메뉴 건너뛰기




Volumn 30, Issue 6, 2016, Pages 411-420

Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: A systematic scoping review

Author keywords

Adults; Hematophagic histiocytosis; Hemophagocytic lymphohistiocytosis; Hemophagocytic syndromes; Hyperferritinemia; Macrophage activation syndromes

Indexed keywords

DOXORUBICIN; ETOPOSIDE; SOLUBLE INTERLEUKIN 2 RECEPTOR; STEROID;

EID: 84969964497     PISSN: 0268960X     EISSN: 15321681     Source Type: Journal    
DOI: 10.1016/j.blre.2016.05.001     Document Type: Review
Times cited : (222)

References (91)
  • 1
    • 77957579854 scopus 로고    scopus 로고
    • Critical care management of patients with hemophagocytic lymphohistiocytosis
    • [1] Buyse, S., Teixeira, L., Galicier, L., Mariotte, E., Lemiale, V., Seguin, A., et al. Critical care management of patients with hemophagocytic lymphohistiocytosis. Intensive Care Med 36:10 (2010), 1695–1702.
    • (2010) Intensive Care Med , vol.36 , Issue.10 , pp. 1695-1702
    • Buyse, S.1    Teixeira, L.2    Galicier, L.3    Mariotte, E.4    Lemiale, V.5    Seguin, A.6
  • 2
    • 0032937350 scopus 로고    scopus 로고
    • The histiocytoses
    • [2] Jaffe, R., The histiocytoses. Clin Lab Med 19:1 (1999), 135–155.
    • (1999) Clin Lab Med , vol.19 , Issue.1 , pp. 135-155
    • Jaffe, R.1
  • 3
    • 0033520970 scopus 로고    scopus 로고
    • Perforin gene defects in familial hemophagocytic lymphohistiocytosis
    • [3] Stepp, S.E., Dufourcq-Lagelouse, R., Le Deist, F., Bhawan, S., Certain, S., Mathew, P.A., et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 286:5446 (1999), 1957–1959.
    • (1999) Science , vol.286 , Issue.5446 , pp. 1957-1959
    • Stepp, S.E.1    Dufourcq-Lagelouse, R.2    Le Deist, F.3    Bhawan, S.4    Certain, S.5    Mathew, P.A.6
  • 4
    • 33845199637 scopus 로고    scopus 로고
    • Perforin-mediated target-cell death and immune homeostasis
    • [4] Voskoboinik, I., Smyth, M.J., Trapani, J.A., Perforin-mediated target-cell death and immune homeostasis. Nat Rev Immunol 6:12 (2006), 940–952.
    • (2006) Nat Rev Immunol , vol.6 , Issue.12 , pp. 940-952
    • Voskoboinik, I.1    Smyth, M.J.2    Trapani, J.A.3
  • 5
    • 10744224641 scopus 로고    scopus 로고
    • Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
    • [5] Feldmann, J., Callebaut, I., Raposo, G., Certain, S., Bacq, D., Dumont, C., et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 115:4 (2003), 461–473.
    • (2003) Cell , vol.115 , Issue.4 , pp. 461-473
    • Feldmann, J.1    Callebaut, I.2    Raposo, G.3    Certain, S.4    Bacq, D.5    Dumont, C.6
  • 6
    • 70350500464 scopus 로고    scopus 로고
    • Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
    • [6] zur Stadt, U., Rohr, J., Seifert, W., Koch, F., Grieve, S., Pagel, J., et al. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. Am J Hum Genet 85:4 (2009), 482–492.
    • (2009) Am J Hum Genet , vol.85 , Issue.4 , pp. 482-492
    • zur Stadt, U.1    Rohr, J.2    Seifert, W.3    Koch, F.4    Grieve, S.5    Pagel, J.6
  • 7
    • 20144363940 scopus 로고    scopus 로고
    • Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
    • [7] zur Stadt, U., Schmidt, S., Kasper, B., Beutel, K., Diler, A.S., Henter, J.I., et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet 14:6 (2005), 827–834.
    • (2005) Hum Mol Genet , vol.14 , Issue.6 , pp. 827-834
    • zur Stadt, U.1    Schmidt, S.2    Kasper, B.3    Beutel, K.4    Diler, A.S.5    Henter, J.I.6
  • 8
    • 21744445236 scopus 로고    scopus 로고
    • Haemophagocytic syndromes in adults: current concepts and challenges ahead
    • [8] Emmenegger, U., Schaer, D.J., Larroche, C., Neftel, K.A., Haemophagocytic syndromes in adults: current concepts and challenges ahead. Swiss Med Wkly 135:21–22 (2005), 299–314.
    • (2005) Swiss Med Wkly , vol.135 , Issue.21-22 , pp. 299-314
    • Emmenegger, U.1    Schaer, D.J.2    Larroche, C.3    Neftel, K.A.4
  • 9
    • 34249812697 scopus 로고    scopus 로고
    • Late-onset cases of familial hemophagocytic lymphohistiocytosis with missense perforin gene mutations
    • [9] Ueda, I., Kurokawa, Y., Koike, K., Ito, S., Sakata, A., Matsumora, T., et al. Late-onset cases of familial hemophagocytic lymphohistiocytosis with missense perforin gene mutations. Am J Hematol 82:6 (2007), 427–432.
    • (2007) Am J Hematol , vol.82 , Issue.6 , pp. 427-432
    • Ueda, I.1    Kurokawa, Y.2    Koike, K.3    Ito, S.4    Sakata, A.5    Matsumora, T.6
  • 10
    • 82155184541 scopus 로고    scopus 로고
    • Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH
    • [10] Zhang, K., Jordan, M.B., Marsh, R.A., Johnson, J.A., Kissell, D., Meller, J., et al. Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. Blood 118:22 (2011), 5794–5798.
    • (2011) Blood , vol.118 , Issue.22 , pp. 5794-5798
    • Zhang, K.1    Jordan, M.B.2    Marsh, R.A.3    Johnson, J.A.4    Kissell, D.5    Meller, J.6
  • 11
    • 0037105371 scopus 로고    scopus 로고
    • Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations
    • [11] Clementi, R., Emmi, L., Maccario, R., Liotta, F., Moretta, L., Danesino, C., et al. Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations. Blood 100:6 (2002), 2266–2267.
    • (2002) Blood , vol.100 , Issue.6 , pp. 2266-2267
    • Clementi, R.1    Emmi, L.2    Maccario, R.3    Liotta, F.4    Moretta, L.5    Danesino, C.6
  • 12
    • 33845619137 scopus 로고    scopus 로고
    • HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
    • [12] Henter, J.I., Horne, A., Arico, M., Egeler, R.M., Filipovich, A.H., Imashuku, S., et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 48:2 (2007), 124–131.
    • (2007) Pediatr Blood Cancer , vol.48 , Issue.2 , pp. 124-131
    • Henter, J.I.1    Horne, A.2    Arico, M.3    Egeler, R.M.4    Filipovich, A.H.5    Imashuku, S.6
  • 13
    • 54449101721 scopus 로고    scopus 로고
    • Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases
    • [13] Fukaya, S., Yasuda, S., Hashimoto, T., Oku, K., Kataoka, H., Horita, T., et al. Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology 47:11 (2008), 1686–1691.
    • (2008) Rheumatology , vol.47 , Issue.11 , pp. 1686-1691
    • Fukaya, S.1    Yasuda, S.2    Hashimoto, T.3    Oku, K.4    Kataoka, H.5    Horita, T.6
  • 14
    • 0037018775 scopus 로고    scopus 로고
    • Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation
    • [14] Emmenegger, U., Reimers, A., Frey, U., Fux, C., Bihl, F., Semela, D., et al. Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation. Swiss Med Wkly 132:17–18 (2002), 230–236.
    • (2002) Swiss Med Wkly , vol.132 , Issue.17-18 , pp. 230-236
    • Emmenegger, U.1    Reimers, A.2    Frey, U.3    Fux, C.4    Bihl, F.5    Semela, D.6
  • 15
    • 2942597667 scopus 로고    scopus 로고
    • Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients—a postmortem clinicopathologic analysis
    • [15] Strauss, R., Neureiter, D., Westenburger, B., Wehler, M., Kirchner, T., Hahn, E.G., Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients—a postmortem clinicopathologic analysis. Crit Care Med 32:6 (2004), 1316–1321.
    • (2004) Crit Care Med , vol.32 , Issue.6 , pp. 1316-1321
    • Strauss, R.1    Neureiter, D.2    Westenburger, B.3    Wehler, M.4    Kirchner, T.5    Hahn, E.G.6
  • 16
    • 0030743537 scopus 로고    scopus 로고
    • Thrombocytopenia in the sepsis syndrome: role of hemophagocytosis and macrophage colony-stimulating factor
    • [16] Francois, B., Trimoreau, F., Vignon, P., Fixe, P., Praloran, V., Gastinne, H., Thrombocytopenia in the sepsis syndrome: role of hemophagocytosis and macrophage colony-stimulating factor. Am J Med 103:2 (1997), 114–120.
    • (1997) Am J Med , vol.103 , Issue.2 , pp. 114-120
    • Francois, B.1    Trimoreau, F.2    Vignon, P.3    Fixe, P.4    Praloran, V.5    Gastinne, H.6
  • 17
    • 84894448683 scopus 로고    scopus 로고
    • Marrow assessment for hemophagocytic lymphohistiocytosis demonstrates poor correlation with disease probability
    • [17] Ho, C., Yao, X., Tian, L., Li, F.Y., Podoltsev, N., Xu, M.L., Marrow assessment for hemophagocytic lymphohistiocytosis demonstrates poor correlation with disease probability. Am J Clin Pathol 141:1 (2014), 62–71.
    • (2014) Am J Clin Pathol , vol.141 , Issue.1 , pp. 62-71
    • Ho, C.1    Yao, X.2    Tian, L.3    Li, F.Y.4    Podoltsev, N.5    Xu, M.L.6
  • 18
    • 84907408074 scopus 로고    scopus 로고
    • Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome
    • [18] Fardet, L., Galicier, L., Lambotte, O., Marzac, C., Aumont, C., Chahwan, D., et al. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis Rheum 66:9 (2014), 2613–2620.
    • (2014) Arthritis Rheum , vol.66 , Issue.9 , pp. 2613-2620
    • Fardet, L.1    Galicier, L.2    Lambotte, O.3    Marzac, C.4    Aumont, C.5    Chahwan, D.6
  • 19
    • 84898886282 scopus 로고    scopus 로고
    • Prognostic factors and outcomes of adults with hemophagocytic lymphohistiocytosis
    • [19] Parikh, S.A., Kapoor, P., Letendre, L., Kumar, S., Wolanskyj, A.P., Prognostic factors and outcomes of adults with hemophagocytic lymphohistiocytosis. Mayo Clin Proc 89:4 (2014), 484–492.
    • (2014) Mayo Clin Proc , vol.89 , Issue.4 , pp. 484-492
    • Parikh, S.A.1    Kapoor, P.2    Letendre, L.3    Kumar, S.4    Wolanskyj, A.P.5
  • 20
    • 0031127807 scopus 로고    scopus 로고
    • Hemophagocytic syndrome (HPS) in children and adults
    • [20] Tsuda, H., Hemophagocytic syndrome (HPS) in children and adults. Int J Hematol 65:3 (1997), 215–226.
    • (1997) Int J Hematol , vol.65 , Issue.3 , pp. 215-226
    • Tsuda, H.1
  • 21
    • 84899415642 scopus 로고    scopus 로고
    • A web-based Delphi study for eliciting helpful criteria in the positive diagnosis of hemophagocytic syndrome in adult patients
    • e94024
    • [21] Hejblum, G., Lambotte, O., Galicier, L., Coppo, P., Marzac, C., Aumont, C., et al. A web-based Delphi study for eliciting helpful criteria in the positive diagnosis of hemophagocytic syndrome in adult patients. PLoS One, 9(4), 2014, e94024.
    • (2014) PLoS One , vol.9 , Issue.4
    • Hejblum, G.1    Lambotte, O.2    Galicier, L.3    Coppo, P.4    Marzac, C.5    Aumont, C.6
  • 22
    • 84941934899 scopus 로고    scopus 로고
    • Neurological involvement and characterization in acquired hemophagocytic lymphohistiocytosis in adulthood
    • [22] Gratton, S.M., Powell, T.R., Theeler, B.J., Hawley, J.S., Amjad, F.S., Tornatore, C., Neurological involvement and characterization in acquired hemophagocytic lymphohistiocytosis in adulthood. J Neurol Sci 357:1–2 (2015), 136–142.
    • (2015) J Neurol Sci , vol.357 , Issue.1-2 , pp. 136-142
    • Gratton, S.M.1    Powell, T.R.2    Theeler, B.J.3    Hawley, J.S.4    Amjad, F.S.5    Tornatore, C.6
  • 23
    • 0036786375 scopus 로고    scopus 로고
    • Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
    • [23] Henter, J.I., Samuelsson-Horne, A., Arico, M., Egeler, R.M., Elinder, G., Filipovich, A.H., et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood 100:7 (2002), 2367–2373.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2367-2373
    • Henter, J.I.1    Samuelsson-Horne, A.2    Arico, M.3    Egeler, R.M.4    Elinder, G.5    Filipovich, A.H.6
  • 25
    • 84929190350 scopus 로고    scopus 로고
    • How I treat hemophagocytic lymphohistiocytosis in the adult patient
    • [25] Schram, A.M., Berliner, N., How I treat hemophagocytic lymphohistiocytosis in the adult patient. Blood 125:19 (2015), 2908–2914.
    • (2015) Blood , vol.125 , Issue.19 , pp. 2908-2914
    • Schram, A.M.1    Berliner, N.2
  • 29
    • 42649121988 scopus 로고    scopus 로고
    • Visceral leishmaniasis associated hemophagocytic lymphohistiocytosis — case report and systematic review
    • [29] Rajagopala, S., Dutta, U., Chandra, K.S.P., Bhatia, P., Varma, N., Kochhar, R., Visceral leishmaniasis associated hemophagocytic lymphohistiocytosis — case report and systematic review. J Infect 56:5 (2008), 381–388.
    • (2008) J Infect , vol.56 , Issue.5 , pp. 381-388
    • Rajagopala, S.1    Dutta, U.2    Chandra, K.S.P.3    Bhatia, P.4    Varma, N.5    Kochhar, R.6
  • 30
    • 14644388070 scopus 로고    scopus 로고
    • Scoping studies: towards a methodological framework
    • [30] Arksey, H., O'Malley, L., Scoping studies: towards a methodological framework. Int J Soc Res Methodol 8:1 (2005), 19–32.
    • (2005) Int J Soc Res Methodol , vol.8 , Issue.1 , pp. 19-32
    • Arksey, H.1    O'Malley, L.2
  • 31
    • 84924167554 scopus 로고    scopus 로고
    • Varieties of integrative scholarship: why rules of evidence, criteria, and standards matter
    • [31] McGaghie, W.C., Varieties of integrative scholarship: why rules of evidence, criteria, and standards matter. Acad Med 90:3 (2015), 294–302.
    • (2015) Acad Med , vol.90 , Issue.3 , pp. 294-302
    • McGaghie, W.C.1
  • 32
    • 77956634456 scopus 로고    scopus 로고
    • Scoping studies: advancing the methodology
    • [32] Levac, D., Colquhoun, H., O'Brien, K.K., Scoping studies: advancing the methodology. Implement Sci 5:1 (2010), 1–9.
    • (2010) Implement Sci , vol.5 , Issue.1 , pp. 1-9
    • Levac, D.1    Colquhoun, H.2    O'Brien, K.K.3
  • 33
    • 84888127735 scopus 로고    scopus 로고
    • Recombinant human thrombopoietin is an effective treatment for thrombocytopenia in hemophagocytic lymphohistiocytosis
    • [33] Wang, Y., Wang, Z., Wu, L., Zhang, J., Wang, J., Yan, L., Recombinant human thrombopoietin is an effective treatment for thrombocytopenia in hemophagocytic lymphohistiocytosis. Ann Hematol 92:12 (2013), 1695–1699.
    • (2013) Ann Hematol , vol.92 , Issue.12 , pp. 1695-1699
    • Wang, Y.1    Wang, Z.2    Wu, L.3    Zhang, J.4    Wang, J.5    Yan, L.6
  • 34
    • 84948947480 scopus 로고    scopus 로고
    • Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis
    • [34] Wang, Y., Huang, W., Hu, L., Cen, X., Li, L., Wang, J., et al. Multicenter study of combination DEP regimen as a salvage therapy for adult refractory hemophagocytic lymphohistiocytosis. Blood 126:19 (2015), 2186–2192.
    • (2015) Blood , vol.126 , Issue.19 , pp. 2186-2192
    • Wang, Y.1    Huang, W.2    Hu, L.3    Cen, X.4    Li, L.5    Wang, J.6
  • 35
    • 0030782098 scopus 로고    scopus 로고
    • Role of hemophagocytic histiocytosis in the etiology of thrombocytopenia in patients with sepsis syndrome or septic shock
    • [35] Stephan, F., Thioliere, B., Verdy, E., Tulliez, M., Role of hemophagocytic histiocytosis in the etiology of thrombocytopenia in patients with sepsis syndrome or septic shock. Clin Infect Dis 25:5 (1997), 1159–1164.
    • (1997) Clin Infect Dis , vol.25 , Issue.5 , pp. 1159-1164
    • Stephan, F.1    Thioliere, B.2    Verdy, E.3    Tulliez, M.4
  • 36
    • 27744607629 scopus 로고    scopus 로고
    • Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome
    • [36] Mazodier, K., Marin, V., Novick, D., Farnarier, C., Robitail, S., Schleinitz, N., et al. Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood 106:10 (2005), 3483–3489.
    • (2005) Blood , vol.106 , Issue.10 , pp. 3483-3489
    • Mazodier, K.1    Marin, V.2    Novick, D.3    Farnarier, C.4    Robitail, S.5    Schleinitz, N.6
  • 37
    • 79952099330 scopus 로고    scopus 로고
    • Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection
    • [37] Beutel, G., Wiesner, O., Eder, M., Hafer, C., Schneider, A.S., Kielstein, J.T., et al. Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care, 15(2), 2011, R80.
    • (2011) Crit Care , vol.15 , Issue.2 , pp. R80
    • Beutel, G.1    Wiesner, O.2    Eder, M.3    Hafer, C.4    Schneider, A.S.5    Kielstein, J.T.6
  • 38
    • 84895750755 scopus 로고    scopus 로고
    • Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy
    • [38] Delavigne, K., Berard, E., Bertoli, S., Corre, J., Duchayne, E., Demur, C., et al. Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy. Haematologica 99:3 (2014), 474–480.
    • (2014) Haematologica , vol.99 , Issue.3 , pp. 474-480
    • Delavigne, K.1    Berard, E.2    Bertoli, S.3    Corre, J.4    Duchayne, E.5    Demur, C.6
  • 39
    • 77952895495 scopus 로고    scopus 로고
    • Reactive haemophagocytic syndrome in 58 HIV-1-infected patients: clinical features, underlying diseases and prognosis
    • [39] Fardet, L., Lambotte, O., Meynard, J.L., Kamouh, W., Galicier, L., Marzac, C., et al. Reactive haemophagocytic syndrome in 58 HIV-1-infected patients: clinical features, underlying diseases and prognosis. AIDS 24:9 (2010), 1299–1306.
    • (2010) AIDS , vol.24 , Issue.9 , pp. 1299-1306
    • Fardet, L.1    Lambotte, O.2    Meynard, J.L.3    Kamouh, W.4    Galicier, L.5    Marzac, C.6
  • 40
    • 73449140076 scopus 로고    scopus 로고
    • Early diagnostic value of low percentage of glycosylated ferritin in secondary hemophagocytic lymphohistiocytosis
    • [40] Wang, Z., Wang, Y., Wang, J., Feng, C., Tian, L., Wu, L., Early diagnostic value of low percentage of glycosylated ferritin in secondary hemophagocytic lymphohistiocytosis. Int J Hematol 90:4 (2009), 501–505.
    • (2009) Int J Hematol , vol.90 , Issue.4 , pp. 501-505
    • Wang, Z.1    Wang, Y.2    Wang, J.3    Feng, C.4    Tian, L.5    Wu, L.6
  • 41
    • 84948076142 scopus 로고    scopus 로고
    • Elevated serum adenosine deaminase levels in secondary hemophagocytic lymphohistiocytosis
    • [41] Chen, W., Zhang, S., Zhang, W., Yang, X., Xu, J., Qiu, H., et al. Elevated serum adenosine deaminase levels in secondary hemophagocytic lymphohistiocytosis. Int J Lab Hematol 37:4 (2015), 544–550.
    • (2015) Int J Lab Hematol , vol.37 , Issue.4 , pp. 544-550
    • Chen, W.1    Zhang, S.2    Zhang, W.3    Yang, X.4    Xu, J.5    Qiu, H.6
  • 42
    • 0141792696 scopus 로고    scopus 로고
    • The serum cytokine profiles of lymphoma-associated hemophagocytic syndrome: a comparative analysis of B-cell and T-cell/natural killer cell lymphomas
    • [42] Ohno, T., Ueda, Y., Nagai, K.I., Takahashi, T., Konaka, Y., Takamatsu, T., et al. The serum cytokine profiles of lymphoma-associated hemophagocytic syndrome: a comparative analysis of B-cell and T-cell/natural killer cell lymphomas. Int J Hematol 77:3 (2003), 286–294.
    • (2003) Int J Hematol , vol.77 , Issue.3 , pp. 286-294
    • Ohno, T.1    Ueda, Y.2    Nagai, K.I.3    Takahashi, T.4    Konaka, Y.5    Takamatsu, T.6
  • 43
    • 85038116749 scopus 로고    scopus 로고
    • Outcome of hematopoietic cell transplant for hemophagocytic lymphohistiocytosis in adults: a single center experience
    • [43] Chandrakasan, S., Marsh, R.A., Bellman, D., Grimley, M., Bleesing, J., Jordan, M., et al. Outcome of hematopoietic cell transplant for hemophagocytic lymphohistiocytosis in adults: a single center experience. Biol Blood Marrow Transplant, 19(2 SUPPL.1), 2013, S284.
    • (2013) Biol Blood Marrow Transplant , vol.19 , Issue.2 SUPPL.1 , pp. S284
    • Chandrakasan, S.1    Marsh, R.A.2    Bellman, D.3    Grimley, M.4    Bleesing, J.5    Jordan, M.6
  • 44
    • 85007147721 scopus 로고    scopus 로고
    • Adolescents and young adults with hemophagocytic lymphohistiocytosis who undergo allogeneic hematopoietic cell transplantation are at increased risk of mortality compared to younger patients
    • [44] Chandrakasan, S., Grimley, M., Bleesing, J., Jordan, M., Filipovich, A., Adolescents and young adults with hemophagocytic lymphohistiocytosis who undergo allogeneic hematopoietic cell transplantation are at increased risk of mortality compared to younger patients. Blood, 122(21), 2013, 2087.
    • (2013) Blood , vol.122 , Issue.21 , pp. 2087
    • Chandrakasan, S.1    Grimley, M.2    Bleesing, J.3    Jordan, M.4    Filipovich, A.5
  • 45
    • 76949093374 scopus 로고    scopus 로고
    • Frequency, clinical features and prognosis of cutaneous manifestations in adult patients with reactive haemophagocytic syndrome
    • [45] Fardet, L., Galicier, L., Vignon-Pennamen, M.D., Regnier, S., Noguera, M.E., de Labarthe, A., et al. Frequency, clinical features and prognosis of cutaneous manifestations in adult patients with reactive haemophagocytic syndrome. Br J Dermatol 162:3 (2010), 547–553.
    • (2010) Br J Dermatol , vol.162 , Issue.3 , pp. 547-553
    • Fardet, L.1    Galicier, L.2    Vignon-Pennamen, M.D.3    Regnier, S.4    Noguera, M.E.5    de Labarthe, A.6
  • 46
    • 84915731934 scopus 로고    scopus 로고
    • Prognostic factors of early death in a cohort of 162 adult haemophagocytic syndrome: impact of triggering disease and early treatment with etoposide
    • [46] Arca, M., Fardet, L., Galicier, L., Riviere, S., Marzac, C., Aumont, C., et al. Prognostic factors of early death in a cohort of 162 adult haemophagocytic syndrome: impact of triggering disease and early treatment with etoposide. Br J Haematol 168:1 (2015), 63–68.
    • (2015) Br J Haematol , vol.168 , Issue.1 , pp. 63-68
    • Arca, M.1    Fardet, L.2    Galicier, L.3    Riviere, S.4    Marzac, C.5    Aumont, C.6
  • 47
    • 84912072894 scopus 로고    scopus 로고
    • Reactive hemophagocytic syndrome in adults: a retrospective analysis of 162 patients
    • [47] Riviere, S., Galicier, L., Coppo, P., Marzac, C., Aumont, C., Lambotte, O., et al. Reactive hemophagocytic syndrome in adults: a retrospective analysis of 162 patients. Am J Med 127:11 (2014), 1118–1125.
    • (2014) Am J Med , vol.127 , Issue.11 , pp. 1118-1125
    • Riviere, S.1    Galicier, L.2    Coppo, P.3    Marzac, C.4    Aumont, C.5    Lambotte, O.6
  • 48
    • 43949133012 scopus 로고    scopus 로고
    • Low glycosylated ferritin, a good marker for the diagnosis of hemophagocytic syndrome
    • [48] Fardet, L., Coppo, P., Kettaneh, A., Dehoux, M., Cabane, J., Lambotte, O., Low glycosylated ferritin, a good marker for the diagnosis of hemophagocytic syndrome. Arthritis Rheum 58:5 (2008), 1521–1527.
    • (2008) Arthritis Rheum , vol.58 , Issue.5 , pp. 1521-1527
    • Fardet, L.1    Coppo, P.2    Kettaneh, A.3    Dehoux, M.4    Cabane, J.5    Lambotte, O.6
  • 50
    • 34547633673 scopus 로고    scopus 로고
    • Nationwide survey of hemophagocytic lymphohistiocytosis in Japan
    • [50] Ishii, E., Ohga, S., Imashuku, S., Yasukawa, M., Tsuda, H., Miura, I., et al. Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol 86:1 (2007), 58–65.
    • (2007) Int J Hematol , vol.86 , Issue.1 , pp. 58-65
    • Ishii, E.1    Ohga, S.2    Imashuku, S.3    Yasukawa, M.4    Tsuda, H.5    Miura, I.6
  • 51
    • 79953220496 scopus 로고    scopus 로고
    • Malignancy-associated hemophagocytic lymphohistiocytosis in adults: a retrospective population-based analysis from a single center
    • [51] Machaczka, M., Vaktnas, J., Klimkowska, M., Hagglund, H., Malignancy-associated hemophagocytic lymphohistiocytosis in adults: a retrospective population-based analysis from a single center. Leuk Lymphoma 52:4 (2011), 613–619.
    • (2011) Leuk Lymphoma , vol.52 , Issue.4 , pp. 613-619
    • Machaczka, M.1    Vaktnas, J.2    Klimkowska, M.3    Hagglund, H.4
  • 52
    • 0026065540 scopus 로고
    • Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society
    • [52] Henter, J.I., Elinder, G., Ost, A., Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Semin Oncol 18:1 (1991), 29–33.
    • (1991) Semin Oncol , vol.18 , Issue.1 , pp. 29-33
    • Henter, J.I.1    Elinder, G.2    Ost, A.3
  • 53
    • 0028177849 scopus 로고
    • Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults
    • [53] Akashi, K., Hayashi, S., Gondo, H., Mizuno, S.I., Harada, M., Tamura, K., et al. Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults. Br J Haematol 87:2 (1994), 243–250.
    • (1994) Br J Haematol , vol.87 , Issue.2 , pp. 243-250
    • Akashi, K.1    Hayashi, S.2    Gondo, H.3    Mizuno, S.I.4    Harada, M.5    Tamura, K.6
  • 55
    • 0038714753 scopus 로고    scopus 로고
    • Treatment of Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) in young adults: a report from the HLH study center
    • [55] Imashuku, S., Kuriyama, K., Sakai, R., Nakao, Y., Masuda, S., Yasuda, N., et al. Treatment of Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) in young adults: a report from the HLH study center. Med Pediatr Oncol 41:2 (2003), 103–109.
    • (2003) Med Pediatr Oncol , vol.41 , Issue.2 , pp. 103-109
    • Imashuku, S.1    Kuriyama, K.2    Sakai, R.3    Nakao, Y.4    Masuda, S.5    Yasuda, N.6
  • 56
    • 84868624308 scopus 로고    scopus 로고
    • Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis
    • [56] Kuriyama, T., Takenaka, K., Kohno, K., Yamauchi, T., Daitoku, S., Yoshimoto, G., et al. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis. Blood 120:19 (2012), 4058–4067.
    • (2012) Blood , vol.120 , Issue.19 , pp. 4058-4067
    • Kuriyama, T.1    Takenaka, K.2    Kohno, K.3    Yamauchi, T.4    Daitoku, S.5    Yoshimoto, G.6
  • 57
    • 84866087810 scopus 로고    scopus 로고
    • Familial hemophagocytic lymphohistiocytosis may present during adulthood: clinical and genetic features of a small series
    • e44649
    • [57] Sieni, E., Cetica, V., Piccin, A., Gherlinzoni, F., Sasso, F.C., Rabusin, M., et al. Familial hemophagocytic lymphohistiocytosis may present during adulthood: clinical and genetic features of a small series. PLoS One, 7(9), 2012, e44649.
    • (2012) PLoS One , vol.7 , Issue.9
    • Sieni, E.1    Cetica, V.2    Piccin, A.3    Gherlinzoni, F.4    Sasso, F.C.5    Rabusin, M.6
  • 58
    • 84923083822 scopus 로고    scopus 로고
    • Clinical characteristics, prognostic factors, and outcomes of adult patients with hemophagocytic lymphohistiocytosis
    • [58] Otrock, Z.K., Eby, C.S., Clinical characteristics, prognostic factors, and outcomes of adult patients with hemophagocytic lymphohistiocytosis. Am J Hematol 90:3 (2015), 220–224.
    • (2015) Am J Hematol , vol.90 , Issue.3 , pp. 220-224
    • Otrock, Z.K.1    Eby, C.S.2
  • 59
    • 84937890416 scopus 로고    scopus 로고
    • Ehrlichia-induced hemophagocytic lymphohistiocytosis: a case series and review of literature
    • [59] Otrock, Z.K., Gonzalez, M.D., Eby, C.S., Ehrlichia-induced hemophagocytic lymphohistiocytosis: a case series and review of literature. Blood Cells Mol Dis 55:3 (2015), 191–193.
    • (2015) Blood Cells Mol Dis , vol.55 , Issue.3 , pp. 191-193
    • Otrock, Z.K.1    Gonzalez, M.D.2    Eby, C.S.3
  • 60
    • 84879914829 scopus 로고    scopus 로고
    • Clinical features and perforin A91V gene analysis in 31 patients with macrophage activation syndrome and systemic juvenile idiopathic arthritis in China
    • [60] Huasong, Z., Ping, W., Xiangyuan, C., Yandan, W., Clinical features and perforin A91V gene analysis in 31 patients with macrophage activation syndrome and systemic juvenile idiopathic arthritis in China. J Rheumatol 40:7 (2013), 1238–1239.
    • (2013) J Rheumatol , vol.40 , Issue.7 , pp. 1238-1239
    • Huasong, Z.1    Ping, W.2    Xiangyuan, C.3    Yandan, W.4
  • 61
    • 84930333843 scopus 로고    scopus 로고
    • Splenectomy as a treatment for adults with relapsed hemophagocytic lymphohistiocytosis of unknown cause
    • [61] Jing-Shi, W., Yi-Ni, W., Lin, W., Zhao, W., Splenectomy as a treatment for adults with relapsed hemophagocytic lymphohistiocytosis of unknown cause. Ann Hematol 94:5 (2015), 753–760.
    • (2015) Ann Hematol , vol.94 , Issue.5 , pp. 753-760
    • Jing-Shi, W.1    Yi-Ni, W.2    Lin, W.3    Zhao, W.4
  • 62
    • 84907210985 scopus 로고    scopus 로고
    • Genetic features of late onset primary hemophagocytic lymphohistiocytosis in adolescence or adulthood
    • e107386
    • [62] Wang, Y., Wang, Z., Zhang, J., Wei, Q., Tang, R., Qi, J., et al. Genetic features of late onset primary hemophagocytic lymphohistiocytosis in adolescence or adulthood. PLoS One, 9(9), 2014, e107386.
    • (2014) PLoS One , vol.9 , Issue.9
    • Wang, Y.1    Wang, Z.2    Zhang, J.3    Wei, Q.4    Tang, R.5    Qi, J.6
  • 63
    • 84898872294 scopus 로고    scopus 로고
    • A high sIL-2R/ferritin ratio is a useful marker for the diagnosis of lymphoma-associated hemophagocytic syndrome
    • [63] Tsuji, T., Hirano, T., Yamasaki, H., Tsuji, M., Tsuda, H., A high sIL-2R/ferritin ratio is a useful marker for the diagnosis of lymphoma-associated hemophagocytic syndrome. Ann Hematol 93:5 (2014), 821–826.
    • (2014) Ann Hematol , vol.93 , Issue.5 , pp. 821-826
    • Tsuji, T.1    Hirano, T.2    Yamasaki, H.3    Tsuji, M.4    Tsuda, H.5
  • 64
    • 84925013807 scopus 로고    scopus 로고
    • Marked hyperferritinemia does not predict for HLH in the adult population
    • [64] Schram, A.M., Campigotto, F., Mullally, A., Fogerty, A., Massarotti, E., Neuberg, D., et al. Marked hyperferritinemia does not predict for HLH in the adult population. Blood 125:10 (2015), 1548–1552.
    • (2015) Blood , vol.125 , Issue.10 , pp. 1548-1552
    • Schram, A.M.1    Campigotto, F.2    Mullally, A.3    Fogerty, A.4    Massarotti, E.5    Neuberg, D.6
  • 65
    • 84862682684 scopus 로고    scopus 로고
    • Clinical features of adult patients with secondary hemophagocytic lymphohistiocytosis from causes other than lymphoma: an analysis of treatment outcome and prognostic factors
    • [65] Park, H.S., Kim, D.Y., Lee, J.H., Kim, S.D., Park, Y.H., Lee, J.S., et al. Clinical features of adult patients with secondary hemophagocytic lymphohistiocytosis from causes other than lymphoma: an analysis of treatment outcome and prognostic factors. Ann Hematol 91:6 (2012), 897–904.
    • (2012) Ann Hematol , vol.91 , Issue.6 , pp. 897-904
    • Park, H.S.1    Kim, D.Y.2    Lee, J.H.3    Kim, S.D.4    Park, Y.H.5    Lee, J.S.6
  • 66
    • 0031214735 scopus 로고    scopus 로고
    • Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment
    • [66] Imashuku, S., Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment. Int J Hematol 66:2 (1997), 135–151.
    • (1997) Int J Hematol , vol.66 , Issue.2 , pp. 135-151
    • Imashuku, S.1
  • 67
    • 0034907097 scopus 로고    scopus 로고
    • Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes
    • [67] Emmenegger, U., Frey, U., Reimers, A., Fux, C., Semela, D., Cottagnoud, P., et al. Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes. Am J Hematol 68:1 (2001), 4–10.
    • (2001) Am J Hematol , vol.68 , Issue.1 , pp. 4-10
    • Emmenegger, U.1    Frey, U.2    Reimers, A.3    Fux, C.4    Semela, D.5    Cottagnoud, P.6
  • 68
    • 70350461711 scopus 로고    scopus 로고
    • High incidence of haemophagocytic syndrome following umbilical cord blood transplantation for adults
    • [68] Takagi, S., Masuoka, K., Uchida, N., Ishiwata, K., Araoka, H., Tsuji, M., et al. High incidence of haemophagocytic syndrome following umbilical cord blood transplantation for adults. Br J Haematol 147:4 (2009), 543–553.
    • (2009) Br J Haematol , vol.147 , Issue.4 , pp. 543-553
    • Takagi, S.1    Masuoka, K.2    Uchida, N.3    Ishiwata, K.4    Araoka, H.5    Tsuji, M.6
  • 69
    • 84937512214 scopus 로고    scopus 로고
    • Abnormalities of the lymphocyte subsets and their immunophenotype, and their prognostic significance in adult patients with hemophagocytic lymphohistiocytosis
    • [69] Dalal, B.I., Vakil, A.P., Khare, N.S., Wang, S.Y., Richards, M.J., Chen, L.Y., Abnormalities of the lymphocyte subsets and their immunophenotype, and their prognostic significance in adult patients with hemophagocytic lymphohistiocytosis. Ann Hematol 94:7 (2015), 1111–1117.
    • (2015) Ann Hematol , vol.94 , Issue.7 , pp. 1111-1117
    • Dalal, B.I.1    Vakil, A.P.2    Khare, N.S.3    Wang, S.Y.4    Richards, M.J.5    Chen, L.Y.6
  • 70
    • 46849090930 scopus 로고    scopus 로고
    • Treatment outcomes with CHOP chemotherapy in adult patients with hemophagocytic lymphohistiocytosis
    • [70] Shin, H.J., Joo, S.C., Lee, J.J., Sang, K.S., Young, J.C., Kim, Y.K., et al. Treatment outcomes with CHOP chemotherapy in adult patients with hemophagocytic lymphohistiocytosis. J Korean Med Sci 23:3 (2008), 439–444.
    • (2008) J Korean Med Sci , vol.23 , Issue.3 , pp. 439-444
    • Shin, H.J.1    Joo, S.C.2    Lee, J.J.3    Sang, K.S.4    Young, J.C.5    Kim, Y.K.6
  • 71
    • 17444452668 scopus 로고    scopus 로고
    • A clinical analysis of 52 adult patients with hemophagocytic syndrome: the prognostic significance of the underlying diseases
    • [71] Takahashi, N., Chubachi, A., Kume, M., Hatano, Y., Komatsuda, A., Kawabata, Y., et al. A clinical analysis of 52 adult patients with hemophagocytic syndrome: the prognostic significance of the underlying diseases. Int J Hematol 74:2 (2001), 209–213.
    • (2001) Int J Hematol , vol.74 , Issue.2 , pp. 209-213
    • Takahashi, N.1    Chubachi, A.2    Kume, M.3    Hatano, Y.4    Komatsuda, A.5    Kawabata, Y.6
  • 72
    • 0035873797 scopus 로고    scopus 로고
    • Requirement for etoposide in the treatment of Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis
    • [72] Imashuku, S., Kuriyama, K., Teramura, T., Ishii, E., Kinugawa, N., Kato, M., et al. Requirement for etoposide in the treatment of Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis. J Clin Oncol 19:10 (2001), 2665–2673.
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2665-2673
    • Imashuku, S.1    Kuriyama, K.2    Teramura, T.3    Ishii, E.4    Kinugawa, N.5    Kato, M.6
  • 73
    • 84899943272 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients
    • [73] Li, J., Wang, Q., Zheng, W., Ma, J., Zhang, W., Wang, W., et al. Hemophagocytic lymphohistiocytosis: clinical analysis of 103 adult patients. Medicine 93:2 (2014), 100–105.
    • (2014) Medicine , vol.93 , Issue.2 , pp. 100-105
    • Li, J.1    Wang, Q.2    Zheng, W.3    Ma, J.4    Zhang, W.5    Wang, W.6
  • 74
    • 84875112351 scopus 로고    scopus 로고
    • A clinicopathological analysis of 26 patients with infection-associated haemophagocytic lymphohistiocytosis and the importance of bone marrow phagocytosis for the early initiation of immunomodulatory treatment
    • [74] Nair, V., Das, S., Sharma, A., Sharma, S., Sharma, P., Ray, S., et al. A clinicopathological analysis of 26 patients with infection-associated haemophagocytic lymphohistiocytosis and the importance of bone marrow phagocytosis for the early initiation of immunomodulatory treatment. Postgrad Med J 89:1050 (2012), 185–192.
    • (2012) Postgrad Med J , vol.89 , Issue.1050 , pp. 185-192
    • Nair, V.1    Das, S.2    Sharma, A.3    Sharma, S.4    Sharma, P.5    Ray, S.6
  • 75
    • 84859920093 scopus 로고    scopus 로고
    • When should hemodialysis or plasma exchange be used to reduce early death in hemophagocytic lymphohistiocytosis?
    • [75] He, A., Zhang, W., Niu, Y., Wang, J., Chao, X., Yang, Y., When should hemodialysis or plasma exchange be used to reduce early death in hemophagocytic lymphohistiocytosis?. Int Med J 19:1 (2012), 27–30.
    • (2012) Int Med J , vol.19 , Issue.1 , pp. 27-30
    • He, A.1    Zhang, W.2    Niu, Y.3    Wang, J.4    Chao, X.5    Yang, Y.6
  • 76
    • 84895083284 scopus 로고    scopus 로고
    • Identification of clinical features of lymphoma-associated hemophagocytic syndrome (LAHS): an analysis of 69 patients with hemophagocytic syndrome from a single-center in central region of China
    • [76] Li, F., Li, P., Zhang, R., Yang, G., Ji, D., Huang, X., et al. Identification of clinical features of lymphoma-associated hemophagocytic syndrome (LAHS): an analysis of 69 patients with hemophagocytic syndrome from a single-center in central region of China. Med Oncol, 31(4), 2014, 902.
    • (2014) Med Oncol , vol.31 , Issue.4 , pp. 902
    • Li, F.1    Li, P.2    Zhang, R.3    Yang, G.4    Ji, D.5    Huang, X.6
  • 77
    • 84885636323 scopus 로고    scopus 로고
    • Lymphoma-associated hemophagocytic lymphohistiocytosis: experience in adults from a single institution
    • [77] Yu, J.T., Wang, C.Y., Yang, Y., Wang, R.C., Chang, K.H., Hwang, W.L., et al. Lymphoma-associated hemophagocytic lymphohistiocytosis: experience in adults from a single institution. Ann Hematol 92:11 (2013), 1529–1536.
    • (2013) Ann Hematol , vol.92 , Issue.11 , pp. 1529-1536
    • Yu, J.T.1    Wang, C.Y.2    Yang, Y.3    Wang, R.C.4    Chang, K.H.5    Hwang, W.L.6
  • 78
    • 34249878987 scopus 로고    scopus 로고
    • Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome
    • [78] Han, A.R., Lee, H.R., Park, B.B., Hwang, I.G., Park, S., Lee, S.C., et al. Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome. Ann Hematol 86:7 (2007), 493–498.
    • (2007) Ann Hematol , vol.86 , Issue.7 , pp. 493-498
    • Han, A.R.1    Lee, H.R.2    Park, B.B.3    Hwang, I.G.4    Park, S.5    Lee, S.C.6
  • 79
    • 9844227365 scopus 로고    scopus 로고
    • Prognostic factors of hemophagocytic syndrome in adults: analysis of 34 cases
    • [79] Kaito, K., Kobayashi, M., Katayama, T., Otsubo, H., Ogasawara, Y., Sekita, T., et al. Prognostic factors of hemophagocytic syndrome in adults: analysis of 34 cases. Eur J Haematol 59:4 (1997), 247–253.
    • (1997) Eur J Haematol , vol.59 , Issue.4 , pp. 247-253
    • Kaito, K.1    Kobayashi, M.2    Katayama, T.3    Otsubo, H.4    Ogasawara, Y.5    Sekita, T.6
  • 80
    • 84937869949 scopus 로고    scopus 로고
    • Conditions associated with extreme hyperferritinaemia (> 3000 mug/L) in adults
    • [80] Wormsbecker, A.J., Sweet, D.D., Mann, S.L., Wang, S.Y., Pudek, M.R., Chen, L.Y., Conditions associated with extreme hyperferritinaemia (> 3000 mug/L) in adults. Intern Med J 45:8 (2015), 828–833.
    • (2015) Intern Med J , vol.45 , Issue.8 , pp. 828-833
    • Wormsbecker, A.J.1    Sweet, D.D.2    Mann, S.L.3    Wang, S.Y.4    Pudek, M.R.5    Chen, L.Y.6
  • 81
    • 37549037103 scopus 로고    scopus 로고
    • The role of hemophagocytosis in bone marrow aspirates in the diagnosis of hemophagocytic lymphohistiocytosis
    • [81] Gupta, A., Weitzman, S., Abdelhaleem, M., The role of hemophagocytosis in bone marrow aspirates in the diagnosis of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 50:2 (2008), 192–194.
    • (2008) Pediatr Blood Cancer , vol.50 , Issue.2 , pp. 192-194
    • Gupta, A.1    Weitzman, S.2    Abdelhaleem, M.3
  • 83
    • 84994769667 scopus 로고    scopus 로고
    • Long-term follow-up of HLH patients who received treatment with NI-0501, an anti-interferon gamma monoclonal antibody.
    • [83] NovImmune SA. Long-term follow-up of HLH patients who received treatment with NI-0501, an anti-interferon gamma monoclonal antibody. https://clinicaltrials.gov/ct2/show/NCT02069899.
    • NovImmune, S.A.1
  • 85
    • 84994717446 scopus 로고
    • Histiocytic medullary reticulocytosis
    • [85] Bodley Scott, R., Smith, A.H.T., Histiocytic medullary reticulocytosis. Lancet, 1939, 234519–234525.
    • (1939) Lancet , pp. 234519-234525
    • Bodley Scott, R.1    Smith, A.H.T.2
  • 86
    • 0000372673 scopus 로고
    • Familial haemophagocytic reticulosis
    • [86] Farquhar, J.W., Claireaux, A.E., Familial haemophagocytic reticulosis. Arch Dis Child 27:136 (1952), 519–525.
    • (1952) Arch Dis Child , vol.27 , Issue.136 , pp. 519-525
    • Farquhar, J.W.1    Claireaux, A.E.2
  • 87
    • 0035082616 scopus 로고    scopus 로고
    • Anaplastic large cell lymphoma: the shifting sands of diagnostic hematopathology
    • [87] Jaffe, E.S., Anaplastic large cell lymphoma: the shifting sands of diagnostic hematopathology. Mod Pathol 14:3 (2001), 219–228.
    • (2001) Mod Pathol , vol.14 , Issue.3 , pp. 219-228
    • Jaffe, E.S.1
  • 88
    • 0018656157 scopus 로고
    • Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis
    • [88] Risdall, R.J., McKenna, R.W., Nesbit, M.E., Krivit, W., Balfour, H.H. Jr., Simmons, R.L., et al. Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44:3 (1979), 993–1002.
    • (1979) Cancer , vol.44 , Issue.3 , pp. 993-1002
    • Risdall, R.J.1    McKenna, R.W.2    Nesbit, M.E.3    Krivit, W.4    Balfour, H.H.5    Simmons, R.L.6
  • 89
    • 0018936369 scopus 로고
    • Hemorrhagic diathesis associated with benign histiocytic, cytophagic panniculitis and systemic histiocytosis
    • [89] Winkelmann, R.K., Bowie, E.J., Hemorrhagic diathesis associated with benign histiocytic, cytophagic panniculitis and systemic histiocytosis. Arch Intern Med 140:11 (1980), 1460–1463.
    • (1980) Arch Intern Med , vol.140 , Issue.11 , pp. 1460-1463
    • Winkelmann, R.K.1    Bowie, E.J.2
  • 90
    • 0020578818 scopus 로고
    • Familial hemophagocytic lymphohistiocytosis
    • [90] Janka, G.E., Familial hemophagocytic lymphohistiocytosis. Eur J Pediatr 140:3 (1983), 221–230.
    • (1983) Eur J Pediatr , vol.140 , Issue.3 , pp. 221-230
    • Janka, G.E.1
  • 91
    • 0027364029 scopus 로고
    • Macrophage activation syndrome and rheumatic disease in childhood: a report of four new cases
    • [91] Stephan, J.L., Zeller, J., Hubert, P., Herbelin, C., Dayer, J.M., Prieur, A.M., Macrophage activation syndrome and rheumatic disease in childhood: a report of four new cases. Clin Exp Rheumatol 11:4 (1993), 451–456.
    • (1993) Clin Exp Rheumatol , vol.11 , Issue.4 , pp. 451-456
    • Stephan, J.L.1    Zeller, J.2    Hubert, P.3    Herbelin, C.4    Dayer, J.M.5    Prieur, A.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.