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Volumn 63, Issue 4, 2003, Pages 780-786

Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCδ promotes cellular survival and chemotherapeutic resistance

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; CALPHOSTIN C; CHELERYTHRINE; CISPLATIN; DOCETAXEL; GEMCITABINE; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; ROTTLERIN; TRASTUZUMAB;

EID: 0037443030     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (160)

References (36)
  • 1
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • Brognard, J., Clark, A. S., Ni, Y., and Dennis, P. A. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res., 61: 3986-3997, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3    Dennis, P.A.4
  • 2
    • 0036719080 scopus 로고    scopus 로고
    • Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants
    • Brognard, J., and Dennis, P. A. Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants. Cell Death Differ., 9: 893-904, 2002.
    • (2002) Cell Death Differ. , vol.9 , pp. 893-904
    • Brognard, J.1    Dennis, P.A.2
  • 3
    • 0032585532 scopus 로고    scopus 로고
    • Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
    • Dutil, E. M., Toker, A., and Newton, A. C. Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1). Curr. Biol., 8: 1366-1375, 1998.
    • (1998) Curr. Biol. , vol.8 , pp. 1366-1375
    • Dutil, E.M.1    Toker, A.2    Newton, A.C.3
  • 4
    • 0033547434 scopus 로고    scopus 로고
    • Protein kinase C-α overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal
    • Li, W., Zhang, J., Flechner, L., Hyun, T., Yam, A., Franke, T. F., and Pierce, J. H. Protein kinase C-α overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal. Oncogene, 18: 6564-6572, 1999.
    • (1999) Oncogene , vol.18 , pp. 6564-6572
    • Li, W.1    Zhang, J.2    Flechner, L.3    Hyun, T.4    Yam, A.5    Franke, T.F.6    Pierce, J.H.7
  • 6
    • 0033082319 scopus 로고    scopus 로고
    • Protein kinase C δ
    • Gschwendt, M. Protein kinase C δ Eur. J. Biochem., 259: 555-564, 1999.
    • (1999) Eur. J. Biochem. , vol.259 , pp. 555-564
    • Gschwendt, M.1
  • 7
    • 0033520995 scopus 로고    scopus 로고
    • Mammalian TOR controls one of two kinase pathways acting upon nPKCδ and nPKCε
    • Parekh, D., Ziegler, W., Yonezawa, K., Hara, K., and Parker, P. J. Mammalian TOR controls one of two kinase pathways acting upon nPKCδ and nPKCε. J. Biol. Chem., 274: 34758-34764, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 34758-34764
    • Parekh, D.1    Ziegler, W.2    Yonezawa, K.3    Hara, K.4    Parker, P.J.5
  • 10
    • 0028670203 scopus 로고
    • The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C ζ
    • Konishi, H., Kuroda, S., and Kikkawa, U. The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C ζ. Biochem. Biophys. Res. Commun., 205: 1770-1775, 1994.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1770-1775
    • Konishi, H.1    Kuroda, S.2    Kikkawa, U.3
  • 12
    • 0035992301 scopus 로고    scopus 로고
    • Phase 1 trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-β-D-arabinofuranosylcytosine in patients with refractory acute leukemia
    • Cragg, L. H., Andreeff, M., Feldman, E., Roberts, J., Murgo, A., Winning, M., Tombes, M. B., Roboz, G., Kramer, L., and Grant, S. Phase 1 trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-β-D-arabinofuranosylcytosine in patients with refractory acute leukemia. Clin. Cancer Res., 8: 2123-2133, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2123-2133
    • Cragg, L.H.1    Andreeff, M.2    Feldman, E.3    Roberts, J.4    Murgo, A.5    Winning, M.6    Tombes, M.B.7    Roboz, G.8    Kramer, L.9    Grant, S.10
  • 13
    • 0036667939 scopus 로고    scopus 로고
    • The clinical development of the bryostatins
    • Clamp, A., and Jayson, G. C. The clinical development of the bryostatins. Anticancer Drugs, 13: 673-683, 2002.
    • (2002) Anticancer Drugs , vol.13 , pp. 673-683
    • Clamp, A.1    Jayson, G.C.2
  • 14
    • 0023944920 scopus 로고
    • Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes
    • Reddel, R. R., Ke, Y., Gerwin, B. I., McMenamin, M. G., Lechner, J. F., Su, R. T., Brash, D. E., Park, J. B., Rhim, J. S., and Harris, C. C. Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res., 48: 1904-1909, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1904-1909
    • Reddel, R.R.1    Ke, Y.2    Gerwin, B.I.3    McMenamin, M.G.4    Lechner, J.F.5    Su, R.T.6    Brash, D.E.7    Park, J.B.8    Rhim, J.S.9    Harris, C.C.10
  • 15
    • 0035413601 scopus 로고    scopus 로고
    • Protein kinase C: Structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
    • Newton, A. C. Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem. Rev., 101: 2353-2364, 2001.
    • (2001) Chem. Rev. , vol.101 , pp. 2353-2364
    • Newton, A.C.1
  • 16
    • 0030762437 scopus 로고    scopus 로고
    • The potential for isoenzyme-selective modulation of protein kinase C
    • Hofmann, J. The potential for isoenzyme-selective modulation of protein kinase C. FASEB J., 11: 649-669, 1997.
    • (1997) FASEB J. , vol.11 , pp. 649-669
    • Hofmann, J.1
  • 18
    • 0029956761 scopus 로고    scopus 로고
    • Characterization of the protein kinase C signal transduction pathway in cisplatin-sensitive and -resistant human small cell lung carcinoma cells
    • Basu, A., Weixel, K., and Saijo, N. Characterization of the protein kinase C signal transduction pathway in cisplatin-sensitive and -resistant human small cell lung carcinoma cells. Cell Growth Differ., 7: 1507-1512, 1996.
    • (1996) Cell Growth Differ. , vol.7 , pp. 1507-1512
    • Basu, A.1    Weixel, K.2    Saijo, N.3
  • 19
    • 0034533061 scopus 로고    scopus 로고
    • Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells
    • Mao, M., Fang, X., Lu, Y., Lapushin, R., Bast, R. C., Jr., and Mills, G. B. Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells. Biochem. J., 352: 475-482, 2000.
    • (2000) Biochem. J. , vol.352 , pp. 475-482
    • Mao, M.1    Fang, X.2    Lu, Y.3    Lapushin, R.4    Bast R.C., Jr.5    Mills, G.B.6
  • 20
    • 0035866371 scopus 로고    scopus 로고
    • Elevated protein kinase C βII is an early promotive event in colon carcinogenesis
    • Gokmen-Polar, Y., Murray, N. R., Velasco, M. A., Gatalica, Z., and Fields, A. P. Elevated protein kinase C βII is an early promotive event in colon carcinogenesis. Cancer Res., 61: 1375-1381, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 1375-1381
    • Gokmen-Polar, Y.1    Murray, N.R.2    Velasco, M.A.3    Gatalica, Z.4    Fields, A.P.5
  • 21
    • 0032851481 scopus 로고    scopus 로고
    • Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells
    • Weller, S. G., Klein, I. K., Penington, R. C., and Karnes, W. E., Jr. Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells. Gastroenterology, 117: 848-857, 1999.
    • (1999) Gastroenterology , vol.117 , pp. 848-857
    • Weller, S.G.1    Klein, I.K.2    Penington, R.C.3    Karnes W.E., Jr.4
  • 23
    • 0035976977 scopus 로고    scopus 로고
    • The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase
    • Sonnenburg, E. D., Gao, T., and Newton, A. C. The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase. J. Biol. Chem., 276: 45289-45297, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45289-45297
    • Sonnenburg, E.D.1    Gao, T.2    Newton, A.C.3
  • 24
    • 84989446834 scopus 로고
    • Cell cycle characteristics of human solid tumors in vivo
    • Young, R. C., and DeVita, V. T. Cell cycle characteristics of human solid tumors in vivo. Cell Tissue Kinet., 3: 285-290, 1970.
    • (1970) Cell Tissue Kinet. , vol.3 , pp. 285-290
    • Young, R.C.1    DeVita, V.T.2
  • 25
    • 0036039795 scopus 로고    scopus 로고
    • Potentiation of tumor necrosis factor-α-induced cell death by rottlerin through a cytochrome-c-independent pathway
    • Basu, A., Johnson, D. E., and Woolard, M. D. Potentiation of tumor necrosis factor-α-induced cell death by rottlerin through a cytochrome-c-independent pathway. Exp. Cell Res., 278: 209-214, 2002.
    • (2002) Exp. Cell Res. , vol.278 , pp. 209-214
    • Basu, A.1    Johnson, D.E.2    Woolard, M.D.3
  • 26
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies, S. P., Reddy, H., Caivano, M., and Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J., 351: 95-105, 2000.
    • (2000) Biochem. J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 27
    • 0037189498 scopus 로고    scopus 로고
    • Infection of glioma cells with Sindbis virus induces selective activation and tyrosine phosphorylation of protein kinase C δ. Implications for Sindbis virus-induced apoptosis
    • Zrachia, A., Dobroslav, M., Blass, M., Kazimirsky, G., Kronfeld, I., Blumberg, P. M., Kobiler, D., Lustig, S., and Brodie, C. Infection of glioma cells with Sindbis virus induces selective activation and tyrosine phosphorylation of protein kinase C δ. Implications for Sindbis virus-induced apoptosis. J. Biol. Chem., 277: 23693-23701, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 23693-23701
    • Zrachia, A.1    Dobroslav, M.2    Blass, M.3    Kazimirsky, G.4    Kronfeld, I.5    Blumberg, P.M.6    Kobiler, D.7    Lustig, S.8    Brodie, C.9
  • 28
    • 0036132855 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of protein kinase Cδ is essential for its apoptotic effect in response to etoposide
    • Blass, M., Kronfeld, I., Kazimirsky, G., Blumberg, P. M., and Brodie, C. Tyrosine phosphorylation of protein kinase Cδ is essential for its apoptotic effect in response to etoposide. Mol. Cell. Biol., 22: 182-195, 2002.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 182-195
    • Blass, M.1    Kronfeld, I.2    Kazimirsky, G.3    Blumberg, P.M.4    Brodie, C.5
  • 29
    • 0034668779 scopus 로고    scopus 로고
    • Divergence in the anti-apoptotic signaling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC 12 cells: Rescue by bFGF involves protein kinase Cδ
    • Wert, M. M., and Palfrey, H. C. Divergence in the anti-apoptotic signaling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC 12 cells: rescue by bFGF involves protein kinase Cδ. Biochem. J., 352: 175-182, 2000.
    • (2000) Biochem. J. , vol.352 , pp. 175-182
    • Wert, M.M.1    Palfrey, H.C.2
  • 30
    • 0031684848 scopus 로고    scopus 로고
    • Protein kinase C-δ is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation
    • Li, W., Jiang, Y. X., Zhang, J., Soon, L., Flechner, L., Kapoor, V., Pierce, J. H., and Wang, L. H. Protein kinase C-δ is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation. Mol. Cell. Biol., 18: 5888-5898, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5888-5898
    • Li, W.1    Jiang, Y.X.2    Zhang, J.3    Soon, L.4    Flechner, L.5    Kapoor, V.6    Pierce, J.H.7    Wang, L.H.8
  • 31
    • 0027941342 scopus 로고
    • Stimulation of the platelet-derived growth factor β receptor signaling pathway activates protein kinase C-δ
    • Li, W., Yu, J. C., Michieli, P., Beeler, J. F., Ellmore, N., Heidaran, M. A., and Pierce, J. H. Stimulation of the platelet-derived growth factor β receptor signaling pathway activates protein kinase C-δ. Mol. Cell. Biol., 14: 6727-6735, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6727-6735
    • Li, W.1    Yu, J.C.2    Michieli, P.3    Beeler, J.F.4    Ellmore, N.5    Heidaran, M.A.6    Pierce, J.H.7
  • 32
    • 0033581954 scopus 로고    scopus 로고
    • Increased protein kinase C δ in mammary tumor cells: Relationship to transformation and metastatic progression
    • Kiley, S. C., Clark, K. J., Duddy, S. K., Welch, D. R., and Jaken, S. Increased protein kinase C δ in mammary tumor cells: relationship to transformation and metastatic progression. Oncogene, 18: 6748-6757, 1999.
    • (1999) Oncogene , vol.18 , pp. 6748-6757
    • Kiley, S.C.1    Clark, K.J.2    Duddy, S.K.3    Welch, D.R.4    Jaken, S.5
  • 33
    • 0033168515 scopus 로고    scopus 로고
    • Protein kinase C δ involvement in mammary tumor cell metastasis
    • Kiley, S. C., Clark, K. J., Goodnough, M., Welch, D. R., and Jaken, S. Protein kinase C δ involvement in mammary tumor cell metastasis. Cancer Res., 59: 3230-3238, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 3230-3238
    • Kiley, S.C.1    Clark, K.J.2    Goodnough, M.3    Welch, D.R.4    Jaken, S.5
  • 34
    • 85047683702 scopus 로고    scopus 로고
    • Protein kinase Cδ amplifies ceramide formation via mitochondrial signaling in prostate cancer cells
    • Sumitomo, M., Ohba, M., Asakuma, J., Asano, T., Kuroki, T., and Hayakawa, M. Protein kinase Cδ amplifies ceramide formation via mitochondrial signaling in prostate cancer cells. J. Clin. Investig., 109: 827-836, 2002.
    • (2002) J. Clin. Investig. , vol.109 , pp. 827-836
    • Sumitomo, M.1    Ohba, M.2    Asakuma, J.3    Asano, T.4    Kuroki, T.5    Hayakawa, M.6
  • 35
    • 0034698182 scopus 로고    scopus 로고
    • Mitochondrial translocation of protein kinase C δ in phorbol ester-induced cytochrome c release and apoptosis
    • Majumder, P. K., Pandey, P., Sun, X., Cheng, K., Datta, R., Saxena, S., Kharbanda, S., and Kufe, D. Mitochondrial translocation of protein kinase C δ in phorbol ester-induced cytochrome c release and apoptosis. J. Biol. Chem., 275: 21793-21796, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21793-21796
    • Majumder, P.K.1    Pandey, P.2    Sun, X.3    Cheng, K.4    Datta, R.5    Saxena, S.6    Kharbanda, S.7    Kufe, D.8
  • 36
    • 0036087033 scopus 로고    scopus 로고
    • Increased localization and substrate activation of protein kinase Cδ in lung epithelial cells following exposure to asbestos
    • Lounsbury, K. M., Stem, M., Taatjes, D., Jaken, S., and Mossman, B. T. Increased localization and substrate activation of protein kinase Cδ in lung epithelial cells following exposure to asbestos. Am. J. Pathol., 160: 1991-2000, 2002.
    • (2002) Am. J. Pathol. , vol.160 , pp. 1991-2000
    • Lounsbury, K.M.1    Stem, M.2    Taatjes, D.3    Jaken, S.4    Mossman, B.T.5


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