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Volumn 7, Issue 1, 2018, Pages

Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; INACTIVATED VIRUS VACCINE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS VACCINE; RECOMBINANT PROTEIN; RECOMBINANT S PROTEIN; UNCLASSIFIED DRUG; VIRUS SPIKE PROTEIN; VIRUS VACCINE; CORONAVIRUS SPIKE GLYCOPROTEIN; INACTIVATED VACCINE; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

EID: 85044961392     PISSN: None     EISSN: 22221751     Source Type: Journal    
DOI: 10.1038/s41426-018-0056-7     Document Type: Article
Times cited : (43)

References (43)
  • 2
    • 84871415482 scopus 로고    scopus 로고
    • Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans
    • van Boheemen, S. et al. Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. mBio 3, https://doi.org/10.1128/mBio.00473-12 (2012).
    • (2012) MBio , vol.3
    • Van Boheemen, S.1
  • 3
    • 84959851955 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease
    • Chan, J. F. et al. Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin. Microbiol. Rev. 28, 465-522 (2015).
    • (2015) Clin. Microbiol. Rev. , vol.28 , pp. 465-522
    • Chan, J.F.1
  • 4
    • 85017437709 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus vaccines: Current status and novel approaches
    • Okba, N. M., Raj, V. S. & Haagmans, B. L. Middle East respiratory syndrome coronavirus vaccines: current status and novel approaches. Curr. Opin. Virol. 23, 49-58 (2017).
    • (2017) Curr. Opin. Virol. , vol.23 , pp. 49-58
    • Okba, N.M.1    Raj, V.S.2    Haagmans, B.L.3
  • 5
    • 84977669592 scopus 로고    scopus 로고
    • A roadmap for MERS-CoV research and product development: Report from a World Health Organization consultation
    • Modjarrad, K. et al. A roadmap for MERS-CoV research and product development: report from a World Health Organization consultation. Nat. Med. 22, 701-705 (2016).
    • (2016) Nat. Med. , vol.22 , pp. 701-705
    • Modjarrad, K.1
  • 6
    • 84898978774 scopus 로고    scopus 로고
    • Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses
    • Agnihothram, S. et al. Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses. J. Infect. Dis. 209, 995-1006 (2014).
    • (2014) J. Infect. Dis. , vol.209 , pp. 995-1006
    • Agnihothram, S.1
  • 7
    • 84952932413 scopus 로고    scopus 로고
    • An orthopoxvirus-based vaccine reduces virus excretion after mers-cov infection in dromedary camels
    • Haagmans, B. L. et al. An orthopoxvirus-based vaccine reduces virus excretion after mers-cov infection in dromedary camels. Science 351, 77-81 (2016).
    • (2016) Science , vol.351 , pp. 77-81
    • Haagmans, B.L.1
  • 8
    • 85016333549 scopus 로고    scopus 로고
    • DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice
    • Chi, H. et al. DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice. Vaccine 35, 2069-2075 (2017).
    • (2017) Vaccine , vol.35 , pp. 2069-2075
    • Chi, H.1
  • 9
    • 84939810764 scopus 로고    scopus 로고
    • A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
    • Muthumani, K. et al. A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Sci. Transl. Med. 7, 301ra132 (2015).
    • (2015) Sci. Transl. Med. , vol.7 , pp. 301ra132
    • Muthumani, K.1
  • 10
    • 85013449789 scopus 로고    scopus 로고
    • MERS-CoV spike nanoparticles protect mice from MERSCoV infection
    • Coleman, C. M. et al. MERS-CoV spike nanoparticles protect mice from MERSCoV infection. Vaccine 35, 1586-1589 (2017).
    • (2017) Vaccine , vol.35 , pp. 1586-1589
    • Coleman, C.M.1
  • 11
    • 84938149041 scopus 로고    scopus 로고
    • Evaluation of candidate vaccine approaches for MERS-CoV
    • Wang, L. et al. Evaluation of candidate vaccine approaches for MERS-CoV. Nat. Commun. 6, 7712 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 7712
    • Wang, L.1
  • 12
    • 84881479703 scopus 로고    scopus 로고
    • Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
    • Lu, G. et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature 500, 227-231 (2013).
    • (2013) Nature , vol.500 , pp. 227-231
    • Lu, G.1
  • 13
    • 85014640544 scopus 로고    scopus 로고
    • Protective T cell responses featured by concordant recognition of middle east respiratory syndrome coronavirus-derived CD8+ T cell epitopes and host MHC
    • Liu, W. J. et al. Protective T cell responses featured by concordant recognition of middle east respiratory syndrome coronavirus-derived CD8+ T cell epitopes and host MHC. J. Immunol. 198, 873-882, https://doi.org/10.4049/jimmunol.1601542 (2017).
    • (2017) J. Immunol. , vol.198 , pp. 873-882
    • Liu, W.J.1
  • 14
    • 84991782470 scopus 로고    scopus 로고
    • A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection
    • Tai, W. et al. A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection. Virology 499, 375-382 (2016).
    • (2016) Virology , vol.499 , pp. 375-382
    • Tai, W.1
  • 15
    • 84913534501 scopus 로고    scopus 로고
    • Tailoring subunit vaccine immunity with adjuvant combinations and delivery routes using the Middle East respiratory coronavirus (MERS-CoV) receptor-binding domain as an antigen
    • Lan, J. et al. Tailoring subunit vaccine immunity with adjuvant combinations and delivery routes using the Middle East respiratory coronavirus (MERS-CoV) receptor-binding domain as an antigen. PLoS ONE 9, e112602 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e112602
    • Lan, J.1
  • 16
    • 84999816148 scopus 로고    scopus 로고
    • The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection
    • Jiaming, L. et al. The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Vaccine 35, 10-18 (2017).
    • (2017) Vaccine , vol.35 , pp. 10-18
    • Jiaming, L.1
  • 17
    • 84951906168 scopus 로고    scopus 로고
    • Recombinant receptor binding domain protein induces partial protective immunity in rhesus macaques against middle east respiratory syndrome coronavirus challenge
    • Lan, J. et al. Recombinant receptor binding domain protein induces partial protective immunity in rhesus macaques against middle east respiratory syndrome coronavirus challenge. EBioMedicine 2, 1438-1446 (2015).
    • (2015) EBioMedicine , vol.2 , pp. 1438-1446
    • Lan, J.1
  • 18
    • 84936205833 scopus 로고    scopus 로고
    • Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus
    • Gü, X. et al. Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus. Immunology 145, 476-484 (2015).
    • (2015) Immunology , vol.145 , pp. 476-484
    • Gü, X.1
  • 19
    • 84959905145 scopus 로고    scopus 로고
    • Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus
    • Zhang, N. et al. Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus. Cell. Mol. Immunol. 13, 180-190 (2015).
    • (2015) Cell. Mol. Immunol. , vol.13 , pp. 180-190
    • Zhang, N.1
  • 20
    • 84987811156 scopus 로고    scopus 로고
    • Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus
    • Agrawal A. S., et al. Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus. Human vaccines & immunotherapeutics, 1-6, https://doi.org/10.1080/21645515.2016.1177688 (2016).
    • (2016) Human Vaccines & Immunotherapeutics , pp. 1-6
    • Agrawal, A.S.1
  • 21
    • 81255200507 scopus 로고    scopus 로고
    • A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge
    • Bolles, M. et al. A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J. Virol. 85, 12201-12215 (2011).
    • (2011) J. Virol. , vol.85 , pp. 12201-12215
    • Bolles, M.1
  • 22
    • 84923169092 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology
    • Honda-Okubo, Y. et al. Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology. J. Virol. 89, 2995-3007 (2015).
    • (2015) J. Virol. , vol.89 , pp. 2995-3007
    • Honda-Okubo, Y.1
  • 23
    • 84903900023 scopus 로고    scopus 로고
    • Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALBc mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine
    • Iwata-Yoshikawa, N. et al. Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALBc mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine. J. Virol. 88, 8597-8614 (2014).
    • (2014) J. Virol. , vol.88 , pp. 8597-8614
    • Iwata-Yoshikawa, N.1
  • 24
    • 84859997825 scopus 로고    scopus 로고
    • Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus
    • Tseng, C. T. et al. Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PLoS ONE 7, e35421 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e35421
    • Tseng, C.T.1
  • 25
    • 33845940452 scopus 로고    scopus 로고
    • Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants
    • Deming, D. et al. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 3, e525 (2006).
    • (2006) PLoS Med. , vol.3 , pp. e525
    • Deming, D.1
  • 26
    • 58749104040 scopus 로고    scopus 로고
    • Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV
    • Yasui, F. et al. Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV. J. Immunol. 181, 6337-6348 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 6337-6348
    • Yasui, F.1
  • 27
    • 84893053165 scopus 로고    scopus 로고
    • Recent progress concerning CpG DNA and its use as a vaccine adjuvant
    • Shirota, H. & Klinman, D. M. Recent progress concerning CpG DNA and its use as a vaccine adjuvant. Expert Rev. Vaccin. 13, 299-312 (2014).
    • (2014) Expert Rev. Vaccin. , vol.13 , pp. 299-312
    • Shirota, H.1    Klinman, D.M.2
  • 28
    • 0014493282 scopus 로고
    • An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine
    • Kapikian, A. Z.,Mitchell, R. H., Chanock, R. M., Shvedoff, R. A. & Stewart, C. E. An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine. Am. J. Epidemiol. 89, 405 (1969).
    • (1969) Am. J. Epidemiol , vol.89 , pp. 405
    • Kapikian, A.Z.1    Mitchell, R.H.2    Chanock, R.M.3    Shvedoff, R.A.4    Stewart, C.E.5
  • 29
    • 84872409781 scopus 로고    scopus 로고
    • Poly(I:C)/alum mixed adjuvant priming enhances HBV subunit vaccine-induced immunity in mice when combined with recombinant adenoviral-based HBV vaccine boosting
    • Chuai, X. et al. Poly(I:C)/alum mixed adjuvant priming enhances HBV subunit vaccine-induced immunity in mice when combined with recombinant adenoviral-based HBV vaccine boosting. PLoS ONE 8, e54126 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e54126
    • Chuai, X.1
  • 30
    • 77954826894 scopus 로고    scopus 로고
    • Impact of different adjuvants on immunogenicity of the HBV particle vaccine containing the S + preS1 fusion antigen in Balb/C mice
    • Chen, H. et al. Impact of different adjuvants on immunogenicity of the HBV particle vaccine containing the S + preS1 fusion antigen in Balb/C mice. Chin. J. Biotechnol. 26, 74 (2010).
    • (2010) Chin. J. Biotechnol. , vol.26 , pp. 74
    • Chen, H.1
  • 31
    • 85019596455 scopus 로고    scopus 로고
    • A novel neutralizing monoclonal antibody targeting the Nterminal domain of the MERS-CoV spike protein
    • Chen, Y. et al. A novel neutralizing monoclonal antibody targeting the Nterminal domain of the MERS-CoV spike protein. Emerg. Microbes Infect. 6, e37 (2017).
    • (2017) Emerg. Microbes Infect. , vol.6 , pp. e37
    • Chen, Y.1
  • 32
    • 84914096998 scopus 로고    scopus 로고
    • Prokaryotic expression, purification and identification of the N protein of middle east respiratory syndrome coronavirus
    • Wang, Y. et al. Prokaryotic expression, purification and identification of the N protein of middle east respiratory syndrome coronavirus. Chinese Journal of Microbiology and Immunology 10, 764-769. (2014).
    • (2014) Chinese Journal of Microbiology and Immunology , vol.10 , pp. 764-769
    • Wang, Y.1
  • 33
    • 84886937421 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virusneutralizing antibodies
    • Song, F. et al. Middle East respiratory syndrome coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virusneutralizing antibodies. J. Virol. 87, 11950-11954 (2013).
    • (2013) J. Virol. , vol.87 , pp. 11950-11954
    • Song, F.1
  • 34
    • 85008893220 scopus 로고    scopus 로고
    • MERS-CoV spike protein: A key target for antivirals
    • Du, L. et al. MERS-CoV spike protein: a key target for antivirals. Expert Opin. Ther. Targets 21, 131-143 (2017).
    • (2017) Expert Opin. Ther. Targets , vol.21 , pp. 131-143
    • Du, L.1
  • 35
    • 33746289881 scopus 로고    scopus 로고
    • Long-lived memory T lymphocyte responses against SARS coronavirus nucleocapsid protein in SARS-recovered patients
    • Peng, H. et al. Long-lived memory T lymphocyte responses against SARS coronavirus nucleocapsid protein in SARS-recovered patients. Virology 351, 466-475 (2006).
    • (2006) Virology , vol.351 , pp. 466-475
    • Peng, H.1
  • 36
    • 5444256791 scopus 로고    scopus 로고
    • Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: Implications for the design of an effective protein-based vaccine
    • Pang, H. et al. Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine. J. Gen. Virol. 85, 3109-3113 (2004).
    • (2004) J. Gen. Virol. , vol.85 , pp. 3109-3113
    • Pang, H.1
  • 37
    • 3042714194 scopus 로고    scopus 로고
    • Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity
    • Buchholz, U. J. et al. Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc. Natl Acad. Sci. USA 101, 9804-9809 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 9804-9809
    • Buchholz, U.J.1
  • 38
    • 0021212919 scopus 로고
    • Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus
    • Armstrong, J., Niemann, H., Smeekens, S., Rottier, P. & Warren, G. Sequence and topology of a model intracellular membrane protein, E1 glycoprotein, from a coronavirus. Nature 308, 751-752 (1984).
    • (1984) Nature , vol.308 , pp. 751-752
    • Armstrong, J.1    Niemann, H.2    Smeekens, S.3    Rottier, P.4    Warren, G.5
  • 39
    • 70049096788 scopus 로고    scopus 로고
    • Structure and inhibition of the SARS coronavirus envelope protein ion channel
    • Pervushin, K. et al. Structure and inhibition of the SARS coronavirus envelope protein ion channel. PLoS Pathog. 5, e1000511 (2009).
    • (2009) PLoS Pathog. , vol.5 , pp. e1000511
    • Pervushin, K.1
  • 40
    • 77957006742 scopus 로고    scopus 로고
    • The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
    • Liu, J. et al. The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes. J. Infect. Dis. 202, 1171-1180 (2010).
    • (2010) J. Infect. Dis. , vol.202 , pp. 1171-1180
    • Liu, J.1
  • 41
    • 85005943436 scopus 로고    scopus 로고
    • T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
    • Liu, W. J. et al. T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV. Antivir. Res. 137, 82-92 (2017).
    • (2017) Antivir. Res. , vol.137 , pp. 82-92
    • Liu, W.J.1
  • 42
    • 84890049888 scopus 로고    scopus 로고
    • The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
    • Yang, Y. et al. The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists. Protein Cell 4, 951-961 (2013).
    • (2013) Protein Cell , vol.4 , pp. 951-961
    • Yang, Y.1
  • 43
    • 84897480727 scopus 로고    scopus 로고
    • Rapid generation of a mouse model for Middle East respiratory syndrome
    • Zhao, J. et al. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc. Natl Acad. Sci. USA 111, 4970-4975 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 4970-4975
    • Zhao, J.1


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