High Level of Perforin Expression is Required for Effective Correction of Hemophagocytic Lymphohistiocytosis

Human Gene Therapy

Volumn 27, Issue 10, 2016, Pages 847-859

  Tiwari, Swati ^a,b   Hontz, Adrianne ^c   Terrell, Catherine E ^b   Arumugam, Paritha ^b   Carmo, Marlene ^d   Risma, Kimberly ^c   Jordan, Michael ^c   Malik, Punam ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c CCHMC   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; LENTIVIRUS VECTOR; MICRORNA 126; PERFORIN; PHOSPHOGLYCERATE KINASE; MICRORNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; ENHANCER REGION; GENETIC ENGINEERING; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL; HEMOPHAGOCYTIC SYNDROME; HUMAN; HUMAN CELL; LONG TERMINAL REPEAT; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOLONEY MURINE LEUKEMIA VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; SARCOMA VIRUS; VIRAL CLEARANCE; VIRAL GENE THERAPY; ANIMAL; CELL PROLIFERATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE THERAPY; GENE VECTOR; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INFLAMMATION; LENTIVIRUS; METABOLISM; MUTATION; PATHOLOGY; THERAPEUTIC USE;

ANIMALS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENETIC THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFLAMMATION; KILLER CELLS, NATURAL; LENTIVIRUS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MICE; MICRORNAS; MUTATION; PERFORIN;

EID: 84989271383     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2016.065     Document Type: Article

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