Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs

BMC Evolutionary Biology

Volumn 4, Issue , 2004, Pages

  Brown, James R ^a   Koretke, Kristin K ^a   Birkeland, Marian L ^a   Sanseau, Philippe ^a   Patrick, Denis R ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANURA; CHORDATA; FUNGI; INVERTEBRATA; MAMMALIA; METAZOA; VERTEBRATA;

ANTINEOPLASTIC AGENT; AURKB PROTEIN, HUMAN; AURKC PROTEIN, HUMAN; AURORA B KINASE; AURORA C KINASE; AURORA KINASE; ENZYME INHIBITOR; PROTEIN SERINE THREONINE KINASE;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL MODEL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CHORDATA; CLASSIFICATION; ENZYME ACTIVE SITE; HUMAN; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHYLOGENY; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; AURORA KINASE B; AURORA KINASE C; AURORA KINASES; CATALYTIC DOMAIN; CHORDATA; ENZYME INHIBITORS; EVOLUTION, MOLECULAR; HUMANS; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT;

EID: 8744283817     PISSN: 14712148     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2148-4-39     Document Type: Article

References (49)

1. Carmena M, Earnshaw WC: The cellular geography of aurora kinases. Nat Rev Mol Cell Biol 2003, 4:842-854.
2. Nigg EA: Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol 2001, 2:21-32.
3. Glover DM, Leibowitz MH, McLean DA, Parry H: Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 1995, 81:95-105.
4. Reich A, Yanai A, Mesilaty-Gross S, Chen-Moses A, Wides R, Motro B: Cloning, mapping, and expression of ial, a novel Drosophila member of the Ipl1/aurora mitotic control kinase family. DNA Cell Biol 1999, 18:593-603.
5. Schumacher JM, Golden A, Donovan PJ: AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell Biol 1998, 143:1635-1646.
6. Schumacher JM, Ashcroft N, Donovan PJ, Golden A: A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Development 1998,125:4391-4402.
7. Francisco L, Wang W, Chan CS: Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation. Mol Cell Biol 1994, 14:4731-4740.
8. Petersen J, Paris J, Willer M, Philippe M, Hagan IM: The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation. J Cell Sci 2001, 114:4371-4384.
9. Roghi C, Giet R, Uzbekov R, Morin N, Chartrain I, Le Guellec R, Couturier A, Doree M, Philippe M, Prigent C: The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. J Cell Sci 1998, 111 (Pt 5):557-572.
10. Adams RR, Wheatley SP, Gouldsworthy AM, Kandels-Lewis SE, Carmena M, Smythe C, Gerloff DL, Earnshaw WC: INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol 2000, 10:1075-1078.
11. Bernard M, Sanseau P, Henry C, Couturier A, Prigent C: Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter. Genomics 1998, 53:406-409.
12. Kimura M, Matsuda Y, Yoshioka T, Okano Y: Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3. J Biol Chem 1999, 274:7334-7340.
13. Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ, Plowman GD: A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 1998, 17:3052-3065.
14. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S: Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998, 20:189-193.
15. Littlepage LE, Wu H, Andresson T, Deanehan JK, Amundadottir LT, Ruderman JV: Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A. Proc Natl Acad Sci U S A 2002, 99:15440-15445.
16. Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan J, Chan F, MacCarthy-Morrogh L, Ponder BA, Nagase H, Burn J, Ball S, Almeida M, Linardopoulos S, Balmain A: Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003, 34:403-412.
17. Ota T, Suto S, Katayama H, Han ZB, Suzuki F, Maeda M, Tanino M, Terada Y, Tatsuka M: Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability. Cancer Res 2002, 62:5168-5177.
18. Bicher A, Ault K, Kimmelman A, Gershenson D, Reed E, Liang B: Loss of heterozygosity in human ovarian cancer on chromosome 19q. Gynecol Oncol 1997, 66:36-40.
19. Hoglund M, Gorunova L, Andren-Sandberg A, Dawiskiba S, Mitelman F, Johansson B: Cytogenetic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinomas: frequent loss of 19p13.3 and gain of 19q13.1-13.2. Genes Chromosomes Cancer 1998, 21:8-16.
20. Mahadevan D, Bearss DJ, Vankayalapati H: Structure-based design of novel anti-cancer agents targeting aurora kinases. Curr Med Chem Anti -Canc Agents 2003, 3:25-34.
21. Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM: The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochoremicrotubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol 2003, 161:281-294.
22. Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS: Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 2003, 161:267-280.
23. Harrington EA, Bebbington D, Moore J, Rasmussen RK, Ajose-Adeogun AO, Nakayama T, Graham JA, Demur C, Hercend T, Diu-Hercend A, Su M, Golec JM, Miller KM: VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat Med 2004, 10:262-267.
24. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997,25:3389-3402.
25. Aparicio S, Chapman J, Stupka E, Putnam N, Chia JM, Dehal P, Christoffels A, Rash S, Hoon S, Smit A, Gelpke MD, Roach J, Oh T, Ho IY, Wong M, Detter C, Verhoef F, Predki P, Tay A, Lucas S, Richardson P, Smith SF, Clark MS, Edwards YJ, Doggett N, Zharkikh A, Tavtigian SV, Pruss D, Barnstead M, Evans C, Baden H, Powell J, Glusman G, Rowen L, Hood L, Tan YH, Elgar G, Hawkins T, Venkatesh B, Rokhsar D, Brenner S: Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science 2002, 297:1301-1310.
26. Centre The Sanger Sequencing: The Danio rerio Sequencing Project. 2004.
27. Dehal P, Satou Y, Campbell RK, Chapman J, Degnan B, De Tomaso A, Davidson B, Di Gregorio A, Gelpke M, Goodstein DM, Harafuji N, Hastings KE, Ho I, Hotta K, Huang W, Kawashima T, Lemaire P, Martinez D, Meinertzhagen IA, Necula S, Nonaka M, Putnam N, Rash S, Saiga H, Satake M, Terry A, Yamada L, Wang HG, Awazu S, Azumi K, Boore J, Branno M, Chin-Bow S, DeSantis R, Doyle S, Francino P, Keys DN, Haga S, Hayashi H, Hino K, Imai KS, Inaba K, Kano S, Kobayashi K, Kobayashi M, Lee BI, Makabe KW, Manohar C, Matassi G, Medina M, Mochizuki Y, Mount S, Morishita T, Miura S, Nakayama A, Nishizaka S, Nomoto H, Ohta F, Oishi K, Rigoutsos I, Sano M, Sasaki A, Sasakura Y, Shoguchi E, T Shin-i, Spagnuolo A, Stainier D, Suzuki MM, Tassy O, Takatori N, Tokuoka M, Yagi K, Yoshizaki F, Wada S, Zhang C, Hyatt PD, Larimer F, Detter C, Doggett N, Glavina T, Hawkins T, Richardson P, Lucas S, Kohara Y, Levine M, Satoh N, Rokhsar DS: The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science 2002, 298:2157-2167.
28. Adams Richard R., Carmena Mar, Earnshaw William C.: Chromosomal passengers and the (aurora) ABCs of mitosis. Trends in Cell Biology 2001, 11:49-54.
29. Cheetham GM, Knegtel RM, Coll JT, Renwick SB, Swenson L, Weber P, Lippke JA, Austen DA: Crystal structure of aurora-2, an oncogenic serine/threonine kinase. J Biol Chem 2002,277:42419-42422.
30. Castro A, Vigneron S, Bernis C, Labbe JC, Prigent C, Lorca T: The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A. EMBO Rep 2002, 3:1209-1214.
31. Arlot-Bonnemains Y, Klotzbucher A, Giet R, Uzbekov R, Bihan R, Prigent C: Identification of a functional destruction box in the Xenopus laevis aurora-A kinase pEg2. FEBS Lett 2001,508:149-152.
32. Siman-Tov MM, Ivens AC, Jaffe CL: Identification and cloning of Lmairk, a member of the Aurora/Ipl1p protein kinase family, from the human protozoan parasite Leishmania. Biochim Biophys Acta 2001, 1519:241-245.
33. Shannon KB, Salmon ED: Chromosome dynamics: new light on Aurora B kinase function. Curr Biol 2002, 12:R458-R460.
34. Murata-Hori M, Wang YL: The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis. Curr Biol 2002, 12:894-899.
35. Kallio MJ, McCleland ML, Stukenberg PT, Gorbsky GJ: Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol 2002, 12:900-905.
36. Frank-Vaillant M, Haccard O, Thibier C, Ozon R, Arlot-Bonnemains Y, Prigent C, Jessus C: Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes. J Cell Sci 2000, 113 (Pt 7):1127-1138.
37. Romano A, Guse A, Krascenicova I, Schnabel H, Schnabel R, Glotzer M: CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1. J Cell Biol 2003, 161:229-236.
38. Adams Jerry, Huang Pearl, Patrick Denis: A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis. Current Opinion in Chemical Biology 2002, 6:486-492.
39. Fischer OM, Streit S, Hart S, Ullrich A: Beyond Herceptin and Gleevec. Curr Opin Chem Biol 2003, 7:490-495.
40. Capdeville R, Buchdunger E, Zimmermann J, Matter A: Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug. Nat Rev Drug Discov 2002, 1:493-502.
41. Thompson JD, Higgins DG, Gibson TJ: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994, 22:4673-4680.
42. Felsentein J: PHYLIP (Phylogenetic Inference Package). Seattle, Department of Genetics, University of Washington; 2000.
43. Strimmer K, von Haesler A: Quartet puzzling: a quartet maximum likelihood method for reconstructing tree topologies. Mol Biol Evol 1996, 13:964-969.
44. Swofford DL: PAUP*. Phylogenetic Analysis Using Parsimony (*and Other Methods). Sunderland, Massachusetts, Sinauer Associates; 1999.
45. Huelsenbeck JP, Ronquist F: MRBAYES: Bayesian inference of phylogenetic trees. Bioinformatics 2001, 17:754-755.
46. Ronquist F, Huelsenbeck JP: MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 2003,19:1572-1574.
47. Page RD: TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 1996,12:357-358.
48. Guex N, Peitsch MC: SWISS-MODEL and the Swiss-Pdb-Viewer: an environment for comparative protein modeling. Electrophoresis 1997, 18:2714-2723.
49. Liang J, Edelsbrunner H, Woodward C: Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design. Protein Sci 1998, 7:1884-1897.