메뉴 건너뛰기




Volumn 1, Issue 12, 2017, Pages 779-791

Proliferation through activation: Hemophagocytic lymphohistiocytosis in hematologic malignancy

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85056613315     PISSN: 24739529     EISSN: 24739537     Source Type: Journal    
DOI: 10.1182/bloodadvances.2017005561     Document Type: Review
Times cited : (32)

References (117)
  • 1
    • 77951640946 scopus 로고    scopus 로고
    • A method and server for predicting damaging missense mutations
    • Adzhubei IA, Schmidt S, Peshkin L, et al. A method and server for predicting damaging missense mutations. Nat Methods. 2010;7(4):248-249.
    • (2010) Nat Methods , vol.7 , Issue.4 , pp. 248-249
    • Adzhubei, I.A.1    Schmidt, S.2    Peshkin, L.3
  • 2
    • 0034847883 scopus 로고    scopus 로고
    • Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis
    • Clementi R, zur Stadt U, Savoldi G, et al. Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis. J Med Genet. 2001;38(9):643-646.
    • (2001) J Med Genet , vol.38 , Issue.9 , pp. 643-646
    • Clementi, R.1    zur Stadt, U.2    Savoldi, G.3
  • 3
    • 19344369831 scopus 로고    scopus 로고
    • A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis
    • Voskoboinik I, Thia M-C, Trapani JA. A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis. Blood. 2005;105(12):4700-4706.
    • (2005) Blood , vol.105 , Issue.12 , pp. 4700-4706
    • Voskoboinik, I.1    Thia, M.-C.2    Trapani, J.A.3
  • 4
    • 84878384497 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: An update on diagnosis and pathogenesis
    • Rosado FGN, Kim AS. Hemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesis. Am J Clin Pathol. 2013;139(6):713-727.
    • (2013) Am J Clin Pathol , vol.139 , Issue.6 , pp. 713-727
    • Rosado, F.G.N.1    Kim, A.S.2
  • 5
    • 0000372673 scopus 로고
    • Familial haemophagocytic reticulosis
    • Farquhar JW, Claireaux AE. Familial haemophagocytic reticulosis. Arch Dis Child. 1952;27(136):519-525.
    • (1952) Arch Dis Child , vol.27 , Issue.136 , pp. 519-525
    • Farquhar, J.W.1    Claireaux, A.E.2
  • 6
    • 33845619137 scopus 로고    scopus 로고
    • HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
    • Henter J-I, Horne A, Aricó M, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124-131.
    • (2007) Pediatr Blood Cancer , vol.48 , Issue.2 , pp. 124-131
    • Henter, J.-I.1    Horne, A.2    Aricó, M.3
  • 7
    • 84877819974 scopus 로고    scopus 로고
    • Advances in understanding the pathogenesis of HLH
    • Usmani GN, Woda BA, Newburger PE. Advances in understanding the pathogenesis of HLH. Br J Haematol. 2013;161(5):609-622.
    • (2013) Br J Haematol , vol.161 , Issue.5 , pp. 609-622
    • Usmani, G.N.1    Woda, B.A.2    Newburger, P.E.3
  • 8
    • 85006147261 scopus 로고    scopus 로고
    • Killing of microbes and cancer by the immune system with three mammalian pore-forming killer proteins
    • Podack ER, Munson GP. Killing of microbes and cancer by the immune system with three mammalian pore-forming killer proteins. Front Immunol. 2016;7:464.
    • (2016) Front Immunol , vol.7 , pp. 464
    • Podack, E.R.1    Munson, G.P.2
  • 9
    • 70350471155 scopus 로고    scopus 로고
    • Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection
    • Lee S-H, Kim K-S, Fodil-Cornu N, Vidal SM, Biron CA. Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection. J Exp Med. 2009;206(10):2235-2251.
    • (2009) J Exp Med , vol.206 , Issue.10 , pp. 2235-2251
    • Lee, S.-H.1    Kim, K.-S.2    Fodil-Cornu, N.3    Vidal, S.M.4    Biron, C.A.5
  • 10
    • 33745486749 scopus 로고    scopus 로고
    • CD41CD251 Tregs and NKT cells: Regulators regulating regulators
    • La Cava A, Van Kaer L, Fu-Dong-Shi. CD41CD251 Tregs and NKT cells: regulators regulating regulators. Trends Immunol. 2006;27(7):322-327.
    • (2006) Trends Immunol , vol.27 , Issue.7 , pp. 322-327
    • la Cava, A.1    van Kaer, L.2    Fu-Dong-Shi3
  • 11
    • 85041010320 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in children: Pathogenesis and treatment
    • Ishii E. Hemophagocytic lymphohistiocytosis in children: pathogenesis and treatment. Front Pediatr. 2016;4:47.
    • (2016) Front Pediatr , vol.4 , pp. 47
    • Ishii, E.1
  • 12
    • 0033520970 scopus 로고    scopus 로고
    • Perforin gene defects in familial hemophagocytic lymphohistiocytosis
    • Stepp SE, Dufourcq-Lagelouse R, Le Deist F, et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science. 1999;286(5446):1957-1959.
    • (1999) Science , vol.286 , Issue.5446 , pp. 1957-1959
    • Stepp, S.E.1    Dufourcq-Lagelouse, R.2    Le Deist, F.3
  • 13
    • 10744224641 scopus 로고    scopus 로고
    • Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
    • Feldmann J, Callebaut I, Raposo G, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell. 2003;115(4):461-473.
    • (2003) Cell , vol.115 , Issue.4 , pp. 461-473
    • Feldmann, J.1    Callebaut, I.2    Raposo, G.3
  • 14
    • 20144363940 scopus 로고    scopus 로고
    • Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
    • zur Stadt U, Schmidt S, Kasper B, et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet. 2005;14(6):827-834.
    • (2005) Hum Mol Genet , vol.14 , Issue.6 , pp. 827-834
    • zur Stadt, U.1    Schmidt, S.2    Kasper, B.3
  • 15
    • 72849125357 scopus 로고    scopus 로고
    • Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
    • Côte M, Ménager MM, Burgess A, et al. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest. 2009;119(12):3765-3773.
    • (2009) J Clin Invest , vol.119 , Issue.12 , pp. 3765-3773
    • Côte, M.1    Ménager, M.M.2    Burgess, A.3
  • 16
    • 84929612515 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis (HLH): A heterogeneous spectrum of cytokine-driven immune disorders
    • Brisse E, Wouters CH, Matthys P. Hemophagocytic lymphohistiocytosis (HLH): a heterogeneous spectrum of cytokine-driven immune disorders. Cytokine Growth Factor Rev. 2015;26(3):263-280.
    • (2015) Cytokine Growth Factor Rev , vol.26 , Issue.3 , pp. 263-280
    • Brisse, E.1    Wouters, C.H.2    Matthys, P.3
  • 17
    • 84881504826 scopus 로고    scopus 로고
    • Clinical characteristics and outcomes of Chédiak-Higashi syndrome: A nationwide survey of Japan
    • Nagai K, Ochi F, Terui K, et al. Clinical characteristics and outcomes of Chédiak-Higashi syndrome: a nationwide survey of Japan. Pediatr Blood Cancer. 2013;60(10):1582-1586.
    • (2013) Pediatr Blood Cancer , vol.60 , Issue.10 , pp. 1582-1586
    • Nagai, K.1    Ochi, F.2    Terui, K.3
  • 18
    • 77649154766 scopus 로고    scopus 로고
    • Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations
    • Meeths M, Bryceson YT, Rudd E, et al. Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Pediatr Blood Cancer. 2010;54(4):563-572.
    • (2010) Pediatr Blood Cancer , vol.54 , Issue.4 , pp. 563-572
    • Meeths, M.1    Bryceson, Y.T.2    Rudd, E.3
  • 19
    • 84879456568 scopus 로고    scopus 로고
    • The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2
    • Jessen B, Bode SFN, Ammann S, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121(15): 2943-2951.
    • (2013) Blood , vol.121 , Issue.15 , pp. 2943-2951
    • Jessen, B.1    Bode, S.F.N.2    Ammann, S.3
  • 20
    • 79551644967 scopus 로고    scopus 로고
    • Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)
    • Pachlopnik Schmid J, Canioni D, Moshous D, et al. Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency). Blood. 2011;117(5):1522-1529.
    • (2011) Blood , vol.117 , Issue.5 , pp. 1522-1529
    • Pachlopnik Schmid, J.1    Canioni, D.2    Moshous, D.3
  • 21
    • 84938935536 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-g receptor deficiency
    • Tesi B, Sieni E, Neves C, et al. Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-g receptor deficiency. J Allergy Clin Immunol. 2015;135(6):1638-1641.
    • (2015) J Allergy Clin Immunol , vol.135 , Issue.6 , pp. 1638-1641
    • Tesi, B.1    Sieni, E.2    Neves, C.3
  • 22
    • 84912042007 scopus 로고    scopus 로고
    • Interleukin-2-inducible T-cell kinase (ITK) deficiency - Clinical and molecular aspects
    • Ghosh S, Bienemann K, Boztug K, Borkhardt A. Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects. J Clin Immunol. 2014;34(8):892-899.
    • (2014) J Clin Immunol , vol.34 , Issue.8 , pp. 892-899
    • Ghosh, S.1    Bienemann, K.2    Boztug, K.3    Borkhardt, A.4
  • 23
    • 0024415167 scopus 로고
    • Natural killer cell function and interferon production in familial hemophagocytic lymphohistiocytosis
    • Eife R, Janka GE, Belohradsky BH, Holtmann H. Natural killer cell function and interferon production in familial hemophagocytic lymphohistiocytosis. Pediatr Hematol Oncol. 1989;6(3):265-272.
    • (1989) Pediatr Hematol Oncol , vol.6 , Issue.3 , pp. 265-272
    • Eife, R.1    Janka, G.E.2    Belohradsky, B.H.3    Holtmann, H.4
  • 25
    • 84969964497 scopus 로고    scopus 로고
    • Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: A systematic scoping review
    • Hayden A, Park S, Giustini D, Lee AYY, Chen LYC. Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: A systematic scoping review. Blood Rev. 2016;30(6):411-420.
    • (2016) Blood Rev , vol.30 , Issue.6 , pp. 411-420
    • Hayden, A.1    Park, S.2    Giustini, D.3    Lee, A.Y.Y.4    Chen, L.Y.C.5
  • 26
    • 84955175704 scopus 로고    scopus 로고
    • Clinical significance of bone marrow hemophagocytosis in adult patients with malignancy and non-malignancy-induced hemophagocytic lymphohistiocytosis
    • Lim SH, Park S, Jang JH, et al. Clinical significance of bone marrow hemophagocytosis in adult patients with malignancy and non-malignancy-induced hemophagocytic lymphohistiocytosis. Ann Hematol. 2016;95(2):325-335.
    • (2016) Ann Hematol , vol.95 , Issue.2 , pp. 325-335
    • Lim, S.H.1    Park, S.2    Jang, J.H.3
  • 27
    • 84977523048 scopus 로고    scopus 로고
    • Elevated circulating levels of interferon-g and interferon-g-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
    • Bracaglia C, de Graaf K, Pires Marafon D, et al. Elevated circulating levels of interferon-g and interferon-g-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2017;76(1):166-172.
    • (2017) Ann Rheum Dis , vol.76 , Issue.1 , pp. 166-172
    • Bracaglia, C.1    de Graaf, K.2    Pires Marafon, D.3
  • 28
    • 51349098155 scopus 로고    scopus 로고
    • Cytokines as a key component of cancer-related inflammation
    • Germano G, Allavena P, Mantovani A. Cytokines as a key component of cancer-related inflammation. Cytokine. 2008;43(3):374-379.
    • (2008) Cytokine , vol.43 , Issue.3 , pp. 374-379
    • Germano, G.1    Allavena, P.2    Mantovani, A.3
  • 29
    • 84919419009 scopus 로고    scopus 로고
    • A case of hemophagocytic lymphohistiocytosis in a patient with chronic lymphocytic leukemia after treatment with fludarabine, cyclophosphamide, and rituximab chemotherapy, with autopsy findings
    • Tiong IS, Lau MBY, Toumoua S, Chiruka S. A case of hemophagocytic lymphohistiocytosis in a patient with chronic lymphocytic leukemia after treatment with fludarabine, cyclophosphamide, and rituximab chemotherapy, with autopsy findings. Case Rep Hematol. 2012;2012:326053.
    • (2012) Case Rep Hematol , vol.2012 , pp. 326053
    • Tiong, I.S.1    Lau, M.B.Y.2    Toumoua, S.3    Chiruka, S.4
  • 30
    • 84903132528 scopus 로고    scopus 로고
    • Hemophagocytic syndromes–an update
    • Janka GE, Lehmberg K. Hemophagocytic syndromes–an update. Blood Rev. 2014;28(4):135-142.
    • (2014) Blood Rev , vol.28 , Issue.4 , pp. 135-142
    • Janka, G.E.1    Lehmberg, K.2
  • 31
    • 84904097189 scopus 로고    scopus 로고
    • Current concepts in the diagnosis and management of cytokine release syndrome
    • published correction Blood. 2015;126(8):1048
    • Lee DW, Gardner R, Porter DL, et al. Current concepts in the diagnosis and management of cytokine release syndrome [published correction appears in Blood. 2015;126(8):1048]. Blood. 2014;124(2):188-195.
    • (2014) Blood , vol.124 , Issue.2 , pp. 188-195
    • Lee, D.W.1    Gardner, R.2    Porter, D.L.3
  • 32
    • 79551657911 scopus 로고    scopus 로고
    • The emerging role of interleukin-1b in autoinflammatory diseases
    • Lachmann HJ, Quartier P, So A, Hawkins PN. The emerging role of interleukin-1b in autoinflammatory diseases. Arthritis Rheum. 2011;63(2):314-324.
    • (2011) Arthritis Rheum , vol.63 , Issue.2 , pp. 314-324
    • Lachmann, H.J.1    Quartier, P.2    So, A.3    Hawkins, P.N.4
  • 33
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357(9255):539-545.
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 34
    • 84905914440 scopus 로고    scopus 로고
    • Assessment of cytokine expression profile in acute myeloid leukemia patients before and after chemotherapy
    • Sepehrizadeh Z, Mohammadi M, Emami A, et al. Assessment of cytokine expression profile in acute myeloid leukemia patients before and after chemotherapy. Turk J Haematol. 2014;31(2):149-154.
    • (2014) Turk J Haematol , vol.31 , Issue.2 , pp. 149-154
    • Sepehrizadeh, Z.1    Mohammadi, M.2    Emami, A.3
  • 35
    • 0038312244 scopus 로고    scopus 로고
    • Characteristic cytokine generation patterns in cancer cells and infiltrating lymphocytes in oral squamous cell carcinomas and the influence of chemoradiation combined with immunotherapy on these patterns
    • Yamamoto T, Kimura T, Ueta E, Tatemoto Y, Osaki T. Characteristic cytokine generation patterns in cancer cells and infiltrating lymphocytes in oral squamous cell carcinomas and the influence of chemoradiation combined with immunotherapy on these patterns. Oncology. 2003;64(4):407-415.
    • (2003) Oncology , vol.64 , Issue.4 , pp. 407-415
    • Yamamoto, T.1    Kimura, T.2    Ueta, E.3    Tatemoto, Y.4    Osaki, T.5
  • 36
    • 84902338091 scopus 로고    scopus 로고
    • Haemophagocytic lymphohistiocytosis following fludarabine/cyclophosphamide chemotherapy for chronic lymphocytic leukaemia
    • Jayakody Arachchillage D, Hurst E, Carey P, et al. Haemophagocytic lymphohistiocytosis following fludarabine/cyclophosphamide chemotherapy for chronic lymphocytic leukaemia. Br J Haematol. 2014;166(1):142-145.
    • (2014) Br J Haematol , vol.166 , Issue.1 , pp. 142-145
    • Jayakody Arachchillage, D.1    Hurst, E.2    Carey, P.3
  • 37
    • 84952863614 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis after initiation of chemotherapy for bilateral adrenal neuroblastoma
    • Nascimento FA, Nery J, Trennepohl J, Pianovski MAD. Hemophagocytic lymphohistiocytosis after initiation of chemotherapy for bilateral adrenal neuroblastoma. J Pediatr Hematol Oncol. 2016;38(1):e13-e15.
    • (2016) J Pediatr Hematol Oncol , vol.38 , Issue.1 , pp. e13-e15
    • Nascimento, F.A.1    Nery, J.2    Trennepohl, J.3    Pianovski, M.A.D.4
  • 38
    • 3242752040 scopus 로고    scopus 로고
    • An animal model of hemophagocytic lymphohistiocytosis (HLH): CD81 T cells and interferon gamma are essential for the disorder
    • Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD81 T cells and interferon gamma are essential for the disorder. Blood. 2004;104(3):735-743.
    • (2004) Blood , vol.104 , Issue.3 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3    Marrack, P.4
  • 39
    • 0032101604 scopus 로고    scopus 로고
    • Aplastic anemia rescued by exhaustion of cytokine-secreting CD81 T cells in persistent infection with lymphocytic choriomeningitis virus
    • Binder D, van den Broek MF, Kägi D, et al. Aplastic anemia rescued by exhaustion of cytokine-secreting CD81 T cells in persistent infection with lymphocytic choriomeningitis virus. J Exp Med. 1998;187(11):1903-1920.
    • (1998) J Exp Med , vol.187 , Issue.11 , pp. 1903-1920
    • Binder, D.1    van den Broek, M.F.2    Kägi, D.3
  • 40
    • 70449453484 scopus 로고    scopus 로고
    • Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- And Rab27adeficient mice
    • Pachlopnik Schmid J, Ho C-H, Chrétien F, et al. Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27adeficient mice. EMBO Mol Med. 2009;1(2):112-124.
    • (2009) EMBO Mol Med , vol.1 , Issue.2 , pp. 112-124
    • Pachlopnik Schmid, J.1    Ho, C.-H.2    Chrétien, F.3
  • 41
    • 84989271383 scopus 로고    scopus 로고
    • High level of perforin expression is required for effective correction of hemophagocytic lymphohistiocytosis
    • published online ahead of print 29 July 2016
    • Tiwari S, Hontz A, Terrell CE, et al. High level of perforin expression is required for effective correction of hemophagocytic lymphohistiocytosis [published online ahead of print 29 July 2016]. Hum Gene Ther. doi:10.1089/hum.2016.065.
    • Hum Gene Ther
    • Tiwari, S.1    Hontz, A.2    Terrell, C.E.3
  • 42
    • 84861526602 scopus 로고    scopus 로고
    • Diagnostic accuracy of a specific cytokine pattern in hemophagocytic lymphohistiocytosis in children
    • e1
    • Xu X-J, Tang Y-M, Song H, et al. Diagnostic accuracy of a specific cytokine pattern in hemophagocytic lymphohistiocytosis in children. J Pediatr. 2012; 160(6):984-90.e1.
    • (2012) J Pediatr , vol.160 , Issue.6
    • Xu, X.-J.1    Tang, Y.-M.2    Song, H.3
  • 43
    • 84884187508 scopus 로고    scopus 로고
    • Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(1) T cells and dendritic cells
    • Terrell CE, Jordan MB. Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(1) T cells and dendritic cells. Blood. 2013; 121(26):5184-5191.
    • (2013) Blood , vol.121 , Issue.26 , pp. 5184-5191
    • Terrell, C.E.1    Jordan, M.B.2
  • 44
    • 58149396438 scopus 로고    scopus 로고
    • Association of monoclonal expansion of Epstein-Barr virus-negative CD158a1 NK cells secreting large amounts of gamma interferon with hemophagocytic lymphohistiocytosis
    • López-Alvarez MR, Martínez-Sánchez MV, Salgado-Cecilia MG, et al. Association of monoclonal expansion of Epstein-Barr virus-negative CD158a1 NK cells secreting large amounts of gamma interferon with hemophagocytic lymphohistiocytosis. Clin Vaccine Immunol. 2009;16(1):142-145.
    • (2009) Clin Vaccine Immunol , vol.16 , Issue.1 , pp. 142-145
    • López-Alvarez, M.R.1    Martínez-Sánchez, M.V.2    Salgado-Cecilia, M.G.3
  • 45
    • 78751703756 scopus 로고    scopus 로고
    • Interferon-g secretion by t(9;22) acute lymphoblastic leukemia-derived dendritic cells
    • Brady MT, Lee J, Ferrone S, Wang ES, Wetzler M. Interferon-g secretion by t(9;22) acute lymphoblastic leukemia-derived dendritic cells. Leuk Res. 2011; 35(2):275-277.
    • (2011) Leuk Res , vol.35 , Issue.2 , pp. 275-277
    • Brady, M.T.1    Lee, J.2    Ferrone, S.3    Wang, E.S.4    Wetzler, M.5
  • 46
    • 84949971589 scopus 로고    scopus 로고
    • Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis
    • Tesi B, Lagerstedt-Robinson K, Chiang SCC, et al. Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis. Genome Med. 2015;7:130.
    • (2015) Genome Med , vol.7 , pp. 130
    • Tesi, B.1    Lagerstedt-Robinson, K.2    Chiang, S.C.C.3
  • 47
    • 84994085057 scopus 로고    scopus 로고
    • Molecular mechanisms of regulation of Toll-like receptor signaling
    • Leifer CA, Medvedev AE. Molecular mechanisms of regulation of Toll-like receptor signaling. J Leukoc Biol. 2016;100(5):927-941.
    • (2016) J Leukoc Biol , vol.100 , Issue.5 , pp. 927-941
    • Leifer, C.A.1    Medvedev, A.E.2
  • 48
    • 79959242566 scopus 로고    scopus 로고
    • Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
    • Krebs P, Crozat K, Popkin D, Oldstone MB, Beutler B. Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice. Blood. 2011;117(24):6582-6588.
    • (2011) Blood , vol.117 , Issue.24 , pp. 6582-6588
    • Krebs, P.1    Crozat, K.2    Popkin, D.3    Oldstone, M.B.4    Beutler, B.5
  • 49
    • 79957889288 scopus 로고    scopus 로고
    • Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice
    • Behrens EM, Canna SW, Slade K, et al. Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. J Clin Invest. 2011; 121(6):2264-2277.
    • (2011) J Clin Invest , vol.121 , Issue.6 , pp. 2264-2277
    • Behrens, E.M.1    Canna, S.W.2    Slade, K.3
  • 50
    • 84992126289 scopus 로고    scopus 로고
    • The role of Toll-like receptors in hematopoietic malignancies
    • Monlish DA, Bhatt ST, Schuettpelz LG. The role of Toll-like receptors in hematopoietic malignancies. Front Immunol. 2016;7(390):390.
    • (2016) Front Immunol , vol.7 , Issue.390 , pp. 390
    • Monlish, D.A.1    Bhatt, S.T.2    Schuettpelz, L.G.3
  • 51
    • 73849121794 scopus 로고    scopus 로고
    • Identification of miR-145 and miR-146a as mediators of the 5q- Syndrome phenotype
    • Starczynowski DT, Kuchenbauer F, Argiropoulos B, et al. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med. 2010;16(1):49-58.
    • (2010) Nat Med , vol.16 , Issue.1 , pp. 49-58
    • Starczynowski, D.T.1    Kuchenbauer, F.2    Argiropoulos, B.3
  • 52
    • 74049146800 scopus 로고    scopus 로고
    • Polymorphisms and haplotypes in TLR9 and MYD88 are associated with the development of Hodgkin’s lymphoma: A candidate-gene association study
    • Mollaki V, Georgiadis T, Tassidou A, et al. Polymorphisms and haplotypes in TLR9 and MYD88 are associated with the development of Hodgkin’s lymphoma: a candidate-gene association study. J Hum Genet. 2009;54(11):655-659.
    • (2009) J Hum Genet , vol.54 , Issue.11 , pp. 655-659
    • Mollaki, V.1    Georgiadis, T.2    Tassidou, A.3
  • 53
    • 84923854434 scopus 로고    scopus 로고
    • The expression of Toll-like receptors in patients with acute myeloid leukemia treated with induction chemotherapy
    • Rybka J, Butrym A, Wróbel T, et al. The expression of Toll-like receptors in patients with acute myeloid leukemia treated with induction chemotherapy. Leuk Res. 2015;39(3):318-322.
    • (2015) Leuk Res , vol.39 , Issue.3 , pp. 318-322
    • Rybka, J.1    Butrym, A.2    Wróbel, T.3
  • 54
    • 79551686422 scopus 로고    scopus 로고
    • Oncogenically active MYD88 mutations in human lymphoma
    • Ngo VN, Young RM, Schmitz R, et al. Oncogenically active MYD88 mutations in human lymphoma. Nature. 2011;470(7332):115-119.
    • (2011) Nature , vol.470 , Issue.7332 , pp. 115-119
    • Ngo, V.N.1    Young, R.M.2    Schmitz, R.3
  • 55
    • 84924322584 scopus 로고    scopus 로고
    • NF-kB is crucial in proximal T-cell signaling for calcium influx and NFAT activation
    • Bronk CC, Yoder S, Hopewell EL, et al. NF-kB is crucial in proximal T-cell signaling for calcium influx and NFAT activation. Eur J Immunol. 2014;44(12): 3741-3746.
    • (2014) Eur J Immunol , vol.44 , Issue.12 , pp. 3741-3746
    • Bronk, C.C.1    Yoder, S.2    Hopewell, E.L.3
  • 56
    • 34547842304 scopus 로고    scopus 로고
    • Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: Nuclear factor-kappa B pathway as a potential therapeutic target
    • Chuang H-C, Lay J-D, Hsieh W-C, Su I-J. Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: nuclear factor-kappa B pathway as a potential therapeutic target. Cancer Sci. 2007;98(9):1281-1287.
    • (2007) Cancer Sci , vol.98 , Issue.9 , pp. 1281-1287
    • Chuang, H.-C.1    Lay, J.-D.2    Hsieh, W.-C.3    Su, I.-J.4
  • 57
    • 84872065897 scopus 로고    scopus 로고
    • JAKs and STATs in immunity, immunodeficiency, and cancer
    • O’Shea JJ, Holland SM, Staudt LM. JAKs and STATs in immunity, immunodeficiency, and cancer. N Engl J Med. 2013;368(2):161-170.
    • (2013) N Engl J Med , vol.368 , Issue.2 , pp. 161-170
    • O’Shea, J.J.1    Holland, S.M.2    Staudt, L.M.3
  • 58
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling: From interferons to cytokines
    • Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem. 2007;282(28):20059-20063.
    • (2007) J Biol Chem , vol.282 , Issue.28 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 59
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O’Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell. 2002;109(Suppl):S121-S131.
    • (2002) Cell , vol.109 , pp. S121-S131
    • O’Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 60
    • 85017075036 scopus 로고    scopus 로고
    • Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis
    • Das R, Guan P, Sprague L, et al. Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis. Blood. 2016;127(13):1666-1675.
    • (2016) Blood , vol.127 , Issue.13 , pp. 1666-1675
    • Das, R.1    Guan, P.2    Sprague, L.3
  • 61
    • 13544273826 scopus 로고    scopus 로고
    • Macrophage activation syndrome: Characteristic findings on liver biopsy illustrating the key role of activated, IFN-g-producing lymphocytes and IL-6- And TNF-a-producing macrophages
    • Billiau AD, Roskams T, Van Damme-Lombaerts R, Matthys P, Wouters C. Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-g-producing lymphocytes and IL-6- and TNF-a-producing macrophages. Blood. 2005;105(4):1648-1651.
    • (2005) Blood , vol.105 , Issue.4 , pp. 1648-1651
    • Billiau, A.D.1    Roskams, T.2    van Damme-Lombaerts, R.3    Matthys, P.4    Wouters, C.5
  • 62
    • 17744414197 scopus 로고    scopus 로고
    • Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis
    • Osugi Y, Hara J, Tagawa S, et al. Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood. 1997;89(11): 4100-4103.
    • (1997) Blood , vol.89 , Issue.11 , pp. 4100-4103
    • Osugi, Y.1    Hara, J.2    Tagawa, S.3
  • 63
    • 84957071786 scopus 로고    scopus 로고
    • Protumoral TSP50 regulates macrophage activities and polarization via production of TNF-a and IL-1b, and activation of the NF-kB signaling pathway
    • Yang C, Zhang D-M, Song Z-B, et al. Protumoral TSP50 regulates macrophage activities and polarization via production of TNF-a and IL-1b, and activation of the NF-kB signaling pathway. PLoS One. 2015;10(12):e0145095.
    • (2015) PLoS One , vol.10 , Issue.12
    • Yang, C.1    Zhang, D.-M.2    Song, Z.-B.3
  • 64
    • 0027461967 scopus 로고
    • Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies
    • Weber J, Yang JC, Topalian SL, et al. Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies. J Clin Oncol. 1993;11(3):499-506.
    • (1993) J Clin Oncol , vol.11 , Issue.3 , pp. 499-506
    • Weber, J.1    Yang, J.C.2    Topalian, S.L.3
  • 65
    • 46149083954 scopus 로고    scopus 로고
    • Understanding organ dysfunction in hemophagocytic lymphohistiocytosis
    • Créput C, Galicier L, Buyse S, Azoulay E. Understanding organ dysfunction in hemophagocytic lymphohistiocytosis. Intensive Care Med. 2008;34(7):1177-1187.
    • (2008) Intensive Care Med , vol.34 , Issue.7 , pp. 1177-1187
    • Créput, C.1    Galicier, L.2    Buyse, S.3    Azoulay, E.4
  • 66
    • 0036120669 scopus 로고    scopus 로고
    • Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens
    • Biet F, Locht C, Kremer L. Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens. J Mol Med (Berl). 2002; 80(3):147-162.
    • (2002) J Mol Med (Berl , vol.80 , Issue.3 , pp. 147-162
    • Biet, F.1    Locht, C.2    Kremer, L.3
  • 67
    • 77649267675 scopus 로고    scopus 로고
    • Failure of interferon g to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis
    • Nold-Petry CA, Lehrnbecher T, Jarisch A, et al. Failure of interferon g to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis. PLoS One. 2010;5(1):e8663.
    • (2010) PLoS One , vol.5 , Issue.1
    • Nold-Petry, C.A.1    Lehrnbecher, T.2    Jarisch, A.3
  • 68
    • 84927610290 scopus 로고    scopus 로고
    • A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice
    • Sepulveda FE, Maschalidi S, Vosshenrich CAJ, et al. A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice. Blood. 2015;125(9):1427-1434.
    • (2015) Blood , vol.125 , Issue.9 , pp. 1427-1434
    • Sepulveda, F.E.1    Maschalidi, S.2    Vosshenrich, C.A.J.3
  • 70
    • 52249093922 scopus 로고    scopus 로고
    • Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis
    • Tamura K, Kanazawa T, Tsukada S, Kobayashi T, Kawamura M, Morikawa A. Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2008;51(5):662-668.
    • (2008) Pediatr Blood Cancer , vol.51 , Issue.5 , pp. 662-668
    • Tamura, K.1    Kanazawa, T.2    Tsukada, S.3    Kobayashi, T.4    Kawamura, M.5    Morikawa, A.6
  • 71
    • 85008384558 scopus 로고    scopus 로고
    • The maze of diagnosing hemophagocytic lymphohistiocytosis: Single-center experience of a series of 6 clinical cases
    • Hanoun M, Dührsen U. The maze of diagnosing hemophagocytic lymphohistiocytosis: single-center experience of a series of 6 clinical cases. Oncology. 2017;92(3):173-178.
    • (2017) Oncology , vol.92 , Issue.3 , pp. 173-178
    • Hanoun, M.1    Dührsen, U.2
  • 72
    • 85013689957 scopus 로고    scopus 로고
    • Performances of the H-score for diagnosis of hemophagocytic lymphohistiocytosis in adult and pediatric patients
    • Debaugnies F, Mahadeb B, Ferster A, et al. Performances of the H-score for diagnosis of hemophagocytic lymphohistiocytosis in adult and pediatric patients. Am J Clin Pathol. 2016;145(6):862-870.
    • (2016) Am J Clin Pathol , vol.145 , Issue.6 , pp. 862-870
    • Debaugnies, F.1    Mahadeb, B.2    Ferster, A.3
  • 73
    • 84979650472 scopus 로고    scopus 로고
    • Risk of hemophagocytic lymphohistiocytosis in adults with fevers of unknown origin: The clinical utility of a new scoring system on early detection
    • published online ahead of print 28 July 2016
    • Wang H-Y, Yang C-F, Chiou T-J, et al. Risk of hemophagocytic lymphohistiocytosis in adults with fevers of unknown origin: the clinical utility of a new scoring system on early detection [published online ahead of print 28 July 2016]. Hematol Oncol. doi:10.1002/hon.2333.
    • Hematol Oncol
    • Wang, H.-Y.1    Yang, C.-F.2    Chiou, T.-J.3
  • 74
    • 84898872294 scopus 로고    scopus 로고
    • A high sIL-2R/ferritin ratio is a useful marker for the diagnosis of lymphoma-associated hemophagocytic syndrome
    • Tsuji T, Hirano T, Yamasaki H, Tsuji M, Tsuda H. A high sIL-2R/ferritin ratio is a useful marker for the diagnosis of lymphoma-associated hemophagocytic syndrome. Ann Hematol. 2014;93(5):821-826.
    • (2014) Ann Hematol , vol.93 , Issue.5 , pp. 821-826
    • Tsuji, T.1    Hirano, T.2    Yamasaki, H.3    Tsuji, M.4    Tsuda, H.5
  • 75
    • 84948076142 scopus 로고    scopus 로고
    • Elevated serum adenosine deaminase levels in secondary hemophagocytic lymphohistiocytosis
    • Chen W, Zhang S, Zhang W, et al. Elevated serum adenosine deaminase levels in secondary hemophagocytic lymphohistiocytosis. Int J Lab Hematol. 2015;37(4):544-550.
    • (2015) Int J Lab Hematol , vol.37 , Issue.4 , pp. 544-550
    • Chen, W.1    Zhang, S.2    Zhang, W.3
  • 76
    • 77953584060 scopus 로고    scopus 로고
    • Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis
    • Chung HJ, Park CJ, Lim JH, et al. Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis. Int J Lab Hematol. 2010;32(2):239-247.
    • (2010) Int J Lab Hematol , vol.32 , Issue.2 , pp. 239-247
    • Chung, H.J.1    Park, C.J.2    Lim, J.H.3
  • 77
    • 23744508870 scopus 로고    scopus 로고
    • Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8
    • Grossman WJ, Radhi M, Schauer D, Gerday E, Grose C, Goldman FD. Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8. Blood. 2005;106(4):1203-1206.
    • (2005) Blood , vol.106 , Issue.4 , pp. 1203-1206
    • Grossman, W.J.1    Radhi, M.2    Schauer, D.3    Gerday, E.4    Grose, C.5    Goldman, F.D.6
  • 78
    • 84973169237 scopus 로고    scopus 로고
    • Adult onset hemophagocytic lymphohistiocytosis prognosis is affected by underlying disease and coexisting viral infection: Analysis of a single institution series of 35 patients
    • published online ahead of print 3 June 2016
    • Cattaneo C, Oberti M, Skert C, et al. Adult onset hemophagocytic lymphohistiocytosis prognosis is affected by underlying disease and coexisting viral infection: analysis of a single institution series of 35 patients [published online ahead of print 3 June 2016]. Hematol Oncol. doi:10.1002/hon.2314.
    • Hematol Oncol
    • Cattaneo, C.1    Oberti, M.2    Skert, C.3
  • 79
    • 33847607365 scopus 로고    scopus 로고
    • Fatal hemophagocytic syndrome related to active human herpesvirus-8/Kaposi sarcoma-associated herpesvirus infection in human immunodeficiency virus-negative, non-transplant patients without related malignancies
    • Re A, Facchetti F, Borlenghi E, et al. Fatal hemophagocytic syndrome related to active human herpesvirus-8/Kaposi sarcoma-associated herpesvirus infection in human immunodeficiency virus-negative, non-transplant patients without related malignancies. Eur J Haematol. 2007;78(4):361-364.
    • (2007) Eur J Haematol , vol.78 , Issue.4 , pp. 361-364
    • Re, A.1    Facchetti, F.2    Borlenghi, E.3
  • 80
    • 85073079366 scopus 로고    scopus 로고
    • Genetic analysis of B-cell lymphomas associated with hemophagocytic lymphohistiocytosis
    • Patel K, Lee SS, Valasareddy P, Vontela NR, Prouet P, Martin MG. Genetic analysis of B-cell lymphomas associated with hemophagocytic lymphohistiocytosis. Blood Adv. 2016;1:205-207.
    • (2016) Blood Adv , vol.1 , pp. 205-207
    • Patel, K.1    Lee, S.S.2    Valasareddy, P.3    Vontela, N.R.4    Prouet, P.5    Martin, M.G.6
  • 81
    • 84915731934 scopus 로고    scopus 로고
    • Prognostic factors of early death in a cohort of 162 adult haemophagocytic syndrome: Impact of triggering disease and early treatment with etoposide
    • Arca M, Fardet L, Galicier L, et al. Prognostic factors of early death in a cohort of 162 adult haemophagocytic syndrome: impact of triggering disease and early treatment with etoposide. Br J Haematol. 2015;168(1):63-68.
    • (2015) Br J Haematol , vol.168 , Issue.1 , pp. 63-68
    • Arca, M.1    Fardet, L.2    Galicier, L.3
  • 82
    • 84899943272 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: Clinical analysis of 103 adult patients
    • Li J, Wang Q, Zheng W, et al. Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients. Medicine (Baltimore). 2014;93(2):100-105.
    • (2014) Medicine (Baltimore) , vol.93 , Issue.2 , pp. 100-105
    • Li, J.1    Wang, Q.2    Zheng, W.3
  • 83
    • 84923083822 scopus 로고    scopus 로고
    • Clinical characteristics, prognostic factors, and outcomes of adult patients with hemophagocytic lymphohistiocytosis
    • Otrock ZK, Eby CS. Clinical characteristics, prognostic factors, and outcomes of adult patients with hemophagocytic lymphohistiocytosis. Am J Hematol. 2015;90(3):220-224.
    • (2015) Am J Hematol , vol.90 , Issue.3 , pp. 220-224
    • Otrock, Z.K.1    Eby, C.S.2
  • 84
    • 84901690658 scopus 로고    scopus 로고
    • Risk factor analysis of non-Hodgkin lymphoma-associated haemophagocytic syndromes: A multicentre study
    • Sano H, Kobayashi R, Tanaka J, et al. Risk factor analysis of non-Hodgkin lymphoma-associated haemophagocytic syndromes: a multicentre study. Br J Haematol. 2014;165(6):786-792.
    • (2014) Br J Haematol , vol.165 , Issue.6 , pp. 786-792
    • Sano, H.1    Kobayashi, R.2    Tanaka, J.3
  • 85
    • 84891071036 scopus 로고    scopus 로고
    • Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis
    • Johnson TS, Terrell CE, Millen SH, Katz JD, Hildeman DA, Jordan MB. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014;192(1):84-91.
    • (2014) J Immunol , vol.192 , Issue.1 , pp. 84-91
    • Johnson, T.S.1    Terrell, C.E.2    Millen, S.H.3    Katz, J.D.4    Hildeman, D.A.5    Jordan, M.B.6
  • 86
    • 0036786375 scopus 로고    scopus 로고
    • Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
    • Histocyte Society
    • Henter J-I, Samuelsson-Horne A, Aricò M, et al; Histocyte Society. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002;100(7):2367-2373.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2367-2373
    • Henter, J.-I.1    Samuelsson-Horne, A.2    Aricò, M.3
  • 87
    • 80055079785 scopus 로고    scopus 로고
    • Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: Long-term results of the HLH-94 treatment protocol
    • Histiocyte Society
    • Trottestam H, Horne A, Aricò M, et al; Histiocyte Society. Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol. Blood. 2011;118(17):4577-4584.
    • (2011) Blood , vol.118 , Issue.17 , pp. 4577-4584
    • Trottestam, H.1    Horne, A.2    Aricò, M.3
  • 88
    • 0022650751 scopus 로고
    • Allogeneic bone marrow transplantation for erythrophagocytic lymphohistiocytosis
    • Fischer A, Cerf-Bensussan N, Blanche S, et al. Allogeneic bone marrow transplantation for erythrophagocytic lymphohistiocytosis. J Pediatr. 1986; 108(2):267-270.
    • (1986) J Pediatr , vol.108 , Issue.2 , pp. 267-270
    • Fischer, A.1    Cerf-Bensussan, N.2    Blanche, S.3
  • 89
    • 77954244065 scopus 로고    scopus 로고
    • Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis
    • Strout MP, Seropian S, Berliner N. Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis. Nat Rev Clin Oncol. 2010;7(7):415-420.
    • (2010) Nat Rev Clin Oncol , vol.7 , Issue.7 , pp. 415-420
    • Strout, M.P.1    Seropian, S.2    Berliner, N.3
  • 91
    • 0035873797 scopus 로고    scopus 로고
    • Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
    • Imashuku S, Kuriyama K, Teramura T, et al. Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. J Clin Oncol. 2001;19(10):2665-2673.
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2665-2673
    • Imashuku, S.1    Kuriyama, K.2    Teramura, T.3
  • 92
    • 84955578015 scopus 로고    scopus 로고
    • Comorbidities drive outcomes for both malignancy-associated and non-malignancy-associated hemophagocytic syndrome
    • Johnson B, Giri S, Nunnery SE, et al. Comorbidities drive outcomes for both malignancy-associated and non-malignancy-associated hemophagocytic syndrome. Clin Lymphoma Myeloma Leuk. 2016;16(4):230-236.
    • (2016) Clin Lymphoma Myeloma Leuk , vol.16 , Issue.4 , pp. 230-236
    • Johnson, B.1    Giri, S.2    Nunnery, S.E.3
  • 93
    • 84885636323 scopus 로고    scopus 로고
    • Lymphoma-associated hemophagocytic lymphohistiocytosis: Experience in adults from a single institution
    • Yu J-T, Wang C-Y, Yang Y, et al. Lymphoma-associated hemophagocytic lymphohistiocytosis: experience in adults from a single institution. Ann Hematol. 2013;92(11):1529-1536.
    • (2013) Ann Hematol , vol.92 , Issue.11 , pp. 1529-1536
    • Yu, J.-T.1    Wang, C.-Y.2    Yang, Y.3
  • 94
    • 34548384442 scopus 로고    scopus 로고
    • Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: A single-center retrospective report of 38 patients
    • Mahlaoui N, Ouachée-Chardin M, de Saint Basile G, et al. Immunotherapy of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins: a single-center retrospective report of 38 patients. Pediatrics. 2007;120(3):e622-e628.
    • (2007) Pediatrics , vol.120 , Issue.3 , pp. e622-e628
    • Mahlaoui, N.1    Ouachée-Chardin, M.2    de Saint Basile, G.3
  • 95
    • 51449098773 scopus 로고    scopus 로고
    • Successful use of the anti-CD25 antibody daclizumab in an adult patient with hemophagocytic lymphohistiocytosis
    • Olin RL, Nichols KE, Naghashpour M, et al. Successful use of the anti-CD25 antibody daclizumab in an adult patient with hemophagocytic lymphohistiocytosis. Am J Hematol. 2008;83(9):747-749.
    • (2008) Am J Hematol , vol.83 , Issue.9 , pp. 747-749
    • Olin, R.L.1    Nichols, K.E.2    Naghashpour, M.3
  • 96
    • 84870166438 scopus 로고    scopus 로고
    • Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab
    • Marsh RA, Allen CE, McClain KL, et al. Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab. Pediatr Blood Cancer. 2013;60(1):101-109.
    • (2013) Pediatr Blood Cancer , vol.60 , Issue.1 , pp. 101-109
    • Marsh, R.A.1    Allen, C.E.2    McClain, K.L.3
  • 97
    • 30444454994 scopus 로고    scopus 로고
    • Success with infliximab in treating refractory hemophagocytic lymphohistiocytosis
    • Henzan T, Nagafuji K, Tsukamoto H, et al. Success with infliximab in treating refractory hemophagocytic lymphohistiocytosis. Am J Hematol. 2006;81(1):59-61.
    • (2006) Am J Hematol , vol.81 , Issue.1 , pp. 59-61
    • Henzan, T.1    Nagafuji, K.2    Tsukamoto, H.3
  • 98
    • 84858247117 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in a rheumatoid arthritis patient treated with infliximab
    • Oda Y, Urushidani Y, Ooi S, et al. Hemophagocytic lymphohistiocytosis in a rheumatoid arthritis patient treated with infliximab. Intern Med. 2012;51(6):655-657.
    • (2012) Intern Med , vol.51 , Issue.6 , pp. 655-657
    • Oda, Y.1    Urushidani, Y.2    Ooi, S.3
  • 99
    • 84992734306 scopus 로고    scopus 로고
    • A retrospective analysis of 56 children with hemophagocytic lymphohistiocytosis
    • Wang Y-R, Qiu Y-N, Bai Y, Wang X-F. A retrospective analysis of 56 children with hemophagocytic lymphohistiocytosis. J Blood Med. 2016;7:227-231.
    • (2016) J Blood Med , vol.7 , pp. 227-231
    • Wang, Y.-R.1    Qiu, Y.-N.2    Bai, Y.3    Wang, X.-F.4
  • 100
    • 84999885251 scopus 로고    scopus 로고
    • Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: A retrospective multicenter study
    • Xu X-J, Wang H-S, Ju X-L, et al; Histiocytosis Study Group of the Chinese Pediatric Society. Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: a retrospective multicenter study. Pediatr Blood Cancer. 2017;64(4):e26264.
    • (2017) Pediatr Blood Cancer , vol.64 , Issue.4 , pp. e26264
    • Xu, X.-J.1    Wang, H.-S.2    Ju, X.-L.3
  • 101
    • 84937711821 scopus 로고    scopus 로고
    • Prognostic factors and long-term outcome in 52 Turkish children with hemophagocytic lymphohistiocytosis
    • Kaya Z, Bay A, Albayrak M, Kocak U, Yenicesu I, Gursel T. Prognostic factors and long-term outcome in 52 Turkish children with hemophagocytic lymphohistiocytosis. Pediatr Crit Care Med. 2015;16(6):e165-e173.
    • (2015) Pediatr Crit Care Med , vol.16 , Issue.6 , pp. e165-e173
    • Kaya, Z.1    Bay, A.2    Albayrak, M.3    Kocak, U.4    Yenicesu, I.5    Gursel, T.6
  • 102
    • 84938942078 scopus 로고    scopus 로고
    • Clinical features, genetics, and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in Korea: Report of a nationwide survey from Korea Histiocytosis Working Party
    • Koh KN, Im HJ, Chung NG, et al; Korea Histiocytosis Working Party. Clinical features, genetics, and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in Korea: report of a nationwide survey from Korea Histiocytosis Working Party. Eur J Haematol. 2015;94(1):51-59.
    • (2015) Eur J Haematol , vol.94 , Issue.1 , pp. 51-59
    • Koh, K.N.1    Im, H.J.2    Chung, N.G.3
  • 103
    • 84979009487 scopus 로고    scopus 로고
    • The use of ferritin to identify critically ill patients with secondary hemophagocytic lymphohistiocytosis
    • Grangé S, Buchonnet G, Besnier E, et al. The use of ferritin to identify critically ill patients with secondary hemophagocytic lymphohistiocytosis. Crit Care Med. 2016;44(11):e1045-e1053.
    • (2016) Crit Care Med , vol.44 , Issue.11 , pp. e1045-e1053
    • Grangé, S.1    Buchonnet, G.2    Besnier, E.3
  • 104
    • 84974801184 scopus 로고    scopus 로고
    • Prognostic factors of early outcome in pediatric hemophagocytic lymphohistiocytosis: An analysis of 116 cases
    • Bin Q, Gao J-H, Luo J-M. Prognostic factors of early outcome in pediatric hemophagocytic lymphohistiocytosis: an analysis of 116 cases. Ann Hematol. 2016;95(9):1411-1418.
    • (2016) Ann Hematol , vol.95 , Issue.9 , pp. 1411-1418
    • Bin, Q.1    Gao, J.-H.2    Luo, J.-M.3
  • 105
    • 84971384457 scopus 로고    scopus 로고
    • The prognostic significance of Beta2 microglobulin in patients with hemophagocytic lymphohistiocytosis
    • Jiang T, Ding X, Lu W. The prognostic significance of Beta2 microglobulin in patients with hemophagocytic lymphohistiocytosis. Dis Markers. 2016;2016:1523959.
    • (2016) Dis Markers , vol.2016 , pp. 1523959
    • Jiang, T.1    Ding, X.2    Lu, W.3
  • 106
    • 84937512214 scopus 로고    scopus 로고
    • Abnormalities of the lymphocyte subsets and their immunophenotype, and their prognostic significance in adult patients with hemophagocytic lymphohistiocytosis
    • Dalal BI, Vakil AP, Khare NS, Wang SY, Richards MJ, Chen LY. Abnormalities of the lymphocyte subsets and their immunophenotype, and their prognostic significance in adult patients with hemophagocytic lymphohistiocytosis. Ann Hematol. 2015;94(7):1111-1117.
    • (2015) Ann Hematol , vol.94 , Issue.7 , pp. 1111-1117
    • Dalal, B.I.1    Vakil, A.P.2    Khare, N.S.3    Wang, S.Y.4    Richards, M.J.5    Chen, L.Y.6
  • 107
    • 84873045877 scopus 로고    scopus 로고
    • Clinical features and outcome analysis of 83 childhood Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with HLH-2004 protocol [in Chinese]
    • Xiao L, Xian Y, Dai BT, et al. Clinical features and outcome analysis of 83 childhood Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis with HLH-2004 protocol [in Chinese]. Zhonghua Xue Ye Xue Za Zhi. 2011;32(10):668-672.
    • (2011) Zhonghua Xue Ye Xue Za Zhi , vol.32 , Issue.10 , pp. 668-672
    • Xiao, L.1    Xian, Y.2    Dai, B.T.3
  • 108
    • 84861131004 scopus 로고    scopus 로고
    • Analysis of prognostic risk factors in childhood hemophagocytic syndrome [in Chinese]
    • Li YG, Mao YN, Liu W, et al. Analysis of prognostic risk factors in childhood hemophagocytic syndrome [in Chinese]. Zhonghua Xue Ye Xue Za Zhi. 2011; 32(12):836-839.
    • (2011) Zhonghua Xue Ye Xue Za Zhi , vol.32 , Issue.12 , pp. 836-839
    • Li, Y.G.1    Mao, Y.N.2    Liu, W.3
  • 109
    • 72649096727 scopus 로고    scopus 로고
    • Comprehensive analyses and characterization of haemophagocytic lymphohistiocytosis in Vietnamese children
    • My LT, Lien B, Hsieh W-C, et al. Comprehensive analyses and characterization of haemophagocytic lymphohistiocytosis in Vietnamese children. Br J Haematol. 2010;148(2):301-310.
    • (2010) Br J Haematol , vol.148 , Issue.2 , pp. 301-310
    • My, L.T.1    Lien, B.2    Hsieh, W.-C.3
  • 110
    • 84886289791 scopus 로고    scopus 로고
    • Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosis
    • Jenkins RW, Clarke CJ, Lucas JT Jr, et al. Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosis. Am J Hematol. 2013;88(11):E265-E272.
    • (2013) Am J Hematol , vol.88 , Issue.11 , pp. E265-E272
    • Jenkins, R.W.1    Clarke, C.J.2    Lucas, J.T.3
  • 111
    • 84944146486 scopus 로고    scopus 로고
    • Analysis of prognostic risk factors in children with Epstein-Barr virus-associated hemophagocytic syndrome
    • Xue H, Chen C, Li W, et al. Analysis of prognostic risk factors in children with Epstein-Barr virus-associated hemophagocytic syndrome. Minerva Pediatr. 2015;67(3):251-261.
    • (2015) Minerva Pediatr , vol.67 , Issue.3 , pp. 251-261
    • Xue, H.1    Chen, C.2    Li, W.3
  • 112
    • 84977080739 scopus 로고    scopus 로고
    • The role of (18)F-FDG PET/CT in the management of patients with secondary haemophagocytic lymphohistiocytosis
    • Zheng Y, Hu G, Liu Y, et al. The role of (18)F-FDG PET/CT in the management of patients with secondary haemophagocytic lymphohistiocytosis. Clin Radiol. 2016;71(12):1248-1254.
    • (2016) Clin Radiol , vol.71 , Issue.12 , pp. 1248-1254
    • Zheng, Y.1    Hu, G.2    Liu, Y.3
  • 113
    • 77955813586 scopus 로고    scopus 로고
    • The outcome of hematopoietic stem cell transplantation in Korean children with hemophagocytic lymphohistiocytosis
    • Yoon HS, Im HJ, Moon HN, et al. The outcome of hematopoietic stem cell transplantation in Korean children with hemophagocytic lymphohistiocytosis. Pediatr Transplant. 2010;14(6):735-740.
    • (2010) Pediatr Transplant , vol.14 , Issue.6 , pp. 735-740
    • Yoon, H.S.1    Im, H.J.2    Moon, H.N.3
  • 114
    • 84948947480 scopus 로고    scopus 로고
    • Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis
    • Wang Y, Huang W, Hu L, et al. Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis. Blood. 2015;126(19):2186-2192.
    • (2015) Blood , vol.126 , Issue.19 , pp. 2186-2192
    • Wang, Y.1    Huang, W.2    Hu, L.3
  • 115
    • 84930333843 scopus 로고    scopus 로고
    • Splenectomy as a treatment for adults with relapsed hemophagocytic lymphohistiocytosis of unknown cause
    • Jing-Shi W, Yi-Ni W, Lin W, Zhao W. Splenectomy as a treatment for adults with relapsed hemophagocytic lymphohistiocytosis of unknown cause. Ann Hematol. 2015;94(5):753-760.
    • (2015) Ann Hematol , vol.94 , Issue.5 , pp. 753-760
    • Jing-Shi, W.1    Yi-Ni, W.2    Lin, W.3    Zhao, W.4
  • 116
    • 84933529009 scopus 로고    scopus 로고
    • Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation
    • Zhou X, Dotti G, Krance RA, et al. Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation. Blood. 2015;125(26):4103-4113.
    • (2015) Blood , vol.125 , Issue.26 , pp. 4103-4113
    • Zhou, X.1    Dotti, G.2    Krance, R.A.3
  • 117
    • 46849090930 scopus 로고    scopus 로고
    • Treatment outcomes with CHOP chemotherapy in adult patients with hemophagocytic lymphohistiocytosis
    • Shin H-J, Chung JS, Lee J-J, et al. Treatment outcomes with CHOP chemotherapy in adult patients with hemophagocytic lymphohistiocytosis. J Korean Med Sci. 2008;23(3):439-444.
    • (2008) J Korean Med Sci , vol.23 , Issue.3 , pp. 439-444
    • Shin, H.-J.1    Chung, J.S.2    Lee, J.-J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.