A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice

Blood

Volumn 125, Issue 9, 2015, Pages 1427-1434

  Sepulveda, Fernando E ^a,b   Maschalidi, Sophia ^a,b   Vosshenrich, Christian A J ^c,d   Garrigue, Alexandrine ^a,b   Kurowska, Mathieu ^a,b   Ménasche, Gael ^a,b   Fischer, Alain ^a,b,e,f   Di Santo, James P ^c,d   De Saint Basile, Geneviève ^a,b,e  

^a INSERM   (France)

^b IMAGINE INSTITUTE   (France)

^c INSTITUT PASTEUR   (France)

^d INSTITUT PASTEUR   (France)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

^f Centre de Recherche Interdisciplinaire en Biologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISEASE SEVERITY; HEMOPHAGOCYTIC SYNDROME; IMMUNOPATHOLOGY; IMMUNOREGULATION; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; VIRUS LOAD; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CYTOTOXICITY; IMMUNOLOGY; PATHOLOGY; SECRETION (PROCESS); SPLEEN; VIROLOGY;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; INTERFERON-GAMMA; KILLER CELLS, NATURAL; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MICE; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTES, CYTOTOXIC; VIRAL LOAD;

EID: 84927610290     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-09-602946     Document Type: Article

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