Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History

Cell

Volumn 175, Issue 2, 2018, Pages 347-359.e14

  Liu, Siyang ^a,b   Huang, Shujia ^a,c   Chen, Fang ^a,b,u   Zhao, Lijian ^a   Yuan, Yuying ^a   Francis, Stephen Starko ^d,e   Fang, Lin ^a   Li, Zilong ^f   Lin, Long ^f   Liu, Rong ^a   Zhang, Yong ^a   Xu, Huixin ^a   Li, Shengkang ^a   Zhou, Yuwen ^a,f   Davies, Robert W ^g   Liu, Qiang ^a   Walters, Robin G ^h   Lin, Kuang ^h   Ju, Jia ^a   Korneliussen, Thorfinn ⁱ   Yang, Melinda A ^j   Fu, Qiaomei ^f,j,k   Wang, Jun ^a   Zhou, Lijun ^a   Krogh, Anders ^b   Zhang, Hongyun ^a   Wang, Wei ^a   Chen, Zhengming ^h   Cai, Zhiming ^l,m,n   Yin, Ye ^a   Yang, Huanming ^a,o   Mao, Mao ^a   Shendure, Jay ^p,q,r   Wang, Jian ^a,o   Albrechtsen, Anders ^b   Jin, Xin ^a,c   Nielsen, Rasmus ^s,t   Xu, Xun ^a   more..

^a BGI SHENZHEN   (China)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^d UNIVERSITY OF NEVADA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^g HOSPITAL FOR SICK CHILDREN   (Canada)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^j INSTITUTE OF VERTEBRATE PALEONTOLOGY AND PALEOANTHROPOLOGY   (China)

^k INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^l THE FIRST AFFILIATED HOSPITAL OF SHENZHEN UNIVERSITY   (China)

^m Guangdong Key Laboratory of Systems Biology and Synthetic Biology for Urogenital Tumors   (China)

ⁿ SHENZHEN UNIVERSITY   (China)

^o James D Watson Institute of Genome Science   (China)

^p UNIVERSITY OF WASHINGTON   (United States)

^q HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^r BROTMAN BATY INSTITUTE FOR PRECISION MEDICINE   (United States)

^s UNIVERSITY OF CALIFORNIA   (United States)

^t UNIVERSITY OF COPENHAGEN   (Denmark)

^u BGI Tech BGI Shenzhen   (China)

more..

Author keywords

genome wide association study; low pass sequencing; non invasive prenatal testing; plasma virome; population genetics

Indexed keywords

PIWI INTERACTING RNA; DNA;

ADULT; ARTICLE; BODY HEIGHT; BODY MASS; CHINESE; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE PHENOTYPE CORRELATION; GEOGRAPHIC DISTRIBUTION; HEPATITIS B; HUMAN; HUMAN HERPESVIRUS 6; MAJOR CLINICAL STUDY; MATERNAL AGE; MATERNAL PLASMA; MOLECULAR GENETICS; PHENOTYPE; POPULATION GENETICS; POPULATION RESEARCH; POPULATION STRUCTURE; PRENATAL DIAGNOSIS; PREVALENCE; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TWIN PREGNANCY; VIRUS INFECTION; WHOLE GENOME SEQUENCING; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DNA SEQUENCE; ETHNIC GROUP; GENETIC SCREENING; GENETIC VARIATION; GENETICS; GENOMICS; MIGRATION; PREGNANCY; PROCEDURES;

ADULT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DNA; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENETIC TESTING; GENETIC VARIATION; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMAN MIGRATION; HUMANS; PREGNANCY; PRENATAL DIAGNOSIS; SEQUENCE ANALYSIS, DNA;

EID: 85054028714     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2018.08.016     Document Type: Article

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