-
1
-
-
25444531712
-
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
-
Lau, S.K.; Woo, P.C.; Li, K.S.; Huang, Y.; Tsoi, H.W.; Wong, B.H.; Wong, S.S.; Leung, S.Y.; Chan, K.H.; Yuen, K.Y. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc. Natl. Acad. Sci. USA 2005, 102, 14040–14045. [CrossRef] [PubMed]
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14040-14045
-
-
Lau, S.K.1
Woo, P.C.2
Li, K.S.3
Huang, Y.4
Tsoi, H.W.5
Wong, B.H.6
Wong, S.S.7
Leung, S.Y.8
Chan, K.H.9
Yuen, K.Y.10
-
2
-
-
67650494311
-
Geographic dependence, surveillance, and origins of the 2009 influenza A (H1N1) virus
-
Trifonov, V.; Khiabanian, H.; Rabadan, R. Geographic dependence, surveillance, and origins of the 2009 influenza A (H1N1) virus. N. Engl. J. Med. 2009, 361, 115–119. [CrossRef] [PubMed]
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 115-119
-
-
Trifonov, V.1
Khiabanian, H.2
Rabadan, R.3
-
3
-
-
84907193791
-
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
-
Gire, S.K.; Goba, A.; Andersen, K.G.; Sealfon, R.S.; Park, D.J.; Kanneh, L.; Jalloh, S.; Momoh, M.; Fullah, M.; Dudas, G.; et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science 2014, 345, 1369–1372. [CrossRef] [PubMed]
-
(2014)
Science
, vol.345
, pp. 1369-1372
-
-
Gire, S.K.1
Goba, A.2
Andersen, K.G.3
Sealfon, R.S.4
Park, D.J.5
Kanneh, L.6
Jalloh, S.7
Momoh, M.8
Fullah, M.9
Dudas, G.10
-
4
-
-
84907867765
-
Emergence of Zaire Ebola virus disease in Guinea
-
Baize, S.; Pannetier, D.; Oestereich, L.; Rieger, T.; Koivogui, L.; Magassouba, N.; Soropogui, B.; Sow, M.S.; Keita, S.; De Clerck, H.; et al. Emergence of Zaire Ebola virus disease in Guinea. N. Engl. J. Med. 2014, 371, 1418–1425. [CrossRef] [PubMed]
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 1418-1425
-
-
Baize, S.1
Pannetier, D.2
Oestereich, L.3
Rieger, T.4
Koivogui, L.5
Magassouba, N.6
Soropogui, B.7
Sow, M.S.8
Keita, S.9
de Clerck, H.10
-
5
-
-
84994851357
-
The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing
-
Snijder, E.J.; Decroly, E.; Ziebuhr, J. The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing. Adv. Virus Res. 2016, 96, 59–126. [PubMed]
-
(2016)
Adv. Virus Res.
, vol.96
, pp. 59-126
-
-
Snijder, E.J.1
Decroly, E.2
Ziebuhr, J.3
-
6
-
-
0019255091
-
Coronavirus infections of man associated with diseases other than the common cold
-
Riski, H.; Hovi, T. Coronavirus infections of man associated with diseases other than the common cold. J. Med. Virol. 1980, 6, 259–265. [CrossRef] [PubMed]
-
(1980)
J. Med. Virol.
, vol.6
, pp. 259-265
-
-
Riski, H.1
Hovi, T.2
-
7
-
-
84959851955
-
Middle East respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease
-
Chan, J.F.; Lau, S.K.; To, K.K.; Cheng, V.C.; Woo, P.C.; Yuen, K.Y. Middle East respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease. Clin. Microbiol. Rev. 2015, 28, 465–522. [CrossRef]
-
(2015)
Clin. Microbiol. Rev.
, vol.28
, pp. 465-522
-
-
Chan, J.F.1
Lau, S.K.2
To, K.K.3
Cheng, V.C.4
Woo, P.C.5
Yuen, K.Y.6
-
8
-
-
27344438916
-
Bats are natural reservoirs of SARS-like coronaviruses
-
Li, W.; Shi, Z.; Yu, M.; Ren, W.; Smith, C.; Epstein, J.H.; Wang, H.; Crameri, G.; Hu, Z.; Zhang, H.; et al. Bats are natural reservoirs of SARS-like coronaviruses. Science 2005, 310, 676–679. [CrossRef]
-
(2005)
Science
, vol.310
, pp. 676-679
-
-
Li, W.1
Shi, Z.2
Yu, M.3
Ren, W.4
Smith, C.5
Epstein, J.H.6
Wang, H.7
Crameri, G.8
Hu, Z.9
Zhang, H.10
-
9
-
-
85019158568
-
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
-
Anthony, S.J.; Gilardi, K.; Menachery, V.D.; Goldstein, T.; Ssebide, B.; Mbabazi, R.; Navarrete-Macias, I.; Liang, E.; Wells, H.; Hicks, A.; et al. Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus. mBio 2017, 8. [CrossRef]
-
(2017)
Mbio
, vol.8
-
-
Anthony, S.J.1
Gilardi, K.2
Menachery, V.D.3
Goldstein, T.4
Ssebide, B.5
Mbabazi, R.6
Navarrete-Macias, I.7
Liang, E.8
Wells, H.9
Hicks, A.10
-
10
-
-
84949623850
-
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
-
Menachery, V.D.; Yount, B.L., Jr.; Debbink, K.; Agnihothram, S.; Gralinski, L.E.; Plante, J.A.; Graham, R.L.; Scobey, T.; Ge, X.Y.; Donaldson, E.F.; et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat. Med. 2015, 21, 1508–1513. [CrossRef]
-
(2015)
Nat. Med.
, vol.21
, pp. 1508-1513
-
-
Menachery, V.D.1
Yount, B.L.2
Debbink, K.3
Agnihothram, S.4
Gralinski, L.E.5
Plante, J.A.6
Graham, R.L.7
Scobey, T.8
Ge, X.Y.9
Donaldson, E.F.10
-
11
-
-
84941413167
-
Middle East respiratory syndrome
-
Zumla, A.; Hui, D.S.; Perlman, S. Middle East respiratory syndrome. Lancet 2015, 386, 995–1007. [CrossRef]
-
(2015)
Lancet
, vol.386
, pp. 995-1007
-
-
Zumla, A.1
Hui, D.S.2
Perlman, S.3
-
12
-
-
84922417149
-
MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983–1997
-
Muller, M.A.; Corman, V.M.; Jores, J.; Meyer, B.; Younan, M.; Liljander, A.; Bosch, B.J.; Lattwein, E.; Hilali, M.; Musa, B.E.; et al. MERS coronavirus neutralizing antibodies in camels, Eastern Africa, 1983–1997. Emerg. Infect. Dis. 2014, 20, 2093–2095. [CrossRef] [PubMed]
-
(2014)
Emerg. Infect. Dis.
, vol.20
, pp. 2093-2095
-
-
Muller, M.A.1
Corman, V.M.2
Jores, J.3
Meyer, B.4
Younan, M.5
Liljander, A.6
Bosch, B.J.7
Lattwein, E.8
Hilali, M.9
Musa, B.E.10
-
13
-
-
84903435220
-
Evidence for camel-to-human transmission of MERS coronavirus
-
Azhar, E.I.; El-Kafrawy, S.A.; Farraj, S.A.; Hassan, A.M.; Al-Saeed, M.S.; Hashem, A.M.; Madani, T.A. Evidence for camel-to-human transmission of MERS coronavirus. N. Engl. J. Med. 2014, 370, 2499–2505. [CrossRef] [PubMed]
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 2499-2505
-
-
Azhar, E.I.1
El-Kafrawy, S.A.2
Farraj, S.A.3
Hassan, A.M.4
Al-Saeed, M.S.5
Hashem, A.M.6
Madani, T.A.7
-
14
-
-
85181553253
-
Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013
-
The Health Protection Agency (HPA) UK Novel Coronavirus Investigation Team. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill. 2013, 18, 20427.
-
(2013)
Euro Surveill
, vol.18
-
-
-
15
-
-
84957818744
-
Coronaviruses-drug discovery and therapeutic options
-
Zumla, A.; Chan, J.F.; Azhar, E.I.; Hui, D.S.; Yuen, K.Y. Coronaviruses-drug discovery and therapeutic options. Nat. Rev. Drug Discov. 2016, 15, 327–347. [CrossRef] [PubMed]
-
(2016)
Nat. Rev. Drug Discov.
, vol.15
, pp. 327-347
-
-
Zumla, A.1
Chan, J.F.2
Azhar, E.I.3
Hui, D.S.4
Yuen, K.Y.5
-
16
-
-
84902176510
-
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
-
Dyall, J.; Coleman, C.M.; Hart, B.J.; Venkataraman, T.; Holbrook, M.R.; Kindrachuk, J.; Johnson, R.F.; Olinger, G.G., Jr.; Jahrling, P.B.; Laidlaw, M.; et al. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob. Agents Chemother. 2014, 58, 4885–4893. [CrossRef] [PubMed]
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4885-4893
-
-
Dyall, J.1
Coleman, C.M.2
Hart, B.J.3
Venkataraman, T.4
Holbrook, M.R.5
Kindrachuk, J.6
Johnson, R.F.7
Olinger, G.G.8
Jahrling, P.B.9
Laidlaw, M.10
-
18
-
-
85014788827
-
Searching for animal models and potential target species for emerging pathogens: Experience gained from Middle East respiratory syndrome (MERS) coronavirus
-
Vergara-Alert, J.; Vidal, E.; Bensaid, A.; Segales, J. Searching for animal models and potential target species for emerging pathogens: Experience gained from Middle East respiratory syndrome (MERS) coronavirus. One Health 2017, 3, 34–40. [CrossRef]
-
(2017)
One Health
, vol.3
, pp. 34-40
-
-
Vergara-Alert, J.1
Vidal, E.2
Bensaid, A.3
Segales, J.4
-
19
-
-
84874996988
-
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
-
Raj, V.S.; Mou, H.; Smits, S.L.; Dekkers, D.H.; Muller, M.A.; Dijkman, R.; Muth, D.; Demmers, J.A.; Zaki, A.; Fouchier, R.A.; et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013, 495, 251–254. [CrossRef]
-
(2013)
Nature
, vol.495
, pp. 251-254
-
-
Raj, V.S.1
Mou, H.2
Smits, S.L.3
Dekkers, D.H.4
Muller, M.A.5
Dijkman, R.6
Muth, D.7
Demmers, J.A.8
Zaki, A.9
Fouchier, R.A.10
-
20
-
-
84925425797
-
Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection
-
Peck, K.M.; Cockrell, A.S.; Yount, B.L.; Scobey, T.; Baric, R.S.; Heise, M.T. Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection. J. Virol. 2015, 89, 4696–4699. [CrossRef]
-
(2015)
J. Virol.
, vol.89
, pp. 4696-4699
-
-
Peck, K.M.1
Cockrell, A.S.2
Yount, B.L.3
Scobey, T.4
Baric, R.S.5
Heise, M.T.6
-
21
-
-
84897500507
-
Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection
-
Cockrell, A.S.; Peck, K.M.; Yount, B.L.; Agnihothram, S.S.; Scobey, T.; Curnes, N.R.; Baric, R.S.; Heise, M.T. Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection. J. Virol. 2014, 88, 5195–5199. [CrossRef]
-
(2014)
J. Virol.
, vol.88
, pp. 5195-5199
-
-
Cockrell, A.S.1
Peck, K.M.2
Yount, B.L.3
Agnihothram, S.S.4
Scobey, T.5
Curnes, N.R.6
Baric, R.S.7
Heise, M.T.8
-
22
-
-
84892579594
-
Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus
-
Coleman, C.M.; Matthews, K.L.; Goicochea, L.; Frieman, M.B. Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus. J. Gen. Virol. 2014, 95 Pt 2, 408–412. [CrossRef]
-
(2014)
J. Gen. Virol
, vol.95
, pp. 408-412
-
-
Coleman, C.M.1
Matthews, K.L.2
Goicochea, L.3
Frieman, M.B.4
-
23
-
-
84999652028
-
A mouse model for MERS coronavirus-induced acute respiratory distress syndrome
-
Cockrell, A.S.; Yount, B.L.; Scobey, T.; Jensen, K.; Douglas, M.; Beall, A.; Tang, X.C.; Marasco, W.A.; Heise, M.T.; Baric, R.S. A mouse model for MERS coronavirus-induced acute respiratory distress syndrome. Nat. Microbiol. 2016, 2, 16226. [CrossRef] [PubMed]
-
(2016)
Nat. Microbiol.
, vol.2
-
-
Cockrell, A.S.1
Yount, B.L.2
Scobey, T.3
Jensen, K.4
Douglas, M.5
Beall, A.6
Tang, X.C.7
Marasco, W.A.8
Heise, M.T.9
Baric, R.S.10
-
24
-
-
84897480727
-
Rapid generation of a mouse model for Middle East respiratory syndrome
-
Zhao, J.; Li, K.; Wohlford-Lenane, C.; Agnihothram, S.S.; Fett, C.; Gale, M.J., Jr.; Baric, R.S.; Enjuanes, L.; Gallagher, T.; McCray, P.B., Jr.; et al. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc. Natl. Acad. Sci. USA 2014, 111, 4970–4975. [CrossRef] [PubMed]
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 4970-4975
-
-
Zhao, J.1
Li, K.2
Wohlford-Lenane, C.3
Agnihothram, S.S.4
Fett, C.5
Gale, M.J.6
Baric, R.S.7
Enjuanes, L.8
Gallagher, T.9
McCray, P.B.10
-
25
-
-
84937107017
-
Pre-and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
-
Pascal, K.E.; Coleman, C.M.; Mujica, A.O.; Kamat, V.; Badithe, A.; Fairhurst, J.; Hunt, C.; Strein, J.; Berrebi, A.; Sisk, J.M.; et al. Pre-and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proc. Natl. Acad. Sci. USA 2015, 112, 8738–8743. [CrossRef] [PubMed]
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 8738-8743
-
-
Pascal, K.E.1
Coleman, C.M.2
Mujica, A.O.3
Kamat, V.4
Badithe, A.5
Fairhurst, J.6
Hunt, C.7
Strein, J.8
Berrebi, A.9
Sisk, J.M.10
-
26
-
-
84953931577
-
Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease
-
Tao, X.; Garron, T.; Agrawal, A.S.; Algaissi, A.; Peng, B.H.; Wakamiya, M.; Chan, T.S.; Lu, L.; Du, L.; Jiang, S.; et al. Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease. J. Virol. 2016, 90, 57–67. [CrossRef] [PubMed]
-
(2016)
J. Virol.
, vol.90
, pp. 57-67
-
-
Tao, X.1
Garron, T.2
Agrawal, A.S.3
Algaissi, A.4
Peng, B.H.5
Wakamiya, M.6
Chan, T.S.7
Lu, L.8
Du, L.9
Jiang, S.10
-
27
-
-
85022165906
-
Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice
-
Li, K.; Wohlford-Lenane, C.L.; Channappanavar, R.; Park, J.E.; Earnest, J.T.; Bair, T.B.; Bates, A.M.; Brogden, K.A.; Flaherty, H.A.; Gallagher, T.; et al. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proc. Natl. Acad. Sci. USA 2017, 114, E3119–E3128. [CrossRef] [PubMed]
-
(2017)
Proc. Natl. Acad. Sci. USA
, vol.114
, pp. E3119-E3128
-
-
Li, K.1
Wohlford-Lenane, C.L.2
Channappanavar, R.3
Park, J.E.4
Earnest, J.T.5
Bair, T.B.6
Bates, A.M.7
Brogden, K.A.8
Flaherty, H.A.9
Gallagher, T.10
-
28
-
-
60749134643
-
The spike protein of SARS-CoV—A target for vaccine and therapeutic development
-
Du, L.; He, Y.; Zhou, Y.; Liu, S.; Zheng, B.J.; Jiang, S. The spike protein of SARS-CoV—A target for vaccine and therapeutic development. Nat. Rev. Microbiol. 2009, 7, 226–236. [CrossRef] [PubMed]
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 226-236
-
-
Du, L.1
He, Y.2
Zhou, Y.3
Liu, S.4
Zheng, B.J.5
Jiang, S.6
-
29
-
-
84901003129
-
Current advancements and potential strategies in the development of MERS-CoV vaccines
-
Zhang, N.; Jiang, S.; Du, L. Current advancements and potential strategies in the development of MERS-CoV vaccines. Expert Rev. Vaccines 2014, 13, 761–774. [CrossRef]
-
(2014)
Expert Rev. Vaccines
, vol.13
, pp. 761-774
-
-
Zhang, N.1
Jiang, S.2
Du, L.3
-
30
-
-
43649101455
-
The SARS-CoV nucleocapsid protein: A protein with multifarious activities
-
Surjit, M.; Lal, S.K. The SARS-CoV nucleocapsid protein: A protein with multifarious activities. Infect. Genet. Evolut. 2008, 8, 397–405. [CrossRef]
-
(2008)
Infect. Genet. Evolut.
, vol.8
, pp. 397-405
-
-
Surjit, M.1
Lal, S.K.2
-
31
-
-
84953438753
-
Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein
-
Chang, C.K.; Lo, S.C.; Wang, Y.S.; Hou, M.H. Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein. Drug Discov. Today 2016, 21, 562–572. [CrossRef]
-
(2016)
Drug Discov. Today
, vol.21
, pp. 562-572
-
-
Chang, C.K.1
Lo, S.C.2
Wang, Y.S.3
Hou, M.H.4
-
32
-
-
84908065761
-
Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein
-
Millet, J.K.; Whittaker, G.R. Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein. Proc. Natl. Acad. Sci. USA 2014, 111, 15214–15219. [CrossRef] [PubMed]
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 15214-15219
-
-
Millet, J.K.1
Whittaker, G.R.2
-
33
-
-
85030211862
-
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein
-
Li, W.; Hulswit, R.J.G.; Widjaja, I.; Raj, V.S.; McBride, R.; Peng, W.; Widagdo, W.; Tortorici, M.A.; van Dieren, B.; Lang, Y.; et al. Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein. Proc. Natl. Acad. Sci. USA 2017, 114, E8508–E8517. [CrossRef] [PubMed]
-
(2017)
Proc. Natl. Acad. Sci. USA
, vol.114
, pp. E8508-E8517
-
-
Li, W.1
Hulswit, R.J.G.2
Widjaja, I.3
Raj, V.S.4
McBride, R.5
Peng, W.6
Widagdo, W.7
Tortorici, M.A.8
van Dieren, B.9
Lang, Y.10
-
34
-
-
85028522287
-
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
-
Pallesen, J.; Wang, N.; Corbett, K.S.; Wrapp, D.; Kirchdoerfer, R.N.; Turner, H.L.; Cottrell, C.A.; Becker, M.M.; Wang, L.; Shi, W.; et al. Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. USA 2017, 114, E7348–E7357. [CrossRef] [PubMed]
-
(2017)
Proc. Natl. Acad. Sci. USA
, vol.114
, pp. E7348-E7357
-
-
Pallesen, J.1
Wang, N.2
Corbett, K.S.3
Wrapp, D.4
Kirchdoerfer, R.N.5
Turner, H.L.6
Cottrell, C.A.7
Becker, M.M.8
Wang, L.9
Shi, W.10
-
35
-
-
84899797757
-
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
-
Jiang, L.; Wang, N.; Zuo, T.; Shi, X.; Poon, K.M.; Wu, Y.; Gao, F.; Li, D.; Wang, R.; Guo, J.; et al. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci. Transl. Med. 2014, 6, 234ra59. [CrossRef] [PubMed]
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 234
-
-
Jiang, L.1
Wang, N.2
Zuo, T.3
Shi, X.4
Poon, K.M.5
Wu, Y.6
Gao, F.7
Li, D.8
Wang, R.9
Guo, J.10
-
36
-
-
84959516658
-
High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling
-
Irigoyen, N.; Firth, A.E.; Jones, J.D.; Chung, B.Y.; Siddell, S.G.; Brierley, I. High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling. PLoS Pathog. 2016, 12, e1005473. [CrossRef] [PubMed]
-
(2016)
Plos Pathog
, vol.12
-
-
Irigoyen, N.1
Firth, A.E.2
Jones, J.D.3
Chung, B.Y.4
Siddell, S.G.5
Brierley, I.6
-
37
-
-
3042714194
-
Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity
-
Buchholz, U.J.; Bukreyev, A.; Yang, L.; Lamirande, E.W.; Murphy, B.R.; Subbarao, K.; Collins, P.L. Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc. Natl. Acad. Sci. USA 2004, 101, 9804–9809. [CrossRef] [PubMed]
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9804-9809
-
-
Buchholz, U.J.1
Bukreyev, A.2
Yang, L.3
Lamirande, E.W.4
Murphy, B.R.5
Subbarao, K.6
Collins, P.L.7
-
38
-
-
84898978774
-
Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses
-
Agnihothram, S.; Gopal, R.; Yount, B.L., Jr.; Donaldson, E.F.; Menachery, V.D.; Graham, R.L.; Scobey, T.D.; Gralinski, L.E.; Denison, M.R.; Zambon, M.; et al. Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses. J. Infect. Dis. 2014, 209, 995–1006. [CrossRef] [PubMed]
-
(2014)
J. Infect. Dis.
, vol.209
, pp. 995-1006
-
-
Agnihothram, S.1
Gopal, R.2
Yount, B.L.3
Donaldson, E.F.4
Menachery, V.D.5
Graham, R.L.6
Scobey, T.D.7
Gralinski, L.E.8
Denison, M.R.9
Zambon, M.10
-
39
-
-
1842664185
-
Induction of SARS-nucleoprotein-specific immune response by use of DNA vaccine
-
Zhu, M.S.; Pan, Y.; Chen, H.Q.; Shen, Y.; Wang, X.C.; Sun, Y.J.; Tao, K.H. Induction of SARS-nucleoprotein-specific immune response by use of DNA vaccine. Immunol. Lett. 2004, 92, 237–243. [CrossRef] [PubMed]
-
(2004)
Immunol. Lett.
, vol.92
, pp. 237-243
-
-
Zhu, M.S.1
Pan, Y.2
Chen, H.Q.3
Shen, Y.4
Wang, X.C.5
Sun, Y.J.6
Tao, K.H.7
-
40
-
-
84905749274
-
T cell-mediated immune response to respiratory coronaviruses
-
Channappanavar, R.; Zhao, J.; Perlman, S. T cell-mediated immune response to respiratory coronaviruses. Immunol. Res. 2014, 59, 118–128. [CrossRef]
-
(2014)
Immunol. Res.
, vol.59
, pp. 118-128
-
-
Channappanavar, R.1
Zhao, J.2
Perlman, S.3
-
41
-
-
2442657856
-
T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS
-
Wang, Y.D.; Sin, W.Y.; Xu, G.B.; Yang, H.H.; Wong, T.Y.; Pang, X.W.; He, X.Y.; Zhang, H.G.; Ng, J.N.; Cheng, C.S.; et al. T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS. J. Virol. 2004, 78, 5612–5618. [CrossRef]
-
(2004)
J. Virol.
, vol.78
, pp. 5612-5618
-
-
Wang, Y.D.1
Sin, W.Y.2
Xu, G.B.3
Yang, H.H.4
Wong, T.Y.5
Pang, X.W.6
He, X.Y.7
Zhang, H.G.8
Ng, J.N.9
Cheng, C.S.10
-
42
-
-
85047337685
-
Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses
-
Zhao, J.; Alshukairi, A.N.; Baharoon, S.A.; Ahmed, W.A.; Bokhari, A.A.; Nehdi, A.M.; Layqah, L.A.; Alghamdi, M.G.; Al Gethamy, M.M.; Dada, A.M.; et al. Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses. Sci. Immunol. 2017, 2. [CrossRef] [PubMed]
-
(2017)
Sci. Immunol
, pp. 2
-
-
Zhao, J.1
Alshukairi, A.N.2
Baharoon, S.A.3
Ahmed, W.A.4
Bokhari, A.A.5
Nehdi, A.M.6
Layqah, L.A.7
Alghamdi, M.G.8
Al Gethamy, M.M.9
Dada, A.M.10
-
43
-
-
33845940452
-
Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants
-
Deming, D.; Sheahan, T.; Heise, M.; Yount, B.; Davis, N.; Sims, A.; Suthar, M.; Harkema, J.; Whitmore, A.; Pickles, R.; et al. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 2006, 3, e525. [CrossRef]
-
(2006)
Plos Med
, vol.3
-
-
Deming, D.1
Sheahan, T.2
Heise, M.3
Yount, B.4
Davis, N.5
Sims, A.6
Suthar, M.7
Harkema, J.8
Whitmore, A.9
Pickles, R.10
-
44
-
-
84859997825
-
Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus
-
Tseng, C.T.; Sbrana, E.; Iwata-Yoshikawa, N.; Newman, P.C.; Garron, T.; Atmar, R.L.; Peters, C.J.; Couch, R.B. Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PLoS ONE 2012, 7, e35421. [CrossRef]
-
(2012)
Plos ONE
, vol.7
-
-
Tseng, C.T.1
Sbrana, E.2
Iwata-Yoshikawa, N.3
Newman, P.C.4
Garron, T.5
Atmar, R.L.6
Peters, C.J.7
Couch, R.B.8
-
45
-
-
5644261220
-
Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface
-
Weihofen, W.A.; Liu, J.; Reutter, W.; Saenger, W.; Fan, H. Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J. Biol. Chem. 2004, 279, 43330–43335. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43330-43335
-
-
Weihofen, W.A.1
Liu, J.2
Reutter, W.3
Saenger, W.4
Fan, H.5
-
46
-
-
84982176821
-
MERS-CoV spike protein: Targets for vaccines and therapeutics
-
Wang, Q.; Wong, G.; Lu, G.; Yan, J.; Gao, G.F. MERS-CoV spike protein: Targets for vaccines and therapeutics. Antivir. Res. 2016, 133, 165–177. [CrossRef] [PubMed]
-
(2016)
Antivir. Res.
, vol.133
, pp. 165-177
-
-
Wang, Q.1
Wong, G.2
Lu, G.3
Yan, J.4
Gao, G.F.5
-
47
-
-
0033778518
-
Design and production of recombinant subunit vaccines
-
Hansson, M.; Nygren, P.A.; Stahl, S. Design and production of recombinant subunit vaccines. Biotechnol. Appl. Biochem. 2000, 32 (Pt 2), 95–107. [CrossRef] [PubMed]
-
(2000)
Biotechnol. Appl. Biochem
, vol.32
, pp. 95-107
-
-
Hansson, M.1
Nygren, P.A.2
Stahl, S.3
-
48
-
-
78049374354
-
Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients
-
Cao, Z.; Liu, L.; Du, L.; Zhang, C.; Jiang, S.; Li, T.; He, Y. Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients. Virol. J. 2010, 7, 299. [CrossRef]
-
(2010)
Virol. J.
, vol.7
, pp. 299
-
-
Cao, Z.1
Liu, L.2
Du, L.3
Zhang, C.4
Jiang, S.5
Li, T.6
He, Y.7
-
49
-
-
84883286587
-
Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development
-
Du, L.; Zhao, G.; Kou, Z.; Ma, C.; Sun, S.; Poon, V.K.; Lu, L.; Wang, L.; Debnath, A.K.; Zheng, B.J.; et al. Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development. J. Virol. 2013, 87, 9939–9942. [CrossRef]
-
(2013)
J. Virol.
, vol.87
, pp. 9939-9942
-
-
Du, L.1
Zhao, G.2
Kou, Z.3
Ma, C.4
Sun, S.5
Poon, V.K.6
Lu, L.7
Wang, L.8
Debnath, A.K.9
Zheng, B.J.10
-
50
-
-
84881232247
-
The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
-
Mou, H.; Raj, V.S.; van Kuppeveld, F.J.; Rottier, P.J.; Haagmans, B.L.; Bosch, B.J. The receptor binding domain of the new Middle East respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies. J. Virol. 2013, 87, 9379–9383. [CrossRef]
-
(2013)
J. Virol.
, vol.87
, pp. 9379-9383
-
-
Mou, H.1
Raj, V.S.2
van Kuppeveld, F.J.3
Rottier, P.J.4
Haagmans, B.L.5
Bosch, B.J.6
-
51
-
-
0034712874
-
Antibody and virus: Binding and neutralization
-
Burton, D.R.; Williamson, R.A.; Parren, P.W. Antibody and virus: Binding and neutralization. Virology 2000, 270, 1–3. [CrossRef]
-
(2000)
Virology
, vol.270
, pp. 1-3
-
-
Burton, D.R.1
Williamson, R.A.2
Parren, P.W.3
-
52
-
-
84896545485
-
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines
-
Ma, C.; Li, Y.; Wang, L.; Zhao, G.; Tao, X.; Tseng, C.T.; Zhou, Y.; Du, L.; Jiang, S. Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines. Vaccine 2014, 32, 2100–2108. [CrossRef] [PubMed]
-
(2014)
Vaccine
, vol.32
, pp. 2100-2108
-
-
Ma, C.1
Li, Y.2
Wang, L.3
Zhao, G.4
Tao, X.5
Tseng, C.T.6
Zhou, Y.7
Du, L.8
Jiang, S.9
-
53
-
-
58249100316
-
Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: Possible role of the prolonged half-life of the immunogen
-
Zhang, M.Y.; Wang, Y.; Mankowski, M.K.; Ptak, R.G.; Dimitrov, D.S. Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: Possible role of the prolonged half-life of the immunogen. Vaccine 2009, 27, 857–863. [CrossRef] [PubMed]
-
(2009)
Vaccine
, vol.27
, pp. 857-863
-
-
Zhang, M.Y.1
Wang, Y.2
Mankowski, M.K.3
Ptak, R.G.4
Dimitrov, D.S.5
-
54
-
-
84908010173
-
Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design
-
Ma, C.; Wang, L.; Tao, X.; Zhang, N.; Yang, Y.; Tseng, C.K.; Li, F.; Zhou, Y.; Jiang, S.; Du, L. Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design. Vaccine 2014, 32, 6170–6176. [CrossRef] [PubMed]
-
(2014)
Vaccine
, vol.32
, pp. 6170-6176
-
-
Ma, C.1
Wang, L.2
Tao, X.3
Zhang, N.4
Yang, Y.5
Tseng, C.K.6
Li, F.7
Zhou, Y.8
Jiang, S.9
Du, L.10
-
55
-
-
85042424089
-
Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen
-
Nyon, M.P.; Du, L.; Tseng, C.K.; Seid, C.A.; Pollet, J.; Naceanceno, K.S.; Agrawal, A.; Algaissi, A.; Peng, B.H.; Tai, W.; et al. Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen. Vaccine 2018, 36, 1853–1862. [CrossRef] [PubMed]
-
(2018)
Vaccine
, vol.36
, pp. 1853-1862
-
-
Nyon, M.P.1
Du, L.2
Tseng, C.K.3
Seid, C.A.4
Pollet, J.5
Naceanceno, K.S.6
Agrawal, A.7
Algaissi, A.8
Peng, B.H.9
Tai, W.10
-
56
-
-
0033160840
-
The carboxy-terminal domain initiates trimerization of bacteriophage T4 fibritin
-
Letarov, A.V.; Londer, Y.Y.; Boudko, S.P.; Mesyanzhinov, V.V. The carboxy-terminal domain initiates trimerization of bacteriophage T4 fibritin. Biochem. Biokhimiia 1999, 64, 817–823.
-
(1999)
Biochem. Biokhimiia
, vol.64
, pp. 817-823
-
-
Letarov, A.V.1
Londer, Y.Y.2
Boudko, S.P.3
Mesyanzhinov, V.V.4
-
57
-
-
84991782470
-
A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (HDPP4) transgenic mice from MERS-CoV infection
-
Tai, W.; Zhao, G.; Sun, S.; Guo, Y.; Wang, Y.; Tao, X.; Tseng, C.K.; Li, F.; Jiang, S.; Du, L.; et al. A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection. Virology 2016, 499, 375–382. [CrossRef] [PubMed]
-
(2016)
Virology
, vol.499
, pp. 375-382
-
-
Tai, W.1
Zhao, G.2
Sun, S.3
Guo, Y.4
Wang, Y.5
Tao, X.6
Tseng, C.K.7
Li, F.8
Jiang, S.9
Du, L.10
-
58
-
-
84951906168
-
Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge
-
Lan, J.; Yao, Y.; Deng, Y.; Chen, H.; Lu, G.; Wang, W.; Bao, L.; Deng, W.; Wei, Q.; Gao, G.F.; et al. Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge. EBioMedicine 2015, 2, 1438–1446. [CrossRef]
-
(2015)
Ebiomedicine
, vol.2
, pp. 1438-1446
-
-
Lan, J.1
Yao, Y.2
Deng, Y.3
Chen, H.4
Lu, G.5
Wang, W.6
Bao, L.7
Deng, W.8
Wei, Q.9
Gao, G.F.10
-
59
-
-
85008214652
-
Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants
-
Tai, W.; Wang, Y.; Fett, C.A.; Zhao, G.; Li, F.; Perlman, S.; Jiang, S.; Zhou, Y.; Du, L. Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants. J. Virol. 2017, 91, e01651-16. [CrossRef]
-
(2017)
J. Virol.
, vol.91
-
-
Tai, W.1
Wang, Y.2
Fett, C.A.3
Zhao, G.4
Li, F.5
Perlman, S.6
Jiang, S.7
Zhou, Y.8
Du, L.9
-
60
-
-
84900416594
-
Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice
-
Coleman, C.M.; Liu, Y.V.; Mu, H.; Taylor, J.K.; Massare, M.; Flyer, D.C.; Smith, G.E.; Frieman, M.B. Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine 2014, 32, 3169–3174. [CrossRef]
-
(2014)
Vaccine
, vol.32
, pp. 3169-3174
-
-
Coleman, C.M.1
Liu, Y.V.2
Mu, H.3
Taylor, J.K.4
Massare, M.5
Flyer, D.C.6
Smith, G.E.7
Frieman, M.B.8
-
61
-
-
85013449789
-
MERS-CoV spike nanoparticles protect mice from MERS-CoV infection
-
Coleman, C.M.; Venkataraman, T.; Liu, Y.V.; Glenn, G.M.; Smith, G.E.; Flyer, D.C.; Frieman, M.B. MERS-CoV spike nanoparticles protect mice from MERS-CoV infection. Vaccine 2017, 35, 1586–1589. [CrossRef]
-
(2017)
Vaccine
, vol.35
, pp. 1586-1589
-
-
Coleman, C.M.1
Venkataraman, T.2
Liu, Y.V.3
Glenn, G.M.4
Smith, G.E.5
Flyer, D.C.6
Frieman, M.B.7
-
62
-
-
33845227481
-
Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro
-
Kam, Y.W.; Kien, F.; Roberts, A.; Cheung, Y.C.; Lamirande, E.W.; Vogel, L.; Chu, S.L.; Tse, J.; Guarner, J.; Zaki, S.R.; et al. Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro. Vaccine 2007, 25, 729–740. [CrossRef] [PubMed]
-
(2007)
Vaccine
, vol.25
, pp. 729-740
-
-
Kam, Y.W.1
Kien, F.2
Roberts, A.3
Cheung, Y.C.4
Lamirande, E.W.5
Vogel, L.6
Chu, S.L.7
Tse, J.8
Guarner, J.9
Zaki, S.R.10
-
63
-
-
84887277978
-
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
-
McLellan, J.S.; Chen, M.; Joyce, M.G.; Sastry, M.; Stewart-Jones, G.B.; Yang, Y.; Zhang, B.; Chen, L.; Srivatsan, S.; Zheng, A.; et al. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science 2013, 342, 592–598. [CrossRef] [PubMed]
-
(2013)
Science
, vol.342
, pp. 592-598
-
-
McLellan, J.S.1
Chen, M.2
Joyce, M.G.3
Sastry, M.4
Stewart-Jones, G.B.5
Yang, Y.6
Zhang, B.7
Chen, L.8
Srivatsan, S.9
Zheng, A.10
-
64
-
-
0037561920
-
Characterization of a novel coronavirus associated with severe acute respiratory syndrome
-
Rota, P.A.; Oberste, M.S.; Monroe, S.S.; Nix, W.A.; Campagnoli, R.; Icenogle, J.P.; Penaranda, S.; Bankamp, B.; Maher, K.; Chen, M.H.; et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 2003, 300, 1394–1399. [CrossRef] [PubMed]
-
(2003)
Science
, vol.300
, pp. 1394-1399
-
-
Rota, P.A.1
Oberste, M.S.2
Monroe, S.S.3
Nix, W.A.4
Campagnoli, R.5
Icenogle, J.P.6
Penaranda, S.7
Bankamp, B.8
Maher, K.9
Chen, M.H.10
-
65
-
-
84999816148
-
The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection
-
Jiaming, L.; Yanfeng, Y.; Yao, D.; Yawei, H.; Linlin, B.; Baoying, H.; Jinghua, Y.; Gao, G.F.; Chuan, Q.; Wenjie, T. The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Vaccine 2017, 35, 10–18. [CrossRef] [PubMed]
-
(2017)
Vaccine
, vol.35
, pp. 10-18
-
-
Jiaming, L.1
Yanfeng, Y.2
Yao, D.3
Yawei, H.4
Linlin, B.5
Baoying, H.6
Jinghua, Y.7
Gao, G.F.8
Chuan, Q.9
Wenjie, T.10
-
66
-
-
0031753867
-
Gene transfer into muscle by electroporation in vivo
-
Aihara, H.; Miyazaki, J. Gene transfer into muscle by electroporation in vivo. Nat. Biotechnol. 1998, 16, 867–870. [CrossRef] [PubMed]
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 867-870
-
-
Aihara, H.1
Miyazaki, J.2
-
67
-
-
79957781340
-
Electroporation delivery of DNA vaccines: Prospects for success
-
Sardesai, N.Y.; Weiner, D.B. Electroporation delivery of DNA vaccines: Prospects for success. Curr. Opin. Immunol. 2011, 23, 421–429. [CrossRef]
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 421-429
-
-
Sardesai, N.Y.1
Weiner, D.B.2
-
68
-
-
78650573649
-
DNA vaccines: An historical perspective and view to the future
-
Liu, M.A. DNA vaccines: An historical perspective and view to the future. Immunol. Rev. 2011, 239, 62–84. [CrossRef]
-
(2011)
Immunol. Rev.
, vol.239
, pp. 62-84
-
-
Liu, M.A.1
-
69
-
-
0029552275
-
Potential DNA vaccine integration into host cell genome
-
Nichols, W.W.; Ledwith, B.J.; Manam, S.V.; Troilo, P.J. Potential DNA vaccine integration into host cell genome. Ann. N. Y. Acad. Sci. 1995, 772, 30–39. [CrossRef]
-
(1995)
Ann. N. Y. Acad. Sci.
, vol.772
, pp. 30-39
-
-
Nichols, W.W.1
Ledwith, B.J.2
Manam, S.V.3
Troilo, P.J.4
-
70
-
-
33744790917
-
Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts
-
Sheets, R.L.; Stein, J.; Manetz, T.S.; Duffy, C.; Nason, M.; Andrews, C.; Kong, W.P.; Nabel, G.J.; Gomez, P.L. Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts. Toxicol. Sci. 2006, 91, 610–619. [CrossRef]
-
(2006)
Toxicol. Sci.
, vol.91
, pp. 610-619
-
-
Sheets, R.L.1
Stein, J.2
Manetz, T.S.3
Duffy, C.4
Nason, M.5
Andrews, C.6
Kong, W.P.7
Nabel, G.J.8
Gomez, P.L.9
-
71
-
-
84939810764
-
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
-
Muthumani, K.; Falzarano, D.; Reuschel, E.L.; Tingey, C.; Flingai, S.; Villarreal, D.O.; Wise, M.; Patel, A.; Izmirly, A.; Aljuaid, A.; et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Sci. Transl. Med. 2015, 7, 301ra132. [CrossRef]
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 301
-
-
Muthumani, K.1
Falzarano, D.2
Reuschel, E.L.3
Tingey, C.4
Flingai, S.5
Villarreal, D.O.6
Wise, M.7
Patel, A.8
Izmirly, A.9
Aljuaid, A.10
-
72
-
-
21644475386
-
A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates
-
Barouch, D.H.; Yang, Z.Y.; Kong, W.P.; Korioth-Schmitz, B.; Sumida, S.M.; Truitt, D.M.; Kishko, M.G.; Arthur, J.C.; Miura, A.; Mascola, J.R.; et al. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. J. Virol. 2005, 79, 8828–8834. [CrossRef] [PubMed]
-
(2005)
J. Virol.
, vol.79
, pp. 8828-8834
-
-
Barouch, D.H.1
Yang, Z.Y.2
Kong, W.P.3
Korioth-Schmitz, B.4
Sumida, S.M.5
Truitt, D.M.6
Kishko, M.G.7
Arthur, J.C.8
Miura, A.9
Mascola, J.R.10
-
73
-
-
84856189784
-
Robust immune response elicited by a novel and unique Mycobacterium tuberculosis protein using an optimized DNA/protein heterologous prime/boost protocol
-
Cayabyab, M.J.; Kashino, S.S.; Campos-Neto, A. Robust immune response elicited by a novel and unique Mycobacterium tuberculosis protein using an optimized DNA/protein heterologous prime/boost protocol. Immunology 2012, 135, 216–225. [CrossRef] [PubMed]
-
(2012)
Immunology
, vol.135
, pp. 216-225
-
-
Cayabyab, M.J.1
Kashino, S.S.2
Campos-Neto, A.3
-
74
-
-
84938149041
-
Evaluation of candidate vaccine approaches for MERS-CoV
-
Wang, L.; Shi, W.; Joyce, M.G.; Modjarrad, K.; Zhang, Y.; Leung, K.; Lees, C.R.; Zhou, T.; Yassine, H.M.; Kanekiyo, M.; et al. Evaluation of candidate vaccine approaches for MERS-CoV. Nat. Commun. 2015, 6, 7712. [CrossRef] [PubMed]
-
(2015)
Nat. Commun.
, vol.6
, pp. 7712
-
-
Wang, L.1
Shi, W.2
Joyce, M.G.3
Modjarrad, K.4
Zhang, Y.5
Leung, K.6
Lees, C.R.7
Zhou, T.8
Yassine, H.M.9
Kanekiyo, M.10
-
75
-
-
85016333549
-
DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice
-
Chi, H.; Zheng, X.; Wang, X.; Wang, C.; Wang, H.; Gai, W.; Perlman, S.; Yang, S.; Zhao, J.; Xia, X. DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice. Vaccine 2017, 35, 2069–2075. [CrossRef] [PubMed]
-
(2017)
Vaccine
, vol.35
, pp. 2069-2075
-
-
Chi, H.1
Zheng, X.2
Wang, X.3
Wang, C.4
Wang, H.5
Gai, W.6
Perlman, S.7
Yang, S.8
Zhao, J.9
Xia, X.10
-
76
-
-
0030175501
-
Mechanisms of antigen uptake for presentation
-
Lanzavecchia, A. Mechanisms of antigen uptake for presentation. Curr. Opin. Immunol. 1996, 8, 348–354. [CrossRef]
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 348-354
-
-
Lanzavecchia, A.1
-
77
-
-
85016136746
-
Immunogenicity of Candidate MERS-CoV DNA Vaccines Based on the Spike Protein
-
Al-Amri, S.S.; Abbas, A.T.; Siddiq, L.A.; Alghamdi, A.; Sanki, M.A.; Al-Muhanna, M.K.; Alhabbab, R.Y.; Azhar, E.I.; Li, X.; Hashem, A.M. Immunogenicity of Candidate MERS-CoV DNA Vaccines Based on the Spike Protein. Sci. Rep. 2017, 7, 44875. [CrossRef]
-
(2017)
Sci. Rep
, vol.7
-
-
Al-Amri, S.S.1
Abbas, A.T.2
Siddiq, L.A.3
Alghamdi, A.4
Sanki, M.A.5
Al-Muhanna, M.K.6
Alhabbab, R.Y.7
Azhar, E.I.8
Li, X.9
Hashem, A.M.10
-
78
-
-
0023733838
-
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
-
Stevens, T.L.; Bossie, A.; Sanders, V.M.; Fernandez-Botran, R.; Coffman, R.L.; Mosmann, T.R.; Vitetta, E.S. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature 1988, 334, 255–258. [CrossRef]
-
(1988)
Nature
, vol.334
, pp. 255-258
-
-
Stevens, T.L.1
Bossie, A.2
Sanders, V.M.3
Fernandez-Botran, R.4
Coffman, R.L.5
Mosmann, T.R.6
Vitetta, E.S.7
-
79
-
-
79957761310
-
Viral vectors as vaccine platforms: Deployment in sight
-
Rollier, C.S.; Reyes-Sandoval, A.; Cottingham, M.G.; Ewer, K.; Hill, A.V. Viral vectors as vaccine platforms: Deployment in sight. Curr. Opin. Immunol. 2011, 23, 377–382. [CrossRef]
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 377-382
-
-
Rollier, C.S.1
Reyes-Sandoval, A.2
Cottingham, M.G.3
Ewer, K.4
Hill, A.V.5
-
80
-
-
0031583842
-
Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: Expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo
-
Pushko, P.; Parker, M.; Ludwig, G.V.; Davis, N.L.; Johnston, R.E.; Smith, J.F. Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: Expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology 1997, 239, 389–401. [CrossRef]
-
(1997)
Virology
, vol.239
, pp. 389-401
-
-
Pushko, P.1
Parker, M.2
Ludwig, G.V.3
Davis, N.L.4
Johnston, R.E.5
Smith, J.F.6
-
81
-
-
85046897752
-
Development of a Broadly Accessible Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Platform
-
Agnihothram, S.; Menachery, V.D.; Yount, B.L., Jr.; Lindesmith, L.C.; Scobey, T.; Whitmore, A.; Schafer, A.; Heise, M.T.; Baric, R.S. Development of a Broadly Accessible Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Platform. J. Virol. 2018, 92, e00027-18. [CrossRef]
-
(2018)
J. Virol.
, vol.92
-
-
Agnihothram, S.1
Menachery, V.D.2
Yount, B.L.3
Lindesmith, L.C.4
Scobey, T.5
Whitmore, A.6
Schafer, A.7
Heise, M.T.8
Baric, R.S.9
-
82
-
-
84973517439
-
Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses
-
Zhao, J.; Mangalam, A.K.; Channappanavar, R.; Fett, C.; Meyerholz, D.K.; Agnihothram, S.; Baric, R.S.; David, C.S.; Perlman, S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity 2016, 44, 1379–1391. [CrossRef] [PubMed]
-
(2016)
Immunity
, vol.44
, pp. 1379-1391
-
-
Zhao, J.1
Mangalam, A.K.2
Channappanavar, R.3
Fett, C.4
Meyerholz, D.K.5
Agnihothram, S.6
Baric, R.S.7
David, C.S.8
Perlman, S.9
-
83
-
-
0026442276
-
Nonreplicating vaccinia vector efficiently expresses recombinant genes
-
Sutter, G.; Moss, B. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc. Natl. Acad. Sci. USA 1992, 89, 10847–10851. [CrossRef] [PubMed]
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10847-10851
-
-
Sutter, G.1
Moss, B.2
-
84
-
-
0035859306
-
Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques
-
Stittelaar, K.J.; Kuiken, T.; de Swart, R.L.; van Amerongen, G.; Vos, H.W.; Niesters, H.G.; van Schalkwijk, P.; van der Kwast, T.; Wyatt, L.S.; Moss, B.; et al. Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques. Vaccine 2001, 19, 3700–3709. [CrossRef]
-
(2001)
Vaccine
, vol.19
, pp. 3700-3709
-
-
Stittelaar, K.J.1
Kuiken, T.2
de Swart, R.L.3
van Amerongen, G.4
Vos, H.W.5
Niesters, H.G.6
van Schalkwijk, P.7
van der Kwast, T.8
Wyatt, L.S.9
Moss, B.10
-
85
-
-
84886937421
-
Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies
-
Song, F.; Fux, R.; Provacia, L.B.; Volz, A.; Eickmann, M.; Becker, S.; Osterhaus, A.D.; Haagmans, B.L.; Sutter, G. Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies. J. Virol. 2013, 87, 11950–11954. [CrossRef] [PubMed]
-
(2013)
J. Virol.
, vol.87
, pp. 11950-11954
-
-
Song, F.1
Fux, R.2
Provacia, L.B.3
Volz, A.4
Eickmann, M.5
Becker, S.6
Osterhaus, A.D.7
Haagmans, B.L.8
Sutter, G.9
-
86
-
-
84938151524
-
Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein
-
Volz, A.; Kupke, A.; Song, F.; Jany, S.; Fux, R.; Shams-Eldin, H.; Schmidt, J.; Becker, C.; Eickmann, M.; Becker, S.; et al. Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein. J. Virol. 2015, 89, 8651–8656. [CrossRef] [PubMed]
-
(2015)
J. Virol.
, vol.89
, pp. 8651-8656
-
-
Volz, A.1
Kupke, A.2
Song, F.3
Jany, S.4
Fux, R.5
Shams-Eldin, H.6
Schmidt, J.7
Becker, C.8
Eickmann, M.9
Becker, S.10
-
87
-
-
85046863894
-
Distribution and absence of generalized lesions in mice following single dose intramuscular inoculation of the vaccine candidate MVA-MERS-S
-
Langenmayer, M.C.; Lulf-Averhoff, A.T.; Adam-Neumair, S.; Fux, R.; Sutter, G.; Volz, A. Distribution and absence of generalized lesions in mice following single dose intramuscular inoculation of the vaccine candidate MVA-MERS-S. Biologicals 2018, 54, 58–62. [CrossRef] [PubMed]
-
(2018)
Biologicals
, vol.54
, pp. 58-62
-
-
Langenmayer, M.C.1
Lulf-Averhoff, A.T.2
Adam-Neumair, S.3
Fux, R.4
Sutter, G.5
Volz, A.6
-
88
-
-
84952932413
-
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
-
Haagmans, B.L.; van den Brand, J.M.; Raj, V.S.; Volz, A.; Wohlsein, P.; Smits, S.L.; Schipper, D.; Bestebroer, T.M.; Okba, N.; Fux, R.; et al. An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels. Science 2016, 351, 77–81. [CrossRef]
-
(2016)
Science
, vol.351
, pp. 77-81
-
-
Haagmans, B.L.1
van den Brand, J.M.2
Raj, V.S.3
Volz, A.4
Wohlsein, P.5
Smits, S.L.6
Schipper, D.7
Bestebroer, T.M.8
Okba, N.9
Fux, R.10
-
89
-
-
84887865083
-
Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine
-
Hammer, S.M.; Sobieszczyk, M.E.; Janes, H.; Karuna, S.T.; Mulligan, M.J.; Grove, D.; Koblin, B.A.; Buchbinder, S.P.; Keefer, M.C.; Tomaras, G.D.; et al. Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. N. Engl. J. Med. 2013, 369, 2083–2092. [CrossRef]
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 2083-2092
-
-
Hammer, S.M.1
Sobieszczyk, M.E.2
Janes, H.3
Karuna, S.T.4
Mulligan, M.J.5
Grove, D.6
Koblin, B.A.7
Buchbinder, S.P.8
Keefer, M.C.9
Tomaras, G.D.10
-
90
-
-
0032853699
-
Immune responses to adenovirus and adeno-associated virus in humans
-
Chirmule, N.; Propert, K.; Magosin, S.; Qian, Y.; Qian, R.; Wilson, J. Immune responses to adenovirus and adeno-associated virus in humans. Gene Ther. 1999, 6, 1574–1583. [CrossRef]
-
(1999)
Gene Ther
, vol.6
, pp. 1574-1583
-
-
Chirmule, N.1
Propert, K.2
Magosin, S.3
Qian, Y.4
Qian, R.5
Wilson, J.6
-
91
-
-
73949160519
-
International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials
-
Mast, T.C.; Kierstead, L.; Gupta, S.B.; Nikas, A.A.; Kallas, E.G.; Novitsky, V.; Mbewe, B.; Pitisuttithum, P.; Schechter, M.; Vardas, E.; et al. International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials. Vaccine 2010, 28, 950–957. [CrossRef]
-
(2010)
Vaccine
, vol.28
, pp. 950-957
-
-
Mast, T.C.1
Kierstead, L.2
Gupta, S.B.3
Nikas, A.A.4
Kallas, E.G.5
Novitsky, V.6
Mbewe, B.7
Pitisuttithum, P.8
Schechter, M.9
Vardas, E.10
-
92
-
-
1942456719
-
Specific antibodies modulate the interactions of adenovirus type 5 with dendritic cells
-
Mercier, S.; Rouard, H.; Delfau-Larue, M.H.; Eloit, M. Specific antibodies modulate the interactions of adenovirus type 5 with dendritic cells. Virology 2004, 322, 308–317. [CrossRef] [PubMed]
-
(2004)
Virology
, vol.322
, pp. 308-317
-
-
Mercier, S.1
Rouard, H.2
Delfau-Larue, M.H.3
Eloit, M.4
-
93
-
-
84907963799
-
Immunogenicity of an adenoviral-based Middle East Respiratory Syndrome coronavirus vaccine in BALB/c mice
-
Kim, E.; Okada, K.; Kenniston, T.; Raj, V.S.; AlHajri, M.M.; Farag, E.A.; AlHajri, F.; Osterhaus, A.D.; Haagmans, B.L.; Gambotto, A. Immunogenicity of an adenoviral-based Middle East Respiratory Syndrome coronavirus vaccine in BALB/c mice. Vaccine 2014, 32, 5975–5982. [CrossRef]
-
(2014)
Vaccine
, vol.32
, pp. 5975-5982
-
-
Kim, E.1
Okada, K.2
Kenniston, T.3
Raj, V.S.4
Alhajri, M.M.5
Farag, E.A.6
Alhajri, F.7
Osterhaus, A.D.8
Haagmans, B.L.9
Gambotto, A.10
-
94
-
-
84936205833
-
Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus
-
Guo, X.; Deng, Y.; Chen, H.; Lan, J.; Wang, W.; Zou, X.; Hung, T.; Lu, Z.; Tan, W. Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus. Immunology 2015, 145, 476–484. [CrossRef] [PubMed]
-
(2015)
Immunology
, vol.145
, pp. 476-484
-
-
Guo, X.1
Deng, Y.2
Chen, H.3
Lan, J.4
Wang, W.5
Zou, X.6
Hung, T.7
Lu, Z.8
Tan, W.9
-
95
-
-
33846857302
-
Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41
-
Lemiale, F.; Haddada, H.; Nabel, G.J.; Brough, D.E.; King, C.R.; Gall, J.G. Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41. Vaccine 2007, 25, 2074–2084. [CrossRef] [PubMed]
-
(2007)
Vaccine
, vol.25
, pp. 2074-2084
-
-
Lemiale, F.1
Haddada, H.2
Nabel, G.J.3
Brough, D.E.4
King, C.R.5
Gall, J.G.6
-
96
-
-
85046705063
-
Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus
-
Jung, S.Y.; Kang, K.W.; Lee, E.Y.; Seo, D.W.; Kim, H.L.; Kim, H.; Kwon, T.; Park, H.L.; Lee, S.M.; Nam, J.H. Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus. Vaccine 2018, 36, 3468–3476. [CrossRef] [PubMed]
-
(2018)
Vaccine
, vol.36
, pp. 3468-3476
-
-
Jung, S.Y.1
Kang, K.W.2
Lee, E.Y.3
Seo, D.W.4
Kim, H.L.5
Kim, H.6
Kwon, T.7
Park, H.L.8
Lee, S.M.9
Nam, J.H.10
-
97
-
-
0035164962
-
Replication-defective vector based on a chimpanzee adenovirus
-
Farina, S.F.; Gao, G.P.; Xiang, Z.Q.; Rux, J.J.; Burnett, R.M.; Alvira, M.R.; Marsh, J.; Ertl, H.C.; Wilson, J.M. Replication-defective vector based on a chimpanzee adenovirus. J. Virol. 2001, 75, 11603–11613. [CrossRef]
-
(2001)
J. Virol.
, vol.75
, pp. 11603-11613
-
-
Farina, S.F.1
Gao, G.P.2
Xiang, Z.Q.3
Rux, J.J.4
Burnett, R.M.5
Alvira, M.R.6
Marsh, J.7
Ertl, H.C.8
Wilson, J.M.9
-
98
-
-
85018193995
-
Chimpanzee Adenovirus Vector Ebola Vaccine
-
Ledgerwood, J.E.; DeZure, A.D.; Stanley, D.A.; Coates, E.E.; Novik, L.; Enama, M.E.; Berkowitz, N.M.; Hu, Z.; Joshi, G.; Ploquin, A.; et al. Chimpanzee Adenovirus Vector Ebola Vaccine. N. Engl. J. Med. 2017, 376, 928–938. [CrossRef] [PubMed]
-
(2017)
N. Engl. J. Med.
, vol.376
, pp. 928-938
-
-
Ledgerwood, J.E.1
Dezure, A.D.2
Stanley, D.A.3
Coates, E.E.4
Novik, L.5
Enama, M.E.6
Berkowitz, N.M.7
Hu, Z.8
Joshi, G.9
Ploquin, A.10
-
99
-
-
85020128534
-
ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice
-
Alharbi, N.K.; Padron-Regalado, E.; Thompson, C.P.; Kupke, A.; Wells, D.; Sloan, M.A.; Grehan, K.; Temperton, N.; Lambe, T.; Warimwe, G.; et al. ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice. Vaccine 2017, 35, 3780–3788. [CrossRef]
-
(2017)
Vaccine
, vol.35
, pp. 3780-3788
-
-
Alharbi, N.K.1
Padron-Regalado, E.2
Thompson, C.P.3
Kupke, A.4
Wells, D.5
Sloan, M.A.6
Grehan, K.7
Temperton, N.8
Lambe, T.9
Warimwe, G.10
-
100
-
-
0032786615
-
Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences
-
Li, Z.; Howard, A.; Kelley, C.; Delogu, G.; Collins, F.; Morris, S. Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences. Infect. Immunity 1999, 67, 4780–4786.
-
(1999)
Infect. Immunity
, vol.67
, pp. 4780-4786
-
-
Li, Z.1
Howard, A.2
Kelley, C.3
Delogu, G.4
Collins, F.5
Morris, S.6
-
101
-
-
84938801542
-
Effects of the fusion design and immunization route on the immunogenicity of Ag85A-Mtb32 in adenoviral vectored tuberculosis vaccine
-
Zhang, Y.; Feng, L.; Li, L.; Wang, D.; Li, C.; Sun, C.; Li, P.; Zheng, X.; Liu, Y.; Yang, W. et al. Effects of the fusion design and immunization route on the immunogenicity of Ag85A-Mtb32 in adenoviral vectored tuberculosis vaccine. Hum. Vaccines Immunother. 2015, 11, 1803–1813. [CrossRef]
-
(2015)
Hum. Vaccines Immunother
, vol.11
, pp. 1803-1813
-
-
Zhang, Y.1
Feng, L.2
Li, L.3
Wang, D.4
Li, C.5
Sun, C.6
Li, P.7
Zheng, X.8
Liu, Y.9
Yang, W.10
-
102
-
-
85042178003
-
Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model
-
Munster, V.J.; Wells, D.; Lambe, T.; Wright, D.; Fischer, R.J.; Bushmaker, T.; Saturday, G.; van Doremalen, N.; Gilbert, S.C.; de Wit, E.; et al. Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model. NPJ Vaccines 2017, 2, 28. [CrossRef] [PubMed]
-
(2017)
NPJ Vaccines
, vol.2
, pp. 28
-
-
Munster, V.J.1
Wells, D.2
Lambe, T.3
Wright, D.4
Fischer, R.J.5
Bushmaker, T.6
Saturday, G.7
van Doremalen, N.8
Gilbert, S.C.9
de Wit, E.10
-
103
-
-
33947607350
-
Attenuated measles virus as a vaccine vector
-
Zuniga, A.; Wang, Z.; Liniger, M.; Hangartner, L.; Caballero, M.; Pavlovic, J.; Wild, P.; Viret, J.F.; Glueck, R.; Billeter, M.A.; et al. Attenuated measles virus as a vaccine vector. Vaccine 2007, 25, 2974–2983. [CrossRef] [PubMed]
-
(2007)
Vaccine
, vol.25
, pp. 2974-2983
-
-
Zuniga, A.1
Wang, Z.2
Liniger, M.3
Hangartner, L.4
Caballero, M.5
Pavlovic, J.6
Wild, P.7
Viret, J.F.8
Glueck, R.9
Billeter, M.A.10
-
104
-
-
84945911336
-
A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform
-
Malczyk, A.H.; Kupke, A.; Prufer, S.; Scheuplein, V.A.; Hutzler, S.; Kreuz, D.; Beissert, T.; Bauer, S.; Hubich-Rau, S.; Tondera, C.; et al. A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform. J. Virol. 2015, 89, 11654–11667. [CrossRef]
-
(2015)
J. Virol.
, vol.89
, pp. 11654-11667
-
-
Malczyk, A.H.1
Kupke, A.2
Prufer, S.3
Scheuplein, V.A.4
Hutzler, S.5
Kreuz, D.6
Beissert, T.7
Bauer, S.8
Hubich-Rau, S.9
Tondera, C.10
-
105
-
-
85048251583
-
Live-attenuated bivalent measles virus-derived vaccines targeting Middle East respiratory syndrome coronavirus induce robust and multifunctional T cell responses against both viruses in an appropriate mouse model
-
Bodmer, B.S.; Fiedler, A.H.; Hanauer, J.R.H.; Prufer, S.; Muhlebach, M.D. Live-attenuated bivalent measles virus-derived vaccines targeting Middle East respiratory syndrome coronavirus induce robust and multifunctional T cell responses against both viruses in an appropriate mouse model. Virology 2018, 521, 99–107. [CrossRef] [PubMed]
-
(2018)
Virology
, vol.521
, pp. 99-107
-
-
Bodmer, B.S.1
Fiedler, A.H.2
Hanauer, J.R.H.3
Prufer, S.4
Muhlebach, M.D.5
-
106
-
-
84977518046
-
Newcastle Disease Virus as a Vaccine Vector for Development of Human and Veterinary Vaccines
-
Kim, S.H.; Samal, S.K. Newcastle Disease Virus as a Vaccine Vector for Development of Human and Veterinary Vaccines. Viruses 2016, 8, 183. [CrossRef] [PubMed]
-
(2016)
Viruses
, vol.8
, pp. 183
-
-
Kim, S.H.1
Samal, S.K.2
-
107
-
-
85037986914
-
Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels
-
Liu, R.-Q.; Ge, J.-Y.; Wang, J.-L.; Yu, S.; Zhang, H.-L.; Wang, J.-L.; Wen, Z.-Y.; Bu, Z.-G. Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels. J. Integr. Agric. 2017, 16, 2264–2273. [CrossRef]
-
(2017)
J. Integr. Agric.
, vol.16
, pp. 2264-2273
-
-
Liu, R.-Q.1
Ge, J.-Y.2
Wang, J.-L.3
Yu, S.4
Zhang, H.-L.5
Wang, J.-L.6
Wen, Z.-Y.7
Bu, Z.-G.8
-
108
-
-
2342531185
-
Vesicular stomatitis virus: Re-inventing the bullet
-
Lichty, B.D.; Power, A.T.; Stojdl, D.F.; Bell, J.C. Vesicular stomatitis virus: Re-inventing the bullet. Trends Mol. Med. 2004, 10, 210–216. [CrossRef]
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 210-216
-
-
Lichty, B.D.1
Power, A.T.2
Stojdl, D.F.3
Bell, J.C.4
-
109
-
-
85038018275
-
A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunization
-
Liu, R.; Wang, J.; Shao, Y.; Wang, X.; Zhang, H.; Shuai, L.; Ge, J.; Wen, Z.; Bu, Z. A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunization. Antivir. Res. 2018, 150, 30–38. [CrossRef]
-
(2018)
Antivir. Res.
, vol.150
, pp. 30-38
-
-
Liu, R.1
Wang, J.2
Shao, Y.3
Wang, X.4
Zhang, H.5
Shuai, L.6
Ge, J.7
Wen, Z.8
Bu, Z.9
-
110
-
-
84943247429
-
Preclinical Development of Inactivated Rabies Virus-Based Polyvalent Vaccine Against Rabies and Filoviruses
-
Suppl. 2), S414–S424. [CrossRef
-
Willet, M.; Kurup, D.; Papaneri, A.; Wirblich, C.; Hooper, J.W.; Kwilas, S.A.; Keshwara, R.; Hudacek, A.; Beilfuss, S.; Rudolph, G.; et al. Preclinical Development of Inactivated Rabies Virus-Based Polyvalent Vaccine Against Rabies and Filoviruses. J. Infect. Dis. 2015, 212 (Suppl. 2), S414–S424. [CrossRef]
-
(2015)
J. Infect. Dis.
, vol.212
-
-
Willet, M.1
Kurup, D.2
Papaneri, A.3
Wirblich, C.4
Hooper, J.W.5
Kwilas, S.A.6
Keshwara, R.7
Hudacek, A.8
Beilfuss, S.9
Rudolph, G.10
-
111
-
-
85008689569
-
One-Health: A Safe, Efficient, Dual-Use Vaccine for Humans and Animals against Middle East Respiratory Syndrome Coronavirus and Rabies Virus
-
Wirblich, C.; Coleman, C.M.; Kurup, D.; Abraham, T.S.; Bernbaum, J.G.; Jahrling, P.B.; Hensley, L.E.; Johnson, R.F.; Frieman, M.B.; Schnell, M.J. One-Health: A Safe, Efficient, Dual-Use Vaccine for Humans and Animals against Middle East Respiratory Syndrome Coronavirus and Rabies Virus. J. Virol. 2017, 91, e02040-16. [CrossRef]
-
(2017)
J. Virol.
, vol.91
-
-
Wirblich, C.1
Coleman, C.M.2
Kurup, D.3
Abraham, T.S.4
Bernbaum, J.G.5
Jahrling, P.B.6
Hensley, L.E.7
Johnson, R.F.8
Frieman, M.B.9
Schnell, M.J.10
-
112
-
-
84871650149
-
Construction and characterization of virus-like particles: A review
-
Zeltins, A. Construction and characterization of virus-like particles: A review. Mol. Biotechnol. 2013, 53, 92–107. [CrossRef]
-
(2013)
Mol. Biotechnol.
, vol.53
, pp. 92-107
-
-
Zeltins, A.1
-
113
-
-
85013472962
-
MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques
-
Wang, C.; Zheng, X.; Gai, W.; Zhao, Y.; Wang, H.; Feng, N.; Chi, H.; Qiu, B.; Li, N.; Wang, T.; et al. MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques. Oncotarget 2017, 8, 12686–12694. [CrossRef] [PubMed]
-
(2017)
Oncotarget
, vol.8
, pp. 12686-12694
-
-
Wang, C.1
Zheng, X.2
Gai, W.3
Zhao, Y.4
Wang, H.5
Feng, N.6
Chi, H.7
Qiu, B.8
Li, N.9
Wang, T.10
-
114
-
-
85009968378
-
Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice
-
Wang, C.; Zheng, X.; Gai, W.; Wong, G.; Wang, H.; Jin, H.; Feng, N.; Zhao, Y.; Zhang, W.; Li, N.; et al. Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice. Antivir. Res. 2017, 140, 55–61. [CrossRef] [PubMed]
-
(2017)
Antivir. Res.
, vol.140
, pp. 55-61
-
-
Wang, C.1
Zheng, X.2
Gai, W.3
Wong, G.4
Wang, H.5
Jin, H.6
Feng, N.7
Zhao, Y.8
Zhang, W.9
Li, N.10
-
115
-
-
81255200507
-
A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge
-
Bolles, M.; Deming, D.; Long, K.; Agnihothram, S.; Whitmore, A.; Ferris, M.; Funkhouser, W.; Gralinski, L.; Totura, A.; Heise, M.; et al. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J. Virol. 2011, 85, 12201–12215. [CrossRef] [PubMed]
-
(2011)
J. Virol.
, vol.85
, pp. 12201-12215
-
-
Bolles, M.1
Deming, D.2
Long, K.3
Agnihothram, S.4
Whitmore, A.5
Ferris, M.6
Funkhouser, W.7
Gralinski, L.8
Totura, A.9
Heise, M.10
-
116
-
-
84987811156
-
Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus
-
Agrawal, A.S.; Tao, X.; Algaissi, A.; Garron, T.; Narayanan, K.; Peng, B.H.; Couch, R.B.; Tseng, C.T. Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus. Hum. Vaccines Immunother. 2016, 12, 2351–2356. [CrossRef] [PubMed]
-
(2016)
Hum. Vaccines Immunother.
, vol.12
, pp. 2351-2356
-
-
Agrawal, A.S.1
Tao, X.2
Algaissi, A.3
Garron, T.4
Narayanan, K.5
Peng, B.H.6
Couch, R.B.7
Tseng, C.T.8
-
117
-
-
85044961392
-
Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus
-
Deng, Y.; Lan, J.; Bao, L.; Huang, B.; Ye, F.; Chen, Y.; Yao, Y.; Wang, W.; Qin, C.; Tan, W. Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus. Emerg. Microbes Infect. 2018, 7, 60. [CrossRef]
-
(2018)
Emerg. Microbes Infect.
, vol.7
, pp. 60
-
-
Deng, Y.1
Lan, J.2
Bao, L.3
Huang, B.4
Ye, F.5
Chen, Y.6
Yao, Y.7
Wang, W.8
Qin, C.9
Tan, W.10
-
118
-
-
84903900023
-
Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine
-
Iwata-Yoshikawa, N.; Uda, A.; Suzuki, T.; Tsunetsugu-Yokota, Y.; Sato, Y.; Morikawa, S.; Tashiro, M.; Sata, T.; Hasegawa, H.; Nagata, N. Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine. J. Virol. 2014, 88, 8597–8614. [CrossRef]
-
(2014)
J. Virol.
, vol.88
, pp. 8597-8614
-
-
Iwata-Yoshikawa, N.1
Uda, A.2
Suzuki, T.3
Tsunetsugu-Yokota, Y.4
Sato, Y.5
Morikawa, S.6
Tashiro, M.7
Sata, T.8
Hasegawa, H.9
Nagata, N.10
-
119
-
-
17644390191
-
Vaccines: Past, present and future
-
Suppl. 4
-
Plotkin, S.A. Vaccines: Past, present and future. Nat. Med. 2005, 11 (Suppl. 4), S5–S11. [CrossRef]
-
(2005)
Nat. Med.
, vol.11
, pp. S5-S11
-
-
Plotkin, S.A.1
-
120
-
-
84858973962
-
The coronavirus E protein: Assembly and beyond
-
Ruch, T.R.; Machamer, C.E. The coronavirus E protein: Assembly and beyond. Viruses 2012, 4, 363–382. [CrossRef]
-
(2012)
Viruses
, vol.4
, pp. 363-382
-
-
Ruch, T.R.1
Machamer, C.E.2
-
121
-
-
47749117253
-
A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters
-
Lamirande, E.W.; DeDiego, M.L.; Roberts, A.; Jackson, J.P.; Alvarez, E.; Sheahan, T.; Shieh, W.J.; Zaki, S.R.; Baric, R.; Enjuanes, L.; et al. A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. J. Virol. 2008, 82, 7721–7724. [CrossRef]
-
(2008)
J. Virol.
, vol.82
, pp. 7721-7724
-
-
Lamirande, E.W.1
Dediego, M.L.2
Roberts, A.3
Jackson, J.P.4
Alvarez, E.5
Sheahan, T.6
Shieh, W.J.7
Zaki, S.R.8
Baric, R.9
Enjuanes, L.10
-
122
-
-
84887148359
-
Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate
-
Almazan, F.; DeDiego, M.L.; Sola, I.; Zuniga, S.; Nieto-Torres, J.L.; Marquez-Jurado, S.; Andres, G.; Enjuanes, L. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. mBio 2013, 4, e00650-13. [CrossRef] [PubMed]
-
(2013)
Mbio
, vol.4
, pp. 650
-
-
Almazan, F.1
Dediego, M.L.2
Sola, I.3
Zuniga, S.4
Nieto-Torres, J.L.5
Marquez-Jurado, S.6
Andres, G.7
Enjuanes, L.8
-
123
-
-
84870946428
-
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
-
Graham, R.L.; Becker, M.M.; Eckerle, L.D.; Bolles, M.; Denison, M.R.; Baric, R.S. A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nat. Med. 2012, 18, 1820–1826. [CrossRef] [PubMed]
-
(2012)
Nat. Med.
, vol.18
, pp. 1820-1826
-
-
Graham, R.L.1
Becker, M.M.2
Eckerle, L.D.3
Bolles, M.4
Denison, M.R.5
Baric, R.S.6
-
124
-
-
78751637122
-
′ -O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
-
′ -O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat. Immunol. 2011, 12, 137–143. [CrossRef] [PubMed]
-
(2011)
Nat. Immunol.
, vol.12
, pp. 137-143
-
-
Zust, R.1
Cervantes-Barragan, L.2
Habjan, M.3
Maier, R.4
Neuman, B.W.5
Ziebuhr, J.6
Szretter, K.J.7
Baker, S.C.8
Barchet, W.9
Diamond, M.S.10
-
125
-
-
84896981937
-
′ -o-methyltransferase activity
-
′ -o-methyltransferase activity. J. Virol. 2014, 88, 4251–4264. [CrossRef] [PubMed]
-
(2014)
J. Virol.
, vol.88
, pp. 4251-4264
-
-
Menachery, V.D.1
Yount, B.L.2
Josset, L.3
Gralinski, L.E.4
Scobey, T.5
Agnihothram, S.6
Katze, M.G.7
Baric, R.S.8
-
126
-
-
85051814705
-
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines
-
Menachery, V.D.; Gralinski, L.E.; Mitchell, H.D.; Dinnon, K.H., III; Leist, S.R.; Yount, B.L., Jr.; McAnarney, E.T.; Graham, R.L.; Waters, K.M.; Baric, R.S. Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines. J. Virol. 2018, 92, e00710-18. [CrossRef] [PubMed]
-
(2018)
J. Virol
, vol.92
, pp. e00710-e00718
-
-
Menachery, V.D.1
Gralinski, L.E.2
Mitchell, H.D.3
Dinnon, K.H.4
Leist, S.R.5
Yount, B.L.6
McAnarney, E.T.7
Graham, R.L.8
Waters, K.M.9
Baric, R.S.10
-
127
-
-
85041525335
-
Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis
-
Menachery, V.D.; Gralinski, L.E.; Mitchell, H.D.; Dinnon, K.H., III; Leist, S.R.; Yount, B.L., Jr.; Graham, R.L.; McAnarney, E.T.; Stratton, K.G.; Cockrell, A.S.; et al. Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis. mSphere 2017, 2, e00346-17. [CrossRef] [PubMed]
-
(2017)
Msphere
, vol.2
, pp. 346
-
-
Menachery, V.D.1
Gralinski, L.E.2
Mitchell, H.D.3
Dinnon, K.H.4
Leist, S.R.5
Yount, B.L.6
Graham, R.L.7
McAnarney, E.T.8
Stratton, K.G.9
Cockrell, A.S.10
-
128
-
-
84904545615
-
Accessory proteins of SARS-CoV and other coronaviruses
-
Liu, D.X.; Fung, T.S.; Chong, K.K.; Shukla, A.; Hilgenfeld, R. Accessory proteins of SARS-CoV and other coronaviruses. Antivir. Res. 2014, 109, 97–109. [CrossRef] [PubMed]
-
(2014)
Antivir. Res.
, vol.109
, pp. 97-109
-
-
Liu, D.X.1
Fung, T.S.2
Chong, K.K.3
Shukla, A.4
Hilgenfeld, R.5
-
129
-
-
85029156823
-
MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis
-
Menachery, V.D.; Mitchell, H.D.; Cockrell, A.S.; Gralinski, L.E.; Yount, B.L., Jr.; Graham, R.L.; McAnarney, E.T.; Douglas, M.G.; Scobey, T.; Beall, A.; et al. MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis. mBio 2017, 8. [CrossRef] [PubMed]
-
(2017)
Mbio
, vol.8
-
-
Menachery, V.D.1
Mitchell, H.D.2
Cockrell, A.S.3
Gralinski, L.E.4
Yount, B.L.5
Graham, R.L.6
McAnarney, E.T.7
Douglas, M.G.8
Scobey, T.9
Beall, A.10
-
131
-
-
84903730455
-
Calling for rapid development of a safe and effective MERS vaccine
-
Hotez, P.J.; Bottazzi, M.E.; Tseng, C.T.; Zhan, B.; Lustigman, S.; Du, L.; Jiang, S. Calling for rapid development of a safe and effective MERS vaccine. Microbes Infect. 2014, 16, 529–531. [CrossRef]
-
(2014)
Microbes Infect
, vol.16
, pp. 529-531
-
-
Hotez, P.J.1
Bottazzi, M.E.2
Tseng, C.T.3
Zhan, B.4
Lustigman, S.5
Du, L.6
Jiang, S.7
-
132
-
-
85041921699
-
Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques
-
Prescott, J.; Falzarano, D.; de Wit, E.; Hardcastle, K.; Feldmann, F.; Haddock, E.; Scott, D.; Feldmann, H.; Munster, V.J. Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques. Front. Immunol. 2018, 9, 205. [CrossRef]
-
(2018)
Front. Immunol.
, vol.9
, pp. 205
-
-
Prescott, J.1
Falzarano, D.2
de Wit, E.3
Hardcastle, K.4
Feldmann, F.5
Haddock, E.6
Scott, D.7
Feldmann, H.8
Munster, V.J.9
|