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Volumn 22, Issue 5, 2002, Pages 1698-1708

In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter

Author keywords

Behavioral analysis; Drosophila; Neuronal excitability; Neurotransmitter transporter; Overexpression phenotypes; Sodium channels

Indexed keywords

NEUROTRANSMITTER; SODIUM CHANNEL;

EID: 0036523034     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-05-01698.2002     Document Type: Article
Times cited : (27)

References (54)
  • 1
    • 0033603516 scopus 로고    scopus 로고
    • EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis
    • Alonso JM, Hirayama T, Roman G, Nourizadeh S, Ecker JR (1999) EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis. Science 284:2148-2152.
    • (1999) Science , vol.284 , pp. 2148-2152
    • Alonso, J.M.1    Hirayama, T.2    Roman, G.3    Nourizadeh, S.4    Ecker, J.R.5
  • 2
    • 0029055716 scopus 로고
    • Gliotactin, a novel transmembrane protein on peripheral glia, is required to form the blood-nerve barrier in Drosophila
    • Auld VJ, Fetter RD, Broadie K, Goodman CS (1995) Gliotactin, a novel transmembrane protein on peripheral glia, is required to form the blood-nerve barrier in Drosophila. Cell 81:757-767.
    • (1995) Cell , vol.81 , pp. 757-767
    • Auld, V.J.1    Fetter, R.D.2    Broadie, K.3    Goodman, C.S.4
  • 3
    • 0000592514 scopus 로고
    • Molecular organization of the maternal effect region of the Shaker complex of Drosophila: Characterization of an IA channel transcript with homology to vertebrate Na+ channel
    • Baumann A, Krah-Jentgens I, Mueller R, Muller-Holtkamp F, Seidel R, Kecskemethy N, Casal J, Ferrus A, Pongs O (1987) Molecular organization of the maternal effect region of the Shaker complex of Drosophila: Characterization of an IA channel transcript with homology to vertebrate Na+ channel. EMBO J 6:3419-3429.
    • (1987) EMBO J , vol.6 , pp. 3419-3429
    • Baumann, A.1    Krah-Jentgens, I.2    Mueller, R.3    Muller-Holtkamp, F.4    Seidel, R.5    Kecskemethy, N.6    Casal, J.7    Ferrus, A.8    Pongs, O.9
  • 5
    • 0030307610 scopus 로고    scopus 로고
    • Drosophila rosA gene, which when mutant causes aberrant photoreceptor oscillation, encodes a novel neurotransmitter transporter homologue
    • Burg MG, Geng C, Guan Y, Koliantz G, Pak WL (1996) Drosophila rosA gene, which when mutant causes aberrant photoreceptor oscillation, encodes a novel neurotransmitter transporter homologue. J Neurogenet 11:59-79.
    • (1996) J Neurogenet , vol.11 , pp. 59-79
    • Burg, M.G.1    Geng, C.2    Guan, Y.3    Koliantz, G.4    Pak, W.L.5
  • 6
    • 0029129194 scopus 로고
    • A potassium channel beta subunit related to the aldo-keto reductase super-family is encoded by the Drosophila hyperkinetic locus
    • Chouinard SW, Wilson GF, Schlimgen AK, Ganetzky B (1995) A potassium channel beta subunit related to the aldo-keto reductase super-family is encoded by the Drosophila hyperkinetic locus. Proc Natl Acad Sci USA 92:6763-6767.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6763-6767
    • Chouinard, S.W.1    Wilson, G.F.2    Schlimgen, A.K.3    Ganetzky, B.4
  • 7
    • 0029091192 scopus 로고
    • Cloning and functional analysis of tipE, a novel membrane protein that enhances Drosophila para sodium channel function
    • Feng G, Deak P, Chopra M, Hall LM (1995) Cloning and functional analysis of tipE, a novel membrane protein that enhances Drosophila para sodium channel function. Cell 82:1001-1011.
    • (1995) Cell , vol.82 , pp. 1001-1011
    • Feng, G.1    Deak, P.2    Chopra, M.3    Hall, L.M.4
  • 8
    • 0020041660 scopus 로고
    • Drosophila mutants with opposing effects on nerve excitability: Genetic and spatial interactions in repetitive firing
    • Ganetzky B, Wu CF (1982) Drosophila mutants with opposing effects on nerve excitability: Genetic and spatial interactions in repetitive firing. J Neurophysiol 47:501-514.
    • (1982) J Neurophysiol , vol.47 , pp. 501-514
    • Ganetzky, B.1    Wu, C.F.2
  • 9
    • 0021696514 scopus 로고
    • Genetic studies of membrane excitability in Drosophila: Lethal interaction between two temperature-sensitive paralytic mutations
    • Ganetzky B (1984) Genetic studies of membrane excitability in Drosophila: Lethal interaction between two temperature-sensitive paralytic mutations. Genetics 108:897-911.
    • (1984) Genetics , vol.108 , pp. 897-911
    • Ganetzky, B.1
  • 10
    • 0022653737 scopus 로고
    • Neurogenetic analysis of Drosophila mutations affecting sodium channels: Synergistic effects on viability and nerve conduction in double mutants involving tip-E
    • Ganetzky B (1986) Neurogenetic analysis of Drosophila mutations affecting sodium channels: Synergistic effects on viability and nerve conduction in double mutants involving tip-E. J Neurogenet 3:19-31.
    • (1986) J Neurogenet , vol.3 , pp. 19-31
    • Ganetzky, B.1
  • 11
    • 0022963398 scopus 로고
    • Neurogenetics of membrane excitability in Drosophila
    • Ganetzky B, Wu CF (1986) Neurogenetics of membrane excitability in Drosophila. Annu Rev Genet 20:13-44.
    • (1986) Annu Rev Genet , vol.20 , pp. 13-44
    • Ganetzky, B.1    Wu, C.F.2
  • 12
    • 0026471340 scopus 로고
    • Effects of kinesin mutations on neuronal functions
    • Gho M, McDonald K, Ganetzky B, Saxton WM (1992) Effects of kinesin mutations on neuronal functions. Science 258:313-316.
    • (1992) Science , vol.258 , pp. 313-316
    • Gho, M.1    McDonald, K.2    Ganetzky, B.3    Saxton, W.M.4
  • 13
    • 0032488659 scopus 로고    scopus 로고
    • Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning
    • Giese KP, Fedorov NB, Filipkowski RK, Silva AJ (1998) Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science 279:870-873.
    • (1998) Science , vol.279 , pp. 870-873
    • Giese, K.P.1    Fedorov, N.B.2    Filipkowski, R.K.3    Silva, A.J.4
  • 14
    • 0028803421 scopus 로고
    • Targeted ablation of glia disrupts axon tract formation in the Drosophila CNS
    • Hidalgo A, Urban J, Brand AH (1995) Targeted ablation of glia disrupts axon tract formation in the Drosophila CNS. Development 121:3703-3712.
    • (1995) Development , vol.121 , pp. 3703-3712
    • Hidalgo, A.1    Urban, J.2    Brand, A.H.3
  • 15
    • 0027973423 scopus 로고
    • Modulation of ion-channel function by G-protein-coupled receptors
    • Hille B (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 17:531-536.
    • (1994) Trends Neurosci , vol.17 , pp. 531-536
    • Hille, B.1
  • 16
    • 0036185936 scopus 로고    scopus 로고
    • The Drosophila inebriated-encoded neurotransmitter transporter: Dual roles in the control of neuronal excitability and the osmotic stress response
    • in press
    • Huang X, Huang Y, Chinnappan R, Bocchini C, Gustin MC, Stern M (2002) The Drosophila inebriated-encoded neurotransmitter transporter: Dual roles in the control of neuronal excitability and the osmotic stress response. Genetics, in press.
    • (2002) Genetics
    • Huang, X.1    Huang, Y.2    Chinnappan, R.3    Bocchini, C.4    Gustin, M.C.5    Stern, M.6
  • 17
    • 0029911064 scopus 로고    scopus 로고
    • Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila
    • Hurd DD, Saxton WM (1996) Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics 144:1075-1085.
    • (1996) Genetics , vol.144 , pp. 1075-1085
    • Hurd, D.D.1    Saxton, W.M.2
  • 18
    • 0021215867 scopus 로고
    • Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogaster
    • Jackson FR, Wilson SD, Strichartz GR, Hall LM (1984) Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogaster. Nature 308:189-191.
    • (1984) Nature , vol.308 , pp. 189-191
    • Jackson, F.R.1    Wilson, S.D.2    Strichartz, G.R.3    Hall, L.M.4
  • 19
    • 0026628322 scopus 로고
    • Transmitter release increases intracellular calcium in perisynaptic Schwann cells in situ
    • Jahromi BS, Robitaille R, Charlton MP (1992) Transmitter release increases intracellular calcium in perisynaptic Schwann cells in situ. Neuron 8:1069-1077.
    • (1992) Neuron , vol.8 , pp. 1069-1077
    • Jahromi, B.S.1    Robitaille, R.2    Charlton, M.P.3
  • 20
    • 0017089101 scopus 로고
    • Properties of the larval neuromuscular junction in Drosophila melanogaster
    • Jan LY, Jan YN (1976) Properties of the larval neuromuscular junction in Drosophila melanogaster. J Physiol (Lond) 262:189-214.
    • (1976) J Physiol (Lond) , vol.262 , pp. 189-214
    • Jan, L.Y.1    Jan, Y.N.2
  • 21
    • 0006941874 scopus 로고
    • Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction
    • Jan YN, Jan LY (1978) Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction. Proc Natl Acad Sci USA 75:515-519.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 515-519
    • Jan, Y.N.1    Jan, L.Y.2
  • 23
    • 0023669077 scopus 로고
    • Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel
    • Kamb A, Iverson LE, Tanouye MA (1987) Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Cell 50:405-413.
    • (1987) Cell , vol.50 , pp. 405-413
    • Kamb, A.1    Iverson, L.E.2    Tanouye, M.A.3
  • 24
    • 0029010806 scopus 로고
    • Neuropeptides, adenylyl cyclase, and memory storage
    • Kandel E, Abel T (1995) Neuropeptides, adenylyl cyclase, and memory storage. Science 268:825-826.
    • (1995) Science , vol.268 , pp. 825-826
    • Kandel, E.1    Abel, T.2
  • 25
    • 0019917243 scopus 로고
    • Molecular biology of learning: Modulation of transmitter release
    • Kandel ER, Schwartz JH (1982) Molecular biology of learning: Modulation of transmitter release. Science 218:433-443.
    • (1982) Science , vol.218 , pp. 433-443
    • Kandel, E.R.1    Schwartz, J.H.2
  • 26
    • 0014472969 scopus 로고
    • The behavior of four neurological mutants of Drosophila
    • rd (1969) The behavior of four neurological mutants of Drosophila. Genetics 61:399-409.
    • (1969) Genetics , vol.61 , pp. 399-409
    • Kaplan, W.D.1    Trout W E. III2
  • 27
    • 0025925276 scopus 로고
    • Napts, a mutation affecting sodium channel activity in Drosophila, is an allele of mle, a regulator of X chromosome transcription
    • Kernan MJ, Kuroda MI, Kreber R, Baker BS, Ganetzky B (1991) napts, a mutation affecting sodium channel activity in Drosophila, is an allele of mle, a regulator of X chromosome transcription. Cell 66:949-959.
    • (1991) Cell , vol.66 , pp. 949-959
    • Kernan, M.J.1    Kuroda, M.I.2    Kreber, R.3    Baker, B.S.4    Ganetzky, B.5
  • 28
    • 0020445890 scopus 로고
    • Temperature sensitive paralytic mutations on the 2nd and 3rd chromosomes of Drosophila melanogaster
    • Kulkarni SJ, Padhye A (1982) Temperature sensitive paralytic mutations on the 2nd and 3rd chromosomes of Drosophila melanogaster. Genet Res 40:191-200.
    • (1982) Genet Res , vol.40 , pp. 191-200
    • Kulkarni, S.J.1    Padhye, A.2
  • 29
    • 0024976602 scopus 로고
    • Molecular analysis of the para locus, a sodium channel gene in Drosophila
    • Loughney K, Kreber R, Ganetzky B (1989) Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell 58:1143-1154.
    • (1989) Cell , vol.58 , pp. 1143-1154
    • Loughney, K.1    Kreber, R.2    Ganetzky, B.3
  • 30
    • 0026110318 scopus 로고
    • Nerve terminal excitability and neuromuscular transmission in T(X;Y)V7 and Shaker mutants of Drosophila melanogaster
    • Mallart A, Angaut-Petit D, Bourret-Poulain C, Ferrus A (1991) Nerve terminal excitability and neuromuscular transmission in T(X;Y)V7 and Shaker mutants of Drosophila melanogaster. J Neurogenet 7:75-84.
    • (1991) J Neurogenet , vol.7 , pp. 75-84
    • Mallart, A.1    Angaut-Petit, D.2    Bourret-Poulain, C.3    Ferrus, A.4
  • 31
    • 0023807538 scopus 로고
    • Voltage-clamp analysis of sodium channels in wild-type and mutant Drosophila neurons
    • O'Dowd DK, Aldrich RW (1988) Voltage-clamp analysis of sodium channels in wild-type and mutant Drosophila neurons. J Neurosci 8:3633-3643.
    • (1988) J Neurosci , vol.8 , pp. 3633-3643
    • O'Dowd, D.K.1    Aldrich, R.W.2
  • 32
    • 0023225798 scopus 로고
    • Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila
    • Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY (1987) Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science 237:749-753.
    • (1987) Science , vol.237 , pp. 749-753
    • Papazian, D.M.1    Schwarz, T.L.2    Tempel, B.L.3    Jan, Y.N.4    Jan, L.Y.5
  • 33
    • 0030773837 scopus 로고    scopus 로고
    • Synaptic efficacy enhanced by glial cells in vitro
    • Pfrieger FW, Barres BA (1997) Synaptic efficacy enhanced by glial cells in vitro. Science 277:1684-1687.
    • (1997) Science , vol.277 , pp. 1684-1687
    • Pfrieger, F.W.1    Barres, B.A.2
  • 35
    • 0033057295 scopus 로고    scopus 로고
    • Conversion of lacZ enhancer trap lines to GAL4 lines using targeted transposition in Drosophila melanogaster
    • Sepp KJ, Auld VJ (1999) Conversion of lacZ enhancer trap lines to GAL4 lines using targeted transposition in Drosophila melanogaster. Genetics 151:1093-1101.
    • (1999) Genetics , vol.151 , pp. 1093-1101
    • Sepp, K.J.1    Auld, V.J.2
  • 36
    • 0004688543 scopus 로고
    • Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster
    • Siddiqi O, Benzer S (1976) Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster. Proc Natl Acad Sci USA 73:3253-3257.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3253-3257
    • Siddiqi, O.1    Benzer, S.2
  • 38
    • 0001868286 scopus 로고
    • P element-mediated transformation
    • (Roberts DB, ed). Washington, DC: IRL
    • Spradling A (1986) P element-mediated transformation. In: Drosophila - A Practical Approach (Roberts DB, ed), pp 175-197. Washington, DC: IRL.
    • (1986) Drosophila - A Practical Approach , pp. 175-197
    • Spradling, A.1
  • 39
    • 0024709832 scopus 로고
    • Altered synaptic transmission in Drosophila Hyperkinetic mutants
    • Stern M, Ganetzky B (1989) Altered synaptic transmission in Drosophila Hyperkinetic mutants. J Neurogenet 5:215-228.
    • (1989) J Neurogenet , vol.5 , pp. 215-228
    • Stern, M.1    Ganetzky, B.2
  • 40
    • 0026920582 scopus 로고
    • Identification and characterization of inebriated, a gene affecting neuronal excitability in Drosophila
    • Stern M, Ganetzky B (1992) Identification and characterization of inebriated, a gene affecting neuronal excitability in Drosophila. J Neurogenet 8:157-172.
    • (1992) J Neurogenet , vol.8 , pp. 157-172
    • Stern, M.1    Ganetzky, B.2
  • 41
    • 0025021560 scopus 로고
    • Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability
    • Stern M, Kreber R, Ganetzky B (1990) Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability. Genetics 124:133-143.
    • (1990) Genetics , vol.124 , pp. 133-143
    • Stern, M.1    Kreber, R.2    Ganetzky, B.3
  • 42
    • 0015056611 scopus 로고
    • Temperature-sensitive mutations in Drosophila melanogaster VII. A mutation (para-ts) causing reversible adult paralysis
    • Suzuki DT, Grigliatti T, Williamson R (1971) Temperature-sensitive mutations in Drosophila melanogaster. VII. A mutation (para-ts) causing reversible adult paralysis. Proc Natl Acad Sci USA 68:890-893.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 890-893
    • Suzuki, D.T.1    Grigliatti, T.2    Williamson, R.3
  • 43
    • 0023270432 scopus 로고
    • Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila
    • Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY (1987) Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science 237:770-775.
    • (1987) Science , vol.237 , pp. 770-775
    • Tempel, B.L.1    Papazian, D.M.2    Schwarz, T.L.3    Jan, Y.N.4    Jan, L.Y.5
  • 44
    • 18144435986 scopus 로고    scopus 로고
    • The highly integrated dialogue between neurons and astrocytes in brain function
    • Vesce S, Bezzi P, Volterra A (1999) The highly integrated dialogue between neurons and astrocytes in brain function. Sci Prog 82:251-270.
    • (1999) Sci Prog , vol.82 , pp. 251-270
    • Vesce, S.1    Bezzi, P.2    Volterra, A.3
  • 45
    • 0028578762 scopus 로고
    • Concomitant alterations of physiological and developmental plasticity in Drosophila CaM kinase II-inhibited synapses
    • Wang J, Renger JJ, Griffith LC, Greenspan RJ, Wu CF (1994) Concomitant alterations of physiological and developmental plasticity in Drosophila CaM kinase II-inhibited synapses. Neuron 13:1373-1384.
    • (1994) Neuron , vol.13 , pp. 1373-1384
    • Wang, J.1    Renger, J.J.2    Griffith, L.C.3    Greenspan, R.J.4    Wu, C.F.5
  • 46
    • 0025910233 scopus 로고
    • A distinct potassium channel polypeptide encoded by the Drosophila eag locus
    • Warmke J, Drysdale R, Ganetzky B (1991) A distinct potassium channel polypeptide encoded by the Drosophila eag locus. Science 252:1560-1562.
    • (1991) Science , vol.252 , pp. 1560-1562
    • Warmke, J.1    Drysdale, R.2    Ganetzky, B.3
  • 48
    • 0018944414 scopus 로고
    • Genetic alteration of nerve membrane excitability in temperature sensitive paralytic mutants of Drosophila melanogaster
    • Wu C-F, Ganetzky B (1980) Genetic alteration of nerve membrane excitability in temperature sensitive paralytic mutants of Drosophila melanogaster. Nature 286:814-816.
    • (1980) Nature , vol.286 , pp. 814-816
    • Wu, C.-F.1    Ganetzky, B.2
  • 49
    • 0026716793 scopus 로고
    • Neurogenetic studies of ion channels in Drosophila
    • Wu C-F, Ganetzky B (1992) Neurogenetic studies of ion channels in Drosophila. Ion Channels 3:261-314.
    • (1992) Ion Channels , vol.3 , pp. 261-314
    • Wu, C.-F.1    Ganetzky, B.2
  • 50
    • 0017388817 scopus 로고
    • Frequency characteristics in the visual system of Drosophila: Genetic dissection of electroretinogram components
    • Wu C-F, Wong F (1977) Frequency characteristics in the visual system of Drosophila: Genetic dissection of electroretinogram components. J Gen Physiol 69:705-724.
    • (1977) J Gen Physiol , vol.69 , pp. 705-724
    • Wu, C.-F.1    Wong, F.2
  • 51
    • 0039534396 scopus 로고
    • A Drosophila mutant with a temperature-sensitive block in nerve conduction
    • Wu C-F, Ganetzky B, Jan LY, Jan YN (1978) A Drosophila mutant with a temperature-sensitive block in nerve conduction. Proc Natl Acad Sci USA 75:4047-4051.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4047-4051
    • Wu, C.-F.1    Ganetzky, B.2    Jan, L.Y.3    Jan, Y.N.4
  • 53
    • 0033605123 scopus 로고    scopus 로고
    • A glial-neuronal signaling pathway revealed by mutations in a neurexin-related protein
    • Yuan LL, Ganetzky B (1999) A glial-neuronal signaling pathway revealed by mutations in a neurexin-related protein. Science 283:1343-1345.
    • (1999) Science , vol.283 , pp. 1343-1345
    • Yuan, L.L.1    Ganetzky, B.2
  • 54
    • 0025856667 scopus 로고
    • + currents in Drosophila muscle by mutations in eag
    • + currents in Drosophila muscle by mutations in eag. Science 252:1562-1564.
    • (1991) Science , vol.252 , pp. 1562-1564
    • Zhong, Y.1    Wu, C.F.2


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