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Volumn 37, Issue 4, 2019, Pages 416-427

Erratum: Strategies for Engineering Natural Product Biosynthesis in Fungi: (Trends in Biotechnology (2019) 37(4) (416–427), (S0167779918302567), (10.1016/j.tibtech.2018.09.003));Strategies for Engineering Natural Product Biosynthesis in Fungi

Author keywords

biomolecular engineering; biotechnology; combinatorial biosynthesis; drug discovery; fungi; natural products

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; BIOTECHNOLOGY; DRUG PRODUCTS; ENZYMES; FUNGI;

EID: 85054430369     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2019.03.014     Document Type: Erratum
Times cited : (65)

References (87)
  • 1
    • 84962367258 scopus 로고    scopus 로고
    • Natural products as sources of new drugs from 1981 to 2014
    • Newman, D.J., Cragg, G.M., Natural products as sources of new drugs from 1981 to 2014. J. Nat. Prod. 79 (2016), 629–661.
    • (2016) J. Nat. Prod. , vol.79 , pp. 629-661
    • Newman, D.J.1    Cragg, G.M.2
  • 2
    • 85007333048 scopus 로고    scopus 로고
    • Exploitation of fungal biodiversity for discovery of novel antibiotics
    • Karwehl, S., Stadler, M., Exploitation of fungal biodiversity for discovery of novel antibiotics. Curr. Top. Microbiol. Immunol. 398 (2017), 303–338.
    • (2017) Curr. Top. Microbiol. Immunol. , vol.398 , pp. 303-338
    • Karwehl, S.1    Stadler, M.2
  • 3
    • 85011693564 scopus 로고    scopus 로고
    • Biologically active secondary metabolites from the fungi
    • Bills, G.F., Gloer, J.B., Biologically active secondary metabolites from the fungi. Microbiol. Spectr., 4, 2016, 10.1128/microbiolspec.FUNK-0009-2016.
    • (2016) Microbiol. Spectr. , vol.4
    • Bills, G.F.1    Gloer, J.B.2
  • 4
    • 84957068722 scopus 로고    scopus 로고
    • Microbial metabolomics in open microscale platforms
    • 10610
    • Barkal, J., et al. Microbial metabolomics in open microscale platforms. Nat. Commun., 7, 2016 10610.
    • (2016) Nat. Commun. , vol.7
    • Barkal, J.1
  • 5
    • 84971283836 scopus 로고    scopus 로고
    • Counting on natural products for drug design
    • Rodrigues, T., et al. Counting on natural products for drug design. Nat. Chem. 8 (2016), 531–541.
    • (2016) Nat. Chem. , vol.8 , pp. 531-541
    • Rodrigues, T.1
  • 6
    • 85026802919 scopus 로고    scopus 로고
    • Fungal diversity revisited: 2.2 to 3.8 million species
    • Hawksworth, D.L., Lücking, R., Fungal diversity revisited: 2.2 to 3.8 million species. Microbiol. Spectr., 5, 2017, 10.1128/microbiolspec.FUNK-0052-2016.
    • (2017) Microbiol. Spectr. , vol.5
    • Hawksworth, D.L.1    Lücking, R.2
  • 7
    • 84891805647 scopus 로고    scopus 로고
    • The genome portal of the Department of Energy Joint Genome Institute: 2014 updates
    • Nordberg, H., et al. The genome portal of the Department of Energy Joint Genome Institute: 2014 updates. Nucleic Acids Res. 42 (2014), D26–D31.
    • (2014) Nucleic Acids Res. , vol.42 , pp. D26-D31
    • Nordberg, H.1
  • 8
    • 85054431787 scopus 로고    scopus 로고
    • FungiDB: an integrated bioinformatic resource for fungi and oomycetes
    • Basenko, E.Y., et al. FungiDB: an integrated bioinformatic resource for fungi and oomycetes. J. Fungi, 4, 2018, 39.
    • (2018) J. Fungi , vol.4 , pp. 39
    • Basenko, E.Y.1
  • 9
    • 84960087369 scopus 로고    scopus 로고
    • Computational strategies for genome-based natural product discovery and engineering in fungi
    • Van der Lee, T.A.J., Medema, M.H., Computational strategies for genome-based natural product discovery and engineering in fungi. Fungal Genet. Biol. 89 (2016), 29–36.
    • (2016) Fungal Genet. Biol. , vol.89 , pp. 29-36
    • Van der Lee, T.A.J.1    Medema, M.H.2
  • 10
    • 84871997235 scopus 로고    scopus 로고
    • Accurate prediction of secondary metabolite gene clusters in filamentous fungi
    • Andersen, M.R., et al. Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), E99–E107.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. E99-E107
    • Andersen, M.R.1
  • 11
    • 84924073137 scopus 로고    scopus 로고
    • Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products
    • Wang, X., et al. Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products. BMC Genomics, 16, 2015, 28.
    • (2015) BMC Genomics , vol.16 , pp. 28
    • Wang, X.1
  • 12
    • 84880028198 scopus 로고    scopus 로고
    • Structurally diverse chaetophenol productions induced by chemically mediated epigenetic manipulation of fungal gene expression
    • Asai, T., et al. Structurally diverse chaetophenol productions induced by chemically mediated epigenetic manipulation of fungal gene expression. Org. Lett. 15 (2013), 3346–3349.
    • (2013) Org. Lett. , vol.15 , pp. 3346-3349
    • Asai, T.1
  • 13
    • 84930257321 scopus 로고    scopus 로고
    • Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products
    • Mao, X.M., et al. Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products. Angew. Chem. Int. Ed. Engl. 54 (2015), 7592–7596.
    • (2015) Angew. Chem. Int. Ed. Engl. , vol.54 , pp. 7592-7596
    • Mao, X.M.1
  • 14
    • 84935007874 scopus 로고    scopus 로고
    • Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbation
    • Albright, J.C., et al. Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbation. ACS Chem. Biol. 10 (2015), 1535–1541.
    • (2015) ACS Chem. Biol. , vol.10 , pp. 1535-1541
    • Albright, J.C.1
  • 15
    • 84983319779 scopus 로고    scopus 로고
    • New aspercryptins, lipopeptide natural products revealed by HDAC inhibition in Aspergillus nidulans
    • Henke, M.T., et al. New aspercryptins, lipopeptide natural products revealed by HDAC inhibition in Aspergillus nidulans. ACS Chem. Biol. 11 (2016), 2117–2123.
    • (2016) ACS Chem. Biol. , vol.11 , pp. 2117-2123
    • Henke, M.T.1
  • 16
    • 84955504294 scopus 로고    scopus 로고
    • Development of genetic dereplication strains in Aspergillus nidulans results in the discovery of aspercryptin
    • Chiang, Y.M., et al. Development of genetic dereplication strains in Aspergillus nidulans results in the discovery of aspercryptin. Angew. Chem. Int. Ed. Engl. 55 (2016), 1662–1665.
    • (2016) Angew. Chem. Int. Ed. Engl. , vol.55 , pp. 1662-1665
    • Chiang, Y.M.1
  • 17
    • 85002788680 scopus 로고    scopus 로고
    • Discovery of McrA, a master regulator of Aspergillus secondary metabolism
    • Oakley, C.E., et al. Discovery of McrA, a master regulator of Aspergillus secondary metabolism. Mol. Microbiol. 103 (2017), 347–365.
    • (2017) Mol. Microbiol. , vol.103 , pp. 347-365
    • Oakley, C.E.1
  • 18
    • 84943523181 scopus 로고    scopus 로고
    • Regulation of secondary metabolite production in the fungal tomato pathogen Cladosporium fulvum
    • Griffiths, S., et al. Regulation of secondary metabolite production in the fungal tomato pathogen Cladosporium fulvum. Fungal Genet. Biol. 84 (2015), 52–61.
    • (2015) Fungal Genet. Biol. , vol.84 , pp. 52-61
    • Griffiths, S.1
  • 19
    • 85018504230 scopus 로고    scopus 로고
    • Collaborative biosynthesis of maleimide- and succinimide-containing natural products by fungal polyketide megasynthases
    • Sato, M., et al. Collaborative biosynthesis of maleimide- and succinimide-containing natural products by fungal polyketide megasynthases. J. Am. Chem. Soc. 139 (2017), 5317–5320.
    • (2017) J. Am. Chem. Soc. , vol.139 , pp. 5317-5320
    • Sato, M.1
  • 20
    • 84963558322 scopus 로고    scopus 로고
    • Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus
    • Baccile, J.A., et al. Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. Nat. Chem. Biol. 12 (2016), 419–424.
    • (2016) Nat. Chem. Biol. , vol.12 , pp. 419-424
    • Baccile, J.A.1
  • 21
    • 85031782586 scopus 로고    scopus 로고
    • Fungal cordyceptin biosynthesis is coupled with the production of the safeguard molecule pentostatin
    • Xia, Y., et al. Fungal cordyceptin biosynthesis is coupled with the production of the safeguard molecule pentostatin. Cell Chem. Biol. 24 (2017), 1479–1489.
    • (2017) Cell Chem. Biol. , vol.24 , pp. 1479-1489
    • Xia, Y.1
  • 22
    • 85008191267 scopus 로고    scopus 로고
    • Self-excising Cre/mutant lox marker recycling system for multiple gene integrations and consecutive gene deletions in Aspergillus oryzae
    • Zhang, S., et al. Self-excising Cre/mutant lox marker recycling system for multiple gene integrations and consecutive gene deletions in Aspergillus oryzae. J. Biosci. Bioeng. 123 (2016), 403–411.
    • (2016) J. Biosci. Bioeng. , vol.123 , pp. 403-411
    • Zhang, S.1
  • 23
    • 84983287438 scopus 로고    scopus 로고
    • Resistance gene-guided genome mining: serial promoter exchanges in Aspergillus nidulans reveal the biosynthetic pathway for fellutamide B, a proteasome inhibitor
    • Yeh, H.H., et al. Resistance gene-guided genome mining: serial promoter exchanges in Aspergillus nidulans reveal the biosynthetic pathway for fellutamide B, a proteasome inhibitor. ACS Chem. Biol. 11 (2016), 2275–2284.
    • (2016) ACS Chem. Biol. , vol.11 , pp. 2275-2284
    • Yeh, H.H.1
  • 24
    • 84929955092 scopus 로고    scopus 로고
    • Tailor-made TALEN system for highly efficient targeted gene replacement in the rice blast fungus
    • Arazoe, T., et al. Tailor-made TALEN system for highly efficient targeted gene replacement in the rice blast fungus. Biotechnol. Bioeng. 112 (2015), 1335–1342.
    • (2015) Biotechnol. Bioeng. , vol.112 , pp. 1335-1342
    • Arazoe, T.1
  • 25
    • 85001931443 scopus 로고    scopus 로고
    • Detailed analysis of targeted gene mutations caused by the platinum-fungal TALENs in Aspergillus oryzae RIB40 strain and a ligD disruptant
    • Mizutani, O., et al. Detailed analysis of targeted gene mutations caused by the platinum-fungal TALENs in Aspergillus oryzae RIB40 strain and a ligD disruptant. J. Biosci. Bioeng. 123 (2017), 287–293.
    • (2017) J. Biosci. Bioeng. , vol.123 , pp. 287-293
    • Mizutani, O.1
  • 26
    • 84899810872 scopus 로고    scopus 로고
    • Development of an unmarked gene deletion system for the filamentous fungi Aspergillus niger and Talaromyces versatilis
    • Delmas, S., et al. Development of an unmarked gene deletion system for the filamentous fungi Aspergillus niger and Talaromyces versatilis. Appl. Environ. Microbiol. 80 (2014), 3484–3487.
    • (2014) Appl. Environ. Microbiol. , vol.80 , pp. 3484-3487
    • Delmas, S.1
  • 27
    • 84950279555 scopus 로고    scopus 로고
    • Class of cyclic ribosomal peptide synthetic genes in filamentous fungi
    • Nagano, N., et al. Class of cyclic ribosomal peptide synthetic genes in filamentous fungi. Fungal Genet. Biol. 86 (2016), 58–70.
    • (2016) Fungal Genet. Biol. , vol.86 , pp. 58-70
    • Nagano, N.1
  • 28
    • 84969872558 scopus 로고    scopus 로고
    • Unveiling the biosynthetic pathway of the ribosomally synthesized and post-translationally modified peptide ustiloxin B in filamentous fungi
    • Ye, Y., et al. Unveiling the biosynthetic pathway of the ribosomally synthesized and post-translationally modified peptide ustiloxin B in filamentous fungi. Angew. Chem. Int. Ed. Engl. 55 (2016), 8072–8075.
    • (2016) Angew. Chem. Int. Ed. Engl. , vol.55 , pp. 8072-8075
    • Ye, Y.1
  • 29
    • 85016411346 scopus 로고    scopus 로고
    • A cascade of redox reactions generates complexity in the biosynthesis of the protein phosphatase-2 inhibitor rubratoxin A
    • Bai, J., et al. A cascade of redox reactions generates complexity in the biosynthesis of the protein phosphatase-2 inhibitor rubratoxin A. Angew. Chem. Int. Ed. Engl. 56 (2017), 4782–4786.
    • (2017) Angew. Chem. Int. Ed. Engl. , vol.56 , pp. 4782-4786
    • Bai, J.1
  • 30
    • 84915820926 scopus 로고    scopus 로고
    • Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion
    • Chankhamjon, P., et al. Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion. Angew. Chem. Int. Ed. Engl. 53 (2014), 13409–13413.
    • (2014) Angew. Chem. Int. Ed. Engl. , vol.53 , pp. 13409-13413
    • Chankhamjon, P.1
  • 31
    • 84964408905 scopus 로고    scopus 로고
    • Molecular characterization of the cercosporin biosynthetic pathway in the fungal plant pathogen Cercospora nicotianae
    • Newman, A.G., Townsend, C.A., Molecular characterization of the cercosporin biosynthetic pathway in the fungal plant pathogen Cercospora nicotianae. J. Am. Chem. Soc. 138 (2016), 4219–4228.
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 4219-4228
    • Newman, A.G.1    Townsend, C.A.2
  • 32
    • 85028968956 scopus 로고    scopus 로고
    • CRISPR/Cas9-based genome editing of the filamentous fungi: the state of the art
    • Shi, T.-Q., et al. CRISPR/Cas9-based genome editing of the filamentous fungi: the state of the art. Appl. Microbiol. Biotechnol. 101 (2017), 7435–7443.
    • (2017) Appl. Microbiol. Biotechnol. , vol.101 , pp. 7435-7443
    • Shi, T.-Q.1
  • 33
    • 85027979396 scopus 로고    scopus 로고
    • Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR–Cas9 technology
    • Zheng, Y.-M., et al. Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR–Cas9 technology. Sci. Rep., 7, 2017, 9250.
    • (2017) Sci. Rep. , vol.7 , pp. 9250
    • Zheng, Y.-M.1
  • 34
    • 85008675879 scopus 로고    scopus 로고
    • Genes linked to production of secondary metabolites in Talaromyces atroroseus revealed using CRISPR–Cas9
    • Nielsen, M.L., et al. Genes linked to production of secondary metabolites in Talaromyces atroroseus revealed using CRISPR–Cas9. PLoS One, 12, 2017, e0169712.
    • (2017) PLoS One , vol.12
    • Nielsen, M.L.1
  • 35
    • 85012831291 scopus 로고    scopus 로고
    • Functional reconstitution of a fungal natural product gene cluster by advanced genome editing
    • Weber, J., et al. Functional reconstitution of a fungal natural product gene cluster by advanced genome editing. ACS Synth. Biol. 6 (2016), 62–68.
    • (2016) ACS Synth. Biol. , vol.6 , pp. 62-68
    • Weber, J.1
  • 36
    • 84965104303 scopus 로고    scopus 로고
    • Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production
    • 25202
    • Bailey, A.M., et al. Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production. Sci. Rep., 6, 2016 25202.
    • (2016) Sci. Rep. , vol.6
    • Bailey, A.M.1
  • 37
    • 85060537853 scopus 로고    scopus 로고
    • Antibacterial properties and clinical potential of pleuromutilins
    • Published online July 6, 2018
    • Goethe, O., et al. Antibacterial properties and clinical potential of pleuromutilins. Nat. Prod. Rep., 2018, 10.1039/C8NP00042E Published online July 6, 2018.
    • (2018) Nat. Prod. Rep.
    • Goethe, O.1
  • 38
    • 85036498549 scopus 로고    scopus 로고
    • Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives
    • Alberti, F., et al. Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives. Nat. Commun., 8, 2017, 1831.
    • (2017) Nat. Commun. , vol.8 , pp. 1831
    • Alberti, F.1
  • 39
    • 85045733334 scopus 로고    scopus 로고
    • HEx: a heterologous expression platform for the discovery of fungal natural products
    • Harvey, C.J.B., et al. HEx: a heterologous expression platform for the discovery of fungal natural products. Sci. Adv., 4, 2018, 5459.
    • (2018) Sci. Adv. , vol.4 , pp. 5459
    • Harvey, C.J.B.1
  • 40
    • 85028586511 scopus 로고    scopus 로고
    • A scalable platform to identify fungal secondary metabolites and their gene clusters
    • Clevenger, K.D., et al. A scalable platform to identify fungal secondary metabolites and their gene clusters. Nat. Chem. Biol. 13 (2017), 895–901.
    • (2017) Nat. Chem. Biol. , vol.13 , pp. 895-901
    • Clevenger, K.D.1
  • 41
    • 85048385824 scopus 로고    scopus 로고
    • Interrogation of benzomalvin biosynthesis using FAC-MS: discovery of a benzodiazepine synthase activity
    • Clevenger, K.D., et al. Interrogation of benzomalvin biosynthesis using FAC-MS: discovery of a benzodiazepine synthase activity. Biochemistry 57 (2018), 3237–3243.
    • (2018) Biochemistry , vol.57 , pp. 3237-3243
    • Clevenger, K.D.1
  • 42
    • 84927169379 scopus 로고    scopus 로고
    • A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster
    • Gressler, M., et al. A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster. Front. Microbiol., 6, 2015, 184.
    • (2015) Front. Microbiol. , vol.6 , pp. 184
    • Gressler, M.1
  • 43
    • 84929590050 scopus 로고    scopus 로고
    • Native promoter strategy for high-yielding synthesis and engineering of fungal secondary metabolites
    • Kakule, T.B., et al. Native promoter strategy for high-yielding synthesis and engineering of fungal secondary metabolites. ACS Synth. Biol. 4 (2015), 625–633.
    • (2015) ACS Synth. Biol. , vol.4 , pp. 625-633
    • Kakule, T.B.1
  • 44
    • 84958124345 scopus 로고    scopus 로고
    • Production of new cladosporin analogues by reconstitution of the polyketide synthases responsible for the biosynthesis of this antimalarial agent
    • Cochrane, R.V.K., et al. Production of new cladosporin analogues by reconstitution of the polyketide synthases responsible for the biosynthesis of this antimalarial agent. Angew. Chem. Int. Ed. Engl. 55 (2016), 664–668.
    • (2016) Angew. Chem. Int. Ed. Engl. , vol.55 , pp. 664-668
    • Cochrane, R.V.K.1
  • 45
    • 84934993507 scopus 로고    scopus 로고
    • Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksA
    • Huitt-Roehl, C.R., et al. Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksA. ACS Chem. Biol. 10 (2015), 1443–1449.
    • (2015) ACS Chem. Biol. , vol.10 , pp. 1443-1449
    • Huitt-Roehl, C.R.1
  • 46
    • 84939811853 scopus 로고    scopus 로고
    • Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides
    • Asai, T., et al. Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides. Nat. Chem. 7 (2015), 737–743.
    • (2015) Nat. Chem. , vol.7 , pp. 737-743
    • Asai, T.1
  • 47
    • 84953432269 scopus 로고    scopus 로고
    • Discovery of unclustered fungal indole diterpene biosynthetic pathways through combinatorial pathway reassembly in engineered yeast
    • Tang, M.C., et al. Discovery of unclustered fungal indole diterpene biosynthetic pathways through combinatorial pathway reassembly in engineered yeast. J. Am. Chem. Soc. 137 (2015), 13724–13727.
    • (2015) J. Am. Chem. Soc. , vol.137 , pp. 13724-13727
    • Tang, M.C.1
  • 48
    • 85047938457 scopus 로고    scopus 로고
    • Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis
    • Xie, L., et al. Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis. Proc. Natl. Acad. Sci. U. S. A. 115 (2018), E4980–E4989.
    • (2018) Proc. Natl. Acad. Sci. U. S. A. , vol.115 , pp. E4980-E4989
    • Xie, L.1
  • 49
    • 84924189921 scopus 로고    scopus 로고
    • Single-step fermentative production of the cholesterol lowering drug pravastatin via reprogramming of Penicillium chrysogenum
    • McLean, K.J., et al. Single-step fermentative production of the cholesterol lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 2847–2852.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , pp. 2847-2852
    • McLean, K.J.1
  • 50
    • 85020893472 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of (+)-daurichromenic acid and its halogenated analogue
    • Okada, M., et al. Combinatorial biosynthesis of (+)-daurichromenic acid and its halogenated analogue. Org. Lett. 19 (2017), 3183–3186.
    • (2017) Org. Lett. , vol.19 , pp. 3183-3186
    • Okada, M.1
  • 51
    • 85029417697 scopus 로고    scopus 로고
    • RadH: a versatile halogenase for integration into synthetic pathways
    • Menon, B.R.K., et al. RadH: a versatile halogenase for integration into synthetic pathways. Angew. Chem. Int. Ed. Engl. 56 (2017), 11841–11845.
    • (2017) Angew. Chem. Int. Ed. Engl. , vol.56 , pp. 11841-11845
    • Menon, B.R.K.1
  • 52
    • 84905443683 scopus 로고    scopus 로고
    • Improvement of Aspergillus nidulans penicillin production by targeting AcvA to peroxisomes
    • Herr, A., Fischer, R., Improvement of Aspergillus nidulans penicillin production by targeting AcvA to peroxisomes. Metab. Eng. 25 (2014), 131–139.
    • (2014) Metab. Eng. , vol.25 , pp. 131-139
    • Herr, A.1    Fischer, R.2
  • 53
    • 84941628753 scopus 로고    scopus 로고
    • Spatial regulation of a common precursor from two distinct genes generates metabolite diversity
    • Guo, C.J., et al. Spatial regulation of a common precursor from two distinct genes generates metabolite diversity. Chem. Sci., 6, 2015, 5913.
    • (2015) Chem. Sci. , vol.6 , pp. 5913
    • Guo, C.J.1
  • 54
    • 84906672709 scopus 로고    scopus 로고
    • Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
    • Xu, Y., et al. Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 12354–12359.
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 12354-12359
    • Xu, Y.1
  • 55
    • 84961837656 scopus 로고    scopus 로고
    • Diversity-oriented combinatorial biosynthesis of hybrid polyketide scaffolds from azaphilone and benzenediol lactone biosynthons
    • Bai, J., et al. Diversity-oriented combinatorial biosynthesis of hybrid polyketide scaffolds from azaphilone and benzenediol lactone biosynthons. Org. Lett. 18 (2016), 1262–1265.
    • (2016) Org. Lett. , vol.18 , pp. 1262-1265
    • Bai, J.1
  • 56
    • 84919933641 scopus 로고    scopus 로고
    • Combinatorialization of fungal polyketide synthase–peptide synthetase hybrid proteins
    • Kakule, T.B., et al. Combinatorialization of fungal polyketide synthase–peptide synthetase hybrid proteins. J. Am. Chem. Soc. 136 (2014), 17882–17890.
    • (2014) J. Am. Chem. Soc. , vol.136 , pp. 17882-17890
    • Kakule, T.B.1
  • 57
    • 84984853918 scopus 로고    scopus 로고
    • Linker flexibility facilitates module exchange in fungal hybrid PKS-NRPS engineering
    • Nielsen, M.N., et al. Linker flexibility facilitates module exchange in fungal hybrid PKS-NRPS engineering. PLoS One, 11, 2016, e0161199.
    • (2016) PLoS One , vol.11
    • Nielsen, M.N.1
  • 58
    • 84880809096 scopus 로고    scopus 로고
    • Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis
    • Xu, Y., et al. Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis. J. Am. Chem. Soc. 135 (2013), 10783–10791.
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 10783-10791
    • Xu, Y.1
  • 59
    • 84896929356 scopus 로고    scopus 로고
    • Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases
    • Liu, T., et al. Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases. Org. Lett. 16 (2014), 1676–1679.
    • (2014) Org. Lett. , vol.16 , pp. 1676-1679
    • Liu, T.1
  • 60
    • 85006401259 scopus 로고    scopus 로고
    • Engineering fungal nonribosomal peptide synthetase-like enzymes by heterologous expression and domain swapping
    • Van Dijk, J.W.A., et al. Engineering fungal nonribosomal peptide synthetase-like enzymes by heterologous expression and domain swapping. Org. Lett. 18 (2016), 6236–6239.
    • (2016) Org. Lett. , vol.18 , pp. 6236-6239
    • Van Dijk, J.W.A.1
  • 61
    • 85019636013 scopus 로고    scopus 로고
    • Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
    • 15349
    • Yu, D., et al. Decoding and reprogramming fungal iterative nonribosomal peptide synthetases. Nat. Commun., 8, 2017 15349.
    • (2017) Nat. Commun. , vol.8
    • Yu, D.1
  • 62
    • 84955645373 scopus 로고    scopus 로고
    • An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping
    • Qin, B., et al. An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping. Angew. Chem. Int. Ed. Engl. 55 (2016), 1658–1661.
    • (2016) Angew. Chem. Int. Ed. Engl. , vol.55 , pp. 1658-1661
    • Qin, B.1
  • 63
    • 84901036306 scopus 로고    scopus 로고
    • Systematic domain swaps of iterative, nonreducing polyketide synthases provide a mechanistic understanding and rationale for catalytic reprogramming
    • Newman, A.G., et al. Systematic domain swaps of iterative, nonreducing polyketide synthases provide a mechanistic understanding and rationale for catalytic reprogramming. J. Am. Chem. Soc. 136 (2014), 7348–7362.
    • (2014) J. Am. Chem. Soc. , vol.136 , pp. 7348-7362
    • Newman, A.G.1
  • 64
    • 85040970481 scopus 로고    scopus 로고
    • Biocatalytic site- and enantioselective oxidative dearomatization of phenols
    • Baker Dockrey, S.A., et al. Biocatalytic site- and enantioselective oxidative dearomatization of phenols. Nat. Chem. 10 (2017), 119–125.
    • (2017) Nat. Chem. , vol.10 , pp. 119-125
    • Baker Dockrey, S.A.1
  • 65
    • 85028969744 scopus 로고    scopus 로고
    • Stereoselective total synthesis of bisorbicillinoid natural products by enzymatic oxidative dearomatization/dimerization
    • Sib, A., Gulder, T.A.M., Stereoselective total synthesis of bisorbicillinoid natural products by enzymatic oxidative dearomatization/dimerization. Angew. Chem. Int. Ed. Engl. 56 (2017), 12888–12891.
    • (2017) Angew. Chem. Int. Ed. Engl. , vol.56 , pp. 12888-12891
    • Sib, A.1    Gulder, T.A.M.2
  • 66
    • 85028870613 scopus 로고    scopus 로고
    • A reductive aminase from Aspergillus oryzae
    • Aleku, G.A., et al. A reductive aminase from Aspergillus oryzae. Nat. Chem. 9 (2017), 961–969.
    • (2017) Nat. Chem. , vol.9 , pp. 961-969
    • Aleku, G.A.1
  • 67
    • 85028340067 scopus 로고    scopus 로고
    • Enzymatic synthesis of psilocybin
    • Fricke, J., et al. Enzymatic synthesis of psilocybin. Angew. Chem. Int. Ed. Engl. 56 (2017), 12352–12355.
    • (2017) Angew. Chem. Int. Ed. Engl. , vol.56 , pp. 12352-12355
    • Fricke, J.1
  • 68
    • 84961830171 scopus 로고    scopus 로고
    • Biosynthetic pathway of the reduced polyketide product citreoviridin in Aspergillus terreus var. aureus revealed by heterologous expression in Aspergillus nidulans
    • Lin, T.S., et al. Biosynthetic pathway of the reduced polyketide product citreoviridin in Aspergillus terreus var. aureus revealed by heterologous expression in Aspergillus nidulans. Org. Lett. 18 (2016), 1366–1369.
    • (2016) Org. Lett. , vol.18 , pp. 1366-1369
    • Lin, T.S.1
  • 69
    • 84882966238 scopus 로고    scopus 로고
    • Heterologous reconstitution of the intact geodin gene cluster in Aspergillus nidulans through a simple and versatile PCR based approach
    • Nielsen, M.T., et al. Heterologous reconstitution of the intact geodin gene cluster in Aspergillus nidulans through a simple and versatile PCR based approach. PLoS One, 8, 2013, e72871.
    • (2013) PLoS One , vol.8
    • Nielsen, M.T.1
  • 70
    • 85048502753 scopus 로고    scopus 로고
    • Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi
    • Hoefgen, S., et al. Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab. Eng. 48 (2018), 44–51.
    • (2018) Metab. Eng. , vol.48 , pp. 44-51
    • Hoefgen, S.1
  • 71
    • 85031675929 scopus 로고    scopus 로고
    • A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore
    • e01478-17
    • Brandenburger, E., et al. A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore. Appl. Environ. Microbiol., 83, 2017 e01478-17.
    • (2017) Appl. Environ. Microbiol. , vol.83
    • Brandenburger, E.1
  • 72
    • 84908635350 scopus 로고    scopus 로고
    • Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid
    • Matsuda, Y., et al. Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid. J. Am. Chem. Soc. 136 (2014), 15326–15336.
    • (2014) J. Am. Chem. Soc. , vol.136 , pp. 15326-15336
    • Matsuda, Y.1
  • 73
    • 84971330701 scopus 로고    scopus 로고
    • Heterologous production of fungal maleidrides reveals the cryptic cyclization involved in their biosynthesis
    • Williams, K., et al. Heterologous production of fungal maleidrides reveals the cryptic cyclization involved in their biosynthesis. Angew. Chem. Int. Ed. Engl. 55 (2016), 6784–6788.
    • (2016) Angew. Chem. Int. Ed. Engl. , vol.55 , pp. 6784-6788
    • Williams, K.1
  • 74
    • 85034762224 scopus 로고    scopus 로고
    • Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis
    • Lv, J.M., et al. Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis. Nat. Commun., 8, 2017, 1644.
    • (2017) Nat. Commun. , vol.8 , pp. 1644
    • Lv, J.M.1
  • 75
    • 84929465994 scopus 로고    scopus 로고
    • Reconstitution of biosynthetic machinery for the synthesis of the highly elaborated indole diterpene penitrem
    • Liu, C., et al. Reconstitution of biosynthetic machinery for the synthesis of the highly elaborated indole diterpene penitrem. Angew. Chem. Int. Ed. Engl. 54 (2015), 5748–5752.
    • (2015) Angew. Chem. Int. Ed. Engl. , vol.54 , pp. 5748-5752
    • Liu, C.1
  • 76
    • 85047250314 scopus 로고    scopus 로고
    • Three previously unrecognized classes of biosynthetic enzymes revealed during the production of xenovulene A
    • Schor, R., et al. Three previously unrecognized classes of biosynthetic enzymes revealed during the production of xenovulene A. Nat. Commun., 9, 2018, 1963.
    • (2018) Nat. Commun. , vol.9 , pp. 1963
    • Schor, R.1
  • 77
    • 84929598168 scopus 로고    scopus 로고
    • Biosynthesis of the tetramic acids Sch210971 and Sch210972
    • Kakule, T.B., et al. Biosynthesis of the tetramic acids Sch210971 and Sch210972. Org. Lett. 17 (2015), 2295–2297.
    • (2015) Org. Lett. , vol.17 , pp. 2295-2297
    • Kakule, T.B.1
  • 78
    • 85040647449 scopus 로고    scopus 로고
    • Heterologous biosynthesis of nodulisporic acid F
    • Van de Bittner, K.C., et al. Heterologous biosynthesis of nodulisporic acid F. J. Am. Chem. Soc. 140 (2018), 582–585.
    • (2018) J. Am. Chem. Soc. , vol.140 , pp. 582-585
    • Van de Bittner, K.C.1
  • 79
    • 84876784070 scopus 로고    scopus 로고
    • High-level semi-synthetic production of the potent antimalarial artemisinin
    • Paddon, C.J., et al. High-level semi-synthetic production of the potent antimalarial artemisinin. Nature 496 (2013), 528–532.
    • (2013) Nature , vol.496 , pp. 528-532
    • Paddon, C.J.1
  • 80
    • 85039041158 scopus 로고    scopus 로고
    • Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeast
    • 15202
    • Awan, R.B., et al. Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeast. Nat. Commun., 8, 2017 15202.
    • (2017) Nat. Commun. , vol.8
    • Awan, R.B.1
  • 81
    • 84926646130 scopus 로고    scopus 로고
    • Distributing a metabolic pathway among a microbial consortium enhances production of natural products
    • Zhou, K., et al. Distributing a metabolic pathway among a microbial consortium enhances production of natural products. Nat. Biotechnol. 33 (2015), 377–383.
    • (2015) Nat. Biotechnol. , vol.33 , pp. 377-383
    • Zhou, K.1
  • 82
    • 84941346066 scopus 로고    scopus 로고
    • Complete biosynthesis of opioids in yeast
    • Galanie, S., et al. Complete biosynthesis of opioids in yeast. Science 349 (2015), 1095–1100.
    • (2015) Science , vol.349 , pp. 1095-1100
    • Galanie, S.1
  • 83
    • 84963984257 scopus 로고    scopus 로고
    • P450-mediated coupling of indole fragments to forge communesin and unnatural isomers
    • Lin, H.C., et al. P450-mediated coupling of indole fragments to forge communesin and unnatural isomers. J. Am. Chem. Soc. 138 (2016), 4002–4005.
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 4002-4005
    • Lin, H.C.1
  • 84
    • 85028655307 scopus 로고    scopus 로고
    • Function and structure of MalA/MalA′ iterative halogenases for late-stage C–H functionalization of indole alkaloids
    • Fraley, A.E., et al. Function and structure of MalA/MalA′ iterative halogenases for late-stage C–H functionalization of indole alkaloids. J. Am. Chem. Soc. 139 (2017), 12060–12068.
    • (2017) J. Am. Chem. Soc. , vol.139 , pp. 12060-12068
    • Fraley, A.E.1
  • 85
    • 84923199658 scopus 로고    scopus 로고
    • Functional characterization of MpaG′ the O-methyltransferase involved in the biosynthesis of mycophenolic acid
    • Zhang, W., et al. Functional characterization of MpaG′ the O-methyltransferase involved in the biosynthesis of mycophenolic acid. Chembiochem 16 (2015), 565–569.
    • (2015) Chembiochem , vol.16 , pp. 565-569
    • Zhang, W.1
  • 86
    • 84986584134 scopus 로고    scopus 로고
    • OxaD: a versatile indolic nitrone synthase from the marine-derived fungus Penicillium oxalicum F30
    • Newmister, S.A., et al. OxaD: a versatile indolic nitrone synthase from the marine-derived fungus Penicillium oxalicum F30. J. Am. Chem. Soc. 138 (2016), 11176–11184.
    • (2016) J. Am. Chem. Soc. , vol.138 , pp. 11176-11184
    • Newmister, S.A.1
  • 87
    • 84935921571 scopus 로고    scopus 로고
    • Kinetic characterization of the FAD dependent monooxygenase TropB and investigation of its biotransformation potential
    • Abood, A., et al. Kinetic characterization of the FAD dependent monooxygenase TropB and investigation of its biotransformation potential. RSC Adv. 5 (2015), 49987–49995.
    • (2015) RSC Adv. , vol.5 , pp. 49987-49995
    • Abood, A.1


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