Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast

Journal of the American Chemical Society

Volumn 137, Issue 43, 2015, Pages 13724-13727

  Tang, Man Cheng ^a   Lin, Hsiao Ching ^a   Li, Dehai ^a,d   Zou, Yi ^a   Li, Jian ^c   Xu, Wei ^a   Cacho, Ralph A ^a   Hillenmeyer, Maureen E ^c   Garg, Neil K ^b   Tang, Yi ^a,b  

^a Engineering IV   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOSYNTHESIS; ENZYMES; FUNGI; POLYCYCLIC AROMATIC HYDROCARBONS; YEAST;

BIOSYNTHETIC PATHWAY; CHEMICAL DIVERSITY; CYCLASES; DITERPENES; LARGE PARTS; LINEAR PRECURSORS; REASSEMBLY; STRUCTURAL DIVERSITY;

CYCLIZATION;

DITERPENE; INDOLE DERIVATIVE; INDOLE DITERPENE DERIVATIVE; UNCLASSIFIED DRUG; LYASE;

ARTICLE; BIOSYNTHESIS; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; CYCLIZATION; NONHUMAN; PHYLOGENY; SACCHAROMYCES CEREVISIAE; CHEMISTRY; CONFORMATION; ENZYMOLOGY; GENETIC ENGINEERING; GENETICS; METABOLISM;

BIOSYNTHETIC PATHWAYS; CYCLIZATION; DITERPENES; GENETIC ENGINEERING; INDOLES; MOLECULAR CONFORMATION; PHOSPHORUS-OXYGEN LYASES; SACCHAROMYCES CEREVISIAE;

EID: 84953432269     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b06108     Document Type: Article

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