Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 40, 2017, Pages E8508-E8517

  Li, Wentao ^a   Hulswit, Ruben J G ^a   Widjaja, Ivy ^a   Raj, V Stalin ^b,g   McBride, Ryan ^c   Peng, Wenjie ^c   Widagdo, W ^b   Tortorici, M Alejandra ^d,e   Van Dieren, Brenda ^a   Lang, Yifei ^a   Van Lent, Jan W M ^f   Paulson, James C ^c   De Haan, Cornelis A M ^a   De Groot, Raoul J ^a   Van Kuppeveld, Frank J M ^a   Haagmans, Bart L ^b   Bosch, Berend Jan ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d INSTITUT PASTEUR   (France)

^e Institut Pasteur   (France)

^f WAGENINGEN UNIVERSITY   (Netherlands)

^g INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

Attachment; MERS CoV; Receptor; Sialic acid; Spike

Indexed keywords

CORONAVIRUS SPIKE GLYCOPROTEIN; DIPEPTIDYL PEPTIDASE IV; GLYCAN; MUCIN; SIALIC ACID; SIALIDASE; POLYSACCHARIDE; SIALIC ACID DERIVATIVE; VIRUS RECEPTOR;

ACETYLATION; AIRWAY EPITHELIUM CELL; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; AQUIFEX AEOLICUS; ARTICLE; BINDING AFFINITY; BINDING SITE; CALU-3 CELL LINE; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; DROMEDARY; ERYTHROCYTE; HEK293T CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; NONHUMAN; NOSE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING; TISSUE CULTURE; VIRAL TROPISM; VIRION; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS HEMAGGLUTINATION; ANIMAL; CAMEL; CORONAVIRUS INFECTION; GENETICS; METABOLISM; PATHOGENICITY; VIROLOGY;

ANIMALS; CAMELUS; CORONAVIRUS INFECTIONS; DIPEPTIDYL PEPTIDASE 4; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MUCINS; POLYSACCHARIDES; RECEPTORS, VIRUS; SIALIC ACIDS; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRUS ATTACHMENT;

EID: 85030211862     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1712592114     Document Type: Article

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