Toxicological comparison of cigarette smoke and e-cigarette aerosol using a 3D in vitro human respiratory model

Regulatory Toxicology and Pharmacology

Volumn 103, Issue , 2019, Pages 314-324

  Czekala, Lukasz ^a   Simms, Liam ^a   Stevenson, Matthew ^a   Tschierske, Nicole ^a   Maione, Anna G ^b   Walele, Tanvir ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b MATTEK CORPORATION   (United States)

Author keywords

Aerosol; Air liquid interface; Cigarette; E cigarette; Inflammation; Organotypic tissue model; Oxidative stress; Smoke; Toxicity

Indexed keywords

HISTONE H2AX; INTERLEUKIN 6; INTERLEUKIN 8; NICOTINE; CYTOKINE;

ADULT; AEROSOL; AIR QUALITY CONTROL; ARTICLE; BIOLOGICAL ACTIVITY; BLUEBERRY; CIGARETTE SMOKING; COMPARATIVE TOXICOLOGY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; HEALTH HAZARD; HEALTH IMPACT ASSESSMENT; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG MODEL; LUNG PARENCHYMA; LUNG TOXICITY; MALE; MANUAL SMOKING MACHINE; NONBIOLOGICAL MODEL; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY EPITHELIAL MODEL; THREE DIMENSIONAL IMAGING; TOXICITY TESTING; VAPING; YOUNG ADULT; COMPARATIVE STUDY; DRUG EFFECT; ELECTRONIC CIGARETTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PATHOLOGY; RESPIRATORY MUCOSA; TANDEM MASS SPECTROMETRY;

AEROSOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIGARETTE SMOKING; CYTOKINES; ELECTRONIC NICOTINE DELIVERY SYSTEMS; HUMANS; MALE; NICOTINE; OXIDATIVE STRESS; RESPIRATORY MUCOSA; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 85062152686     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2019.01.036     Document Type: Article

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