K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity

Journal of Experimental Biology

Volumn 206, Issue 2, 2003, Pages 245-254

  Liu, Zhilin ^a,c   Stevens, Bruce R ^b   Feldman, Daniel H ^b,d   Hediger, Matthias A ^c   Harvey, William R ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d SHRINERS HOSPITALS FOR CHILDREN NORTHERN CALIFORNIA   (United States)

Author keywords

Amino acid; CAATCH1; GAT1; KAAT1; Leakage current; Potassium; Sodium; Transporter

Indexed keywords

AMINO ACID; AMINO ACID TRANSPORTER; CARRIER PROTEIN; INSECT PROTEIN; KAAT1 PROTEIN, INSECT; LEUCINE; LITHIUM; MEMBRANE PROTEIN; POTASSIUM; RECOMBINANT PROTEIN; SODIUM;

ACTIVE TRANSPORT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; DRUG EFFECT; FEMALE; GENETICS; IN VITRO STUDY; KINETICS; LEPIDOPTERA; METABOLISM; MOLECULAR GENETICS; OOCYTE; POINT MUTATION; PROTEIN SECONDARY STRUCTURE; XENOPUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; AMINO ACIDS; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CARRIER PROTEINS; FEMALE; INSECT PROTEINS; KINETICS; LEUCINE; LITHIUM; MANDUCA; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; OOCYTES; POINT MUTATION; POTASSIUM; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SODIUM; XENOPUS;

ANIMALIA; INSECTA; LEPIDOPTERA;

EID: 0347787053     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.00065     Document Type: Article

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