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Volumn 139, Issue 6, 2013, Pages 713-727

Hemophagocytic lymphohistiocytosis

Author keywords

Acquired; Genetic; Hemophagocytic lymphohistiocytosis; Hypercytokinemia; Macrophage activation syndrome; Perforin

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN A; ETOPOSIDE; GAMMA INTERFERON; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; FERRITIN; PERFORIN;

EID: 84878384497     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCP4ZDKJ4ICOUAT     Document Type: Review
Times cited : (259)

References (139)
  • 1
  • 2
    • 84855932987 scopus 로고    scopus 로고
    • Familial and acquired hemophagocytic lymphohistiocytosis
    • Janka GE. Familial and acquired hemophagocytic lymphohistiocytosis. Annu Rev Med. 2012; 63: 233-246.
    • (2012) Annu Rev Med , vol.63 , pp. 233-246
    • Janka, G.E.1
  • 3
    • 0026065540 scopus 로고
    • Diagnostic guidelines for hemophagocytic lymphohistiocytosis
    • The FHL Study Group of the Histiocyte Society
    • Henter JI, Elinder G, Ost A. Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Semin Oncol. 1991; 18: 29-33.
    • (1991) Semin Oncol , vol.18 , pp. 29-33
    • Henter, J.I.1    Elinder, G.2    Ost, A.3
  • 4
    • 0036460574 scopus 로고    scopus 로고
    • Spontaneous resolution of hemophagocytic syndrome associated with acute parvovirus B19 infection and concomitant epstein-barr virus reactivation in an otherwise healthy adult
    • DOI 10.1007/s10096-002-0793-2
    • Larroche C, Scieux C, Honderlick P, et al. Spontaneous resolution of hemophagocytic syndrome associated with acute parvovirus B19 infection and concomitant Epstein-Barr virus reactivation in an otherwise healthy adult. Eur J Clin Microbiol Infect Dis. 2002; 21:739-742. (Pubitemid 35477928)
    • (2002) European Journal of Clinical Microbiology and Infectious Diseases , vol.21 , Issue.10 , pp. 739-742
    • Larroche, C.1    Scieux, C.2    Honderlick, P.3    Piette, A.M.4    Morinet, F.5    Bletry, O.6
  • 6
    • 0037105371 scopus 로고    scopus 로고
    • Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations [1]
    • DOI 10.1182/blood-2002-04-1030
    • Clementi R, Emmi L, Maccario R, et al. Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations. Blood. 2002;100:2266-2267. (Pubitemid 35001269)
    • (2002) Blood , vol.100 , Issue.6 , pp. 2266-2267
    • Clementi, R.1    Emmi, L.2    Maccario, R.3    Liotta, F.4    Moretta, L.5    Danesino, C.6    Arico, M.7
  • 7
    • 31744445155 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: Diagnosis, pathophysiology, treatment, and future perspectives
    • DOI 10.1080/07853890500465189, PII M38007104L972271
    • Verbsky JW, Grossman WJ. Hemophagocytic lymphohistiocytosis: diagnosis, pathophysiology, treatment, and future perspectives. Ann Med. 2006;38:20-31. (Pubitemid 43177784)
    • (2006) Annals of Medicine , vol.38 , Issue.1 , pp. 20-31
    • Verbsky, J.W.1    Grossman, W.J.2
  • 9
    • 0020578818 scopus 로고
    • Familial hemophagocytic lymphohistiocytosis
    • Janka GE. Familial hemophagocytic lymphohistiocytosis. Eur J Pediatr. 1983;140:221-230. (Pubitemid 13026976)
    • (1983) European Journal of Pediatrics , vol.140 , Issue.3 , pp. 221-230
    • Janka, G.E.1
  • 10
    • 79551703613 scopus 로고    scopus 로고
    • Familial haemophagocytic lymphohistiocytosis: Advances in the genetic basis, diagnosis and management
    • Gholam C, Grigoriadou S, Gilmour KC, et al. Familial haemophagocytic lymphohistiocytosis: advances in the genetic basis, diagnosis and management. Clin Exp Immunol. 2011; 163: 271-283.
    • (2011) Clin Exp Immunol , vol.163 , pp. 271-283
    • Gholam, C.1    Grigoriadou, S.2    Gilmour, K.C.3
  • 11
    • 79953007434 scopus 로고    scopus 로고
    • Review of haemophagocytic lymphohistiocytosis
    • Freeman HR, Ramanan AV. Review of haemophagocytic lymphohistiocytosis. Arch Dis Child. 2011; 96: 688-693.
    • (2011) Arch Dis Child , vol.96 , pp. 688-693
    • Freeman, H.R.1    Ramanan, A.V.2
  • 12
    • 76749084228 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in Texas: Observations on ethnicity and race
    • Niece JA, Rogers ZR, Ahmad N, et al. Hemophagocytic lymphohistiocytosis in Texas: observations on ethnicity and race. Pediatr Blood Cancer. 2010; 54: 424-428.
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 424-428
    • Niece, J.A.1    Rogers, Z.R.2    Ahmad, N.3
  • 13
    • 0026061971 scopus 로고
    • Incidence in Sweden and clinical features of familial hemophagocytic lymphohistiocytosis
    • Henter JI, Elinder G, Soder O, et al. Incidence in Sweden and clinical features of familial hemophagocytic lymphohistiocytosis. Acta Paediatr Scand. 1991; 80: 428-435.
    • (1991) Acta Paediatr Scand , vol.80 , pp. 428-435
    • Henter, J.I.1    Elinder, G.2    Soder, O.3
  • 17
    • 0026321653 scopus 로고
    • Fulminant childhood hemophagocytic syndrome mimicking histiocytic medullary reticulosis: An atypical form of Epstein-Barr virus infection
    • Chen RL, Su IJ, Lin KH, et al. Fulminant childhood hemophagocytic syndrome mimicking histiocytic medullary reticulosis: an atypical form of Epstein-Barr virus infection. Am J Clin Pathol. 1991; 96: 171-176.
    • (1991) Am J Clin Pathol , vol.96 , pp. 171-176
    • Chen, R.L.1    Su, I.J.2    Lin, K.H.3
  • 18
    • 70350555315 scopus 로고    scopus 로고
    • Macrophage activation syndrome in juvenile systemic lupus erythematosus: A multinational multicenter study of thirty-eight patients
    • Parodi A, Davi S, Pringe AB, et al. Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients. Arthritis Rheum. 2009; 60: 3388-3399.
    • (2009) Arthritis Rheum , vol.60 , pp. 3388-3399
    • Parodi, A.1    Davi, S.2    Pringe, A.B.3
  • 19
    • 77950939305 scopus 로고    scopus 로고
    • Macrophage activation syndrome in autoimmune disease
    • Deane S, Selmi C, Teuber SS, et al. Macrophage activation syndrome in autoimmune disease. Int Arch Allergy Immunol. 2010; 153: 109-120.
    • (2010) Int Arch Allergy Immunol , vol.153 , pp. 109-120
    • Deane, S.1    Selmi, C.2    Teuber, S.S.3
  • 20
    • 0036092488 scopus 로고    scopus 로고
    • Severe hemophagocytic syndrome after intravesical BCG instillation [5]
    • DOI 10.1016/S0002-9343(02)01066-5, PII S0002934302010665
    • Schleinitz N, Bernit E, Harle JR. Severe hemophagocytic syndrome after intravesical BCG instillation. Am J Med. 2002;112:593-594. (Pubitemid 34518327)
    • (2002) American Journal of Medicine , vol.112 , Issue.7 , pp. 593-594
    • Schleinitz, N.1    Bernit, E.2    Harle, J.-R.3
  • 21
    • 77957579854 scopus 로고    scopus 로고
    • Critical care management of patients with hemophagocytic lymphohistiocytosis
    • Buyse S, Teixeira L, Galicier L, et al. Critical care management of patients with hemophagocytic lymphohistiocytosis. Intensive Care Med. 2010; 36: 1695-1702.
    • (2010) Intensive Care Med , vol.36 , pp. 1695-1702
    • Buyse, S.1    Teixeira, L.2    Galicier, L.3
  • 23
    • 68849131525 scopus 로고    scopus 로고
    • Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation
    • Castillo L, Carcillo J. Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation. Pediatr Crit Care Med. 2009; 10: 387-392.
    • (2009) Pediatr Crit Care Med , vol.10 , pp. 387-392
    • Castillo, L.1    Carcillo, J.2
  • 26
    • 84866850944 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis with isolated central nervous system reactivation and optic nerve involvement
    • Chong KW, Lee JH, Choong CT, et al. Hemophagocytic lymphohistiocytosis with isolated central nervous system reactivation and optic nerve involvement. J Child Neurol. 2012; 27: 1336-1339.
    • (2012) J Child Neurol , vol.27 , pp. 1336-1339
    • Chong, K.W.1    Lee, J.H.2    Choong, C.T.3
  • 27
    • 54549086882 scopus 로고    scopus 로고
    • Central nervous system involvement in Turkish children with primary hemophagocytic lymphohistiocytosis
    • Gurgey A, Aytac S, Balta G, et al. Central nervous system involvement in Turkish children with primary hemophagocytic lymphohistiocytosis. J Child Neurol. 2008; 23: 1293-1299.
    • (2008) J Child Neurol , vol.23 , pp. 1293-1299
    • Gurgey, A.1    Aytac, S.2    Balta, G.3
  • 28
    • 0026569537 scopus 로고
    • Cerebromeningeal haemophagocytic lymphohistiocytosis
    • Henter JI, Elinder G. Cerebromeningeal haemophagocytic lymphohistiocytosis. Lancet. 1992; 339: 104-107.
    • (1992) Lancet , vol.339 , pp. 104-107
    • Henter, J.I.1    Elinder, G.2
  • 29
    • 0037736671 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis masquerading as child abuse: Presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis
    • Rooms L, Fitzgerald N, McClain KL. Hemophagocytic lymphohistiocytosis masquerading as child abuse: presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis. Pediatrics. 2003; 111( pt 1): e636-e640.
    • (2003) Pediatrics , vol.111 , Issue.PART 1
    • Rooms, L.1    Fitzgerald, N.2    McClain, K.L.3
  • 30
    • 67651085515 scopus 로고    scopus 로고
    • Characteristics of hemophagocytic lymphohistiocytosis in neonates: A nationwide survey in Japan
    • Suzuki N, Morimoto A, Ohga S, et al. Characteristics of hemophagocytic lymphohistiocytosis in neonates: a nationwide survey in Japan. J Pediatr. 2009; 155: 235-238.e1.
    • (2009) J Pediatr , vol.155
    • Suzuki, N.1    Morimoto, A.2    Ohga, S.3
  • 31
    • 77949704386 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: When the immune system runs amok
    • Janka G. Hemophagocytic lymphohistiocytosis: when the immune system runs amok. Klin Padiatr. 2009; 221: 278-285.
    • (2009) Klin Padiatr , vol.221 , pp. 278-285
    • Janka, G.1
  • 32
    • 42349095543 scopus 로고    scopus 로고
    • Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis
    • DOI 10.1002/pbc.21423
    • Allen CE, Yu X, Kozinetz CA, et al. Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2008;50:1227-1235. (Pubitemid 351555548)
    • (2008) Pediatric Blood and Cancer , vol.50 , Issue.6 , pp. 1227-1235
    • Allen, C.E.1    Yu, X.2    Kozinetz, C.A.3    McClain, K.L.4
  • 33
    • 0037108557 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosis
    • Schneider EM, Lorenz I, Muller-Rosenberger M, et al. Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosis. Blood. 2002; 100: 2891-2898.
    • (2002) Blood , vol.100 , pp. 2891-2898
    • Schneider, E.M.1    Lorenz, I.2    Muller-Rosenberger, M.3
  • 35
    • 84868561761 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis associated with influenza A (H1N1) infection in a patient with chronic lymphocytic leukemia: An autopsy case report and review of the literature
    • Lai S, Merritt BY, Chen L, et al. Hemophagocytic lymphohistiocytosis associated with influenza A (H1N1) infection in a patient with chronic lymphocytic leukemia: an autopsy case report and review of the literature. Ann Diagn Pathol. 2012; 16: 477-484.
    • (2012) Ann Diagn Pathol , vol.16 , pp. 477-484
    • Lai, S.1    Merritt, B.Y.2    Chen, L.3
  • 38
    • 77955028074 scopus 로고    scopus 로고
    • Cytophagic histiocytic panniculitis and hemophagocytic lymphohistiocytosis: An overview
    • Aronson IK, Worobec SM. Cytophagic histiocytic panniculitis and hemophagocytic lymphohistiocytosis: an overview. Dermatol Ther. 2010; 23: 389-402.
    • (2010) Dermatol Ther , vol.23 , pp. 389-402
    • Aronson, I.K.1    Worobec, S.M.2
  • 40
    • 77953036658 scopus 로고    scopus 로고
    • Pathology of the liver in familial hemophagocytic lymphohistiocytosis
    • Chen JH, Fleming MD, Pinkus GS, et al. Pathology of the liver in familial hemophagocytic lymphohistiocytosis. Am J Surg Pathol. 2010; 34: 852-867.
    • (2010) Am J Surg Pathol , vol.34 , pp. 852-867
    • Chen, J.H.1    Fleming, M.D.2    Pinkus, G.S.3
  • 41
    • 33646776086 scopus 로고    scopus 로고
    • Peripheral hemophagocytosis: An early indicator of advanced systemic inflammatory response syndrome/hemophagocytic syndrome
    • Kuwata K, Yamada S, Kinuwaki E, et al. Peripheral hemophagocytosis: an early indicator of advanced systemic inflammatory response syndrome/ hemophagocytic syndrome. Shock. 2006; 25: 344-350.
    • (2006) Shock , vol.25 , pp. 344-350
    • Kuwata, K.1    Yamada, S.2    Kinuwaki, E.3
  • 42
    • 2942597667 scopus 로고    scopus 로고
    • Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients - A postmortem clinicopathologic analysis
    • DOI 10.1097/01.CCM.0000127779.24232.15
    • Strauss R, Neureiter D, Westenburger B, et al. Multifactorial risk analysis of bone marrow histiocytic hyperplasia with hemophagocytosis in critically ill medical patients - a postmortem clinicopathologic analysis. Crit Care Med. 2004;32:1316-1321. (Pubitemid 38738586)
    • (2004) Critical Care Medicine , vol.32 , Issue.6 , pp. 1316-1321
    • Strauss, R.1    Neureiter, D.2    Westenburger, B.3    Wehler, M.4    Kirchner, T.5    Hahn, E.G.6
  • 45
    • 77649169379 scopus 로고    scopus 로고
    • Primary and secondary hemophagocytic lymphohistiocytosis: Clinical features, pathogenesis and therapy
    • Gupta S, Weitzman S. Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy. Expert Rev Clin Immunol. 2010; 6: 137-154.
    • (2010) Expert Rev Clin Immunol , vol.6 , pp. 137-154
    • Gupta, S.1    Weitzman, S.2
  • 46
    • 0347064083 scopus 로고    scopus 로고
    • Modern management of children with haemophagocytic lymphohistiocytosis
    • DOI 10.1046/j.1365-2141.2003.04726.x
    • Janka GE, Schneider EM. Modern management of children with haemophagocytic lymphohistiocytosis. Br J Haematol. 2004;124:4-14. (Pubitemid 38021618)
    • (2004) British Journal of Haematology , vol.124 , Issue.1 , pp. 4-14
    • Janka, G.E.1    Schneider, E.M.2
  • 47
    • 84861685616 scopus 로고    scopus 로고
    • Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: Diagnosis, genetics, pathophysiology and treatment
    • Ravelli A, Grom AA, Behrens EM, et al. Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment. Genes Immun. 2012; 13: 289-298.
    • (2012) Genes Immun , vol.13 , pp. 289-298
    • Ravelli, A.1    Grom, A.A.2    Behrens, E.M.3
  • 50
    • 13144259647 scopus 로고    scopus 로고
    • Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis
    • DOI 10.1111/j.0105-2896.2005.00224.x
    • Menasche G, Feldmann J, Fischer A, et al. Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis. Immunol Rev. 2005;203:165-179. (Pubitemid 40179701)
    • (2005) Immunological Reviews , vol.203 , pp. 165-179
    • Menasche, G.1    Feldmann, J.2    Fischer, A.3    De Saint, B.G.4
  • 54
    • 70350500464 scopus 로고    scopus 로고
    • Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
    • zur Stadt U, Rohr J, Seifert W, et al. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. Am J Hum Genet. 2009; 85: 482-492.
    • (2009) Am J Hum Genet , vol.85 , pp. 482-492
    • Zur Stadt, U.1    Rohr, J.2    Seifert, W.3
  • 56
    • 77950656593 scopus 로고    scopus 로고
    • Molecular basis of familial hemophagocytic lymphohistiocytosis
    • Cetica V, Pende D, Griffiths GM, et al. Molecular basis of familial hemophagocytic lymphohistiocytosis. Haematologica. 2010; 95: 538-541.
    • (2010) Haematologica , vol.95 , pp. 538-541
    • Cetica, V.1    Pende, D.2    Griffiths, G.M.3
  • 57
    • 78650811211 scopus 로고    scopus 로고
    • Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders
    • Johnson TS, Villanueva J, Filipovich AH, et al. Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders. J Immunol Methods. 2011; 364: 1-13.
    • (2011) J Immunol Methods , vol.364 , pp. 1-13
    • Johnson, T.S.1    Villanueva, J.2    Filipovich, A.H.3
  • 58
    • 68849113307 scopus 로고    scopus 로고
    • Severe course of community-acquired pneumonia in an adult patient who is heterozygous for Q481P in the perforin gene: Are carriers of the mutation free of risk?
    • Garcia-Astudillo LA, Fontalba A, Mazorra F, et al. Severe course of community-acquired pneumonia in an adult patient who is heterozygous for Q481P in the perforin gene: are carriers of the mutation free of risk? J Investig Allergol Clin Immunol. 2009; 19: 311-316.
    • (2009) J Investig Allergol Clin Immunol , vol.19 , pp. 311-316
    • Garcia-Astudillo, L.A.1    Fontalba, A.2    Mazorra, F.3
  • 60
    • 0036095443 scopus 로고    scopus 로고
    • Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members
    • Kogawa K, Lee SM, Villanueva J, et al. Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members. Blood. 2002; 99: 61-66.
    • (2002) Blood , vol.99 , pp. 61-66
    • Kogawa, K.1    Lee, S.M.2    Villanueva, J.3
  • 61
    • 33749349937 scopus 로고    scopus 로고
    • Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): Defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease
    • DOI 10.1182/blood-2006-04-015693
    • Marcenaro S, Gallo F, Martini S, et al. Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease. Blood. 2006;108:2316-2323. (Pubitemid 44497515)
    • (2006) Blood , vol.108 , Issue.7 , pp. 2316-2323
    • Marcenaro, S.1    Gallo, F.2    Martini, S.3    Santoro, A.4    Griffiths, G.M.5    Arico, M.6    Moretta, L.7    Pende, D.8
  • 62
    • 17044424680 scopus 로고    scopus 로고
    • Rapid detection of intracellular SH2D1A protein in cytotoxic lymphocytes from patients with X-linked lymphoproliferative disease and their family members
    • Tabata Y, Villanueva J, Lee SM, et al. Rapid detection of intracellular SH2D1A protein in cytotoxic lymphocytes from patients with X-linked lymphoproliferative disease and their family members. Blood. 2005; 105: 3066-3071.
    • (2005) Blood , vol.105 , pp. 3066-3071
    • Tabata, Y.1    Villanueva, J.2    Lee, S.M.3
  • 63
    • 0033037049 scopus 로고    scopus 로고
    • Hemophagocytic syndrome presenting as acute hepatic failure in two infants: Clinical overlap with neonatal hemochromatosis
    • DOI 10.1007/s100249900135
    • Parizhskaya M, Reyes J, Jaffe R. Hemophagocytic syndrome presenting as acute hepatic failure in two infants: clinical overlap with neonatal hemochromatosis. Pediatr Dev Pathol. 1999;2:360-366. (Pubitemid 29290852)
    • (1999) Pediatric and Developmental Pathology , vol.2 , Issue.4 , pp. 360-366
    • Parizhskaya, M.1    Reyes, J.2    Jaffe, R.3
  • 64
    • 67651219441 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis and Kawasaki disease: Combined manifestation and differential diagnosis
    • Titze U, Janka G, Schneider EM, et al. Hemophagocytic lymphohistiocytosis and Kawasaki disease: combined manifestation and differential diagnosis. Pediatr Blood Cancer. 2009; 53: 493-495.
    • (2009) Pediatr Blood Cancer , vol.53 , pp. 493-495
    • Titze, U.1    Janka, G.2    Schneider, E.M.3
  • 66
    • 1542283765 scopus 로고    scopus 로고
    • Natural Killer Cell Dysfunction: A Common Pathway in Systemic-Onset Juvenile Rheumatoid Arthritis, Macrophage Activation Syndrome, and Hemophagocytic Lymphohistiocytosis?
    • DOI 10.1002/art.20198
    • Grom AA. Natural killer cell dysfunction: a common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis? Arthritis Rheum. 2004;50:689-698. (Pubitemid 38326166)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.3 , pp. 689-698
    • Grom, A.A.1
  • 67
    • 0023813169 scopus 로고
    • Structure and function of human perforin
    • Lichtenheld MG, Olsen KJ, Lu P, et al. Structure and function of human perforin. Nature. 1988; 335: 448-451.
    • (1988) Nature , vol.335 , pp. 448-451
    • Lichtenheld, M.G.1    Olsen, K.J.2    Lu, P.3
  • 68
    • 34547842304 scopus 로고    scopus 로고
    • Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: Nuclear factor-kappa B pathway as a potential therapeutic target
    • Chuang HC, Lay JD, Hsieh WC, et al. Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: nuclear factor-kappa B pathway as a potential therapeutic target. Cancer Sci. 2007; 98: 1281-1287.
    • (2007) Cancer Sci , vol.98 , pp. 1281-1287
    • Chuang, H.C.1    Lay, J.D.2    Hsieh, W.C.3
  • 69
    • 3242752040 scopus 로고    scopus 로고
    • + T cells and interferon gamma are essential for the disorder
    • DOI 10.1182/blood-2003-10-3413
    • Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 2004;104:735-743. (Pubitemid 38970567)
    • (2004) Blood , vol.104 , Issue.3 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3    Marrack, P.4
  • 70
    • 0034795745 scopus 로고    scopus 로고
    • Pathogenesis of haemophagocytic lymphohistiocytosis
    • DOI 10.1046/j.1365-2141.2001.02936.x
    • Arico M, Danesino C, Pende D, et al. Pathogenesis of haemophagocytic lymphohistiocytosis. Br J Haematol. 2001;114:761-769. (Pubitemid 32953731)
    • (2001) British Journal of Haematology , vol.114 , Issue.4 , pp. 761-769
    • Arico, M.1    Danesino, C.2    Pende, D.3    Moretta, L.4
  • 71
    • 1442274795 scopus 로고    scopus 로고
    • Pathogenesis of hemophagocytic syndrome (HPS)
    • DOI 10.1016/S1568-9972(03)00091-0, PII S1568997203000910
    • Larroche C, Mouthon L. Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev. 2004;3:69-75. (Pubitemid 38293367)
    • (2004) Autoimmunity Reviews , vol.3 , Issue.2 , pp. 69-75
    • Larroche, C.1    Mouthon, L.2
  • 72
    • 0043236325 scopus 로고    scopus 로고
    • Natural killer deficiency: A minor or major factor in the manifestation of hemophagocytic lymphohistiocytosis?
    • DOI 10.1097/00043426-200309000-00002
    • Schneider EM, Lorenz I, Walther P, et al. Natural killer deficiency: a minor or major factor in the manifestation of hemophagocytic lymphohistiocytosis? J Pediatr Hematol Oncol. 2003;25:680-683. (Pubitemid 37087502)
    • (2003) Journal of Pediatric Hematology/Oncology , vol.25 , Issue.9 , pp. 680-683
    • Schneider, E.M.1    Lorenz, I.2    Walther, P.3    Janka-Schaub, G.E.4
  • 73
    • 0029416957 scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death
    • Selleri C, Sato T, Anderson S, et al. Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death. J Cell Physiol. 1995; 165: 538-546.
    • (1995) J Cell Physiol , vol.165 , pp. 538-546
    • Selleri, C.1    Sato, T.2    Anderson, S.3
  • 74
    • 0043268709 scopus 로고    scopus 로고
    • Heme oxygenase-1: Unleashing the protective properties of heme
    • DOI 10.1016/S1471-4906(03)00181-9
    • Otterbein LE, Soares MP, Yamashita K, et al. Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol. 2003;24:449-455. (Pubitemid 36928103)
    • (2003) Trends in Immunology , vol.24 , Issue.8 , pp. 449-455
    • Otterbein, L.E.1    Soares, M.P.2    Yamashita, K.3    Bach, F.H.4
  • 75
    • 33845878531 scopus 로고    scopus 로고
    • Familial and acquired hemophagocytic lymphohistiocytosis
    • DOI 10.1007/s00431-006-0258-1
    • Janka GE. Familial and acquired hemophagocytic lymphohistiocytosis. Eur J Pediatr. 2007;166:95-109. (Pubitemid 46025500)
    • (2007) European Journal of Pediatrics , vol.166 , Issue.2 , pp. 95-109
    • Janka, G.E.1
  • 79
    • 3042793578 scopus 로고    scopus 로고
    • Linking albinism and immunity: The secrets of secretory lysosomes
    • DOI 10.1126/science.1095291
    • Stinchcombe J, Bossi G, Griffiths GM. Linking albinism and immunity: the secrets of secretory lysosomes. Science. 2004;305:55-59. (Pubitemid 38869367)
    • (2004) Science , vol.305 , Issue.5680 , pp. 55-59
    • Stinchcombe, J.1    Bossi, G.2    Giffiths, G.M.3
  • 81
    • 77649154766 scopus 로고    scopus 로고
    • Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations
    • Meeths M, Bryceson YT, Rudd E, et al. Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Pediatr Blood Cancer. 2010; 54: 563-572.
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 563-572
    • Meeths, M.1    Bryceson, Y.T.2    Rudd, E.3
  • 85
    • 0043234919 scopus 로고    scopus 로고
    • Epstein-Barr virus-associated haemophagocytic lymphohistiocytosis in Wiskott-Aldrich syndrome
    • DOI 10.1080/08035250310003631
    • Pasic S, Micic D, Kuzmanovic M. Epstein-Barr virus-associated haemophagocytic lymphohistiocytosis in Wiskott-Aldrich syndrome. Acta Paediatr. 2003;92:859-861. (Pubitemid 37098303)
    • (2003) Acta Paediatrica, International Journal of Paediatrics , vol.92 , Issue.7 , pp. 859-861
    • Pasic, S.1    Micic, D.2    Kuzmanovic, M.3
  • 86
    • 0032706071 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in a patient with deletion of 22q11.2
    • Arico M, Bettinelli A, Maccario R, et al. Hemophagocytic lymphohistiocytosis in a patient with deletion of 22q11.2. Am J Med Genet. 1999; 87: 329-330.
    • (1999) Am J Med Genet , vol.87 , pp. 329-330
    • Arico, M.1    Bettinelli, A.2    Maccario, R.3
  • 87
    • 0036238933 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for active Epstein-Barr virus-related lymphoproliferative disease and hemophagocytic lymphohistiocytosis in an infant with severe combined immunodeficiency syndrome
    • DOI 10.1038/sj/bmt/1703396
    • Schmid I, Reiter K, Schuster F, et al. Allogeneic bone marrow transplantation for active Epstein-Barr virus-related lymphoproliferative disease and hemophagocytic lymphohistiocytosis in an infant with severe combined immunodeficiency syndrome. Bone Marrow Transplant. 2002;29:519-521. (Pubitemid 34428722)
    • (2002) Bone Marrow Transplantation , vol.29 , Issue.6 , pp. 519-521
    • Schmid, I.1    Reiter, K.2    Schuster, F.3    Wintergerst, U.4    Meilbeck, R.5    Nicolai, T.6    Behloradsky, B.H.7    Stachel, D.K.8
  • 88
    • 0018656157 scopus 로고
    • Vitus-associated hemophagocytic syndrome. A benign histiocytic proliferation distinct from malignant histiocytosis
    • DOI 10.1002/1097-0142(197909)44:3<993::AID
    • Risdall RJ, McKenna RW, Nesbit ME, et al. Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer. 1979;44:993-1002. (Pubitemid 10242233)
    • (1979) Cancer , vol.44 , Issue.3 , pp. 993-1002
    • Risdall, R.J.1    McKenna, R.W.2    Nesbit, M.E.3
  • 89
    • 21144435788 scopus 로고    scopus 로고
    • A proportion of patients with lymphoma may harbor mutations of the perforin gene
    • Clementi R, Locatelli F, Dupre L, et al. A proportion of patients with lymphoma may harbor mutations of the perforin gene. Blood. 2005; 105: 4424-4428.
    • (2005) Blood , vol.105 , pp. 4424-4428
    • Clementi, R.1    Locatelli, F.2    Dupre, L.3
  • 91
    • 0742269908 scopus 로고    scopus 로고
    • Hemophagocytic syndrome in renal transplant recipients: Report of 17 cases and review of literature
    • DOI 10.1097/01.TP.0000107285.86939.37
    • Karras A, Thervet E, Legendre C. Hemophagocytic syndrome in renal transplant recipients: report of 17 cases and review of literature. Transplantation. 2004;77:238-243. (Pubitemid 38155753)
    • (2004) Transplantation , vol.77 , Issue.2 , pp. 238-243
    • Karras, A.1    Thervet, E.2    Legendre, C.3
  • 92
    • 67649211723 scopus 로고    scopus 로고
    • Hemophagocytic syndrome after hematopoietic stem cell transplantation: A prospective observational study
    • Abdelkefi A, Ben Jamil W, Torjman L, et al. Hemophagocytic syndrome after hematopoietic stem cell transplantation: a prospective observational study. Int J Hematol. 2009; 89: 368-373.
    • (2009) Int J Hematol , vol.89 , pp. 368-373
    • Abdelkefi, A.1    Ben Jamil, W.2    Torjman, L.3
  • 94
    • 0036900751 scopus 로고    scopus 로고
    • Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
    • DOI 10.1016/S1040-8428(02)00117-8, PII S1040842802001178
    • Imashuku S. Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Crit Rev Oncol Hematol. 2002;44:259-272. (Pubitemid 35435291)
    • (2002) Critical Reviews in Oncology/Hematology , vol.44 , Issue.3 , pp. 259-272
    • Imashuku, S.1
  • 95
    • 33645067966 scopus 로고    scopus 로고
    • Fatal HHV-8-associated hemophagocytic syndrome in an HIV-negative immunocompetent patient with plasmablastic variant of multicentric castleman disease (plasmablastic microlymphoma)
    • DOI 10.1097/01.pas.0000172293.59785.b4, PII 0000047820060100000018
    • Li CF, Ye H, Liu H, et al. Fatal HHV-8-associated hemophagocytic syndrome in an HIV-negative immunocompetent patient with plasmablastic variant of multicentric Castleman disease (plasmablastic microlymphoma). Am J Surg Pathol. 2006;30:123-127. (Pubitemid 43740219)
    • (2006) American Journal of Surgical Pathology , vol.30 , Issue.1 , pp. 123-127
    • Li, C.-F.1    Ye, H.2    Liu, H.3    Du, M.-Q.4    Chuang, S.-S.5
  • 97
    • 22144461334 scopus 로고    scopus 로고
    • Acute liver failure and severe hemophagocytosis secondary to parvovirus B19 infection
    • Dutta U, Mittal S, Ratho RK, et al. Acute liver failure and severe hemophagocytosis secondary to parvovirus B19 infection. Indian J Gastroenterol. 2005;24:118-119. (Pubitemid 40980039)
    • (2005) Indian Journal of Gastroenterology , vol.24 , Issue.3 , pp. 118-119
    • Dutta, U.1    Mittal, S.2    Ratho, R.K.3    Das, A.4
  • 99
    • 10044227130 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: An unusual initial presentation of acute HIV infection
    • Sun HY, Chen MY, Fang CT, et al. Hemophagocytic lymphohistiocytosis: an unusual initial presentation of acute HIV infection. J Acquir Immune Defic Syndr. 2004; 37: 1539-1540.
    • (2004) J Acquir Immune Defic Syndr , vol.37 , pp. 1539-1540
    • Sun, H.Y.1    Chen, M.Y.2    Fang, C.T.3
  • 100
    • 0022411986 scopus 로고
    • Acquired immunodeficiency syndrome. Clinicopathologic study of 56 autopsies
    • Niedt GW, Schinella RA. Acquired immunodeficiency syndrome: clinicopathologic study of 56 autopsies. Arch Pathol Lab Med. 1985;109:727-734. (Pubitemid 16237468)
    • (1985) Archives of Pathology and Laboratory Medicine , vol.109 , Issue.8 , pp. 727-734
    • Niedt, G.W.1    Schinella, R.A.2
  • 102
    • 0031926347 scopus 로고    scopus 로고
    • Infection- and malignancy-associated hemophagocytic syndromes: Secondary hemophagocytic lymphohistiocytosis
    • DOI 10.1016/S0889-8588(05)70521-9
    • Janka G, Imashuku S, Elinder G, et al. Infection- and malignancy-associated hemophagocytic syndromes: secondary hemophagocytic lymphohistiocytosis. Hematol Oncol Clin North Am. 1998;12:435-444. (Pubitemid 28175891)
    • (1998) Hematology/Oncology Clinics of North America , vol.12 , Issue.2 , pp. 435-444
    • Janka, G.1    Imashuku, S.2    Elinder, G.3    Schneider, M.4    Henter, J.-I.5
  • 104
    • 0031599846 scopus 로고    scopus 로고
    • A child case of haemophagocytic syndrome associated with cryptococcal meningoencephalitis
    • Numata K, Tsutsumi H, Wakai S, et al. A child case of haemophagocytic syndrome associated with cryptococcal meningoencephalitis. J Infect. 1998;36:118-119. (Pubitemid 128645639)
    • (1998) Journal of Infection , vol.36 , Issue.1 , pp. 118-119
    • Numata, K.1    Tsutsumi, H.2    Wakai, S.3    Tachi, N.4    Chiba, S.5
  • 106
    • 77952895495 scopus 로고    scopus 로고
    • Reactive haemophagocytic syndrome in 58 HIV-1-infected patients: Clinical features, underlying diseases and prognosis
    • Fardet L, Lambotte O, Meynard JL, et al. Reactive haemophagocytic syndrome in 58 HIV-1-infected patients: clinical features, underlying diseases and prognosis. AIDS. 2010; 24: 1299-1306.
    • (2010) AIDS , vol.24 , pp. 1299-1306
    • Fardet, L.1    Lambotte, O.2    Meynard, J.L.3
  • 110
    • 0032516280 scopus 로고    scopus 로고
    • Epstein-Barr virus in action in vivo
    • DOI 10.1056/NEJM199805143382011
    • Rickinson AB. Epstein-Barr virus in action in vivo. N Engl J Med. 1998;338:1461-1463. (Pubitemid 28221990)
    • (1998) New England Journal of Medicine , vol.338 , Issue.20 , pp. 1461-1463
    • Rickinson, A.B.1
  • 112
    • 0028221477 scopus 로고
    • Epstein-Barr virus (EBV) infects T lymphocytes in childhood EBV-associated hemophagocytic syndrome in Taiwan
    • Su IJ, Chen RL, Lin DT, et al. Epstein-Barr virus (EBV) infects T lymphocytes in childhood EBV-associated hemophagocytic syndrome in Taiwan. Am J Pathol. 1994; 144: 1219-1225.
    • (1994) Am J Pathol , vol.144 , pp. 1219-1225
    • Su, I.J.1    Chen, R.L.2    Lin, D.T.3
  • 113
    • 0035885961 scopus 로고    scopus 로고
    • Differential cellular targets of Epstein-Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection
    • Kasahara Y, Yachie A, Takei K, et al. Differential cellular targets of Epstein-Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection. Blood. 2001; 98: 1882-1888.
    • (2001) Blood , vol.98 , pp. 1882-1888
    • Kasahara, Y.1    Yachie, A.2    Takei, K.3
  • 114
    • 0036898277 scopus 로고    scopus 로고
    • Cell type specific infection of Epstein-Barr virus (EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection
    • DOI 10.1016/S1040-8428(02)00119-1, PII S1040842802001191
    • Kasahara Y, Yachie A. Cell type specific infection of Epstein-Barr virus (EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection. Crit Rev Oncol Hematol. 2002;44:283-294. (Pubitemid 35435293)
    • (2002) Critical Reviews in Oncology/Hematology , vol.44 , Issue.3 , pp. 283-294
    • Kasahara, Y.1    Yachie, A.2
  • 115
    • 0026640540 scopus 로고
    • Detection of clonal Epstein-Barr virus in malignant proliferation of peripheral blood CD3+ CD8+ T cells
    • Chan LC, Srivastava G, Pittaluga S, et al. Detection of clonal Epstein-Barr virus in malignant proliferation of peripheral blood CD3+ CD8+ T cells. Leukemia. 1992; 6: 952-956.
    • (1992) Leukemia , vol.6 , pp. 952-956
    • Chan, L.C.1    Srivastava, G.2    Pittaluga, S.3
  • 117
    • 0031438953 scopus 로고    scopus 로고
    • Clonal karyotype abnormalities in EBV-associated hemophagocytic syndrome
    • Chen JS, Tzeng CC, Tsao CJ, et al. Clonal karyotype abnormalities in EBV-associated hemophagocytic syndrome. Haematologica. 1997; 82: 572-576.
    • (1997) Haematologica , vol.82 , pp. 572-576
    • Chen, J.S.1    Tzeng, C.C.2    Tsao, C.J.3
  • 118
    • 0030770948 scopus 로고    scopus 로고
    • Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome
    • Lay JD, Tsao CJ, Chen JY, et al. Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest. 1997; 100: 1969-1979.
    • (1997) J Clin Invest , vol.100 , pp. 1969-1979
    • Lay, J.D.1    Tsao, C.J.2    Chen, J.Y.3
  • 119
    • 0031203664 scopus 로고    scopus 로고
    • EBV-elicited familial hemophagocytic lymphohistiocytosis
    • Cho HS, Park YN, Lyu CJ, et al. EBV-elicited familial hemophagocytic lymphohistiocytosis. Yonsei Med J. 1997; 38: 245-248.
    • (1997) Yonsei Med J , vol.38 , pp. 245-248
    • Cho, H.S.1    Park, Y.N.2    Lyu, C.J.3
  • 122
    • 2642617808 scopus 로고    scopus 로고
    • Epstein-Barr virus-infected B cells of males with the X-linked lymphoproliferative syndrome stimulate and are susceptible to T-cell-mediated lysis
    • DOI 10.1002/(SICI)1097-0215(19980529)76:5<694::AID
    • Jager M, Benninger-Doring G, Prang N, et al. Epstein-Barr virus-infected B cells of males with the X-linked lymphoproliferative syndrome stimulate and are susceptible to T-cell-mediated lysis. Int J Cancer. 1998;76:694-701. (Pubitemid 28243943)
    • (1998) International Journal of Cancer , vol.76 , Issue.5 , pp. 694-701
    • Jager, M.1    Benninger-Doring, G.2    Prang, N.3    Sylla, B.S.4    Laumbacher, B.5    Wank, R.6    Wolf, H.7    Schwarzmann, F.8
  • 124
    • 27644592071 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome
    • Chuang HC, Lay JD, Hsieh WC, et al. Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Blood. 2005; 106: 3090-3096.
    • (2005) Blood , vol.106 , pp. 3090-3096
    • Chuang, H.C.1    Lay, J.D.2    Hsieh, W.C.3
  • 126
    • 19844363975 scopus 로고    scopus 로고
    • Small cell lung cancer presenting as hemophagocytic syndrome
    • in Japanese
    • Tatsuta H, Hoso T, Takagi T, et al. Small cell lung cancer presenting as hemophagocytic syndrome [in Japanese]. Nihon Naika Gakkai Zasshi. 2005; 94: 756-758.
    • (2005) Nihon Naika Gakkai Zasshi , vol.94 , pp. 756-758
    • Tatsuta, H.1    Hoso, T.2    Takagi, T.3
  • 127
    • 0036719352 scopus 로고    scopus 로고
    • The hemophagocytic syndrome in prostate cancer revealed by disseminated carcinomatosis of the bone marrow
    • Koizumi K, Haseyama Y, Machino R, et al. The hemophagocytic syndrome in prostate cancer revealed by disseminated carcinomatosis of the bone marrow. J Urol. 2002; 168: 1101-1102.
    • (2002) J Urol , vol.168 , pp. 1101-1102
    • Koizumi, K.1    Haseyama, Y.2    Machino, R.3
  • 128
    • 48749102603 scopus 로고    scopus 로고
    • Hodgkin lymphoma-associated hemophagocytic syndrome: A disorder strongly correlated with Epstein-Barr virus
    • Menard F, Besson C, Rince P, et al. Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008; 47: 531-534.
    • (2008) Clin Infect Dis , vol.47 , pp. 531-534
    • Menard, F.1    Besson, C.2    Rince, P.3
  • 129
    • 79955742644 scopus 로고    scopus 로고
    • Haemophagocytic lymphohistiocytosis is a recurrent and specific complication of acute erythroid leukaemia
    • Yamazaki S, Nakamura F, Nasu R, et al. Haemophagocytic lymphohistiocytosis is a recurrent and specific complication of acute erythroid leukaemia. Br J Haematol. 2011; 153: 669-672.
    • (2011) Br J Haematol , vol.153 , pp. 669-672
    • Yamazaki, S.1    Nakamura, F.2    Nasu, R.3
  • 130
    • 38049054790 scopus 로고    scopus 로고
    • New functions for an iron storage protein: The role of ferritin in immunity and autoimmunity
    • Recalcati S, Invernizzi P, Arosio P, et al. New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun. 2008; 30: 84-89.
    • (2008) J Autoimmun , vol.30 , pp. 84-89
    • Recalcati, S.1    Invernizzi, P.2    Arosio, P.3
  • 131
    • 34548359264 scopus 로고    scopus 로고
    • Recognition and management of macrophage activation syndrome in juvenile arthritis
    • DOI 10.1097/BOR.0b013e32825a6a79, PII 0000228120070900000014
    • Kelly A, Ramanan AV. Recognition and management of macrophage activation syndrome in juvenile arthritis. Curr Opin Rheumatol. 2007;19:477-481. (Pubitemid 47344241)
    • (2007) Current Opinion in Rheumatology , vol.19 , Issue.5 , pp. 477-481
    • Kelly, A.1    Ramanan, A.V.2
  • 132
    • 61549122395 scopus 로고    scopus 로고
    • Hemophagocytic syndrome in elderly patients with underlying autoimmune diseases
    • Tabata R, Tabata C, Terada M, et al. Hemophagocytic syndrome in elderly patients with underlying autoimmune diseases. Clin Rheumatol. 2009; 28: 461-464.
    • (2009) Clin Rheumatol , vol.28 , pp. 461-464
    • Tabata, R.1    Tabata, C.2    Terada, M.3
  • 135
  • 137
    • 0036786375 scopus 로고    scopus 로고
    • Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
    • Henter JI, Samuelsson-Horne A, Arico M, et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002; 100: 2367-2373.
    • (2002) Blood , vol.100 , pp. 2367-2373
    • Henter, J.I.1    Samuelsson-Horne, A.2    Arico, M.3
  • 139
    • 80053483077 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: A potentially underrecognized association with systemic inflammatory response syndrome, severe sepsis, and septic shock in adults
    • Raschke RA, Garcia-Orr R. Hemophagocytic lymphohistiocytosis: a potentially underrecognized association with systemic inflammatory response syndrome, severe sepsis, and septic shock in adults. Chest. 2011; 140: 933-938.
    • (2011) Chest , vol.140 , pp. 933-938
    • Raschke, R.A.1    Garcia-Orr, R.2


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