A deletion mutant of heregulin increases the sensitivity of breast cancer cells to chemotherapy without promoting tumorigenicity

Oncogene

Volumn 22, Issue 22, 2003, Pages 3441-3451

  Atlas, Ella ^a   Bojanowski, Kozystof ^a,b   Mehmi, Inderjit ^a   Lupu, Ruth ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Sunny BioDiscovery   (United States)

Author keywords

Antiestrogen resistance; Breast cancer; Doxorubicin; Drug resistance; Estrogen dependence; HRG; Mutants

Indexed keywords

DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; RECEPTOR PROTEIN; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; BREAST CANCER; CANCER INVASION; CARCINOGENICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DELETION MUTANT; DISSOCIATION; DNA DETERMINATION; DRUG BINDING; DRUG SENSITIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TUMOR PROMOTION;

BREAST NEOPLASMS; CULTURE MEDIA; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; NEUREGULIN-1; SEQUENCE DELETION; TRANSFECTION; TUMOR CELLS, CULTURED;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0038118346     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206410     Document Type: Article

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