Proximal tubular phosphate reabsorption: Molecular mechanisms

Physiological Reviews

Volumn 80, Issue 4, 2000, Pages 1373-1409

  Murer, Heini ^a   Hernando, Nati ^a   Forster, Ian ^a   Biber, Jürg ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; ATRIAL NATRIURETIC FACTOR; CALCITONIN; CARRIER PROTEIN; DIURETIC AGENT; GLUCAGON; GLUCOCORTICOID; GROWTH FACTOR; GROWTH HORMONE; HYPOCALCIN; INSULIN; LIPID; PARATHYROID HORMONE; PHOSPHATE; PROSTAGLANDIN; SODIUM; SOMATOMEDIN; THYROID HORMONE; VITAMIN D;

ACID BASE BALANCE; AGING; BRUSH BORDER; CALCIUM BLOOD LEVEL; DIABETES MELLITUS; DIET RESTRICTION; DIETARY INTAKE; DISULFIDE BOND; DIURETIC THERAPY; ELECTROPHYSIOLOGY; GENE EXPRESSION; GENE EXPRESSION SYSTEM; GENETICS; HUMAN; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE ABSORPTION; MODEL; MOLECULAR BIOLOGY; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; ONTOGENY; PHOSPHATE TRANSPORT; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SODIUM TRANSPORT; TISSUE CULTURE; TRANSPORT KINETICS; X CHROMOSOME LINKED DISORDER;

EID: 0033775213     PISSN: 00319333     EISSN: None     Source Type: Journal    
DOI: 10.1152/physrev.2000.80.4.1373     Document Type: Review

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299. Cross-transplantation of kidneys in normal and Hyp mice: Evidence that the hyp phenotype is unrelated to an intrinsic renal defect
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301. Cloning and expression of a cDNA encoding a brain-specific Na-dependent inorganic phosphate cotransporter
302. Stimulation by thyroid hormone of phosphate transport in primary cultured renal cells
303. Inhibition by glucocorticoids of phosphate transport in primary cultured renal cells
304. In vivo suppression of the renal Na/P(i) cotransporter by antisense oligonucleotides
305. Influence of calcium and ionophore 23187 on tubular phosphate reabsorption
306. The cellular receptor for gibbon ape leukemia virus is a novel high affinity sodium-dependent phosphate transporter
307. Expression of a newly identified phosphate transporter/retrovirus receptor in human SaOS-2 osteoblast-like cells and its regulation by insulin-like growth factor I
308. Na/p(i) cotransport alters rapidly cytoskeletal protein polymerization dynamics in oppossum kidney cells
309. Membrane topography of the renal phosphate carrier NaPi-2: Limited proteolysis studies
310. Parathyroid hormone inhibits plasma membrane P(i) transport without changing endocytic activity in opossum kidney cells
311. Inhibition of phosphatidylinositide 3-kinase reduces in OK cells Na/P(i) cotransport but does not interfere with its regulation by PTH
312. +/P(i) cotransporters by PTH
313. Cellular mechanisms involved in the acute adaptation of NA/P(i) cotransport to high or low-P(i) medium in OK cells
314. Parathyroid hormone-dependent degradation of type II Na/P(i) cotransporters
315. Lysosomal degradation of renal type II Ns/P(i) cotransporter, a novel principle in the regulation of membrane transport
316. Effect of renal interstitial adenosine infusion on phosphate excretion in diabtes mellitus rats
317. Inhibitory effects of volume expansion performed in vivo on transport of the isolated rabbit proximal tubule perfused in vitro
318. Effect of transforming growth factor-α and parathyroid hormone-related protein on phosphate transport in renal cells
319. Effect of synthetic tumoral PTH-related peptide on cAMP production and Na-dependent P(i) transport
320. Dietary intake of phosphorus modulates the circadian rhythm in serum concentration of phosphorus
321. Influence of extracellular fluid volume expansion on magnesium calcium and phosphate handling along the rat nephron
322. Phosphate reabsorption in rat nephron terminal segments: Intrarenal heterogeneity and strain differences
323. Phosphate uptake by proximal cells isolated from rabbit kidney: Role of dexamethasone
324. Effect of glucocorticoids on neonatal rabbit renal cortical sodium-inorganic phosphate messenger RNA and protein abundance
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327. Brush-border membrane phosphate transport: Effects of volume expansion
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343. Functional asymmetry of phosphate transport and its regulation in OK cells: Phosphate transport
344. Functional asymmetry in phosphate transport and its regulation in OK cells: Parathyroid hormone inhibition
345. Apical and basolateral effects of PTH in OK cells: Transport inhibition, messenger production, effects of pertussis toxin and interaction with a PTH-analog
346. Involvement of C3 exotoxin-sensitive G proteins (rho/rac) in PTH signal transduction in OK cells
347. Parathyrod hormone regulation in OK cells: In situ protein phosphorylation reactions involving PKA, PKC and GTP-binding proteins
348. Parathyroid hormone induced alterations of protein content and phosphorylation in enriched membranes of opossum kidney cells
349. Parathyroid hormone inhibits proximal tubule Na-K-ATPase activity
350. 2+/polyvalent cation-sensing protein in rat kidney
351. +/P(i) cotransporter mRNA in rat kidney
352. Tumoral parathyroid hormone-related protein: A new hormone affecting calcium and phosphate transport
353. Growth hormone activates phospholipase C in proximal tubular basolateral membranes from canine kidney
354. Modulation of phosphate absorption by calcium in the rabbit proximal convoluted tubule
355. Sodium gradient-dependent phosphate transport in renal brush-border membrane vesicles: Effect of an intravesicular greater than extravesicular proton gradient
356. The role of cytosolic calcium in chronic adaptation to phosphate depletion in opossum kidney cells
357. Adaptation to phosphate depletion in opossum kidney cells
358. Electrogenic Na-independent P(i) transport in canine renal basolateral membrane vesicles
359. Na-gradient dependent P(i) uptake in basolateral membrane vesicles from dog kidney
360. Transfection-mediated expression of a dominant cAMP-resistant phenotype in the opossum kidney (OK) cell line prevents parathyroid hormone-induced inhibition of Na-phosphate cotransport
361. Renal endosomal phosphate (P(i)) transport in normal and diabetic rats and response to chronic P(i) deprivation
362. The role of AP2 consensus sites in the regulation of the rat Npt2 (sodium-phosphate cotransporter) promoter
363. Renal adaptation to a low phosphate diet in rats. Blockade by actinomycin D
364. Parathyroid hormone stimulates ecto-5'-nucleotidase activity in renal epithelial cells: Role of protein kinase C
365. Expression of the PiT transporter in the kidney
366. A putative growth-related Na-P(i) cotransporter
367. Mechanism of renal phosphate retention during growth
368. Cellular mechanisms of the age-related decrease in renal phosphate reabsorption
369. Cloning of a Na/P(i) cotransporter from opossum kidney cells
370. Thyroid hormone stimulation of Na/P(i) cotransport in opossum kidney cells
371. + channel (EnaC) by ubiquitination
372. Regulation of ion transport by protein-protein interaction domains
373. Effect of dietary phosphate intake on phosphate transport by isolated rat renal brush-border vesicles
374. 3
375. Effect of diphosphonate treatment on phosphate transport by renal brush border vesicles
376. Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia
377. Renal transport of calcium, magnesium, and phosphate
378. +-dependent transport of phosphate across renal brush-border membrane
379. +-dependent inorganic-phosphate transporter NaPi-2 in thyroparathyroidectomized rats
380. Sodium-dependent phosphate cotransporters
381. +/phosphate cotransporter gene
382. Gene structure and functional analysis of the human Na/phosphate cotransporter
383. +-dependent inorganic phosphate transporters by 1,25-dihydroxyvitannin D-3: Identification of a vitamin D-responsive element in the human NAPI-3 gene
384. +-dependent phosphate cotransporter (NaPi-2) in rat kidney
385. Molecular cloning and hormonal regulation of P(i)T-1, a sodium-dependent phosphate cotransporter from rat parathyroid glands
386. Posttranscriptional mechanisms regulate ontogenic changes in rat renal sodium-phosphate transporter
387. X-linked hypophosphatemia-A homologous disorder in humans and mice
388. Renal Na-phosphate cotransporter gene expression in X-linked Hyp and Gy mice
389. +-phosphate cotransport in mouse distal convoluted tubule cells: Evidence for Glvr-1 and Ram-1 gene expression
390. + -P(i) cotransporter mRNA and immunoreactive protein in X-linked Hyp mice
391. Differential expression, abundance and regulation of Na-phosphate cotransporter genes in routine kidney
392. Renal Na phosphate cotransport in routine X-linked hypophosphatemic rickets, molecular characterization
393. Molecular genetics of mineral metabolic disorders
394. The role of renal chloride channel mutations in kidney stone disease and nephrocalcinosis
395. +-dependent uptake of D-glucose, phosphate and L-alanine in rat renal brush-border membrane vesicles
396. Isoproterenol increases renal tubular reabsorption of phosphate in X-linked hypophosphatemic (Hyp) mice
397. Hereditary hypophosphatemic rickets with hypercalciuria
398. Phosphate transport by the human renal cotransporter NaPi-3 expressed in HEK-293 cells
399. Expression and localization of a type II sodium-phosphate cotransporter in murine type II alveolar epithelial cells
400. Distribution of the sodium-phosphate transporter (NaPi-2) during the postnatal ontogeny of the rat kidney
401. Internalization of proximal tubular type II Na/P(i) cotransporter by parathyroid hormone: An immunogold electronmicroscopy study
402. 1-34 and 3-34 parathyroid hormone peptides downregulate proximal tubular type IIa Na/P(i) cotransporters but have different luminal vs. contraluminal actions
403. Phosphate transport by brush-border membranes from superficial and juxtamedullary cortex
404. Mechanism of glucocorticoid effect on renal transport of phosphate
405. Phosphate transport in the proximal convolution of the rat kidney. III. Effect of extracellular and intracellular pH
406. 2-Adrenoceptors and cellular cAMP levels in single nephron segments from the rat
407. Mechanism of phosphaturia elicited by administration of phosphonoformate in vivo
408. Cloning of a rabbit renal Na/P(i) cotransporter which is regulated by dietary phosphate
409. Sphingomyelin and cholesterol modulate sodium coupled uptakes in proximal tubular cells
410. +/phosphate cotransporter (NaPi-3) expressed in Xenopus oo-cytes by intracellular calcium and protein kinase C
411. Heavy metals inhibit P(i)-induced currents through human brush border NaPi-3 cotransporter in Xenopus oocytes
412. Human stanniocalcin inhibits renal phosphate exretion in the rat
413. Presence of multiple sodium-dependent phosphate transport processes in proximal brush-border membranes
414. Effect of dexamethasone on segmental phosphate reabsorption in phosphate deprived rats
415. Structure-function of recombinant Na/H-exchanger regulatory factor (NHE-RF)
416. Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush-border membrane Na-H exchanger
417. Na-dependent phosphate cotransporters: The NaPi protein families
418. Increase of Na/P(i) cotransport encoding mRNA in response to low P(i) diet in rat kidney cortex
419. Cloning and expression of cDNA for a Na/P(i) cotransport system of kidney cortex
420. Cloning and expression of a renal Na/P(i) cotransport system from flounder
421. A PDZ domain-containing protein with homology to Diphor-1 maps to human chromosome 1q21
422. Chromosomal localization of two human genes involved in phosphate homeostasis: The type IIb sodium-phosphate cotransporter and stanniocalcin
423. + antiport in proximal tubular BBM: Role of dopamine
424. The co-localization of stanniocalcin protein, mRNA and kidney cell markers in the rat kidney
425. Effects of phosphate and calcium infusion on renal phosphate txansport in the dog
426. Selective inhibition by epinephrine of parathyroid hormone-stimulated adenylate cyclase in rat renal cortex
427. Renal proximal tubular α-adrenergic receptors oppose urinary 3',5'-cyclic adenosine monophosphate response to parathyroid hormone in vivo
428. The Na/P(i) cotransporter of OK cells: Reaction and tentative identification with N-acetylimidazole
429. Involvement of disulphide bonds in the renal sodium/phosphate cotransporter NaP(i)-2
430. Hepatic sinusoidal membrane transport of anionic drugs mediated by anion transporter Npt 1
431. Dissociation of gluoconeogenesis from fluid and phosphate reabsorption in isolated rabbit proximal tubules
432. cAMP-mediated inhibition of the epithelial brush border Na/H exchanger, NHE3, requires an associated regulatory protein
433. Rat atrial natriuretic factor inhibits phosphate transport in brush-border membrane from superficial and juxtamedullary cortex
434. + gradient-dependent phosphate uptake across renal brush-border membrane
435. +-P(i) cotransport in renal brush-border membrane elicited by thyroid hormone
436. Differential properties of brush-border membrane vesicles from early and late proximal tubules of rat kidney
437. Modulatory effect of thyroid hormones on uptake of phosphate and other solutes across luminal brush-border membrane of kidney cortex
438. +/P(i) cotransport across the renal brush-border membrane
439. Role of sphingolipids in the regulation of renal phosphate transport
440. Calcitonin decreases the renal tubular capacity for phosphate reabsorption
441. +-phosphate cotransporter gene SLC17A2 to mouse chromosome band 13B by in situ hybridization