Amino Acid and Neurotransmitter Transporters

Comprehensive Molecular Insect Science

Volumn 5-6, Issue , 2005, Pages 255-307

  Boudko, D Y ^a   Donly, B C ^b   Stevens, B R ^a   Harvey, W R ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b AGRICULTURE AND AGRI FOOD CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85059600925     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B0-44-451924-6/00071-5     Document Type: Chapter

References (317)

1. Adams M.D., Celniker S.E., Holt R.A., et al. The genome sequence of Drosophila melanogaster. Science 2000, 287:2185-2195.
2. Agulhon C., Rostaing P., Ravassard P., Sagne C., Triller A., et al. Lysosomal amino acid transporter LYAAT-1 in the rat central nervous system: an in situ hybridization and immunohistochemical study. J. Comp. Neurol. 2003, 462:71-89.
3. Aihara Y., Mashima H., Onda H., Hisano S., Kasuya H., et al. Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter. J. Neurochem. 2000, 74:2622-2625.
4. Albritton L.M., Tseng L., Scadden D., Cunningham J.M. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus-infection. Cell 1989, 57:659-666.
5. Amara S.G., Fontana A.C. Excitatory amino acid transporters: keeping up with glutamate. Neurochem. Int. 2002, 41:313-318.
6. Amstutz M., Mohrmann M., Gmaj P., Murer H. Effect of pH on phosphate transport in rat renal brush border membrane vesicles. Am. J. Physiol. 1985, 248:F705-F710.
7. Arriza J.L., Eliasof S., Kavanaugh M.P., Amara S.G. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc. Natl Acad. Sci. USA 1997, 94:4155-4160.
8. Arriza J.L., Fairman W.A., Wadiche J.I., Murdoch G.H., Kavanaugh M.P., et al. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J. Neurosci. 1994, 14:5559-5569.
9. Arriza J.L., Kavanaugh M.P., Fairman W.A., Wu Y.N., Murdoch G.H., et al. Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family. J. Biol. Chem. 1993, 268:15329-15332.
10. Auger C., Attwell D. Fast removal of synaptic glutamate by postsynaptic transporters. Neuron 2000, 28:547-558.
11. + symporter in midgut brush-border membrane vesicles from larval Manduca sexta. J. Exp. Biol. 1995, 198:2599-2607.
12. Baier A., Wittek B., Brembs B. Drosophila as a new model organism for the neurobiology of aggression?. J. Exp. Biol. 2002, 205:1233-1240.
13. Bajmoczi M., Sneve M., Eide D.J., Drewes L.R. TATI encodes a low-affinity histidine transporter in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 1998, 243:205-209.
14. Balboni E. A proline shuttle in insect flight muscle. Biochem. Biophys. Res. Commun. 1978, 85:1090-1096.
15. Bassi M.T., Gasol E., Manzoni M., Pineda M., Riboni M., et al. Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system x(c) (-). Pflugers Archiv. 2001, 442:286-296.
16. Bellocchio E.E., Hu H., Pohorille A., Chan J., Pickel V.M., et al. The localization of the brain-specific inorganic phosphate transporter suggests a specific presynaptic role in glutamatergic transmission. J. Neurosci. 1998, 18:8648-8659.
17. Bellocchio E.E., Reimer R.J., Fremeau R.T., Edwards R.H. Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter. Science 2000, 289:957-960.
18. Bergersen L., Johannsson E., Veruki M.L., Nagelhus E.A., Halestrap A., et al. Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat. Neuroscience 1999, 90:319-331.
19. Bergersen L., Rafiki A., Ottersen O.P. Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system. Neurochem. Res. 2002, 27:89-96.
20. Bertran J., Werner A., Moore M.L., Stange G., Markovich D., et al. Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids. Proc. Natl Acad. Sci. USA 1992, 89:5601-5605.
21. Besson M.T., Soustelle L., Birman S. Identification and structural characterization of two genes encoding glutamate transporter homologues differently expressed in the nervous system of Drosophila melanogaster. FEBS Lett. 1999, 443:97-104.
22. Besson M.T., Soustelle L., Birman S. Selective high-affinity transport of aspartate by a Drosophila homologue of the excitatory amino-acid transporters. Curr. Biol. 2000, 10:207-210.
23. Beyenbach K.W. Energizing epithelial transport with the vacuolar H(+)-ATPase. News Physiol. Sci. 2001, 16:145-151.
24. Bicker G., Schafer S., Ottersen O.P., Storm-Mathisen J. Glutamate-like immunoreactivity in identified neuronal populations of insect nervous systems. J. Neurosci. 1988, 8:2108-2122.
25. Bismuth Y., Kavanaugh M.P., Kanner B.I. Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition. J. Biol. Chem. 1997, 272:16096-16102.
26. Boll M., Daniel H., Gasnier B. The SLC36 family: proton-coupled transporters for the absorption of selected amino acids from extracellular and intracellular proteolysis. Pflugers Arch. 2003, 2003 May 14 (Epub ahead of print).
27. Boll M., Foltz M., Rubio-Aliaga I., Daniel H. A cluster of proton/amino acid transporter genes in the human and mouse genomes. Genomics 2003, 82:47-56.
28. Boll M., Foltz M., Rubio-Aliaga I., Kottra G., Daniel H. Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters. J. Biol. Chem. 2002, 277:22966-22973.
29. Boll M., Herget M., Wagener M., Weber W.M., Markovich D., et al. Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter. Proc. Natl Acad. Sci. USA 1996, 93:284-289.
30. Boll M., Markovich D., Weber W.M., Korte H., Daniel H., et al. Expression cloning of a cDNA from rabbit small-intestine related to proton-coupled transport of peptides, beta-lactam antibiotics and Ace-inhibitors. Pflugers Arch. 1994, 429:146-149.
31. Bonen A. Lactate transporters (MCT proteins) in heart and skeletal muscles. Med. Sci. Sports Exercise 2000, 32:778-789.
32. Bossi E., Centinaio E., Castagna M., Giovannardi S., Vincenti S., et al. Ion binding and permeation through the lepidopteran amino acid transporter KAAT1 expressed in Xenopus oocytes. J. Physiol. -Lond. 1999, 515:729-742.
33. Bossi E., Sacchi V.F., Peres A. Ionic selectivity of the coupled and uncoupled currents carried by the amino acid transporter KAAT1. Pflugers Archiv. 1999, 438:788-796.
34. Boudko, D.Y., Kohn, A.B., Meleshkevitch, E.A., Dasher, M.K., Seron, T.J., et al., Ancestry and progency of nutrient amino acid transporters. Proc. Natl Acad. Sci. USA (in press).
35. Boudko D.Y., Moroz L.L., Harvey W.R., Linser P.J. Alkalinization by chloride/bicarbonate pathway in larval mosquito midgut. Proc. Natl Acad. Sci. USA 2001, 98:15354-15359.
36. Boudko D.Y., Moroz L.L., Linser P.J., Trimarchi J.R., Smith P.J., et al. In situ analysis of pH gradients in mosquito larvae using non-invasive, self-referencing, pH-sensitive microelectrodes. J. Exp. Biol. 2001, 204:691-699.
37. Breer H., Knipper M. Regulation of high affinity choline uptake. J. Neurobiol. 1990, 21:269-275.
38. Bridges C.C., Kekuda R., Wang H.P., Prasad P.D., Mehta P., et al. Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 2001, 42:47-54.
39. Broer A., Albers A., Setiawan I., Edwards R.H., Chaudhry F.A., et al. Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions. J. Physiol. -Lond. 2002, 539:3-14.
40. Broer A., Wagner C.A., Lang F., Broer S. The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. Biochem. J. 2000, 349:787-795.
41. Broer S., Broer A., Schneider H.P., Stegen C., Halestrap A.P., et al. Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem. J. 1999, 341:529-535.
42. Broer S., Schneider H.P., Broer A., Rahman B., Hamprecht B., et al. Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Biochem. J. 1998, 333:167-174.
43. Broer S., Schuster A., Wagner C.A., Broer A., Forster I., et al. Chloride conductance and Pi transport are separate functions induced by the expression of NaPi-1 in Xenopus oocytes. J. Membr. Biol. 1998, 164:71-77.
44. Brown C.S., Nestler C. Catecholamines and indolalkylamines. Comprehensive Insect Physiology, Biochemistry and Pharmacology 1985, vol. 11:436-497. Pergamon Press, Oxford. G.A. Kerkut, L.I. Gilbert (Eds.).
45. Busch A.E., Biber J., Murer H., Lang F. Electrophysiological insights of type I and II Na/Pi transporters. Kidney Int. 1996, 49:986-987.
46. Busch A.E., Schuster A., Waldegger S., Wagner C.A., Zempel G., et al. Expression of a renal type I sodium/phosphate transporter (NaPi-1) induces a conductance in Xenopus oocytes permeable for organic and inorganic anions. Proc. Natl Acad. Sci. USA 1996, 93:5347-5351.
47. Callec J.J. Synaptic transmission in the central nervous system. Comprehensive Insect Physiology, Biochemistry and Pharmacology 1985, vol. 5:139-179. Pergamon Press, Oxford. G.A. Kerkut, L.I. Gilbert (Eds.).
48. Carew T.J. Molecular enhancement of memory formation. Neuron 1996, 16:5-8.
49. Castagna M., Shayakul C., Trotti D., Sacchi V.F., Harvey W.R., et al. Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis. J. Exp. Biol. 1997, 200:269-286.
50. Castagna M., Shayakul C., Trotti D., Sacchi V.F., Harvey W.R., et al. Cloning and characterization of a potassium-coupled amino acid transporter. Proc. Natl Acad. Sci. USA 1998, 95:5395-5400.
51. Castagna M., Vincenti S., Marciani P., Sacchi V.F. Inhibition of the lepidopteran amino acid co-transporter KAAT1 by phenylglyoxal: role of arginine 76. Insect Mol. Biol. 2002, 11:283-289.
52. Caveney S., Donly B.C. Neurotransmitter transporters in the insect nervous system. Adv. Insect Physiol. 2002, 29:55-149.
53. Chaudhry F.A., Krizaj D., Larsson P., Reimer R.J., Wreden C., et al. Coupled and uncoupled proton movement by amino acid transport system N. EMBO J. 2001, 20:7041-7051.
54. Chen H., Pan Y.X., Wong E.A., Bloomquist J.R., Webb K.E. Molecular cloning and functional expression of a chicken intestinal peptide transporter (cPepT1) in Xenopus oocytes and Chinese hamster ovary cells. J. Nutr. 2002, 132:387-393.
55. Chen N.H., Reith M.E., Quick M.W. Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6. Pflugers Arch. 2003, 2003 Apr 29 (Epub ahead of print).
56. Chen P.S. Amino acid and protein metabolism in insect development. Adv. Insect Physiol. 1966, 3:53-132.
57. Chen Y., Swanson R.A. The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. J. Neurochem. 2003, 84:1332-1339.
58. Chen Z., Fei Y.J., Anderson C.M., Wake K.A., Miyauchi S., et al. Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2. J. Physiol. 2003, 546:349-361.
59. Chiang A.S., Lin W.Y., Liu H.P., Pszczolkowski M.A., Fu T.F., et al. Insect NMDA receptors mediate juvenile hormone biosynthesis. Proc. Natl Acad. Sci. USA 2002, 99:37-42.
60. +L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids. J. Biol. Chem. 1996, 271:17761-17770.
61. Chillaron J., Roca R., Valencia A., Zorzano A., Palacin M. Heteromeric amino acid transporters: biochemistry, genetics, and physiology. Am. J. Physiol. Renal Physiol. 2001, 281:F995-F1018.
62. Chiu C.-S., Ross L.S., Cohen B.N., Lester H.A., Gill S.S. The transporter-like protein inebriated mediates hyperosmotic stimuli through intracellular signalling. J. Exp. Biol. 2000, 203:3531-3546.
63. Christensen H.N. Transport system serving for mono-+ diamino acids. Proc. Natl Acad. Sci. USA 1964, 51:337-344.
64. Cioffi M., Wolfersberger M.G. Isolation of separate apical, lateral and basal plasma membrane from cells of an insect epithelium. A procedure based on tissue organization and ultrastructure. Tissue Cell 1983, 15:781-803.
65. Clark J.A., Amara S.G. Amino acid neurotransmitter transporters: structure, function, and molecular diversity. Bioessays 1993, 15:323-332.
66. Clements A.N. The Biology of Mosquitoes 1992, Chapman and Hall, London.
67. Closs E.I. Expression, regulation and function of carrier proteins for cationic amino acids. Curr. Opin. Nephrol. Hypertens. 2002, 11:99-107.
68. Cociancich S.O., Park S.S., Fidock D.A., Shahabuddin M. Vesicular ATPase-overexpressing cells determine the distribution of malaria parasite oocysts on the midguts of mosquitoes. J. Biol. Chem. 1999, 274:12650-12655.
69. Collett J.I. Small peptides, a life-long store of amino acid in adult Drosophila and Calliphora. J. Insect Physiol. 1976, 22:433-440.
70. Collins J.F., Bai L., Ghishan F.K. The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors. Pflugers Arch. 2003, May 21 (Epub ahead of print).
71. Copeland J., Robertson H.A. Octopamine as the transmitter at the firefly lantern - presence of an octopamine-sensitive and a dopamine-sensitive adenylate-cyclase. Comp. Biochem. Physiol. C -Pharmacol. Toxicol. Endocrinol. 1982, 72:125-127.
72. Corey J.L., Quick M.W., Davidson N., Lester H.A., Guastella J. A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization. Proc. Natl Acad. Sci. USA 1994, 91:1188-1192.
73. Danbolt N.C. Glutamate uptake. Prog. Neurobiol. 2001, 65:1-105.
74. Daniel H., Kottra G. The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflugers Arch. 2003, 2003 Aug 7 (Epub ahead of print).
75. Darboux I., Nielsen-LeRoux C., Charles J.F., Pauron D. The receptor of Bacillus sphaericus binary toxin in Culex pipiens (Diptera: Culicidae) midgut: molecular cloning and expression. Insect Biochem. Mol. Biol. 2001, 31:981-990.
76. Deken S.L., Fremeau R.T.J., Quick M.W. Family of sodium-coupled transporters for GABA, glycine, proline, betaine, taurine, and creatine. Neurotransmitter Transporters: Structure, Function and Regulation 2002, 193-234. Humana Press Inc., Totowa, New Jersey. M.E.A. Reith (Ed.).
77. Demchyshyn L.L., Pristupa Z.B., Sugamori K.S., Barker E.L., Blakely R.D., et al. Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster. Proc. Natl Acad. Sci. USA 1994, 91:5158-5162.
78. Deuticke B. Monocarboxylate transport in erythrocytes. J. Membr. Biol. 1982, 70:89-103.
79. Dimmer K.S., Friedrich B., Lang F., Deitmer J.W., Broer S. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem. J. 2000, 350:219-227.
80. +-dependent glutamate transporter. Eur. J. Biochem. 1997, 248:535-542.
81. Donly C., Jevnikar J., McLean H., Caveney S. Substrate-stereoselectivity of a high-affinity glutamate transporter cloned from the CNS of the cockroach Diploptera punctata. Insect Biochem. Mol. Biol. 2000, 30:369-376.
82. Drose S., Boddien C., Gassel M., Ingenhorst G., Zeeck A., et al. Semisynthetic derivatives of concanamycin A and C, as inhibitors of V- and P-type ATPases: structure-activity investigations and developments of photoaffinity probes. Biochemistry 2001, 40:2816-2825.
83. Eiden L.E., Schafer M.K., Weihe E., Schutz B. The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine. Pflugers Arch. 2003, 2003 May 6 (Epub ahead of print).
84. Erickson J.D., Eiden L.E., Hoffman B.J. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc. Natl Acad. Sci. USA 1992, 89:10993-10997.
85. Fairman W.A., Vandenberg R.J., Arriza J.L., Kavanaugh M.P., Amara S.G. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 1995, 375:599-603.
86. Farooqui T., Robinson K., Vaessin H., Smith B.H. Modulation of early olfactory processing by an octopaminergic reinforcement pathway in the honeybee. J. Neurosci. 2003, 23:5370-5380.
87. Fei Y.J., Kanai Y., Nussberger S., Ganapathy V., Leibach F.H., et al. Expression cloning of a mammalian proton-coupled oligopeptide transporter. Nature 1994, 368:563-566.
88. --independent. J. Biol. Chem. 2000, 275:24518-24526.
89. Fernandez E., Torrents D., Chillaron J., Martin Del Rio R., Zorzano A., et al. Basolateral LAT-2 has a major role in the transepithelial flux of L-cystine in the renal proximal tubule cell line OK. J. Am. Soc. Nephrol. 2003, 14:837-847.
90. Fernandez J., Bode B., Koromilas A., Diehl J.A., Krukovets I., et al. Translation mediated by the internal ribosome entry Site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner. J. Biol. Chem. 2002, 277:11780-11787.
91. Filippova M., Ross L.S., Gill S.S. Cloning of the v-ATPase B subunit from Culex Quinquefasciatus and expression of the B and C subunits in mosquitoes. Insect Mol. Biol. 1998, 7:223-232.
92. Fremeau R.T., Burman J., Qureshi T., Tran C.H., Proctor J., et al. The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate. Proc. Natl Acad. Sci. USA 2002, 99:14488-14493.
93. Fremeau R.T., Troyer M.D., Pahner I., Nygaard G.O., Tran C.H., et al. The expression of vesicular glutamate transporters defines two classes of excitatory synapse. Neuron 2001, 31:247-260.
94. Furuya S., Watanabe M. Novel neuroglial and glioglial relationships mediated by L-serine metabolism. Arch. Histol. Cytol. 2003, 66:109-121.
95. Gade G., Auerswald L. Beetles' choice - proline for energy output: control by AKHs. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 2002, 132:117-129.
96. Gainetdinov R.R., Caron M.G. Monoamine transporters. Neurotransmitter Transporters: Structure, Function and Regulation 2002, 171-192. Humana Press Inc., Totowa, New Jersey. M.E.A. Reith (Ed.).
97. Gallant P., Malutan T., McLean H., Verellen L., Caveney S., et al. Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth. Eur. J. Biochem. 2003, 270:664-674.
98. Gao X.J., McLean H., Caveney S., Donly C. Molecular cloning and functional characterization of a GABA transporter from the CNS of the cabbage looper, Trichoplusia ni. Insect Biochem. Mol. Biol. 1999, 29:609-623.
99. Garcia C.K., Brown M.S., Pathak R.K., Goldstein J.L. cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1. J. Biol. Chem. 1995, 270:1843-1849.
100. Garcia C.K., Li X., Luna J., Francke U. cDNA cloning of the human monocarboxylate transporter-1 and chromosomal localization of the Slc16a1 locus to 1p13.2-P12. Genomics 1994, 23:500-503.
101. Gardiner R.B., Ullensvang K., Danbolt N.C., Caveney S., Donly B.C. Cellular distribution of a high-affinity glutamate transporter in the nervous system of the cabbage looper Trichoplusia ni. J. Exp. Biol. 2002, 205:2605-2614.
102. Gasic G.P., Hollmann M. Molecular neurobiology of glutamate receptors. Annu. Rev. Physiol. 1992, 54:507-536.
103. Gasnier B. The SLC32 transporter, a key protein for the synaptic release of inhibitory amino acids. Pflugers Arch. 2003, 2003 May 16 (Epub ahead of print).
104. Gerencser G.A., Stevens B.R. Thermodynamics of symport and antiport catalyzed by cloned or native transporters. J. Exp. Biol. 1994, 196:59-75.
105. + symport in lepidopteran larval midgut. J. Exp. Biol. 1994, 196:145-155.
106. Giordana B., Sacchi V.F., Parenti P., Hanozet G.M. Amino acid transport systems in intestinal brush-border membranes from lepidopteran larvae. Am. J. Physiol. 1989, 257:R494-R500.
107. Gleason K.K., Dondeti V.R., Hsia H.L., Cochran E.R., Gumulak-Smith J., et al. The vesicular glutamate transporter 1 (xVGlut1) is expressed in discrete regions of the developing Xenopus laevis nervous system. Gene Expr. Patterns 2003, 3:503-507.
108. Graf P., Forstermann U., Closs E.I. The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C. Br. J. Pharmacol. 2001, 132:1193-1200.
109. Guastella J., Nelson N., Nelson H., Czyzyk L., Keynan S., et al. Cloning and expression of a rat brain GABA transporter. Science 1990, 249:1303-1306.
110. Halestrap A.P., Meredith D. The SLC16 gene family - from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch. 2003, Aug 28 (Epub ahead of print).
111. +-dependent phenylalanine uptake in membrane vesicles isolated from the midgut of Philosamia cynthia larvae. Biochim. Biophys. Acta. 1980, 596:481-486.
112. Harvey W.R. Physiology of V-ATPases. J. Exp. Biol. 1992, 172:1-17.
113. Harvey W.R., Cioffi M., Dow J.A., Wolfersberger M.G. Potassium ion transport ATPase in insect epithelia. J. Exp. Biol. 1983, 106:91-117.
114. Harvey W.R., Haskell J.A., Nedergaard S. Active transport by the Cecropia midgut. III. Midgut potential generated directly by active K-transport. J. Exp Biol. 1968, 48:1-12.
115. Harvey W.R., Haskell J.A., Zerahn K. Active transport of potassium and oxygen consumption in the isolated midgut of Hyalophora cecropia. J. Exp. Biol. 1967, 46:235-248.
116. + V-ATPases energize animal plasma membranes for secretion and absorption of ions and fluids. Am. Zool. 1998, 38:426-441.
117. Harvey W.R., Pung L., Meleshkevitch E.A., Kohn A., Boudko D.Y. Molecular and electrochemical integration of nutrient amino acid uptake in mosquito larvae 2003, Mt. Buller, Australia.
118. Hayashi M., Morimoto R., Yamamoto A., Moriyama Y. Expression and localization of vesicular glutamate transporters in pancreatic islets, upper gastrointestinal tract, and testis. J. Histochem. Cytochem. 2003, 51:1375-1390.
119. +-dependent inorganic phosphate cotransporter (DNPI) is a vesicular glutamate transporter in endocrine glutamatergic systems. J. Biol. Chem. 2001, 276:43400-43406.
120. Hemler M.E., Strominger J.L. Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines. J. Immunol. 1982, 129:623-628.
121. Hennigan B.B., Wolfersberger M.G., Harvey W.R. Neutral amino acid symport in larval Manduca sexta midgut brush-border membrane vesicles deduced from cation-dependent uptake of leucine, alanine, and phenylalanine. Biochim. Biophys. Acta 1993, 1148:216-222.
122. Hennigan B.B., Wolfersberger M.G., Parthasarathy R., Harvey W.R. Cation-dependent leucine, alanine, and phenylalanine uptake at pH 10 in brush-border membrane vesicles from larval Manduca sexta midgut. Biochim. Biophys. Acta 1993, 1148:209-215.
123. Holt R.A., Subramanian G.M., Halpern A., et al. The genome sequence of the malaria mosquito Anopheles gambiae. Science 2002, 298:129-149.
124. Homberg U. Neurotransmitters and neuropeptides in the brain of the locust. Microsc. Res. Tech. 2002, 56:189-209.
125. Huang X., Huang Y., Chinnappan R., Bocchini C., Gustin M.C., et al. The Drosophila inebriated-encoded neurotransmitter/osmolyte transporter: dual roles in the control of neuronal excitability and the osmotic stress response. Genetics 2002, 160:561-569.
126. Huang Y., Stern M. In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter. J. Neurosci. 2002, 22:1698-1708.
127. Huggett J.F., Mustafa A., O'Neal L., Mason D.J. The glutamate transporter GLAST-1 (EAAT-1) is expressed in the plasma membrane of osteocytes and is responsive to extracellular glutamate concentration. Biochem. Soc. Trans. 2002, 30:890-893.
128. Jackson V.N., Price N.T., Carpenter L., Halestrap A.P. Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation. Biochem. J. 1997, 324:447-453.
129. Jan L.Y., Jan Y.N. L-glutamate as an excitatory transmitter at the Drosophila larval neuromuscular junction. J. Physiol. 1976, 262:215-236.
130. Jan L.Y., Jan Y.N. Properties of the larval neuromuscular junction in Drosophila melanogaster. J. Physiol. 1976, 262:189-214.
131. Janecek S. Sequence similarities and evolutionary relationships of microbial, plant and animal alpha-amylases. Eur. J. Biochem. 1994, 224:519-524.
132. Jespersen T., Grunnet M., Angelo K., Klaerke D.A., Olesen S.P. Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes. Biotechniques 2002, 32:536-538. 540.
133. Jin X., Aimanova K., Ross L.S., Gill S.S. Identification, functional characterization and expression of a LAT type amino acid transporter from the mosquito Aedes aegypti. Insect Biochem. Mol. Biol. 2003, 33:815-827.
134. Johnson K., Knust E., Skaer H. bloated tubules (blot) encodes a Drosophila member of the neurotransmitter transporter family required for organisation of the apical cytocortex. Devel. Biol. 1999, 212:440-454.
135. Kanai Y., Hediger M.A. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 1992, 360:467-471.
136. Kanai Y., Smith C.P., Hediger M.A. The elusive transporters with a high affinity for glutamate. Trends Neurosci. 1993, 16:365-370.
137. Kanai Y., Trotti D., Berger U.V. The high-affinity glutamate and neutral amino-acid transporter family. Neurotransmitter Transporters: Structure, Function and Regulation 2002, 255-312. Humana Press Inc., Totowa, New Jersey. M.E.A. Reith (Ed.).
138. Kavanaugh M.P., Miller D.G., Zhang W., Law W., Kozak S.L., et al. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters. Proc. Natl Acad. Sci. USA 1994, 91:7071-7075.
139. Kekuda R., Prasad P.D., Fei Y.J., Torres-Zamorano V., Sinha S., et al. Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line. J. Biol. Chem. 1996, 271:18657-18661.
140. Kim do K., Kanai Y., Matsuo H., Kim J.Y., Chairoungdua A., et al. The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics 2002, 79:95-103.
141. Kim C.M., Goldstein J.L., Brown M.S. Cdna Cloning of Mev, a mutant protein that facilitates cellular uptake of mevalonate, and identification of the point mutation responsible for its gain of function. J. Biol. Chem. 1992, 267:23113-23121.
142. Kim D.K., Kanai Y., Chairoungdua A., Enomoto A., Inatomi J., et al. Identification and characterization of a novel epithelial aromatic amino acid transporter TAT1. Jap. J. Pharmacol. 2002, 88:223P.
143. +-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J. Biol. Chem. 2001, 276:17221-17228.
144. Kim J.W., Closs E.I., Albritton L.M., Cunningham J.M. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 1991, 352:725-728.
145. Kirk P., Wilson M.C., Heddle C., Brown M.H., Barclay A.N., et al. CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J. 2000, 19:3896-3904.
146. Kirschner M.A., Copeland N.G., Gilbert D.J., Jenkins N.A., Amara S.G. Mouse excitatory amino acid transporter EAAT2: isolation, characterization, and proximity to neuroexcitability loci on mouse chromosome 2. Genomics 1994, 24:218-224.
147. Kitamoto T., Wang W., Salvaterra P.M. Structure and organization of the Drosophila cholinergic locus. J. Biol. Chem. 1998, 273:2706-2713.
148. Kitamoto T., Xie X., Wu C.F., Salvaterra P.M. Isolation and characterization of mutants for the vesicular acetylcholine transporter gene in Drosophila melanogaster. J. Neurobiol. 2000, 42:161-171.
149. Kitamoto T., Xie X., Wu C.-F., Salvaterra P.M. Isolation and characterization of mutants for the vesicular acetylcholine transporter gene in Drosophila melanogaster. J. Neurobiol. 2000, 42:161-171.
150. Klemm N., Schneider L. Selective uptake of indolamine into nervous fibers in brain of desert locust, Schistocerca-Gregaria Forskal (Insecta) - fluorescence and electron-microscopic investigation. Comp. Biochem. Physiol. CPharmacol. Toxicol. Endocrinol. 1975, 50:177-182.
151. Knipper M., Strotmann J., Mädler U., Kahle C., Breer H. Monoclonal antibodies against the high affinity choline transport system. Neurochem. Int. 1989, 14:217-222.
152. Kostowski W., Tarchalska-Krynska B., Markowska L. Aggressive behavior and brain serotonin and catecholamines in ants (Formica rufa). Pharmacol. Biochem. Behav. 1975, 3:717-719.
153. Krantz D.E., Chaudhry F.A., Edwards R.H. Neurotransmitter transporters. Neurotransmitter Release 1999, 145-207. Oxford University Press, Oxford. H. Bellen (Ed.).
154. Kucharski R., Ball E.E., Hayward D.C., Maleszka R. Molecular cloning and expression analysis of a cDNA encoding a glutamate transporter in the honeybee brain. Gene 2000, 242:399-405.
155. Law J.H., Dunn P.E., Kramer K.J. Insect proteases and peptidases. Adv. Enzymol. Relat. Areas Mol. Biol. 1977, 45:389-425.
156. Leal S.M., Neckameyer W.S. Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster. J. Neurobiol. 2002, 50:245-261.
157. Leitch B., Judge S., Pitman R.M. Octopaminergic modulation of synaptic transmission between an identified sensory afferent and flight motorneuron in the locust. J. Comp. Neurol. 2003, 462:55-70.
158. Leonardi M.G., Casartelli M., Fiandra L., Parenti P., Giordana B. Role of specific activators of intestinal amino acid transport in Bombyx mori larval growth and nutrition. Arch. Insect Biochem. Physiol. 2001, 48:190-198.
159. Leonardi M.G., Fiandra L., Casartelli M., Cappellozza S., Giordana B. Modulation of leucine absorption in the larval midgut of Bombyx mori (Lepidoptera, Bombycidae). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 2001, 129:665-672.
160. Levi G., Raiteri M. Exchange of neurotransmitter amino-acid at nerve-endings can simulate high affinity uptake. Nature 1974, 250:735-737.
161. Li R., Younes M., Frolov A., Wheeler T.M., Scardino P., et al. Expression of neutral amino acid transporter ASCT2 in human prostate. Anticancer Res. 2003, 23:3413-3418.
162. +/peptide cotransporter. Cloning, functional expression, and chromosomal localization. J. Biol. Chem. 1995, 270:6456-6463.
163. - neurotransmitter transporters. Meth. Enzymol. 1998, 296:425-436.
164. Lin R.Y., Vera J.C., Chaganti R.S., Golde D.W. Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. J. Biol. Chem. 1998, 273:28959-28965.
165. Liu Q.R., Mandiyan S., Nelson H., Nelson N. A family of genes encoding neurotransmitter transporters. Proc. Natl Acad. Sci. USA 1992, 89:6639-6643.
166. + toxicity encodes a vesicular amine transporter. Cell 1992, 70:539-551.
167. + and zwitterionic lysine uptake by System B in brush border membrane vesicles from larval Manduca sexta midgut. Biochim. Biophys. Acta 1996, 1282:32-38.
168. +, in brush border membrane vesicles from larval Manduca sexta midgut. Biochim. Biophys. Acta 1996, 1282:25-31.
169. + amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity. J. Exp. Biol. 2003, 206:245-254.
170. MacGregor E.A., Janecek S., Svensson B. Relationship of sequence and structure to specificity in the alpha-amylase family of enzymes. Biochim. Biophys. Acta 2001, 1546:1-20.
171. Mackenzie B., Erickson J.D. Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflugers Arch. 2003, 2003 Jul 4 (Epub ahead of print).
172. Maddrell S.H. A diuretic hormone in Rhodnius Prolixus Stal. Nature 1962, 194:605-606.
173. Magagnin S., Werner A., Markovich D., Sorribas V., Stange G., et al. Expression cloning of human and rat renal cortex Na/Pi cotransport. Proc. Natl Acad. Sci. USA 1993, 90:5979-5983.
174. Maleszka R., Helliwell P., Kucharski R. Pharmacological interference with glutamate re-uptake impairs long-term memory in the honeybee, Apis mellifera. Behav. Brain Res. 2000, 115:49-53.
175. Malutan T., McLean H., Caveney S., Donly C. A high-affinity octopamine transporter cloned from the central nervous system of cabbage looper Trichoplusia ni. Insect Biochem. Mol. Biol. 2002, 32:343-357.
176. Mandel L.J., Moffett D.F., Riddle T.G., Grafton M.M. Coupling between oxidative metabolism and active transport in the midgut of tobacco hornworm. Am. J. Physiol. 1980, 238:C1-C9.
177. Manning Fox J.E., Meredith D., Halestrap A.P. Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J. Physiol. 2000, 529:285-293.
178. Marin M., Lavillette D., Kelly S.M., Kabat D. N-linked glycosylation and sequence changes in a critical negative control region of the ASCT1 and ASCT2 neutral amino acid transporters determine their retroviral receptor functions. J. Virol. 2003, 77:2936-2945.
179. Masson J., Sagne C., Hamon M., El Mestikawy S. Neurotransmitter transporters in the central nervous system. Pharmacol. Rev. 1999, 51:439-464.
180. Mastroberardino L., Spindler B., Pfeiffer R., Skelly P.J., Loffing J., et al. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family. Nature 1998, 395:288-291.
181. Mathews G.C., Diamond J.S. Neuronal glutamate uptake contributes to GABA synthesis and inhibitory synaptic strength. J. Neurosci. 2003, 23:2040-2048.
182. Matz M.V. Amplification of representative cDNA samples from microscopic amounts of invertebrate tissue to search for new genes. Methods Mol. Biol. 2002, 183:3-18.
183. Mbungu D., Ross L.S., Gill S.S. Cloning, functional expression, and pharmacology of a GABA transporter from Manduca sexta. Arch. Biochem. Biophys. 1995, 318:489-497.
184. McDonald T.J. Neuromuscular pharmacology of insects. Ann. Rev. Entomol. 1975, 20:151-166.
185. McIntire S.L., Jorgensen E., Horvitz H.R. Genes required for GABA function in Caenorhabditis elegans. Nature 1993, 364:334-337.
186. McIntire S.L., Reimer R.J., Schuske K., Edwards R.H., Jorgensen E.M. Identification and characterization of the vesicular GABA transporter. Nature 1997, 389:870-876.
187. Meier C., Ristic Z., Klauser S., Verrey F. Activation of system L heterodimeric amino acid exchangers by intracellular substrates. EMBO J. 2002, 21:580-589.
188. Meredith D., Bell P., McClure B., Wilkins R. Functional and molecular characterisation of lactic acid transport in bovine articular chondrocytes. Cell. Physiol. Biochem. 2002, 12:227-234.
189. Meredith D., Halestrap A.P. OX47 (basigin) may act as a chaperone for expression of the monocarboxylate transporter MCT1 at the plasma membrane of Xenopus laevis oocytes. J. Physiol. Lond. 2000, 526:23P-24P.
190. Miyamoto K., Tatsumi S., Sonoda T., Yamamoto H., Minami H., et al. Cloning and functional expression of a Na(+)-dependent phosphate co-transporter from human kidney: cDNA cloning and functional expression. Biochem. J. 1995, 305:81-85.
191. Monaghan D.T., Bridges R.J., Cotman C.W. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol. 1989, 29:365-402.
192. Monastirioti M. Biogenic amine systems in the fruit fly Drosophila melanogaster. Microsc. Res. Tech. 1999, 45:106-121.
193. Murer H., Forster I., Biber J. The sodium phosphate cotransporter family SLC34. Pflugers Arch. 2003, 16:16.
194. Murer H., Hernando N., Forster I., Biber J. Proximal tubular phosphate reabsorption: molecular mechanisms. Physiol. Rev. 2000, 80:1373-1409.
195. Muszynska-Pytel M., Cymboroski B. The role of serotonin in regulation of the circadian rhythm of locomotor activity in the cricket (Acheta domesticus L.) II. Distribution of serotonin and variations in different brain structure. Comp. Biochem. Physiol. C 1978, 59:17-20.
196. Muzynska-Pytel M., Cymborowski B. The role of serotonin in regulation of the circadian rhythms of locomotor activity in the cricket (Acheta domesticus L.) I. Circadian variations in serotonin concentration in the brain and hemolymph. Comp. Biochem. Physiol. C 1978, 59:13-15.
197. Nagaya Y., Kutsukake M., Chigusa S.I., Komatsu A. A trace amine, tyramine, functions as a neuromodulator in Drosophila melanogaster. Neurosci. Lett. 2002, 329:324-328.
198. Nathanson J.A., Hunnicutt E.J., Kantham L., Scavone C. Cocaine as a naturally occurring insecticide. Proc. Natl Acad. Sci. USA 1993, 90:9645-9648.
199. Neckameyer W.S. Dopamine and mushroom bodies in Drosophila: experience-dependent and-independent aspects of sexual behavior. Learn. Mem. 1998, 5:157-165.
200. Nedergaard S. Active transport of alpha-aminoisobutyric acid by the isolated midgut of Hyalophora cecropia. J. Exp. Biol. 1972, 56:167-172.
201. Nelson N., Lill H. Porters and neurotransmitter transporters. J. Exp. Biol. 1994, 196:213-228.
202. Nelson N., Sacher A., Nelson H. The significance of molecular slips in transport systems. Nat. Rev. Mol. Cell. Biol. 2002, 3:876-881.
203. Ni B., Rosteck P.R., Nadi N.S., Paul S.M. Cloning and expression of a cDNA encoding a brain-specific Na(+)-dependent inorganic phosphate cotransporter. Proc. Natl Acad. Sci. USA 1994, 91:5607-5611.
204. Nielsen-LeRoux C., Charles J.-F. Binding of Bacillus sphaericus binary toxin to a specific receptor on midgut brush-border membranes from mosquito larvae. Eur. J. Biochem. 1992, 210:585-590.
205. Novak M.G., Rowley W.A. Serotonin depletion affects blood-feeding but not host-seeking ability in Aedes triseriatus (Diptera: Culicidae). J. Med. Entomol. 1994, 31:600-606.
206. O'Donnell M.J., Maddrell S.H. Secretion by the Malpighian tubules of Rhodnius prolixus stal: electrical events. J. Exp. Biol. 1984, 110:275-290.
207. Okuda T., Haga T. Functional characterization of the human high-affinity choline transporter. FEBS Lett. 2000, 484:92-97.
208. Olah Z., Lehel C., Anderson W.B., Eiden M.V., Wilson C.A. The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter. J. Biol. Chem. 1994, 269:25426-25431.
209. Osborne R.H. Insect neurotransmission: neurotransmitters and their receptors. Pharmacol. Ther. 1996, 69:117-142.
210. Otis T.S., Wu Y.C., Trussell L.O. Delayed clearance of transmitter and the role of glutamate transporters at synapses with multiple release sites. J. Neurosci. 1996, 16:1634-1644.
211. Pacholczyk T., Blakely R.D., Amara S.D. Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 1991, 350:350-354.
212. Page R.D. TreeView: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 1996, 12:357-358.
213. Palacin M., Estevez R., Bertran J., Zorzano A. Molecular biology of mammalian plasma membrane amino acid transporters. Physiol. Rev. 1998, 78:969-1054.
214. Palacin M., Kanai Y. The ancillary proteins of HATs: SLC3 family of amino acid transporters. Pflugers Arch. 2003, 2003 Jun 11 (Epub ahead of print).
215. +-leucine symport of Bombyx mori larval midgut. Insect Biochem. Mol. Biol. 2000, 30:243-252.
216. Parenti P., Villa M., Hanozet G.M. Kinetics of leucine transport in brush border membrane vesicles from lepidopteran larvae midgut. J. Biol. Chem. 1992, 267:15391-15397.
217. Parsons S.M. Transport mechanisms in acetylcholine and monoamine storage. FASEB J. 2000, 14:2423-2434.
218. Patrick M.L., Bradley T.J. The physiology of salinity tolerance in larvae of two species of Culex mosquitoes: the role of compatible solutes. J. Exp. Biol. 2000, 203:821-830.
219. Paulsen I.T., Skurray R.A. Topology, structure and evolution of 2 families of proteins involved in antibiotic and antiseptic resistance in Eukaryotes and Prokaryotes - an analysis. Gene 1993, 124:1-11.
220. Pennetta G., Wu M., Bellen H.J. Dissecting the molecular mechanisms of neurotransmitter release in Drosophila. Neurotransmitter Release 1999, 304-351. Oxford University Press, Oxford. H. Bellen (Ed.).
221. Peres A., Bossi E. Effects of pH on the uncoupled, coupled and pre-steady-state currents at the amino acid transporter KAAT1 expressed in Xenopus oocytes. J. Physiol. Lond. 2000, 525:83-89.
222. Petersen S.A., Fetter R.D., Noordermeer J.N., Goodman C.S., DiAntonio A. Genetic analysis of glutamate receptors in Drosophila reveals a retrograde signal regulating presynaptic transmitter release. Neuron 1997, 19:1237-1248.
223. Pfeiffer R., Rossier G., Spindler B., Meier C., Kuhn L., et al. Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family. EMBO J. 1999, 18:49-57.
224. Pfeiffer R., Spindler B., Loffing J., Skelly P.J., Shoemaker C.B., et al. Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond. FEBS Lett. 1998, 439:157-162.
225. Philp N.J., Yoon H.Y., Lombardi L. Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia. Am. J. Physiol. -Cell Physiol. 2001, 280:C1319-C1326.
226. + transporter isoforms MCT1 and MCT4 in human skeletal muscle. Am. J. Physiol. 1999, 276:E843-E848.
227. Porzgen P., Park S.K., Hirsh J., Sonders M.S., Amara S.G. The antidepressant-sensitive dopamine transporter in Drosophila melanogaster: a primordial carrier for catecholamines. Mol. Pharmacol. 2001, 59:83-95.
228. Price N.T., Jackson V.N., Halestrap A.P. Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past. Biochem. J. 1998, 329:321-328.
229. Quick M., Stevens B.R. Amino acid transporter CAATCH1 is also an amino acid-gated cation channel. J. Biol. Chem. 2001, 276:33413-33418.
230. Rand J.B., Duerr J.S., Frisby D.L. Neurogenetics of vesicular transporters in C. elegans. FASEB J. 2000, 14:2414-2422.
231. Rasko J.E.J., Battini J.-L., Gottschalk R.J., Mazo I., Miller A.D. The RD114/simian type D retrovirus receptor is a neutral amino acid transporter. Proc. Natl Acad. Sci. USA 1999, 96:2129-2134.
232. Reimer R.J., Edwards R.H. Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Pflugers Arch. 2003, 2003 Jun 17 (Epub ahead of print).
233. Reuveni M., Dunn P.E. Proline transport into brush border membrane vesicles from the midgut of Manduca sexta larvae. Comp. Biochem. Physiol. Comp. Physiol. 1994, 107:685-691.
234. +-dependent high-affinity glutamate transport in macrophages. J. Immunol. 2000, 164:5430-5438.
235. Robertson H.A., Carlson A.D. Octopamine - presence in firefly lantern suggests a transmitter role. J. Exp. Zool. 1976, 195:159-164.
236. Roeder T. Octopamine in invertebrates. Progr. Neurobiol. 1999, 59:533-561.
237. Roman G., Meller V., Wu K.H., Davis R.L. The opt1 gene of Drosophila melanogaster encodes a proton-dependent dipeptide transporter. Am. J. Physiol. Cell Physiol. 1998, 44:C857-C869.
238. Rossier G., Meier C., Bauch C., Summa V., Sordat B., et al. LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine. J. Biol. Chem. 1999, 274:34948-34954.
239. Rost B. PHD: predicting one-dimensional protein structure by profile-based neural networks. Methods Enzymol. 1996, 266:525-539.
240. Rothstein J.D., Dykes-Hoberg M., Pardo C.A., Bristol L.A., Jin L., et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 1996, 16:675-686.
241. Rubio-Aliaga I., Boll M., Daniel H. Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2. Biochem. Biophys. Res. Commun. 2000, 276:734-741.
242. Sacchi V.F., Castagna M., Mari S.A., Perego C., Bossi E., et al. Glutamate 59 is critical for transport function of the amino acid cotransporter KAAT1. Am. J. Physiol. Cell Physiol. 2003, 285:C623-C632.
243. Sagne C., Agulhon C., Ravassard P., Darmon M., Hamon M., et al. Identification and characterization of a lysosomal transporter for small neutral amino acids. Proc. Natl Acad. Sci. USA 2001, 98:7206-7211.
244. Sagne C., El Mestikawy S., Isambert M.F., Hamon M., Henry J.P., et al. Cloning of a functional vesicular GABA and glycine transporter by screening of genome databases. FEBS Lett. 1997, 417:177-183.
245. Saier M.H. Vectorial metabolism and the evolution of transport systems. J. Bacteriol. 2000, 182:5029-5035.
246. Saier M.H. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol. Mol. Biol. Rev. 2000, 64:354-411.
247. Saito H., Terada T., Okuda M., Sasaki S., Inui K. Molecular cloning and tissue distribution of rat peptide transporter PEPT2. Biochim. Biophys. ActaBiomembr. 1996, 1280:173-177.
248. Saitou N., Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 1987, 4:406-425.
249. Sakata K., Yamashita T., Maeda M., Moriyama Y., Shimada S., et al. Cloning of a lymphatic peptide/histidine transporter. Biochem. J. 2001, 356:53-60.
250. Sandhu S.K., Ross L.S., Gill S.S. Molecular cloning and functional expression of a proline transporter from Manduca sexta. Insect Biochem. Mol. Biol. 2002, 32:1391-1400.
251. Sandhu S.K., Ross L.S., Gill S.S. A cocaine insensitive chimeric insect serotonin transporter reveals domains critical for cocaine interaction. Eur. J. Biochem. 2002, 269:3934-3944.
252. Sato H., Tamba M., Ishii T., Bannai S. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. J. Biol. Chem. 1999, 274:11455-11458.
253. Sato H., Tamba M., Okuno S., Sato K., Keino-Masu K., et al. Distribution of cystine/glutamate exchange transporter, system x(c) (-), in the mouse brain. J. Neurosci. 2002, 22:8028-8033.
254. Schneider M., Rudin W., Hecker H. Absorption and transport of radioactive-tracers in the midgut of the malaria mosquito, Anopheles-Stephensi. J. Ultrastruct. Mol. Struct. Res. 1986, 97:50-63.
255. Schuldiner S., Shirvan A., Linial M. Vesicular neurotransmitter transporters: from bacteria to humans. Physiol. Rev. 1995, 75:369-392.
256. Schuldiner S., Shirvan A., Stern-Bach Y., Steiner-Mordoch S., Yelin R., et al. From bacterial antibiotic resistance to neurotransmitter uptake. A common theme of cell survival. Ann. N. Y. Acad. Sci. 1994, 733:174-184.
257. Schulz D.J., Barron A.B., Robinson G.E. A role for octopamine in honey bee division of labor. Brain Behav. Evol. 2002, 60:350-359.
258. Schuster C.M., Ultsch A., Schloss P., Cox J.A., Schmitt B., et al. Molecular cloning of an invertebrate glutamate receptor subunit expression in Drosophila muscle. Science 1991, 254:112-114.
259. Seal R.P., Amara S. Excitatory amino acid transporters: a family in flux. Annu. Rev. Pharmacol. Toxicol. 1999, 39:431-456.
260. Seal R.P., Daniels G.M., Wolfgang W.J., Forte M., Amara S. Identification and characterization of a cDNA encoding a neuronal glutamate transporter from Drosophila melanogaster. Recept. Channels 1998, 6:51-64.
261. Simell O. Lysinuric protein intolerance and other cationic amino acidurias. Metabolic and Molecular Bases of Inherited Diseases 2001, 4933-4956. McGraw-Hill, New York. C.R. Scriver, S.W. Beaudet (Eds.).
262. Sinakevitch I.G., Geffard M., Pelhate M., Lapied B. Octopamine-like immunoreactivity in the dorsal unpaired median (Dum) neurons innervating the accessory-gland of the male cockroach Periplaneta-Americana. Cell Tiss. Res. 1994, 276:15-21.
263. +. J. Biol. Chem. 1999, 274:23740-23745.
264. Soehnge H., Huang X., Becker M., Whitley P., Conover D., et al. A neurotransmitter transporter encoded by the Drosophila inebriated gene. Proc. Natl Acad. Sci. USA 1996, 93:13262-13267.
265. Spivak M., Masterman R., Ross R., Mesce K.A. Hygienic behavior in the honey bee (Apis mellifera L.) and the modulatory role of octopamine. J. Neurobiol. 2003, 55:341-354.
266. Steiner H.Y., Naider F., Becker J.M. The PTR family: a new group of peptide transporters. Mol. Microbiol. 1995, 16:825-834.
267. Stern M., Ganetzky B. Identification and characterization of inebriated, a gene affecting neuronal excitability in Drosophila. J. Neurogenet. 1992, 8:157-172.
268. Stevens B.R., Feldman D.H., Liu Z., Harvey W.R. Conserved tyrosine-147 plays a critical role in the ligand-gated current of the epithelial cation/amino acid transporter/channel CAATCH1. J. Exp. Biol. 2002, 205:2545-2553.
269. Stuart A.E. From fruit flies to barnacles, histamine is the neurotransmitter of arthropod photoreceptors. Neuron 1999, 22:431-433.
270. Suchak S.K., Baloyianni N.V., Perkinton M.S., Williams R.J., Meldrum B.S., et al. The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. J. Neurochem. 2003, 84:522-532.
271. Tabb J.S., Ueda T. Phylogenetic studies on the synaptic vesicle glutamate transport system. J. Neurosci. 1991, 11:1822-1828.
272. Takamori S., Rhee J.S., Rosenmund C., Jahn R. Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2). J. Neurosci. 2001, 21:RC182.
273. Tate S.S., Yan N., Udenfriend S. Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney. Proc. Natl Acad. Sci. USA 1992, 89:1-5.
274. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997, 25:4876-4882.
275. Tomi M., Funaki T., Abukawa H., Katayama K., Kondo T., et al. Expression and regulation of L-cystine transporter, system x(c) (-), in the newly developed rat retinal Muller cell line (TR-MUL). Glia 2003, 43:208-217.
276. +/dipeptide cotransporter and distribution of the transport activity in isolated rabbit intestinal epithelial cells. J. Pharmacol. Exp. Ther. 1995, 272:63-69.
277. Torres G.E., Gainetdinov R.R., Caron M.G. Plasma membrane monoamine transporters: structure, regulation and function. Nat. Rev. Neurosci. 2003, 4:13-25.
278. Toure A., Morin L., Pineau C., Becq F., Dorseuil O., et al. Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to RhoGTPase signaling. J. Biol. Chem. 2001, 276:20309-20315.
279. Umesh A., Cohen B.N., Ross L.S., Gill S.S. Functional characterization of a glutamate/aspartate transporter from the mosquito Aedes aegypti. J. Exp. Biol. 2003, 206:2241-2255.
280. Umesh A., Gill S.S. Immunocytochemical localization of a Manduca sexta gamma-aminobutyric acid transporter. J. Comp. Neurol. 2002, 448:388-398.
281. Usherwood P.N.R. Insect glutamate receptors. Adv. Insect. Physiol. 1994, 24:309-341.
282. +-dependent neutral amino acid transporter. J. Biol. Chem. 1996, 271:14883-14890.
283. +/P-I transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses. J. Neurosci. 2002, 22:142-155.
284. +/PI transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses. J. Neurosci. 2002, 22:142-155.
285. Verrey F., Closs E.I., Wagner C.A., Palacin M., Endou H., Kanai Y. CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch. 2003, 2003. Jun 11 (Epub ahead of print).
286. Verri T., Kottra G., Romano A., Tiso N., Peric M., et al. Molecular and functional characterisation of the zebrafish (Danio rerio) PEPT1-type peptide transporter. FEBS Lett. 2003, 549:115-122.
287. Vincenti S., Castagna M., Peres A., Sacchi V.F. Substrate selectivity and pH dependence of KAAT1 expressed in Xenopus laevis oocytes. J. Membr. Biol. 2000, 174:213-224.
288. Vincourt J.B., Jullien D., Amalric F., Girard J.P. Molecular and functional characterization of SLC26A11, a sodium-independent sulfate transporter from high endothelial venules. FASEB J. 2003, 17:890-892.
289. Wang H.Y., Tamba M., Kimata M., Sakamoto K., Bannai S., et al. Expression of the activity of cystine/glutamate exchange transporter, system x(c) (-), by xCT and rBAT. Biochem. Biophys. Res. Commun. 2003, 305:611-618.
290. Watanabe K., Hata Y., Kizaki H., Katsube Y., Suzuki Y. The refined crystal structure of Bacillus cereus oligo-1,6-glucosidase at 2.0 angstrom resolution: structural characterization of proline-substitution sites for protein thermostabilization. J. Mol. Biol. 1997, 269:142-153.
291. Watson A.H.D., Schurmann F.-W. Synaptic structure, distribution, and circuitry in the central nervous system of the locust and related insects. Microsc. Res. Tech. 2002, 56:210-226.
292. Wells R.G., Hediger M.A. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases. Proc. Natl Acad. Sci. USA 1992, 89:5596-5600.
293. Werner A., Moore M.L., Mantei N., Biber J., Semenza G., et al. Cloning and expression of cDNA for a Na/Pi cotransport system of kidney cortex. Proc. Natl Acad. Sci. USA 1991, 88:9608-9612.
294. Wieczorek H., Brown D., Grinstein S., Ehrenfeld J., Harvey W.R. Animal plasma membrane energization by proton-motive V-ATPases. Bioessays 1999, 21:637-648.
295. +-V-ATPase from tobacco hornworm midgut. J. Bioenerg. Biomembr. 1999, 31:67-74.
296. + antiport in an animal plasma membrane. J. Biol. Chem. 1991, 266:15340-15347.
297. Wieczorek H., Weerth S., Schindlbeck M., Klein U. A vacuolar-type proton pump in a vesicle fraction enriched with potassium transporting plasma membranes from tobacco hornworm midgut. J. Biol. Chem. 1989, 264:11143-11148.
298. Wilson M.C., Jackson V.N., Heddle C., Price N.T., Pilegaard H., et al. Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3. J. Biol. Chem. 1998, 273:15920-15926.
299. Wilson M.C., Meredith D., Halestrap A.P. Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ. J. Biol. Chem. 2002, 277:3666-3672.
300. Wipf D., Ludewig U., Tegeder M., Rentsch D., Koch W., et al. Conservation of amino acid transporters in fungi, plants and animals. Trends Biochem. Sci. 2002, 27:139-147.
301. Witte I., Kreienkamp H.-J., Gewecke M., Roeder T. Putative histamine-gated chloride channel subunits of the insect visual system and thoracic ganglion. J. Neurochem. 2002, 83:504-514.
302. Wolf S., Janzen A., Vekony N., Martine U., Strand D., et al. Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. Biochem. J. 2002, 364:767-775.
303. Wolfersberger M.G. Amino acid transport in insects. Annu. Rev. Entomol. 2000, 45:111-120.
304. Wolfgang C.L., Lin C., Meng Q., Karinch A.M., Vary T.C., et al. Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases. J. Gastrointest. Surg. 2003, 7:149-156.
305. Xie T., Parthasarathy R., Wolfersberger M.G., Harvey W.R. Anomalous glutamate/alkali cation symport in larval Manduca sexta midgut. J. Exp. Biol. 1994, 194:181-194.
306. Yamashita T., Shimada S., Guo W., Sato K., Kohmura E., et al. Cloning and functional expression of a brain peptide/histidine transporter. J. Biol. Chem. 1997, 272:10205-10211.
307. Yasuyama K., Meinertzhagen I.A., Schurmann F.W. Synaptic organization of the mushroom body calyx in Drosophila melanogaster. J. Comp. Neurol. 2002, 445:211-226.
308. Yelin R., Schuldiner S. The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters. FEBS Lett. 1995, 377:201-207.
309. Yelin R., Schuldiner S. Vesicular neurotransmitter transporters. Neurotransmitter Transporters: Structure, Function and Regulation 2002, 313-355. Humana Press Inc., Totowa, New Jersey. M.E.A. Reith (Ed.).
310. Yellman C., Tao H., He B., Hirsh J. Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila. Proc. Natl Acad. Sci. USA 1997, 94:4131-4136.
311. Yoon H.Y., Fanelli A., Grollman E.F., Philp N.J. Identification of a unique monocarboxylate transporter (MCT3) in retinal pigment epithelium. Biochem. Biophys. Res. Commun. 1997, 234:90-94.
312. Young G.B., Jack D.L., Smith D.W., Saier M.H. The amino acid/auxin:proton symport permease family. Biochim. Biophys. Acta 1999, 1415:306-322.
313. Zhao C., Wilson M.C., Schuit F., Halestrap A.P., Rutter G.A. Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas. Diabetes 2001, 50:361-366.
314. Zharikov S.I., Sigova A.A., Chen S., Bubb M.R., Block E.R. Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001, 280:L465-L473.
315. Zhuang Z., Linser P.J., Harvey W.R. Antibody to H(+) V-ATPase subunit E colocalizes with portasomes in alkaline larval midgut of a freshwater mosquito (Aedes aegypti). J. Exp. Biol. 1999, 202:2449-2460.
316. - Proteome Bio Tuat. http://sosui.proteome.bio.tuat.ac.jp.
317. - NCBI. http://www.ncbi.nlm.nih.gov.