased sensitivity of tamoxifen- and fulvestrant-resistant MCF-7 breast cancer cells to the growth inhibitory action of ZD1839 ("Iressa")
-
Amsterdam, The Netherlands: NDDO Research Foundation
-
Hutcheson, I. R., McClelland, R. A., Knowlden, J. M., Barrow, D., Wakeling, A. E., Gee, J. M. W., and Nicholson, R. I. Increased sensitivity of tamoxifen- and fulvestrant-resistant MCF-7 breast cancer cells to the growth inhibitory action of ZD1839 ("Iressa"). In: First International Symposium on Signal Transduction Modulators in Cancer Therapy Proceedings, Amsterdam, The Netherlands: NDDO Research Foundation. Vol. 1, p. 18. 2002.
-
(2002)
First International Symposium on Signal Transduction Modulators in Cancer Therapy Proceedings
, vol.1
, pp. 18
-
-
Hutcheson, I.R.1
McClelland, R.A.2
Knowlden, J.M.3
Barrow, D.4
Wakeling, A.E.5
Gee, J.M.W.6
Nicholson, R.I.7
-
15
-
-
0035036735
-
Estrogen suppression of EGFR expression in breast cancer cells: A possible mechanism to modulate growth
-
Yarden, R. I., Wilson, M. A., and Chrysogelos, S. A. Estrogen suppression of EGFR expression in breast cancer cells: a possible mechanism to modulate growth. J. Cell. Biochem., 81: 232-246, 2001.
-
(2001)
J. Cell. Biochem.
, vol.81
, pp. 232-246
-
-
Yarden, R.I.1
Wilson, M.A.2
Chrysogelos, S.A.3
-
16
-
-
0030795062
-
Antisense estrogen receptor RNA expression increases epidermal growth factor receptor gene expression in breast cancer cells
-
DeFazio, A., Chiew, Y. E., McEvoy, M., Watts, C. K., and Sutherland, R. L. Antisense estrogen receptor RNA expression increases epidermal growth factor receptor gene expression in breast cancer cells. Cell Growth Differ., 8: 903-911, 1997.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 903-911
-
-
DeFazio, A.1
Chiew, Y.E.2
McEvoy, M.3
Watts, C.K.4
Sutherland, R.L.5
-
17
-
-
0026786658
-
Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells
-
van Agthoven, T., van Agthoven, T. L., Portengen, H., Foekens, J. A., and Dorssers, L. C. Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells. Cancer Res., 52: 5082-5088, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 5082-5088
-
-
Van Agthoven, T.1
Van Agthoven, T.L.2
Portengen, H.3
Foekens, J.A.4
Dorssers, L.C.5
-
18
-
-
0027973875
-
Emergence of MCF-7 cells overexpressing a transfected epidermal growth factor receptor (EGFR) under estrogen-depleted conditions: Evidence for a role of EGFR in breast cancer growth and progression
-
Miller, D. L., el-Ashry, D., Cheville, A. L., Liu, Y., McLeskey, S. W., and Kern, F. G. Emergence of MCF-7 cells overexpressing a transfected epidermal growth factor receptor (EGFR) under estrogen-depleted conditions: evidence for a role of EGFR in breast cancer growth and progression. Cell Growth Differ., 5: 1263-1274, 1994.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 1263-1274
-
-
Miller, D.L.1
El-Ashry, D.2
Cheville, A.L.3
Liu, Y.4
McLeskey, S.W.5
Kern, F.G.6
-
19
-
-
0023679801
-
A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo
-
Vickers, P. J., Dickson, R. B., Shoemaker, R., and Cowan, K. H. A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo. Mol. Endocrinol., 2: 886-892, 1988.
-
(1988)
Mol. Endocrinol.
, vol.2
, pp. 886-892
-
-
Vickers, P.J.1
Dickson, R.B.2
Shoemaker, R.3
Cowan, K.H.4
-
20
-
-
0026704233
-
Changes in epidermal growth factor receptor expression and response to ligand associated with acquired tamoxifen resistance of oestrogen independence in the ZR-75-1 human breast cancer cell line
-
Long, B., McKibben, B. M., Lynch, M., and van den Berg, H. W. Changes in epidermal growth factor receptor expression and response to ligand associated with acquired tamoxifen resistance of oestrogen independence in the ZR-75-1 human breast cancer cell line. Br. J. Cancer, 65: 865-869, 1992.
-
(1992)
Br. J. Cancer
, vol.65
, pp. 865-869
-
-
Long, B.1
McKibben, B.M.2
Lynch, M.3
Van Den Berg, H.W.4
-
21
-
-
0028020839
-
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations
-
van Agthoven, T., van Agthoven, T. L., Dekker, A., Foekens, J. A., and Dorssers, L. C. Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations. Mol. Endocrinol., 8: 1474-1483, 1994.
-
(1994)
Mol. Endocrinol.
, vol.8
, pp. 1474-1483
-
-
Van Agthoven, T.1
Van Agthoven, T.L.2
Dekker, A.3
Foekens, J.A.4
Dorssers, L.C.5
-
22
-
-
0030041324
-
Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: The effect of steroid hormones on insulin-like growth factor I receptor expression
-
van den Berg, H. W., Claffie, D., Boylan, M., McKillen, J., Lynch, M., and McKibben, B. Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: the effect of steroid hormones on insulin-like growth factor I receptor expression. Br. J. Cancer, 73: 477-481, 1996.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 477-481
-
-
Van Den Berg, H.W.1
Claffie, D.2
Boylan, M.3
McKillen, J.4
Lynch, M.5
McKibben, B.6
-
23
-
-
0042232592
-
Enhanced ERα ERBB2 and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation
-
Martin, L. A., Farmer, I., Johnston, S. R., Ali, S., Marshall, C. J., and Dowsett, M. Enhanced ERα ERBB2 and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. J. Biol. Chem., 278: 30458-30468, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30458-30468
-
-
Martin, L.A.1
Farmer, I.2
Johnston, S.R.3
Ali, S.4
Marshall, C.J.5
Dowsett, M.6
-
24
-
-
0035919923
-
Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer
-
Gee, J. M., Robertson, J. F., Ellis, I. O., and Nicholson, R. I. Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer. Int. J. Cancer, 4: 247-254, 2001.
-
(2001)
Int. J. Cancer
, vol.4
, pp. 247-254
-
-
Gee, J.M.1
Robertson, J.F.2
Ellis, I.O.3
Nicholson, R.I.4
-
25
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni, A., Brunet, A., West, A. E., Datta, S. R., Takasu, M. A., and Greenberg, M. E. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science (Wash. DC), 286: 1358-1362, 1999.
-
(1999)
Science (Wash. DC)
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
26
-
-
0033580853
-
Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation
-
Gibson, S., Tu, S., Oyer, R., Anderson, S. M., and Johnson, G. L. Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation. J. Biol. Chem., 274: 17612-17618, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17612-17618
-
-
Gibson, S.1
Tu, S.2
Oyer, R.3
Anderson, S.M.4
Johnson, G.L.5
-
27
-
-
0033231188
-
Modulation of cellular apoptotic potential: Contributions to oncogenesis
-
Stambolic, V., Mak, T. W., and Woodgett, J. R. Modulation of cellular apoptotic potential: contributions to oncogenesis. Oncogene, 18: 6094-6103, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 6094-6103
-
-
Stambolic, V.1
Mak, T.W.2
Woodgett, J.R.3
-
28
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: A new model for anti-estrogen resistance
-
Campbell, R. A., Bhat-Nakshatri, P., Patel, N. M., Constantinidou, D., Ali, S., and Nakshatri, H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: a new model for anti-estrogen resistance. J. Biol. Chem., 276: 9817-9824, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
Nakshatri, H.6
-
29
-
-
0032530222
-
Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells
-
Coutts, A. S., and Murphy, L. C. Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer Res., 58: 4071-4074, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4071-4074
-
-
Coutts, A.S.1
Murphy, L.C.2
-
30
-
-
0035798683
-
Kip1 deregulation and antiestrogen resistance in human breast cancer cells
-
Kip1 deregulation and antiestrogen resistance in human breast cancer cells. J. Biol. Chem., 276: 40888-40895, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40888-40895
-
-
Donovan, J.C.1
Milic, A.2
Slingerland, J.M.3
-
31
-
-
0034899503
-
Hyperactivation of MAPK induces loss of ERα expression in breast cancer cells
-
Oh, A. S., Lorant, L. A., Holloway, J. N., Miller, D. L., Kern, F. G., and El-Ashry, D. Hyperactivation of MAPK induces loss of ERα expression in breast cancer cells. Mol. Endocrinol., 15: 1344-1359, 2001.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1344-1359
-
-
Oh, A.S.1
Lorant, L.A.2
Holloway, J.N.3
Miller, D.L.4
Kern, F.G.5
El-Ashry, D.6
-
32
-
-
0037240275
-
ErbB (HER) receptors can abrogate antiestrogen action in human breast cancer by multiple signaling mechanisms
-
Kurokawa, H., and Arteaga, C. L. ErbB (HER) receptors can abrogate antiestrogen action in human breast cancer by multiple signaling mechanisms. Clin. Cancer Res., 9: 511S-515S, 2003.
-
(2003)
Clin. Cancer Res.
, vol.9
-
-
Kurokawa, H.1
Arteaga, C.L.2
-
33
-
-
0033765376
-
Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells
-
Jeng, M. H., Yue, W., Eischeid, A., Wang, J. P., and Santen, R. J. Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells. Breast Cancer Res. Treat., 62: 167-175, 2000.
-
(2000)
Breast Cancer Res. Treat.
, vol.62
, pp. 167-175
-
-
Jeng, M.H.1
Yue, W.2
Eischeid, A.3
Wang, J.P.4
Santen, R.J.5
-
34
-
-
0033821711
-
Stable transfection of protein kinase C α cDNA in hormone-dependent breast cancer cell lines
-
Tonetti, D. A., Chisamore, M. J., Grdina, W., Schurz, H., and Jordan, V. C. Stable transfection of protein kinase C α cDNA in hormone-dependent breast cancer cell lines. Br. J. Cancer, 83: 782-791, 2000.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 782-791
-
-
Tonetti, D.A.1
Chisamore, M.J.2
Grdina, W.3
Schurz, H.4
Jordan, V.C.5
-
35
-
-
0041736202
-
Oestrogen receptor mediated modulation of the EGFR/MAPK pathway in tamoxifen resistant MCF-7 cells
-
Hutcheson, I. R., Knowlden, J. M., Madden, T. A., Barrow, D., Gee, J. M. W., Wakeling, A. E., and Nicholson, R. I. Oestrogen receptor mediated modulation of the EGFR/MAPK pathway in tamoxifen resistant MCF-7 cells. Breast Cancer Res. Treat., 81: 81-93, 2003.
-
(2003)
Breast Cancer Res. Treat.
, vol.81
, pp. 81-93
-
-
Hutcheson, I.R.1
Knowlden, J.M.2
Madden, T.A.3
Barrow, D.4
Gee, J.M.W.5
Wakeling, A.E.6
Nicholson, R.I.7
-
36
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (Wash. DC), 270: 1491-1494, 1995.
-
(1995)
Science (Wash. DC)
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Masushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
-
37
-
-
0029877913
-
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
-
Bunone, G., Briand, P. A., Miksicek, R. J., and Picard, D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J., 15: 2174-2183, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 2174-2183
-
-
Bunone, G.1
Briand, P.A.2
Miksicek, R.J.3
Picard, D.4
-
38
-
-
0027405070
-
Modulation of transcriptional activation by ligand-dependent phosphorylation of the human estrogen receptor A/B region
-
Ali, S., Metzger, D., Bornert, J. M., and Chambon, P. Modulation of transcriptional activation by ligand-dependent phosphorylation of the human estrogen receptor A/B region. EMBO J., 12: 1153-1160, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 1153-1160
-
-
Ali, S.1
Metzger, D.2
Bornert, J.M.3
Chambon, P.4
-
39
-
-
1642502702
-
Increased oestrogen receptor phosphorylation at serine 118 in tamoxifen resistant MCF-7 breast cancer cells
-
Britton, D., Hutcheson, I. R., Barrow, D., Gee, J. M. W., and Nicholson, R. I. Increased oestrogen receptor phosphorylation at serine 118 in tamoxifen resistant MCF-7 breast cancer cells. Biochem. Soc. Trans., 31: P114, 2002.
-
(2002)
Biochem. Soc. Trans.
, vol.31
, pp. 114
-
-
Britton, D.1
Hutcheson, I.R.2
Barrow, D.3
Gee, J.M.W.4
Nicholson, R.I.5
-
40
-
-
0036702132
-
Molecular changes associated with the acquisition of estrogen hypersensitivity in MCF-7 breast cancer cells on long-term estrogen deprivation
-
Chan, C. M., Martin, L. A., Johnston, S. R., Ali, S., and Dowsett, M. Molecular changes associated with the acquisition of estrogen hypersensitivity in MCF-7 breast cancer cells on long-term estrogen deprivation. J. Steroid Biochem. Mol. Biol., 81: 333-341, 2002.
-
(2002)
J. Steroid Biochem. Mol. Biol.
, vol.81
, pp. 333-341
-
-
Chan, C.M.1
Martin, L.A.2
Johnston, S.R.3
Ali, S.4
Dowsett, M.5
-
41
-
-
0033842834
-
Crosstalk between the insulin-like growth factors and estrogens in breast cancer
-
Yee, D., and Lee, A. V. Crosstalk between the insulin-like growth factors and estrogens in breast cancer. J. Mammary Gland Biol. Neoplasia, 5: 107-115, 2000.
-
(2000)
J. Mammary Gland Biol. Neoplasia
, vol.5
, pp. 107-115
-
-
Yee, D.1
Lee, A.V.2
-
42
-
-
0037937417
-
Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells
-
Hamelers, I. H., and Steenbergh, P. H. Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells. Endocr. Relat. Cancer, 10: 331-345, 2003.
-
(2003)
Endocr. Relat. Cancer
, vol.10
, pp. 331-345
-
-
Hamelers, I.H.1
Steenbergh, P.H.2
-
43
-
-
0031031824
-
Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells
-
Lee, A. V., Weng, C. N., Jackson, J. G., and Yee, D. Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. J. Endocrinol., 152: 39-47, 1997.
-
(1997)
J. Endocrinol.
, vol.152
, pp. 39-47
-
-
Lee, A.V.1
Weng, C.N.2
Jackson, J.G.3
Yee, D.4
-
44
-
-
0030849605
-
Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells
-
Guvakova, M. A., and Surmacz, E. Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells. Cancer Res., 57: 2606-2610, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 2606-2610
-
-
Guvakova, M.A.1
Surmacz, E.2
-
45
-
-
0028362024
-
A functional insulin-like growth factor 1 receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor
-
Coppola, D., Ferber, A., Miura, M., Sell, C., D'Ambrosio, C., Rubin, R., and Baserga, R. A functional insulin-like growth factor 1 receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol. Cell. Biol., 14: 4588-4595, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4588-4595
-
-
Coppola, D.1
Ferber, A.2
Miura, M.3
Sell, C.4
D'Ambrosio, C.5
Rubin, R.6
Baserga, R.7
-
46
-
-
0037008761
-
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor
-
Gilmore, A. P., Valentijn, A. J., Wang, P., Ranger, A. M., Bundred, N., O'Hare, M. J., Wakeling, A., Korsmeyer, S. J., and Streuli, C. H. Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor. J. Biol. Chem., 277: 27643-27650, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27643-27650
-
-
Gilmore, A.P.1
Valentijn, A.J.2
Wang, P.3
Ranger, A.M.4
Bundred, N.5
O'Hare, M.J.6
Wakeling, A.7
Korsmeyer, S.J.8
Streuli, C.H.9
-
47
-
-
0034698096
-
Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells
-
Roudabush, F. L., Pierce, K. L., Maudsley, S., Khan, K. D., and Luttrell, L. M. Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. J. Biol. Chem., 275: 22583-22589, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 22583-22589
-
-
Roudabush, F.L.1
Pierce, K.L.2
Maudsley, S.3
Khan, K.D.4
Luttrell, L.M.5
-
48
-
-
85047699864
-
Activation of the TGFα autocrine loop is downstream of IGF-1 receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells
-
Wang, D., Patil, S., Li, W., Humphrey, L. E., Brattain, M. G., and Howell, G. M. Activation of the TGFα autocrine loop is downstream of IGF-1 receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells. Oncogene, 21: 2785-2796, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 2785-2796
-
-
Wang, D.1
Patil, S.2
Li, W.3
Humphrey, L.E.4
Brattain, M.G.5
Howell, G.M.6
-
49
-
-
0042326597
-
Viewpoint: ADAM metalloproteases and EGFR signalling. Breast
-
Gee, J. M. W., and Knowlden, J. M. Viewpoint: ADAM metalloproteases and EGFR signalling. Breast Cancer Res., 5: 223-224, 2003.
-
(2003)
Cancer Res.
, vol.5
, pp. 223-224
-
-
Gee, J.M.W.1
Knowlden, J.M.2
-
50
-
-
0035804218
-
Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells
-
Balana, M. E., Labriola, L., Salatino, M., Movsichoff, F., Peters, G., Charreau, E. H., and Elizalde, P. V. Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells. Oncogene, 20: 34-47, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 34-47
-
-
Balana, M.E.1
Labriola, L.2
Salatino, M.3
Movsichoff, F.4
Peters, G.5
Charreau, E.H.6
Elizalde, P.V.7
-
51
-
-
0027762610
-
Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells
-
Wiseman, L. R., Johnson, M. D., Wakeling, A. E., Lykkesfeldt, A. E., May, F. E., and Westley, B. R. Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells. Eur. J. Cancer, 29A: 2256-2264, 1993.
-
(1993)
Eur. J. Cancer
, vol.29 A
, pp. 2256-2264
-
-
Wiseman, L.R.1
Johnson, M.D.2
Wakeling, A.E.3
Lykkesfeldt, A.E.4
May, F.E.5
Westley, B.R.6
-
52
-
-
0033001742
-
Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line
-
Parisot, J. P., Hu, X. F., DeLuise, M., and Zalcberg, J. R. Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line. Br. J. Cancer, 79: 693-700, 1999.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 693-700
-
-
Parisot, J.P.1
Hu, X.F.2
DeLuise, M.3
Zalcberg, J.R.4
-
53
-
-
0026216808
-
Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells
-
Daly, R. J., Harris, W. H., Wang, D. Y., and Darbre, P. D. Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells. Cell Growth Differ., 2: 457-464, 1991.
-
(1991)
Cell Growth Differ.
, vol.2
, pp. 457-464
-
-
Daly, R.J.1
Harris, W.H.2
Wang, D.Y.3
Darbre, P.D.4
-
54
-
-
0028839154
-
Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation
-
Surmacz, E., and Burgaud, J. L. Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. Clin. Cancer Res., 1: 1429-1436, 1995.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1429-1436
-
-
Surmacz, E.1
Burgaud, J.L.2
-
55
-
-
0033233125
-
Overexpression of insulin-like growth factor II (IGFII) in ZR-75-1 human breast cancer cells: Higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression
-
Abdul-Wahab, K., Corcoran, D., Perachiotti, A., and Darbre, P. D. Overexpression of insulin-like growth factor II (IGFII) in ZR-75-1 human breast cancer cells: higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression. Cell Prolif., 32: 271-287, 1999.
-
(1999)
Cell Prolif.
, vol.32
, pp. 271-287
-
-
Abdul-Wahab, K.1
Corcoran, D.2
Perachiotti, A.3
Darbre, P.D.4
-
56
-
-
1642420739
-
Inhibition of the metastatic potential of tamoxifen-resistant breast cancer cells by gefitinib ("Iressa," AZ1839)
-
Hiscox, S., Wakeling, A. E., and Nicholson, R. I. Inhibition of the metastatic potential of tamoxifen-resistant breast cancer cells by gefitinib ("Iressa," AZ1839). Proc. Am. Assoc. Cancer Res., 44: 4863, 2003.
-
(2003)
Proc. Am. Assoc. Cancer Res.
, vol.44
, pp. 4863
-
-
Hiscox, S.1
Wakeling, A.E.2
Nicholson, R.I.3
-
57
-
-
0038118346
-
A deletion mutant of heregulin increases the sensitivity of breast cancer cells to chemotherapy without promoting tumorigenicity
-
Atlas, E., Bojanowski, K., Mehmi, I., and Lupu, R. A deletion mutant of heregulin increases the sensitivity of breast cancer cells to chemotherapy without promoting tumorigenicity. Oncogene, 22: 3441-3451, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 3441-3451
-
-
Atlas, E.1
Bojanowski, K.2
Mehmi, I.3
Lupu, R.4
-
58
-
-
0027400813
-
The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells
-
Thompson, E. W., Brunner, N., Torri, J., Johnson, M. D., Boulay, V., Wright, A., Lippman, M. E., Steeg, P. S., and Clarke, R. The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells. Clin. Exp. Metastasis, 11: 15-26, 1993.
-
(1993)
Clin. Exp. Metastasis
, vol.11
, pp. 15-26
-
-
Thompson, E.W.1
Brunner, N.2
Torri, J.3
Johnson, M.D.4
Boulay, V.5
Wright, A.6
Lippman, M.E.7
Steeg, P.S.8
Clarke, R.9
-
59
-
-
0032731892
-
Tumor invasion: Role of growth factor-induced cell motility
-
Wells, A. Tumor invasion: role of growth factor-induced cell motility. Adv. Cancer Res., 78: 31-101, 2000.
-
(2000)
Adv. Cancer Res.
, vol.78
, pp. 31-101
-
-
Wells, A.1
-
60
-
-
0345300537
-
Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pakl pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa)
-
Barnes, C. J., Bagheri-Yarmand, R., Mandal, M., Yang, Z., Clayman, G. L., Hong, W. K., and Kumar, R. Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pakl pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa). Mol. Cancer Ther., 2: 345-351, 2003.
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 345-351
-
-
Barnes, C.J.1
Bagheri-Yarmand, R.2
Mandal, M.3
Yang, Z.4
Clayman, G.L.5
Hong, W.K.6
Kumar, R.7
-
61
-
-
0036361439
-
ZD1839 (Iressa™): For more than just non-small cell lung cancer
-
Ranson, M. ZD1839 (Iressa™): for more than just non-small cell lung cancer. Oncologist, 7: 16-24, 2002.
-
(2002)
Oncologist
, vol.7
, pp. 16-24
-
-
Ranson, M.1
-
62
-
-
0037295398
-
Studies with ZD1839 in preclinical models
-
Sirotnak, F. M. Studies with ZD1839 in preclinical models. Semin. Oncol., 30 (Suppl. 1): 12-20, 2003.
-
(2003)
Semin. Oncol.
, vol.30
, Issue.SUPPL. 1
, pp. 12-20
-
-
Sirotnak, F.M.1
-
63
-
-
0036016095
-
ZD1839: Targeting the epidermal growth factor receptor in cancer therapy
-
Herbst, R. S. ZD1839: targeting the epidermal growth factor receptor in cancer therapy. Expert Opin. Investig. Drugs, 11: 837-849, 2002.
-
(2002)
Expert Opin. Investig. Drugs
, vol.11
, pp. 837-849
-
-
Herbst, R.S.1
-
64
-
-
0037109014
-
ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
Wakeling, A. E., Guy, S. P., Woodburn, J. R., Ashton, S. E., Curry, B. J., Barker, A. J., and Gibson, K. H. ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res., 62: 5749-5754, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
Ashton, S.E.4
Curry, B.J.5
Barker, A.J.6
Gibson, K.H.7
-
65
-
-
0027309375
-
Relationship between EGF-R, c-erbB-2 protein expression and Ki-67 immunostaining in breast cancer and hormone sensitivity
-
Nicholson, R. I., McClelland, R. A., Finlay, P., Eaton, C. L., Gullick, W. J., Dixon, A. R., et al. Relationship between EGF-R, c-erbB-2 protein expression and Ki-67 immunostaining in breast cancer and hormone sensitivity. Eur. J. Cancer, 29A: 1018-1023, 1993.
-
(1993)
Eur. J. Cancer
, vol.29 A
, pp. 1018-1023
-
-
Nicholson, R.I.1
McClelland, R.A.2
Finlay, P.3
Eaton, C.L.4
Gullick, W.J.5
Dixon, A.R.6
-
66
-
-
0028293921
-
Epidermal growth factor receptor expression in breast cancer: Association with response to endocrine therapy
-
Nicholson, R. I., McClelland, R. A., Gee, J. M., Manning, D. L., Cannon, P., Robertson, J. F., Ellis, I. O., and Blamey, R. W. Epidermal growth factor receptor expression in breast cancer: association with response to endocrine therapy. Breast Cancer Res. Treat., 29: 117-125, 1994.
-
(1994)
Breast Cancer Res. Treat.
, vol.29
, pp. 117-125
-
-
Nicholson, R.I.1
McClelland, R.A.2
Gee, J.M.3
Manning, D.L.4
Cannon, P.5
Robertson, J.F.6
Ellis, I.O.7
Blamey, R.W.8
-
67
-
-
0028176880
-
Transforming growth factor-α and endocrine sensitivity in breast cancer
-
Nicholson, R. I., McClelland, R. A., Gee, J. M., Manning, D. L., Cannon, P., Robertson, J. F., Ellis, I. O., and Blamey, R. W. Transforming growth factor-α and endocrine sensitivity in breast cancer. Cancer Res., 54: 1684-1689, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1684-1689
-
-
Nicholson, R.I.1
McClelland, R.A.2
Gee, J.M.3
Manning, D.L.4
Cannon, P.5
Robertson, J.F.6
Ellis, I.O.7
Blamey, R.W.8
-
68
-
-
0034778447
-
EGFR cancer prognosis
-
Nicholson, R. I., Gee, J. M., and Harper, M. E. EGFR and cancer prognosis. Eur. J. Cancer, 37: 9-15, 2001.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 9-15
-
-
Nicholson, R.I.1
Gee, J.M.2
Harper, M.E.3
-
69
-
-
0028212870
-
The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: Results of a 10 year follow-up study
-
Klijn, J. G., Look, M. P., Portengen, H., Alexieva-Figusch, J., van Putten, W. L., and Foekens, J. A. The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: results of a 10 year follow-up study. Breast Cancer Res. Treat., 29: 73-83, 1994.
-
(1994)
Breast Cancer Res. Treat.
, vol.29
, pp. 73-83
-
-
Klijn, J.G.1
Look, M.P.2
Portengen, H.3
Alexieva-Figusch, J.4
Van Putten, W.L.5
Foekens, J.A.6
-
70
-
-
0034691562
-
Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients
-
Mueller, H., Flury, N., Eppenberger-Castori, S., Kueng, W., David, F., and Eppenberger, U. Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients. Int. J. Cancer, 89: 384-388, 2000.
-
(2000)
Int. J. Cancer
, vol.89
, pp. 384-388
-
-
Mueller, H.1
Flury, N.2
Eppenberger-Castori, S.3
Kueng, W.4
David, F.5
Eppenberger, U.6
-
71
-
-
0036284423
-
Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression
-
Adeyinka, A., Nui, Y., Cherlet, T., Snell, L., Watson, P. H., and Murphy, L. C. Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression. Clin. Cancer Res., 8: 1747-1753, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1747-1753
-
-
Adeyinka, A.1
Nui, Y.2
Cherlet, T.3
Snell, L.4
Watson, P.H.5
Murphy, L.C.6
-
72
-
-
1642461800
-
Clinical response and resistance to SERMS
-
J. F. R. Robertson, R. I. Nicholson, and D. F. Hayes (eds.). London: Martin Dunitz Ltd.
-
Gee, J. M. W., Madden, T. A., Robertson, J. F. R., and Nicholson, R. I. Clinical response and resistance to SERMS. In: J. F. R. Robertson, R. I. Nicholson, and D. F. Hayes (eds.), Endocrine Therapy in Breast Cancer, pp. 155-190. London: Martin Dunitz Ltd., 2002.
-
(2002)
Endocrine Therapy in Breast Cancer
, pp. 155-190
-
-
Gee, J.M.W.1
Madden, T.A.2
Robertson, J.F.R.3
Nicholson, R.I.4
-
73
-
-
18244391514
-
Southeast Sweden Breast Cancer Group: Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
-
Perez-Tenorio, G., and Stal, O. Southeast Sweden Breast Cancer Group: activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br. J. Cancer, 86: 540-545, 2002.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 540-545
-
-
Perez-Tenorio, G.1
Stal, O.2
-
74
-
-
0038146847
-
Elevated protein kinase C a expression may be predictive of tamoxifen treatment failure
-
Tonetti, D. A., Morrow, M., Kidwai, N., Gupta, A., and Badve, S. Elevated protein kinase C a expression may be predictive of tamoxifen treatment failure. Br. J. Cancer, 88: 1400-1402, 2003.
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1400-1402
-
-
Tonetti, D.A.1
Morrow, M.2
Kidwai, N.3
Gupta, A.4
Badve, S.5
-
75
-
-
0042804495
-
Gefitinib (ZD1839) is active in acquired tamoxifen (TAM)-resistant oestrogen receptor (ER)-positive and ER-negative breast cancer: Results from a Phase II study
-
Robertson, J. F. R., Gutteridge, E., Cheung, K. L., Owers, R., Koehler, M., Hamilton, L., Gee, J., and Nicholson, R. I. Gefitinib (ZD1839) is active in acquired tamoxifen (TAM)-resistant oestrogen receptor (ER)-positive and ER-negative breast cancer: results from a Phase II study. Proc. Am. Soc. Clin. Oncol., 22: 7, 2003.
-
(2003)
Proc. Am. Soc. Clin. Oncol.
, vol.22
, pp. 7
-
-
Robertson, J.F.R.1
Gutteridge, E.2
Cheung, K.L.3
Owers, R.4
Koehler, M.5
Hamilton, L.6
Gee, J.7
Nicholson, R.I.8
-
76
-
-
0031684721
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
-
Ross, J. S., and Fletcher, J. A. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist, 3: 237-252, 1998.
-
(1998)
Oncologist
, vol.3
, pp. 237-252
-
-
Ross, J.S.1
Fletcher, J.A.2
-
77
-
-
0032982818
-
Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancer
-
Houston, S. J., Plunkett, T. A., Barnes, D. M., Smith, P., Rubens, R. D., and Miles, D. W. Overexpression of c-erbB2 is an independent marker of resistance to endocrine therapy in advanced breast cancer. Br. J. Cancer, 79: 1220-1226, 1999.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1220-1226
-
-
Houston, S.J.1
Plunkett, T.A.2
Barnes, D.M.3
Smith, P.4
Rubens, R.D.5
Miles, D.W.6
-
78
-
-
0034473776
-
The role of HER-2 expression in predicting response to therapy in breast cancer
-
Mass, R. The role of HER-2 expression in predicting response to therapy in breast cancer. Semin. Oncol., 27 (Suppl. 11): 46-52, 2000.
-
(2000)
Semin. Oncol.
, vol.27
, Issue.SUPPL. 11
, pp. 46-52
-
-
Mass, R.1
-
79
-
-
0034794636
-
Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer
-
Dowsett, M. Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer. Endocr. Relat. Cancer, 8: 191-195, 2001.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 191-195
-
-
Dowsett, M.1
-
80
-
-
0035576786
-
HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer
-
Dowsett, M., Harper-Wynne, C., Boeddinghaus, I., Salter, J., Hills, M., Dixon, M., Ebbs, S., Gui, G., Sacks, N., and Smith, I. HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer. Cancer Res., 61: 8452-8458, 2001b.
-
(2001)
Cancer Res.
, vol.61
, pp. 8452-8458
-
-
Dowsett, M.1
Harper-Wynne, C.2
Boeddinghaus, I.3
Salter, J.4
Hills, M.5
Dixon, M.6
Ebbs, S.7
Gui, G.8
Sacks, N.9
Smith, I.10
-
81
-
-
0029800395
-
C-erb-b2/int-2 amplification appears faster in breast-cancer patients receiving second-line endocrine treatment
-
Lonn, U., Lonn, S., Ingelman-Sundberg, H., Nilsson, B., and Stenkvist, B. C-erb-b2/int-2 amplification appears faster in breast-cancer patients receiving second-line endocrine treatment. Int. J. Cancer, 69: 273-277, 1996.
-
(1996)
Int. J. Cancer
, vol.69
, pp. 273-277
-
-
Lonn, U.1
Lonn, S.2
Ingelman-Sundberg, H.3
Nilsson, B.4
Stenkvist, B.5
-
82
-
-
0242724820
-
Molecular changes in tamoxifen-relapsed breast cancer: Relationship between ER, HER2 and P38-MAP-kinase
-
Dowsett, M., Gutierrez, C., Mohsin, S., Schiff, R., Detre, S., Johnston, S., and Osborne, C. K. Molecular changes in tamoxifen-relapsed breast cancer: relationship between ER, HER2 and P38-MAP-kinase. Proc. Am. Soc. Clin. Oncol., 22: 3, 2003.
-
(2003)
Proc. Am. Soc. Clin. Oncol.
, vol.22
, pp. 3
-
-
Dowsett, M.1
Gutierrez, C.2
Mohsin, S.3
Schiff, R.4
Detre, S.5
Johnston, S.6
Osborne, C.K.7
-
83
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel, C. L., Cobleigh, M. A., Tripathy, D., Gutheil, J. C., Harris, L. N., Fehrenbacher, L., Slamon, D. J., Murphy, M., Novotny, W. F., Burchmore, M., Shak, S., Stewart, S. J., and Press, M. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol., 20: 719-726, 2002.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
84
-
-
0031015394
-
Enhanced anti-proliferative activity of the combination of tamoxifen plus HER-2-neu antibody
-
Witters, L. M., Kumar, R., Chinchilli, V. M., and Lipton, A. Enhanced anti-proliferative activity of the combination of tamoxifen plus HER-2-neu antibody. Breast Cancer Res. Treat., 42: 1-5, 1997.
-
(1997)
Breast Cancer Res. Treat.
, vol.42
, pp. 1-5
-
-
Witters, L.M.1
Kumar, R.2
Chinchilli, V.M.3
Lipton, A.4
-
85
-
-
0036835014
-
Restoration of estrogen responsiveness by blocking the HER-2/neu pathway
-
Witters, L., Engle, L., and Lipton, A. Restoration of estrogen responsiveness by blocking the HER-2/neu pathway. Oncol. Rep., 9: 1163-1166, 2002.
-
(2002)
Oncol. Rep.
, vol.9
, pp. 1163-1166
-
-
Witters, L.1
Engle, L.2
Lipton, A.3
-
86
-
-
0028233617
-
The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients
-
Railo, M. J., von Smitten, K., and Pekonen, F. The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients. Eur. J. Cancer, 30A: 307-311, 1994.
-
(1994)
Eur. J. Cancer
, vol.30 A
, pp. 307-311
-
-
Railo, M.J.1
Von Smitten, K.2
Pekonen, F.3
-
87
-
-
0025636494
-
Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors
-
Peyrat, J. P., Bonneterre, J., Vennin, P. H., Jammes, H., Beuscart, R., Hecquet, B., Djiane, J., Lefebvre, J., and Demaille, A. Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors. J. Steroid Biochem. Mol. Biol., 37: 823-827, 1990.
-
(1990)
J. Steroid Biochem. Mol. Biol.
, vol.37
, pp. 823-827
-
-
Peyrat, J.P.1
Bonneterre, J.2
Vennin, P.H.3
Jammes, H.4
Beuscart, R.5
Hecquet, B.6
Djiane, J.7
Lefebvre, J.8
Demaille, A.9
-
88
-
-
0034693680
-
Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer
-
Schnarr, B., Strunz, K., Ohsam, J., Benner, A., Wacker, J., and Mayer, D. Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer. Int. J. Cancer, 89: 506-513, 2000.
-
(2000)
Int. J. Cancer
, vol.89
, pp. 506-513
-
-
Schnarr, B.1
Strunz, K.2
Ohsam, J.3
Benner, A.4
Wacker, J.5
Mayer, D.6
-
89
-
-
0031051830
-
Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: Correlation with clinical parameters and disease-free survival
-
Rocha, R. L., Hilsenbeck, S. G., Jackson, J. G., VanDenBerg, C. L., Weng, C., Lee, A. V., and Yee, D. Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival. Clin. Cancer Res., 3: 103-109, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 103-109
-
-
Rocha, R.L.1
Hilsenbeck, S.G.2
Jackson, J.G.3
VanDenBerg, C.L.4
Weng, C.5
Lee, A.V.6
Yee, D.7
-
90
-
-
0033618371
-
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
-
Nakatani, K., Thompson, D. A., Barthel, A., Sakaue, H., Liu, W., Weigel, R. J., and Roth, R. A. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J. Biol. Chem., 274: 21528-21532, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21528-21532
-
-
Nakatani, K.1
Thompson, D.A.2
Barthel, A.3
Sakaue, H.4
Liu, W.5
Weigel, R.J.6
Roth, R.A.7
-
91
-
-
16944364325
-
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation
-
Turner, B. C., Haffty, B. G., Narayanan, L., Yuan, J., Havre, P. A., Gumbs, A. A., Kaplan, L., Burgaud, J. L., Carter, D., Baserga, R., and Glazer, P. M. Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res., 57: 3079-3083, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3079-3083
-
-
Turner, B.C.1
Haffty, B.G.2
Narayanan, L.3
Yuan, J.4
Havre, P.A.5
Gumbs, A.A.6
Kaplan, L.7
Burgaud, J.L.8
Carter, D.9
Baserga, R.10
Glazer, P.M.11
-
92
-
-
0035915283
-
Unraveling resistance to trastuzumab (Herceptin): Insulin-like growth factor-I receptor, a new suspect
-
Albanell, J., and Baselga, J. Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect. J. Natl. Cancer Inst. (Bethesda), 93: 1830-1832, 2001.
-
(2001)
J. Natl. Cancer Inst. (Bethesda)
, vol.93
, pp. 1830-1832
-
-
Albanell, J.1
Baselga, J.2
-
93
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu, Y., Zi, X., Zhao, Y., Mascarenhas, D., and Pollak, M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J. Natl. Cancer Inst. (Bethesda), 93: 1852-1857, 2001,
-
(2001)
J. Natl. Cancer Inst. (Bethesda)
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
Mascarenhas, D.4
Pollak, M.5
-
94
-
-
1142293604
-
Phase tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer
-
Baselga, J., Albanell, J., Ruiz, A., Lluch, A., Gascon, P., Gonzalez, S., Guillen, V., Sauleda, S., Averbuch, S., and Rojo, F. Phase II and tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer. Proc. Am. Soc. Clin. Oncol., 22: 191, 2003.
-
(2003)
Proc. Am. Soc. Clin. Oncol.
, vol.22
, pp. 191
-
-
Baselga, J.1
Albanell, J.2
Ruiz, A.3
Lluch, A.4
Gascon, P.5
Gonzalez, S.6
Guillen, V.7
Sauleda, S.8
Averbuch, S.9
Rojo II, F.10
-
95
-
-
85047699134
-
Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells
-
Scotlandi, K., Maini, C., Manara, M. C., Benini, S., Serra, M., Cerisano, V., Strammiello, R., Baldini, N., Lollini, P. L., Nanni, P., Nicoletti, G., and Picci, P. Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells. Cancer Gene Ther., 9: 296-307, 2002.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 296-307
-
-
Scotlandi, K.1
Maini, C.2
Manara, M.C.3
Benini, S.4
Serra, M.5
Cerisano, V.6
Strammiello, R.7
Baldini, N.8
Lollini, P.L.9
Nanni, P.10
Nicoletti, G.11
Picci, P.12
-
96
-
-
0037616593
-
Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counter-acts the antitumor action of EGFR tyrosine kinase inhibitors
-
Bianco, R., Shin, I., Ritter, C. A., Yakes, F. M., Basso, A., Rosen, N., Tsurutani, J., Dennis, P. A., Mills, G. B., and Arteaga, C. L. Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counter-acts the antitumor action of EGFR tyrosine kinase inhibitors. Oncogene, 22: 2812-2822, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 2812-2822
-
-
Bianco, R.1
Shin, I.2
Ritter, C.A.3
Yakes, F.M.4
Basso, A.5
Rosen, N.6
Tsurutani, J.7
Dennis, P.A.8
Mills, G.B.9
Arteaga, C.L.10
-
97
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark, A. S., West, K., Streicher, S., and Dennis, P. A. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol. Cancer Ther., 1: 707-717, 2002.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
98
-
-
0037443030
-
Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCδ promotes cellular survival and chemotherapeutic resistance
-
Clark, A. S., West, K. A., Blumberg, P. M., and Dennis, P. A. Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCδ promotes cellular survival and chemotherapeutic resistance. Cancer Res., 63: 780-786, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 780-786
-
-
Clark, A.S.1
West, K.A.2
Blumberg, P.M.3
Dennis, P.A.4
-
99
-
-
0037099532
-
Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
-
Yakes, F. M., Chinratanalab, W., Ritter, C. A., King, W., Seelig, S., and Arteaga, C. L. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res., 62: 4132-4141, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 4132-4141
-
-
Yakes, F.M.1
Chinratanalab, W.2
Ritter, C.A.3
King, W.4
Seelig, S.5
Arteaga, C.L.6
-
100
-
-
0036963448
-
Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells
-
Camirand, A., Lu, Y., and Pollak, M. Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells. Med. Sci. Monit., 8: BR521-BR526, 2002.
-
(2002)
Med. Sci. Monit.
, vol.8
-
-
Camirand, A.1
Lu, Y.2
Pollak, M.3
-
101
-
-
9144249851
-
ZD1839 ("Iressa") improves the antitumour activity of tamoxifen ("Nolvadex") and ICI 182,780 ("Faslodex") in antihormone responsive breast cancer
-
Gee, J. M. W., Harper, M. E., Hutcheson, I. R., Madden, T. A., Barrow, D. Knowlden, J. M., McClelland, R. A., Jordan, N., Wakeling, A. E., and Nicholson, R. I. ZD1839 ("Iressa") improves the antitumour activity of tamoxifen ("Nolvadex") and ICI 182,780 ("Faslodex") in antihormone responsive breast cancer. Eur. J. Cancer, 38 (Suppl. 7): 59, 2002.
-
(2002)
Eur. J. Cancer
, vol.38
, Issue.SUPPL. 7
, pp. 59
-
-
Gee, J.M.W.1
Harper, M.E.2
Hutcheson, I.R.3
Madden, T.A.4
Barrow, D.5
Knowlden, J.M.6
McClelland, R.A.7
Jordan, N.8
Wakeling, A.E.9
Nicholson, R.I.10
-
102
-
-
0242721012
-
The anti-EGFR agent gefitinib (ZD1839/Iressa™) improves anti-hormone response and prevents development of resistance in breast cancer in vitro
-
Gee, J. M. W., Harper, M. E., Hutcheson, I. R., Madden, T. A., Barrow, D., Knowlden, J. M., McClelland, R. A., Jordan, N., Wakeling, A. E., and Nicholson, R. I. The anti-EGFR agent gefitinib (ZD1839/Iressa™) improves anti-hormone response and prevents development of resistance in breast cancer in vitro. Endocrinology, 144: 5105-5117, 2003.
-
(2003)
Endocrinology
, vol.144
, pp. 5105-5117
-
-
Gee, J.M.W.1
Harper, M.E.2
Hutcheson, I.R.3
Madden, T.A.4
Barrow, D.5
Knowlden, J.M.6
McClelland, R.A.7
Jordan, N.8
Wakeling, A.E.9
Nicholson, R.I.10
-
103
-
-
0000897357
-
Inhibition of epidermal growth factor/HER2 receptor signalling using ZD1839 ("Iressa") restores tamoxifen sensitivity and delays resistance to oestrogen deprivation in HER2-overexpressing breast tumors
-
Massarweh, S., Shou, J., Mohsin, S. K., Ge, M., Wakeling, A. E., Osborne, C. K., and Schiff, R. Inhibition of epidermal growth factor/HER2 receptor signalling using ZD1839 ("Iressa") restores tamoxifen sensitivity and delays resistance to oestrogen deprivation in HER2-overexpressing breast tumors. Proc. Am. Soc. Clin. Oncol., 21: 33, 2002.
-
(2002)
Proc. Am. Soc. Clin. Oncol.
, vol.21
, pp. 33
-
-
Massarweh, S.1
Shou, J.2
Mohsin, S.K.3
Ge, M.4
Wakeling, A.E.5
Osborne, C.K.6
Schiff, R.7
|