Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines

Oral Oncology

Volumn 52, Issue , 2016, Pages 58-65

  Yu, Vicky ^a   Rahimy, Mehran ^a   Korrapati, Avinaash ^a   Xuan, Yinan ^a   Zou, Angela E ^a   Krishnan, Aswini R ^a   Tsui, Tzuhan ^a   Aguilera, Joseph A ^b   Advani, Sunil ^b   Crotty Alexander, Laura E ^a,c   Brumund, Kevin T ^a   Wang Rodriguez, Jessica ^c   Ongkeko, Weg M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

DNA damage; Electronic cigarettes; Head and neck squamous cell carcinoma (HNSCC); Nicotine; Oral cancer; Smoking; Strand breaks

Indexed keywords

DOUBLE STRANDED DNA; HISTONE H2AX; NICOTINE; NICOTINIC AGENT;

APOPTOSIS; ARTICLE; CANCER CELL LINE; CARCINOGENESIS; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CLONOGENIC ASSAY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; DNA STRAND BREAKAGE; ELECTRONIC CIGARETTE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; GENOTOXICITY; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; VAPOR; ADVERSE EFFECTS; DNA DAMAGE; DRUG EFFECTS; EPITHELIUM CELL; HEAD AND NECK TUMOR; METABOLISM; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; VOLATILIZATION;

CARCINOMA, SQUAMOUS CELL; CELL DEATH; CELL LINE, TUMOR; DNA DAMAGE; ELECTRONIC CIGARETTES; EPITHELIAL CELLS; HEAD AND NECK NEOPLASMS; HUMANS; NICOTINE; NICOTINIC AGONISTS; VOLATILIZATION;

EID: 84962388369     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2015.10.018     Document Type: Article

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