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Volumn 26, Issue 6, 2016, Pages 477-491

Electronic cigarette aerosol induces significantly less cytotoxicity than Tobacco smoke

Author keywords

Air liquid interface; e cigarettes; Lung epithelial cells; Tobacco smoke

Indexed keywords

CIGARETTE SMOKE; NICOTINE; TOBACCO SMOKE; AEROSOL; SMOKE;

EID: 85006784479     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376516.2016.1217112     Document Type: Article
Times cited : (86)

References (99)
  • 1
    • 80052031025 scopus 로고    scopus 로고
    • Assessment of an in vitro whole cigarette smokxposure system: The Borgwaldt RM20S 8-syringe smoking machine
    • Adamson J, Azzopardi D, Errington G, et al. Assessment of an in vitro whole cigarette smokxposure system: the Borgwaldt RM20S 8-syringe smoking machine. Chem Cent J. 2011;5:50-60.
    • (2011) Chem Cent J , vol.5 , pp. 50-60
    • Adamson, J.1    Azzopardi, D.2    Errington, G.3
  • 2
    • 84865849111 scopus 로고    scopus 로고
    • Real-time assessment of cigarette smoke particleposition in vitro
    • Adamson J, Hughes S, Azzopardi D, et al. Real-time assessment of cigarette smoke particleposition in vitro. Chem Cent J. 2012;6:98.
    • (2012) Chem Cent J , vol.6 , pp. 98
    • Adamson, J.1    Hughes, S.2    Azzopardi, D.3
  • 3
    • 84904759468 scopus 로고    scopus 로고
    • An inter-machine comparison of tobacco smoke particleposition in vitro from six independent smokxposure systems
    • Adamson J, Thorne D, Errington G, et al. An inter-machine comparison of tobacco smoke particleposition in vitro from six independent smokxposure systems. Toxicol In Vitro. 2014;28:1320-8.
    • (2014) Toxicol in Vitro , vol.28 , pp. 1320-1328
    • Adamson, J.1    Thorne, D.2    Errington, G.3
  • 4
    • 84874589929 scopus 로고    scopus 로고
    • Quantification of cigarette smoke particleposition in vitro using a triplicate quartz crystal microbalancxposure chamber
    • Adamson J, Thorne D, McAughey J, et al. Quantification of cigarette smoke particleposition in vitro using a triplicate quartz crystal microbalancxposure chamber. Biomed Res Int. 2013;2013:685074.
    • (2013) Biomed Res Int , vol.2013
    • Adamson, J.1    Thorne, D.2    McAughey, J.3
  • 5
    • 21244460472 scopus 로고    scopus 로고
    • Thffect of inhalation volume and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking
    • Armitage AK, Dixon M, Frost BE, et al. Thffect of inhalation volume and breath-hold duration on the retention of nicotine and solanesol in the human respiratory tract and on subsequent plasma nicotine concentrations during cigarette smoking. Beitr Tabakforsch Int. 2004;4:240-9.
    • (2004) Beitr Tabakforsch Int , vol.4 , pp. 240-249
    • Armitage, A.K.1    Dixon, M.2    Frost, B.E.3
  • 6
    • 84937019857 scopus 로고    scopus 로고
    • Evaluation of an air-liquid interface cell culture model for studies on the inflammatory and cytotoxic responses to tobacco smoke aerosols
    • Azzopardi D, Haswell LE, Foss-Smith G, et al. Evaluation of an air-liquid interface cell culture model for studies on the inflammatory and cytotoxic responses to tobacco smoke aerosols. Toxicol In Vitro. 2015;29:1720-8.
    • (2015) Toxicol in Vitro , vol.29 , pp. 1720-1728
    • Azzopardi, D.1    Haswell, L.E.2    Foss-Smith, G.3
  • 7
    • 21244466435 scopus 로고    scopus 로고
    • A review of the incidence and consequences of cigarette filter venlocking among smokers
    • Baker RR, Lewis LS. A review of the incidence and consequences of cigarette filter venlocking among smokers. Beitr Tabakforsch Int. 2001;4:209-28.
    • (2001) Beitr Tabakforsch Int , vol.4 , pp. 209-228
    • Baker, R.R.1    Lewis, L.S.2
  • 8
    • 84889561299 scopus 로고    scopus 로고
    • Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids
    • Behar RZ, Davis B, Wang Y, et al. Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids. Toxicol In Vitro. 2014;28:198-208.
    • (2014) Toxicol in Vitro , vol.28 , pp. 198-208
    • Behar, R.Z.1    Davis, B.2    Wang, Y.3
  • 9
    • 84922647841 scopus 로고    scopus 로고
    • Puffing topography and nicotine intake olectronic cigarettsers
    • Behar RZ, Hu Talbo. Puffing topography and nicotine intake olectronic cigarettsers. PLoS One. 2015;10:e0117222.
    • (2015) Plos One , vol.10
    • Behar, R.Z.1    Talbo, H.2
  • 10
    • 4344594118 scopus 로고    scopus 로고
    • A review of the influence of particle size, puff volume, and inhalation pattern on theposition of cigarette smoke particles in the respiratory tract
    • Bernstein DM. A review of the influence of particle size, puff volume, and inhalation pattern on theposition of cigarette smoke particles in the respiratory tract. Inhal Toxicol. 2004;16:675-89.
    • (2004) Inhal Toxicol , vol.16 , pp. 675-689
    • Bernstein, D.M.1
  • 11
    • 26844559073 scopus 로고    scopus 로고
    • Evaluation of the genotoxic and cytotoxic potential of mainstream whole smoke and smoke condensate from a cigarette containing a novel carbon filter
    • Bombick DW, Bombick BR, Ayres PH, et al. Evaluation of the genotoxic and cytotoxic potential of mainstream whole smoke and smoke condensate from a cigarette containing a novel carbon filter. Fundam Appl Toxicol. 1997;39:11-7.
    • (1997) Fundam Appl Toxicol , vol.39 , pp. 11-17
    • Bombick, D.W.1    Bombick, B.R.2    Ayres, P.H.3
  • 12
    • 84907969236 scopus 로고    scopus 로고
    • Application of a modified gaseous exposure system to the in vitro toxicological assessment of tobacco smoke toxicants
    • Breheny D, Cunningham F, Kilford J, et al. Application of a modified gaseous exposure system to the in vitro toxicological assessment of tobacco smoke toxicants. Environ Moutagen. 2014;55:662-72.
    • (2014) Environ Moutagen , vol.55 , pp. 662-672
    • Breheny, D.1    Cunningham, F.2    Kilford, J.3
  • 13
    • 85046843454 scopus 로고    scopus 로고
    • Borgwaldt, Smoking Machine RM20S. Available from: http://borgwaldt.hauni.com/en/instruments/smoking-machines/rotary/smoking-machine-rm20s.html[last accessed 1 June 2016].
  • 14
    • 0017644155 scopus 로고
    • Assessment of carcinogenic volatile n-nitrosamines in tobacco and in mainstream and sidestream smoke from cigarettes
    • Brunnemann KD, Yu L, Hoffmann D. Assessment of carcinogenic volatile n-nitrosamines in tobacco and in mainstream and sidestream smoke from cigarettes. Cancer Res. 1977;37:3218-22.
    • (1977) Cancer Res , vol.37 , pp. 3218-3222
    • Brunnemann, K.D.1    Yu, L.2    Hoffmann, D.3
  • 15
    • 77952955291 scopus 로고    scopus 로고
    • Effect of an electronic nicotinelivery device (E cigarette) on desire to smoke and withdrawal, user preferences and nicotinelivery: Randomised cross-over trial
    • Bullen C, McRobbie H, Thornley S, et al. Effect of an electronic nicotinelivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotinelivery: randomised cross-over trial. Tob Control. 2010;19:98-103.
    • (2010) Tob Control , vol.19 , pp. 98-103
    • Bullen, C.1    McRobbie, H.2    Thornley, S.3
  • 16
    • 42149192001 scopus 로고    scopus 로고
    • Mandated lowering of toxicants in cigarette smoke: Escription of the World Health Organization TobReg proposal
    • Burns DM, Dybing E, Gray N, et al. Mandated lowering of toxicants in cigarette smoke: escription of the World Health Organization TobReg proposal. Tob Control. 2008;17:132-41.
    • (2008) Tob Control , vol.17 , pp. 132-141
    • Burns, D.M.1    Dybing, E.2    Gray, N.3
  • 17
    • 84867128509 scopus 로고    scopus 로고
    • A systematic review of nicotiny inhalation: Is there a role for the inhaled route?
    • Caldwell B, Sumner W, Crane J. A systematic review of nicotiny inhalation: is there a role for the inhaled route? Nicotine Tob Res. 2012;14:1127-39.
    • (2012) Nicotine Tob Res , vol.14 , pp. 1127-1139
    • Caldwell, B.1    Sumner, W.2    Crane, J.3
  • 18
    • 84899640614 scopus 로고    scopus 로고
    • Electronic cigarettes: Human health effects
    • Callahan-Lyon P. Electronic cigarettes: human health effects. Tob Control. 2014;23:236-40.
    • (2014) Tob Control , vol.23 , pp. 236-240
    • Callahan-Lyon, P.1
  • 19
    • 84872840542 scopus 로고    scopus 로고
    • FDA summary of adversvents on electronic cigarettes
    • Chen IL. FDA summary of adversvents on electronic cigarettes. Nicotine Tob Res. 2013;15:615-6.
    • (2013) Nicotine Tob Res , vol.15 , pp. 615-616
    • Chen, I.L.1
  • 20
    • 85046873403 scopus 로고    scopus 로고
    • Chemicavaluation olectronic cigarettes
    • Cheng T. Chemicavaluation olectronic cigarettes. Tob Control. 2014;23:211-17.
    • (2014) Tob Control , vol.23 , pp. 211-217
    • Cheng, T.1
  • 21
    • 84899692877 scopus 로고    scopus 로고
    • Relationship between cigarette yields and smoking timndeifferent machine smoking regimes
    • Colard S, Verron T, Julien R, et al. Relationship between cigarette yields and smoking timndeifferent machine smoking regimes. Beitr Tabakforsch Int. 2014;26:4-18.
    • (2014) Beitr Tabakforsch Int , vol.26 , pp. 4-18
    • Colard, S.1    Verron, T.2    Julien, R.3
  • 22
    • 85046859566 scopus 로고    scopus 로고
    • CORESTA 2015oo https://www.coresta.org/sites/default/files/technical_documents/main/CRM_81.pdf
    • (2015)
  • 23
    • 84859931052 scopus 로고    scopus 로고
    • Estimation of nicotine and tar yields from human-smoked cigarettes before and after the implementation of the cigarette ignition propensity regulations in Canada
    • Côté F, Létourneau C, Mullard G, Voisine R. Estimation of nicotine and tar yields from human-smoked cigarettes before and after the implementation of the cigarette ignition propensity regulations in Canada. Reg Tox Pharm. 2011;61:S51-S9.
    • (2011) Reg Tox Pharm , vol.61 , pp. S51-S59
    • Côté, F.1    Létourneau, C.2    Mullard, G.3    Voisine, R.4
  • 24
    • 84961972646 scopus 로고    scopus 로고
    • Real-time characterization o-cigarettes use: The 1 million puffs study
    • Dautzenberg B, Bricard D. Real-time characterization o-cigarettes use: the 1 million puffs study. J Addict Res Ther. 2015;6:2.
    • (2015) J Addict Res Ther , vol.6 , pp. 2
    • Dautzenberg, B.1    Bricard, D.2
  • 25
    • 84871552259 scopus 로고    scopus 로고
    • Determination of nicotine absorption from multiple tobacco products and nicotine gum
    • Digard H, Proctor C, Kulasekaran A, et al. Determination of nicotine absorption from multiple tobacco products and nicotine gum. Nicotine Tob Res. 2013;15:255-61.
    • (2013) Nicotine Tob Res , vol.15 , pp. 255-261
    • Digard, H.1    Proctor, C.2    Kulasekaran, A.3
  • 26
    • 84923275858 scopus 로고    scopus 로고
    • Variation in tobacco and mainstream smoke toxicant yields from selected commercial cigarette products
    • Eldridge A, Betson TR, Vinicius Gam, McAdam K. Variation in tobacco and mainstream smoke toxicant yields from selected commercial cigarette products. Regul Toxicoharmacol. 2015;71:409-27.
    • (2015) Regul Toxicoharmacol , vol.71 , pp. 409-427
    • Eldridge, A.1    Betson, T.R.2    Gam, V.3    McAdam, K.4
  • 27
    • 85046879259 scopus 로고    scopus 로고
    • European Commission. 2015. 2015. http://ec.europa.eu/public_opinion/archives/ebs/ebs_429_en.pdf
    • (2015)
  • 28
    • 85046878982 scopus 로고    scopus 로고
    • European Commission. 2014. http://ec.europa.eu/health/tobacco/docs/dir_201440_en.pdf
    • (2014)
  • 29
    • 0042733260 scopus 로고    scopus 로고
    • Should the European Union lift than on snus? Evidence from the Swedish experience
    • Fagerström KO, Schildt EB. Should the European Union lift than on snus? Evidence from the Swedish experience. Addiction. 2003;98:1191-5.
    • (2003) Addiction , vol.98 , pp. 1191-1195
    • Fagerström, K.O.1    Schildt, E.B.2
  • 30
    • 84879402743 scopus 로고    scopus 로고
    • Evaluation olectronic cigarettse (Vaping) topography and estimation of liquid consumption: Implications for research protocol standards definition and for public health authorities’ regulation
    • Farsalinos KE, Romagna G, Tsiapras D, et al. Evaluation olectronic cigarettse (vaping) topography and estimation of liquid consumption: implications for research protocol standards definition and for public health authorities’ regulation. Int J Environ Res Public Health. 2013;10:2500-14.
    • (2013) Int J Environ Res Public Health , vol.10 , pp. 2500-2514
    • Farsalinos, K.E.1    Romagna, G.2    Tsiapras, D.3
  • 31
    • 84898928389 scopus 로고    scopus 로고
    • Nicotine absorption from electronic cigarettse: Comparison between first and new-generation devices
    • Farsalinos KE, Spyrou A, Tsimopoulou K, et al. Nicotine absorption from electronic cigarettse: comparison between first and new-generation devices. Sci Rep. 2014;4:4133.
    • (2014) Sci Rep , vol.4 , pp. 4133
    • Farsalinos, K.E.1    Spyrou, A.2    Tsimopoulou, K.3
  • 32
    • 84936955095 scopus 로고    scopus 로고
    • E-cigarettes generate high levels of aldehydes only in ’dry puff’ conditions
    • Farsalinos KE, Voudris V, Poulas K. E-cigarettes generate high levels of aldehydes only in ’dry puff’ conditions. Addiction. 2015;110:1352-6.
    • (2015) Addiction , vol.110 , pp. 1352-1356
    • Farsalinos, K.E.1    Voudris, V.2    Poulas, K.3
  • 33
    • 0022400850 scopus 로고
    • Rat lung macrophage tumor cytotoxin production: Impairmeny chronic in vivo cigarette smokxposure
    • Flick DA, Gonzalez-Rothi RJ, Ocie Harris J, Gifford GE. Rat lung macrophage tumor cytotoxin production: impairmeny chronic in vivo cigarette smokxposure. Cancer Res. 1985;45:5225-9.
    • (1985) Cancer Res , vol.45 , pp. 5225-5229
    • Flick, D.A.1    Gonzalez-Rothi, R.J.2    Ocie Harris, J.3    Gifford, G.E.4
  • 34
    • 85046875572 scopus 로고    scopus 로고
    • Food and Drug Administration (FDA) 2012. http://www.fda.gov/downloads/TobaccoProducts/Labeling/RulesRegulationsGuidance/UCM297981.pdf
    • (2012)
  • 35
    • 85046849342 scopus 로고    scopus 로고
    • Food and Drug Administration (FDA) 2013. http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/ucm348930.pdf
    • (2013)
  • 36
    • 85046839294 scopus 로고    scopus 로고
    • Food and Drug Administration (FDA) 2016. https://www.gpo.gov/fdsys/pkg/FR-2016-05-10/pdf/2016-10685.pdf
    • (2016)
  • 37
    • 84928683914 scopus 로고    scopus 로고
    • An experimental method to study emissions from heated tobacco between 100-200 °C
    • Forste, Liu C, Duk G, et al. An experimental method to study emissions from heated tobacco between 100-200 °C. Chem Cent J. 2015;9:20.
    • (2015) Chem Cent J , vol.9 , pp. 20
    • Forste, L.C.1    Duk, G.2
  • 38
    • 84926088290 scopus 로고    scopus 로고
    • Characterisation of an aerosoxposure system to evaluate the genotoxicity of whole mainstream cigarette smoksing the in vitro γH2AX assay by high content screening
    • Garcia-Canton C, Errington G, Anadon A, Meredith C. Characterisation of an aerosoxposure system to evaluate the genotoxicity of whole mainstream cigarette smoksing the in vitro γH2AX assay by high content screening. BMharmacol Toxicol. 2014;15:41.
    • (2014) Bmharmacol Toxicol , vol.15 , pp. 41
    • Garcia-Canton, C.1    Errington, G.2    Anadon, A.3    Meredith, C.4
  • 39
    • 77952705525 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity in human lung epithelial A549 cells caused by airborne volatile organic compounds emitted from pine wood and oriented strand boards
    • Gminski R, Tang T, Mersch-Sundermann V. Cytotoxicity and genotoxicity in human lung epithelial A549 cells caused by airborne volatile organic compounds emitted from pine wood and oriented strand boards. Toxicol Lett. 2010;196:33-41.
    • (2010) Toxicol Lett , vol.196 , pp. 33-41
    • Gminski, R.1    Tang, T.2    Mersch-Sundermann, V.3
  • 40
    • 84893908308 scopus 로고    scopus 로고
    • Levels of selected carcinogens and toxicants in vapour from electronic cigarettes
    • Goniewicz ML, Knysak J, Gawron M, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014;23:133-9.
    • (2014) Tob Control , vol.23 , pp. 133-139
    • Goniewicz, M.L.1    Knysak, J.2    Gawron, M.3
  • 41
    • 84874942955 scopus 로고    scopus 로고
    • Patterns olectronic cigarettse and useeliefs about their safety and benefits: An internet survey
    • Goniewicz ML, Lingas EO, Hajek P. Patterns olectronic cigarettse and useeliefs about their safety and benefits: an internet survey. Drug Alcohol Rev. 2013;32:133-40.
    • (2013) Drug Alcohol Rev , vol.32 , pp. 133-140
    • Goniewicz, M.L.1    Lingas, E.O.2    Hajek, P.3
  • 42
    • 84922430794 scopus 로고    scopus 로고
    • Nicotine intake from electronic cigarettes on initiase and after 4 weeks of regulase
    • Hajek P, Goniewicz ML, Phillips A, et al. Nicotine intake from electronic cigarettes on initiase and after 4 weeks of regulase. Nicotine Tob Res. 2015;17:175-9.
    • (2015) Nicotine Tob Res , vol.17 , pp. 175-179
    • Hajek, P.1    Goniewicz, M.L.2    Phillips, A.3
  • 43
    • 85046874106 scopus 로고    scopus 로고
    • Health Canada. 1999. http://www.qp.gov.bc.ca/stat_reg/regs/health/oic_94.pdf
    • (1999)
  • 45
    • 84949117606 scopus 로고    scopus 로고
    • E-cigarettes: Online survey of UK smoking cessation practitioners
    • Hiscock R, Goniewicz ML, McEwen A, et al. E-cigarettes: online survey of UK smoking cessation practitioners. Tob Induc Dis. 2014;12:13.
    • (2014) Tob Induc Dis , vol.12 , pp. 13
    • Hiscock, R.1    Goniewicz, M.L.2    McEwen, A.3
  • 46
    • 0014043320 scopus 로고
    • The reduction of the tumorigenicity of cigarette smoke condensaty addition of sodium nitrate to tobacco
    • Hoffmann D, Wynder EL. The reduction of the tumorigenicity of cigarette smoke condensaty addition of sodium nitrate to tobacco. Cancer Res. 1967;27:172-4.
    • (1967) Cancer Res , vol.27 , pp. 172-174
    • Hoffmann, D.1    Wynder, E.L.2
  • 47
    • 0003192699 scopus 로고
    • ICRP publication 66: Human respiratory tract model for radiological protection; Elsevier health sciences
    • International Commission on Radiologicarotection (ICPR). ICRP publication 66: human respiratory tract model for radiological protection; Elsevier health sciences. Ann ICRP. 1994;24:1-3.
    • (1994) Ann ICRP , vol.24 , pp. 1-3
  • 48
    • 84957055763 scopus 로고    scopus 로고
    • Analysis of cigarette smokeposition within an in vitro exposure system for simulating exposure in the human respiratory tract
    • Ishikawa S, Suzuki T, Nagata Y. Analysis of cigarette smokeposition within an in vitro exposure system for simulating exposure in the human respiratory tract. Beitr Tabakforsch Int. 2016;27:20-9.
    • (2016) Beitr Tabakforsch Int , vol.27 , pp. 20-29
    • Ishikawa, S.1    Suzuki, T.2    Nagata, Y.3
  • 49
    • 84886571799 scopus 로고    scopus 로고
    • Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smokxposure in nasal and bronchial tissues
    • Iskandar AR, Martin F, Talikk, et al. Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smokxposure in nasal and bronchial tissues. BioMed Res Int. 2013;2013:512086.
    • (2013) Biomed Res Int , vol.2013
    • Iskandar, A.R.1    Martin, Talikk, F.2
  • 50
    • 85046863212 scopus 로고    scopus 로고
    • ISO. 1999. http://www.iso.org/iso/catalogue_detail.htm?csnumber=28324
    • (1999)
  • 51
    • 85046868582 scopus 로고    scopus 로고
    • ISO. 2000. http://www.iso.org/iso/iso_catalogue/catalogue_tc/catalogue_detail.htm?csnumber=28323
    • (2000)
  • 52
    • 85046866386 scopus 로고    scopus 로고
    • ISO. 2012. http://www.iso.org/iso/iso_catalogue/catalogue_tc/catalogue_detail.htm?csnumber=60404
    • (2012)
  • 53
    • 85024472801 scopus 로고    scopus 로고
    • Mouth levexposure and similarity to machine-smoked constituent yields
    • Jackson KJ, Schroede J, Hoffman AC. Mouth levexposure and similarity to machine-smoked constituent yields. Tob Regul Sci. 2016;2:3-8.
    • (2016) Tob Regul Sci , vol.2 , pp. 3-8
    • Jackson, K.J.1    Schroede, J.2    Hoffman, A.C.3
  • 54
    • 84859991085 scopus 로고    scopus 로고
    • A LC-MS/MS method for concurrenetermination of nicotine metabolites and role of CYP2A6 in nicotine metabolism in U937 macrophages: Implications in oxidative stress in HIV + smokers
    • Jin M, Earla R, Shah A, et al. A LC-MS/MS method for concurrenetermination of nicotine metabolites and role of CYP2A6 in nicotine metabolism in U937 macrophages: implications in oxidative stress in HIV + smokers. J Neuroimmunharmacol. 2012;7:289-99.
    • (2012) J Neuroimmunharmacol , vol.7 , pp. 289-299
    • Jin, M.1    Earla, R.2    Shah, A.3
  • 55
    • 78649963312 scopus 로고    scopus 로고
    • Evaluation of precision and accuracy of the Borgwaldt RM20S(®)smoking machinesigned for in vitro exposure
    • Kaur N, Lacass, Roya J-P, et al. Evaluation of precision and accuracy of the Borgwaldt RM20S(®)smoking machinesigned for in vitro exposure. Inhal Toxicol. 2010;22:1174-83.
    • (2010) Inhal Toxicol , vol.22 , pp. 1174-1183
    • Kaur, N.1    Lacass, Roya, J.-P.2
  • 56
    • 84866930428 scopus 로고    scopus 로고
    • Nicotine replacement therapy and harm reduction
    • Medicines and Healthcare products Regulatory Agency (MHRA). Nicotine replacement therapy and harm reduction. Drug Safety Update. 2010;3:6. https://www.gov.uk/drug-safety-update/nicotine-replacement-therapy-and-harm-reduction
    • (2010) Drug Safety Update , vol.3 , pp. 6
  • 57
    • 84978160558 scopus 로고    scopus 로고
    • Characterization of the Vitrocell® 24/48 in vitro aerosoxposure system using mainstream cigarette smoke
    • Majeed S, Frentzel S, Wagner S, et al. Characterization of the Vitrocell® 24/48 in vitro aerosoxposure system using mainstream cigarette smoke. Chem Cent J. 2014;8:62.
    • (2014) Chem Cent J , vol.8 , pp. 62
    • Majeed, S.1    Frentzel, S.2    Wagner, S.3
  • 58
    • 84925356752 scopus 로고    scopus 로고
    • Particloses in the pulmonary lobes olectronic and conventional cigarettsers
    • Manigrasso M, Buonanno G, Stabile L, et al. Particloses in the pulmonary lobes olectronic and conventional cigarettsers. Environ Pollut. 2015;202:24-31.
    • (2015) Environ Pollut , vol.202 , pp. 24-31
    • Manigrasso, M.1    Buonanno, G.2    Stabile, L.3
  • 59
    • 84991666710 scopus 로고    scopus 로고
    • Chemical composition of an e-cigarette aerosol? A quantitative comparison with cigarette smoke
    • Margham J, McAdam K, Forste, et al. Chemical composition of an e-cigarette aerosol? a quantitative comparison with cigarette smoke. Chem Res Toxicol. 2016 doi: 10.1021/acs.chemrestox.6b00188.
    • (2016) Chem Res Toxicol
    • Margham, J.1    McAdam, Forste, K.2
  • 60
    • 84857273961 scopus 로고    scopus 로고
    • Mouth level smokxposursing analysis of filters from smoked cigarettes: A study oight countries
    • Mariner DC, Ashley M, Shepperd CJ, et al. Mouth level smokxposursing analysis of filters from smoked cigarettes: a study oight countries. Regul Toxicoharmacol. 2011;61:S39-S50.
    • (2011) Regul Toxicoharmacol , vol.61 , pp. S39-S50
    • Mariner, D.C.1    Ashley, M.2    Shepperd, C.J.3
  • 61
    • 84908328821 scopus 로고    scopus 로고
    • Comparative in vitro toxicity profile olectronic and tobacco cigarettes, smokeless tobacco and nicotine replacement therapy products: E-liquids, extracts and collected aerosols
    • Misr, Leverette RD, Cooper BT, et al. Comparative in vitro toxicity profile olectronic and tobacco cigarettes, smokeless tobacco and nicotine replacement therapy products: e-liquids, extracts and collected aerosols. Int J Environ Res Public Health. 2014;11:11325-47.
    • (2014) Int J Environ Res Public Health , vol.11 , pp. 11325-11347
    • Misr, Leverette, R.D.1    Cooper, B.T.2
  • 62
    • 84939775011 scopus 로고    scopus 로고
    • Development of an in vitro cytotoxicity model for aerosoxposursing 3D reconstructed human airway tissue; application for assessment o-cigarette aerosol
    • Neilson L, Mankus C, Thorne D, et al. Development of an in vitro cytotoxicity model for aerosoxposursing 3D reconstructed human airway tissue; application for assessment o-cigarette aerosol. Toxicol In Vitro. 2015;29:1952-62.
    • (2015) Toxicol in Vitro , vol.29 , pp. 1952-1962
    • Neilson, L.1    Mankus, C.2    Thorne, D.3
  • 63
    • 84897360903 scopus 로고    scopus 로고
    • Estimating the harms of nicotine-containing products using thCDA approach
    • Nutt DJ, Phillips LD, Balfour D, et al. Estimating the harms of nicotine-containing products using thCDA approach. Eur Addict Res. 2014;20:218-25.
    • (2014) Eur Addict Res , vol.20 , pp. 218-225
    • Nutt, D.J.1    Phillips, L.D.2    Balfour, D.3
  • 64
    • 80052586257 scopus 로고    scopus 로고
    • Pharmacokinetic study of nicotine and its metabolite cotinine to clarify possible association between smoking and voiding dysfunction in rats using UPLC/ESI-MS
    • Onoue S, Yamamoto N, Seto Y, Yamada S. Pharmacokinetic study of nicotine and its metabolite cotinine to clarify possible association between smoking and voiding dysfunction in rats using UPLC/ESI-MS. Drug Metab Pharmacokinet. 2011;26:416-22.
    • (2011) Drug Metab Pharmacokinet , vol.26 , pp. 416-422
    • Onoue, S.1    Yamamoto, N.2    Seto, Y.3    Yamada, S.4
  • 65
    • 84963854291 scopus 로고    scopus 로고
    • Awareness and currense olectronic cigarettes in Indonesia, Malaysia, Qatar, and Greece: findings from 2011-2013 global adult tobacco surveys
    • GATS Collaborative Group. et al
    • Palipudi KM, Mbulo L, GATS Collaborative Group. et al. Awareness and currense olectronic cigarettes in Indonesia, Malaysia, Qatar, and Greece: findings from 2011-2013 global adult tobacco surveys. Nicotine Tob Res. 2016;18:501-7.
    • (2016) Nicotine Tob Res , vol.18 , pp. 501-507
    • Palipudi, K.M.1    Mbulo, L.2
  • 66
    • 79960510296 scopus 로고    scopus 로고
    • In vitro celxposure studies for the assessment of nanoparticle toxicity in the lung—ialog between aerosol science and biology
    • Paur H-R, Cassee FR, Teeguarden J, et al. In vitro celxposure studies for the assessment of nanoparticle toxicity in the lung—ialog between aerosol science and biology. J Aerosol Sci. 2011;42:668-92.
    • (2011) J Aerosol Sci , vol.42 , pp. 668-692
    • Paur, H.-R.1    Cassee, F.R.2    Teeguarden, J.3
  • 67
    • 84906272344 scopus 로고    scopus 로고
    • Electronic nicotinelivery system (Electronic cigarette) awareness, use, reactions and beliefs: A systematic review
    • Pepper J, Brewer N. Electronic nicotinelivery system (electronic cigarette) awareness, use, reactions and beliefs: a systematic review. Tob Control. 2014;23:375-84.
    • (2014) Tob Control , vol.23 , pp. 375-384
    • Pepper, J.1    Brewer, N.2
  • 68
    • 21844451174 scopus 로고    scopus 로고
    • Exposure oronchiapithelial cells to whole cigarette smoke: Assessment of cellular responses
    • Phillips J, Kluss B, Richter A, Massey ED. Exposure oronchiapithelial cells to whole cigarette smoke: assessment of cellular responses. Altern lab Anim. 2005;33:239-48.
    • (2005) Altern Lab Anim , vol.33 , pp. 239-248
    • Phillips, J.1    Kluss, B.2    Richter, A.3    Massey, E.D.4
  • 69
    • 84967318067 scopus 로고    scopus 로고
    • Simulation of aerosoynamics and deposition of combustible and electronic cigarette aerosols in the human respiratory tract
    • Pichelstorfer L, Hofmann W, Winkler-Heil R, et al. Simulation of aerosoynamics and deposition of combustible and electronic cigarette aerosols in the human respiratory tract. J Aerosol Sci. 2016;99:125-32.
    • (2016) J Aerosol Sci , vol.99 , pp. 125-132
    • Pichelstorfer, L.1    Hofmann, W.2    Winkler-Heil, R.3
  • 70
    • 84953723351 scopus 로고    scopus 로고
    • Cytotoxivaluation o-liquid aerososing different lung derived cell models
    • Polosa R, Caruso M, Guarino F. Comments on Schefflet al. cytotoxivaluation o-liquid aerososing different lung derived cell models. Int J Environ Res Public Health. 2016;13:108.
    • (2016) Int J Environ Res Public Health , vol.13 , pp. 108
    • Polosa, R.1    Caruso, M.2    Guarino, F.3
  • 71
    • 85046849126 scopus 로고    scopus 로고
    • Public Health England. 2015. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/457102/Ecigarettes_an_evidence:update_A_report_commissioned_by_Public_Health_England_FINAL.pdf
    • (2015)
  • 72
    • 84876313707 scopus 로고    scopus 로고
    • Effect of puffing intensity on cigarette smoke yields
    • Purkis SW, Troude V, Hill CA. Effect of puffing intensity on cigarette smoke yields. Regul Toxicoharmacol. 2013;66:72-82.
    • (2013) Regul Toxicoharmacol , vol.66 , pp. 72-82
    • Purkis, S.W.1    Troude, V.2    Hill, C.A.3
  • 73
    • 33947214401 scopus 로고    scopus 로고
    • Effect of smoking conditions and methods of collection on the mutagenicity and cytotoxicity of cigarette mainstream smoke
    • Rickert WS, Trivedi AH, Momin RA, et al. Effect of smoking conditions and methods of collection on the mutagenicity and cytotoxicity of cigarette mainstream smoke. Toxicol Sci. 2007;96:285-93.
    • (2007) Toxicol Sci , vol.96 , pp. 285-293
    • Rickert, W.S.1    Trivedi, A.H.2    Momin, R.A.3
  • 75
    • 33846704825 scopus 로고    scopus 로고
    • Tobacco harm reduction: An alternative cessation strategy for inveterate smokers
    • Rodu B, Godshall WT. Tobacco harm reduction: an alternative cessation strategy for inveterate smokers. Harm Reduct J. 2006;3:37.
    • (2006) Harm Reduct J , vol.3 , pp. 37
    • Rodu, B.1    Godshall, W.T.2
  • 76
    • 84878929968 scopus 로고    scopus 로고
    • Cytotoxicity evaluation olectronic cigarette vapoxtract on cultured mammalian fibroblasts (ClearStream-LIFE): Comparison with tobacco cigarette smokxtract
    • Romagna G, Allifranchini E, Bocchietto E, et al. Cytotoxicity evaluation olectronic cigarette vapoxtract on cultured mammalian fibroblasts (ClearStream-LIFE): comparison with tobacco cigarette smokxtract. Inhal Toxicol. 2013;25:354-61.
    • (2013) Inhal Toxicol , vol.25 , pp. 354-361
    • Romagna, G.1    Allifranchini, E.2    Bocchietto, E.3
  • 77
    • 85046840226 scopus 로고    scopus 로고
    • Royal College ohysicians. 2016. https://www.rcplondon.ac.uk/sites/default/files/media/Documents/Nicotine%20without%20smoke_0.pdf?token=uV0R0Twz
    • (2016)
  • 78
    • 84872900264 scopus 로고    scopus 로고
    • Particle sizistribution of mainstream and exhaled cigarette smoke and predictiveposition in human respiratory tract
    • Sahu SK, Tiwar D, Bhangare RC, Pandit GG. Particle sizistribution of mainstream and exhaled cigarette smoke and predictiveposition in human respiratory tract. Aerosol Air Qual Res. 2013;13:324-32.
    • (2013) Aerosol Air Qual Res , vol.13 , pp. 324-332
    • Sahu, S.K.1    Tiwar, D.2    Bhangare, R.C.3    Pandit, G.G.4
  • 79
    • 80053536589 scopus 로고    scopus 로고
    • Lung injury after cigarette smoking is particle related
    • Sangani RG, Ghio AJ. Lung injury after cigarette smoking is particle related. Int J Chron Obstruculmon Dis. 2011;6:191-8.
    • (2011) Int J Chron Obstruculmon Dis , vol.6 , pp. 191-198
    • Sangani, R.G.1    Ghio, A.J.2
  • 80
    • 84943572605 scopus 로고    scopus 로고
    • Aufderheid. Cytotoxivaluation o-liquid aerososing different lung-derived cell models
    • Scheffler S, Dieken H, Krischenowski O, Aufderheid. Cytotoxivaluation o-liquid aerososing different lung-derived cell models. Int J Environ Res Public Health. 2015;12:12466-74.
    • (2015) Int J Environ Res Public Health , vol.12 , pp. 12466-12474
    • Scheffler, S.1    Dieken, H.2    Krischenowski, O.3
  • 81
    • 84943572605 scopus 로고    scopus 로고
    • Cytotoxic Evaluation of E-Liquid Aerosol Using Different Lung Derived Celodels
    • Int J Environ Res Public Health. 2016;13:109
    • Scheffler S, Dieken H, Krischenowski O, Aufderheid. Response to Polost al. Comments on Schefflet al. Cytotoxic Evaluation of E-Liquid Aerosol Using Different Lung Derived Celodels. Int. J. Environ. Res. Public Health, 2015, 12, 12466-12474. Int J Environ Res Public Health. 2016;13:109. doi: 10.3390/ijerph13010109.
    • (2015) Int. J. Environ. Res. Public Health , vol.12 , pp. 12466-12474
    • Scheffler, S.1    Dieken, H.2    Krischenowski, O.3
  • 82
    • 84945916683 scopus 로고    scopus 로고
    • Roflumilast partially reverses smoke-induced mucociliary dysfunction
    • Schmid A, Baumlin N, Ivonne D, et al. Roflumilast partially reverses smoke-induced mucociliary dysfunction. Respir Res. 2015;16:135.
    • (2015) Respir Res , vol.16 , pp. 135
    • Schmid, A.1    Baumlin, N.2    Ivonne, D.3
  • 84
    • 85046845867 scopus 로고    scopus 로고
    • Electronic cigarettes and nicotine clinical pharmacology
    • Schroede J, Hoffman AC. Electronic cigarettes and nicotine clinical pharmacology. Tob Control. 2014;23:230-5.
    • (2014) Tob Control , vol.23 , pp. 230-235
    • Schroede, J.1    Hoffman, A.C.2
  • 85
    • 84937404195 scopus 로고    scopus 로고
    • Endotheliaisruptive proinflammatory effects of nicotine and e-cigarette vapoxposures
    • Schweitzer K, Chen S, Law S, et al. Endotheliaisruptive proinflammatory effects of nicotine and e-cigarette vapoxposures. Am J Physiology Lung Celohysiol. 2015;309:175-87.
    • (2015) Am J Physiology Lung Celohysiol , vol.309 , pp. 175-187
    • Schweitzer, K.1    Chen, S.2    Law, S.3
  • 87
    • 84957429603 scopus 로고    scopus 로고
    • Nicotinelivery, retention and pharmacokinetics from various electronic cigarettes
    • St Helen G, Havel C, Dempsey DA, et al. Nicotinelivery, retention and pharmacokinetics from various electronic cigarettes. Addiction. 2016;111:535-44.
    • (2016) Addiction , vol.111 , pp. 535-544
    • St Helen, G.1    Havel, C.2    Dempsey, D.A.3
  • 88
    • 84885849228 scopus 로고    scopus 로고
    • A review of in vitro cigarette smokxposure systems
    • Thorne D, Adamson J. A review of in vitro cigarette smokxposure systems. Exp Toxicoathol. 2013;65:1183-93.
    • (2013) Exp Toxicoathol , vol.65 , pp. 1183-1193
    • Thorne, D.1    Adamson, J.2
  • 89
    • 84947039500 scopus 로고    scopus 로고
    • A comparative assessment of cigarette smoke aerosols using an in vitro air-liquid interface cytotoxicity test
    • Thorne D, Dalrymple A, Dillon D, et al. A comparative assessment of cigarette smoke aerosols using an in vitro air-liquid interface cytotoxicity test. Inhal Toxicol. 2015;27:629-40.
    • (2015) Inhal Toxicol , vol.27 , pp. 629-640
    • Thorne, D.1    Dalrymple, A.2    Dillon, D.3
  • 90
    • 58649097010 scopus 로고    scopus 로고
    • Measurement of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmonary carcinoma cells
    • Thorne D, Wilson J, Kumaravel TS, et al. Measurement of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmonary carcinoma cells. Mutat Res. 2009;673:3-8.
    • (2009) Mutat Res , vol.673 , pp. 3-8
    • Thorne, D.1    Wilson, J.2    Kumaravel, T.S.3
  • 91
    • 85046854527 scopus 로고    scopus 로고
    • University of Kentucky: 3R4F reference cigarette. Available from: https://ctrp.uky.edu/resources/pdf/webdocs/3R4F%20Preliminary%20Analysis.pdf [last accessed 1 June 2016].
  • 92
    • 84920265856 scopus 로고    scopus 로고
    • Transforming growth factor-b1 and cigarette smoke inhibit the ability o2-agonists to enhancpithelial permeability
    • Unwalla H, Ivonne, Dennis JS, et al. Transforming growth factor-b1 and cigarette smoke inhibit the ability o2-agonists to enhancpithelial permeability. Am J Respir Celol Biol. 2015;52:65-74.
    • (2015) Am J Respir Celol Biol , vol.52 , pp. 65-74
    • Unwalla, H.1    Ivonne, Dennis, J.S.2
  • 95
    • 85046865386 scopus 로고    scopus 로고
    • Vitrocell. VC10 Smoking Robot. Available from: http://www.vitrocell.com/inhalation-toxicology/smoking-machines/vc-10 [last accessed 1 June 2016].
  • 97
    • 85046883920 scopus 로고    scopus 로고
    • World Health Organization. 2008. http://apps.who.int/iris/bitstream/10665/43997/1/TRS951_eng.pdf?ua=1
    • (2008)
  • 98
    • 84875165218 scopus 로고    scopus 로고
    • Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol
    • Williams M, Villarreal A, Bozhilov K, et al. Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol. PLoS One. 2013;8:e57987.
    • (2013) Plos One , vol.8
    • Williams, M.1    Villarreal, A.2    Bozhilov, K.3
  • 99
    • 84962388369 scopus 로고    scopus 로고
    • Electronic cigarettes induce DNA strand breaks and celeath independently of nicotine in cell lines
    • Yu V, Rahimy M, Korrapati A, et al. Electronic cigarettes induce DNA strand breaks and celeath independently of nicotine in cell lines. Oral Oncol. 2016;52:58-65.
    • (2016) Oral Oncol , vol.52 , pp. 58-65
    • Yu, V.1    Rahimy, M.2    Korrapati, A.3


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