Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches

Regulatory Toxicology and Pharmacology

Volumn 93, Issue , 2018, Pages 62-70

  Taylor, Mark ^a   Thorne, David ^a   Carr, Tony ^a   Breheny, Damien ^a   Walker, Paul ^b   Proctor, Christopher ^a   Gaça, Marianna ^a  

^a BRITISH AMERICAN TOBACCO   (United Kingdom)

^b CYPROTEX DISCOVERY LTD   (United Kingdom)

Author keywords

Cigarette smoke; High content screening; In vitro; Lung epithelial; Reporter assay; Tobacco heating products

Indexed keywords

CIGARETTE SMOKE; HISTONE H2AX; STRESS ACTIVATED PROTEIN KINASE; TOBACCO HEATING PRODUCT; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HBEC CELL LINE (BRONCHIAL); HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NCI-H292 CELL LINE; OXIDATIVE STRESS; PARTICULATE MATTER; PRIORITY JOURNAL; SCREENING; TOXICITY TESTING; TRANSCRIPTION INITIATION; AEROSOL; ANALYSIS; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; ELECTRONIC CIGARETTE; HEATING; PHARMACOLOGY; PHYSIOLOGY; PROCEDURES; RESPIRATORY MUCOSA; TOBACCO;

AEROSOLS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRONIC NICOTINE DELIVERY SYSTEMS; HEATING; HUMANS; PARTICULATE MATTER; RESPIRATORY MUCOSA; TOBACCO PRODUCTS;

EID: 85033475140     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2017.08.016     Document Type: Article

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