-
3
-
-
0033520970
-
Perforin gene defects in familial hemophagocytic lymphohistiocytosis
-
Stepp SE, Dufourcq-Lagelouse R, Le Deist F, Bhawan S, Certain S, et al. (1999) Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 286: 1957-1959.
-
(1999)
Science
, vol.286
, pp. 1957-1959
-
-
Stepp, S.E.1
Dufourcq-Lagelouse, R.2
Le Deist, F.3
Bhawan, S.4
Certain, S.5
-
4
-
-
2942627114
-
Atypical features of familial hemophagocytic lymphohistiocytosis
-
Busiello R, Adriani M, Locatelli F, Galgani M, Fimiani G, et al. (2004) Atypical features of familial hemophagocytic lymphohistiocytosis. Blood 103: 4610-4612.
-
(2004)
Blood
, vol.103
, pp. 4610-4612
-
-
Busiello, R.1
Adriani, M.2
Locatelli, F.3
Galgani, M.4
Fimiani, G.5
-
5
-
-
36749027637
-
Novel spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis in ethnic Omani patients
-
Muralitharan S, Wali YA, Dennison D, Lamki ZA, Zachariah M, et al. (2007) Novel spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis in ethnic Omani patients. Am J Hematol 82: 1099-1102.
-
(2007)
Am J Hematol
, vol.82
, pp. 1099-1102
-
-
Muralitharan, S.1
Wali, Y.A.2
Dennison, D.3
Lamki, Z.A.4
Zachariah, M.5
-
6
-
-
72849125357
-
-
and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest
-
Cote M, Menager MM, Burgess A, Mahlaoui N, Picard C, et al. (2009) Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest.
-
(2009)
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type
, vol.5
-
-
Cote, M.1
Menager, M.M.2
Burgess, A.3
Mahlaoui, N.4
Picard, C.5
-
7
-
-
0025787766
-
Hypercytokinemia in familial hemophagocytic lymphohistiocytosis
-
Henter JI, Elinder G, Soder O, Hansson M, Andersson B, et al. (1991) Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood 78: 2918-2922.
-
(1991)
Blood
, vol.78
, pp. 2918-2922
-
-
Henter, J.I.1
Elinder, G.2
Soder, O.3
Hansson, M.4
Andersson, B.5
-
8
-
-
0025857198
-
Prognosis of children with virus-associated hemophagocytic syndrome and malignant histiocytosis: Correlation with levels of serum interleukin-1 and tumor necrosis factor
-
Ishii E, Ohga S, Aoki T, Yamada S, Sako M, et al. (1991) Prognosis of children with virus-associated hemophagocytic syndrome and malignant histiocytosis: correlation with levels of serum interleukin-1 and tumor necrosis factor. Acta Haematol 85: 93-99.
-
(1991)
Acta Haematol
, vol.85
, pp. 93-99
-
-
Ishii, E.1
Ohga, S.2
Aoki, T.3
Yamada, S.4
Sako, M.5
-
9
-
-
17744414197
-
Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis
-
Osugi Y, Hara J, Tagawa S, Takai K, Hosoi G, et al. (1997) Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood 89: 4100-4103.
-
(1997)
Blood
, vol.89
, pp. 4100-4103
-
-
Osugi, Y.1
Hara, J.2
Tagawa, S.3
Takai, K.4
Hosoi, G.5
-
10
-
-
33847336449
-
Interleukin-18 and the pathogenesis of inflammatory diseases
-
Dinarello CA (2007) Interleukin-18 and the pathogenesis of inflammatory diseases. Semin Nephrol 27: 98-114.
-
(2007)
Semin Nephrol
, vol.27
, pp. 98-114
-
-
Dinarello, C.A.1
-
11
-
-
27744607629
-
Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome
-
Mazodier K, Marin V, Novick D, Farnarier C, Robitail S, et al. (2005) Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome. Blood 106: 3483-3489.
-
(2005)
Blood
, vol.106
, pp. 3483-3489
-
-
Mazodier, K.1
Marin, V.2
Novick, D.3
Farnarier, C.4
Robitail, S.5
-
12
-
-
0034926839
-
Interleukin-18 in hemophagocytic lymphohistiocytosis
-
Takada H, Nomura A, Ohga S, Hara T (2001) Interleukin-18 in hemophagocytic lymphohistiocytosis. Leuk Lymphoma 42: 21-28.
-
(2001)
Leuk Lymphoma
, vol.42
, pp. 21-28
-
-
Takada, H.1
Nomura, A.2
Ohga, S.3
Hara, T.4
-
13
-
-
0032855445
-
Oversecretion of IL-18 in haemophagocytic lymphohistiocytosis: A novel marker of disease activity
-
Takada H, Ohga S, Mizuno Y, Suminoe A, Matsuzaki A, et al. (1999) Oversecretion of IL-18 in haemophagocytic lymphohistiocytosis: a novel marker of disease activity. Br J Haematol 106: 182-189.
-
(1999)
Br J Haematol
, vol.106
, pp. 182-189
-
-
Takada, H.1
Ohga, S.2
Mizuno, Y.3
Suminoe, A.4
Matsuzaki, A.5
-
14
-
-
3242752040
-
An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
-
Jordan MB, Hildeman D, Kappler J, Marrack P (2004) An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 104: 735-743.
-
(2004)
Blood
, vol.104
, pp. 735-743
-
-
Jordan, M.B.1
Hildeman, D.2
Kappler, J.3
Marrack, P.4
-
15
-
-
0032983336
-
Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response
-
Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, et al. (1999) Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 10: 127-136.
-
(1999)
Immunity
, vol.10
, pp. 127-136
-
-
Novick, D.1
Kim, S.H.2
Fantuzzi, G.3
Reznikov, L.L.4
Dinarello, C.A.5
-
16
-
-
0030937079
-
HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society
-
Henter JI, Arico M, Egeler RM, Elinder G, Favara BE, et al. (1997) HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society. Med Pediatr Oncol 28: 342-347.
-
(1997)
Med Pediatr Oncol
, vol.28
, pp. 342-347
-
-
Henter, J.I.1
Arico, M.2
Egeler, R.M.3
Elinder, G.4
Favara, B.E.5
-
17
-
-
0036786375
-
Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
-
Henter JI, Samuelsson-Horne A, Arico M, Egeler RM, Elinder G, et al. (2002) Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood 100: 2367-2373.
-
(2002)
Blood
, vol.100
, pp. 2367-2373
-
-
Henter, J.I.1
Samuelsson-Horne, A.2
Arico, M.3
Egeler, R.M.4
Elinder, G.5
-
18
-
-
27144455830
-
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia
-
Lehrnbecher T, Bernig T, Hanisch M, Koehl U, Behl M, et al. (2005) Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia. Leukemia 19: 1745-1750.
-
(2005)
Leukemia
, vol.19
, pp. 1745-1750
-
-
Lehrnbecher, T.1
Bernig, T.2
Hanisch, M.3
Koehl, U.4
Behl, M.5
-
19
-
-
0037672908
-
Detection of common cytokine and colony stimulating factor gene polymorphisms
-
Lehrnbecher T, Chanock SJ (2003) Detection of common cytokine and colony stimulating factor gene polymorphisms. Methods Mol Biol 215: 71-93.
-
(2003)
Methods Mol Biol
, vol.215
, pp. 71-93
-
-
Lehrnbecher, T.1
Chanock, S.J.2
-
20
-
-
0032189103
-
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
-
Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, et al. (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 102: 1369-1376.
-
(1998)
J Clin Invest
, vol.102
, pp. 1369-1376
-
-
Fishman, D.1
Faulds, G.2
Jeffery, R.3
Mohamed-Ali, V.4
Yudkin, J.S.5
-
21
-
-
0035892991
-
Expression and release of IL-18 binding protein in response to IFN-gamma
-
Paulukat J, Bosmann M, Nold M, Garkisch S, Kampfer H, et al. (2001) Expression and release of IL-18 binding protein in response to IFN-gamma. J Immunol 167: 7038-7043.
-
(2001)
J Immunol
, vol.167
, pp. 7038-7043
-
-
Paulukat, J.1
Bosmann, M.2
Nold, M.3
Garkisch, S.4
Kampfer, H.5
-
22
-
-
0036379347
-
Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients
-
Kaser A, Novick D, Rubinstein M, Siegmund B, Enrich B, et al. (2002) Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients. Clin Exp Immunol 129: 332-338.
-
(2002)
Clin Exp Immunol
, vol.129
, pp. 332-338
-
-
Kaser, A.1
Novick, D.2
Rubinstein, M.3
Siegmund, B.4
Enrich, B.5
-
23
-
-
0037168677
-
The promoter of IL-18 binding protein: Activation by an IFN-gamma -induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta
-
Hurgin V, Novick D, Rubinstein M (2002) The promoter of IL-18 binding protein: activation by an IFN-gamma -induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta. Proc Natl Acad Sci U S A 99: 16957-16962.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16957-16962
-
-
Hurgin, V.1
Novick, D.2
Rubinstein, M.3
-
25
-
-
75349084506
-
-
Novick D, Elbirt D, Miller G, Dinarello CA, Rubinstein M, et al. (2009) High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. J Autoimmun.
-
Novick D, Elbirt D, Miller G, Dinarello CA, Rubinstein M, et al. (2009) High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein. J Autoimmun.
-
-
-
-
26
-
-
59449088786
-
Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis
-
Novick D, Elbirt D, Dinarello CA, Rubinstein M, Sthoeger ZM (2009) Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis. J Clin Immunol 29: 38-45.
-
(2009)
J Clin Immunol
, vol.29
, pp. 38-45
-
-
Novick, D.1
Elbirt, D.2
Dinarello, C.A.3
Rubinstein, M.4
Sthoeger, Z.M.5
-
27
-
-
0036095443
-
Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members
-
Kogawa K, Lee SM, Villanueva J, Marmer D, Sumegi J, et al. (2002) Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members. Blood 99: 61-66.
-
(2002)
Blood
, vol.99
, pp. 61-66
-
-
Kogawa, K.1
Lee, S.M.2
Villanueva, J.3
Marmer, D.4
Sumegi, J.5
-
28
-
-
0031670358
-
Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives
-
Sullivan KE, Delaat CA, Douglas SD, Filipovich AH (1998) Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives. Pediatr Res 44: 465-468.
-
(1998)
Pediatr Res
, vol.44
, pp. 465-468
-
-
Sullivan, K.E.1
Delaat, C.A.2
Douglas, S.D.3
Filipovich, A.H.4
-
29
-
-
15944399347
-
Perforin and lymphohistiocytic proliferative disorders
-
Katano H, Cohen JI (2005) Perforin and lymphohistiocytic proliferative disorders. Br J Haematol 128: 739-750.
-
(2005)
Br J Haematol
, vol.128
, pp. 739-750
-
-
Katano, H.1
Cohen, J.I.2
-
30
-
-
33645767911
-
Insufficient perforin expression in CD8+ T cells in response to hemagglutinin from avian influenza (H5N1) virus
-
Hsieh SM, Chang SC (2006) Insufficient perforin expression in CD8+ T cells in response to hemagglutinin from avian influenza (H5N1) virus. J Immunol 176: 4530-4533.
-
(2006)
J Immunol
, vol.176
, pp. 4530-4533
-
-
Hsieh, S.M.1
Chang, S.C.2
-
31
-
-
0037038866
-
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
-
Cheung CY, Poon LL, Lau AS, Luk W, Lau YL, et al. (2002) Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 360: 1831-1837.
-
(2002)
Lancet
, vol.360
, pp. 1831-1837
-
-
Cheung, C.Y.1
Poon, L.L.2
Lau, A.S.3
Luk, W.4
Lau, Y.L.5
-
32
-
-
20144387310
-
Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: The role of cytokines and B- and T-cell responses
-
Lipatov AS, Andreansky S, Webby RJ, Hulse DJ, Rehg JE, et al. (2005) Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses. J Gen Virol 86: 1121-1130.
-
(2005)
J Gen Virol
, vol.86
, pp. 1121-1130
-
-
Lipatov, A.S.1
Andreansky, S.2
Webby, R.J.3
Hulse, D.J.4
Rehg, J.E.5
-
33
-
-
0034009765
-
Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins
-
Smith VP, Bryant NA, Alcami A (2000) Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins. J Gen Virol 81: 1223-1230.
-
(2000)
J Gen Virol
, vol.81
, pp. 1223-1230
-
-
Smith, V.P.1
Bryant, N.A.2
Alcami, A.3
-
34
-
-
52249093922
-
Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis
-
Tamura K, Kanazawa T, Tsukada S, Kobayashi T, Kawamura M, et al. (2008) Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 51: 662-668.
-
(2008)
Pediatr Blood Cancer
, vol.51
, pp. 662-668
-
-
Tamura, K.1
Kanazawa, T.2
Tsukada, S.3
Kobayashi, T.4
Kawamura, M.5
-
35
-
-
0036251485
-
Reactive hemophagocytic syndrome associated with thrombotic thrombocytopenic purpura during therapeutic plasma exchange
-
Kfoury Baz EM, Mikati AR, Kanj NA (2002) Reactive hemophagocytic syndrome associated with thrombotic thrombocytopenic purpura during therapeutic plasma exchange. Ther Apher 6: 159-162.
-
(2002)
Ther Apher
, vol.6
, pp. 159-162
-
-
Kfoury Baz, E.M.1
Mikati, A.R.2
Kanj, N.A.3
-
36
-
-
0031306711
-
Host defensive, immunological, and microbiological observations of an early-onset periodontitis patient with virus-associated hemophagocytic syndrome
-
Kono T, Takigawa M, Nishimura F, Takashiba S, Nakagawa M, et al. (1997) Host defensive, immunological, and microbiological observations of an early-onset periodontitis patient with virus-associated hemophagocytic syndrome. J Periodontol 68: 1223-1230.
-
(1997)
J Periodontol
, vol.68
, pp. 1223-1230
-
-
Kono, T.1
Takigawa, M.2
Nishimura, F.3
Takashiba, S.4
Nakagawa, M.5
-
37
-
-
0038326688
-
Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, et al. (2003) Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol 170: 4886-4890.
-
(2003)
J Immunol
, vol.170
, pp. 4886-4890
-
-
Takeda, A.1
Hamano, S.2
Yamanaka, A.3
Hanada, T.4
Ishibashi, T.5
-
38
-
-
34447345406
-
The biology and therapeutic potential of interleukin 27
-
Batten M, Ghilardi N (2007) The biology and therapeutic potential of interleukin 27. J Mol Med 85: 661-672.
-
(2007)
J Mol Med
, vol.85
, pp. 661-672
-
-
Batten, M.1
Ghilardi, N.2
|