Non-invasive prenatal testing for trisomies 21, 18 and 13: Clinical experience from 146 958 pregnancies

Ultrasound in Obstetrics and Gynecology

Volumn 45, Issue 5, 2015, Pages 530-538

  Zhang, H ^a,b,d   Gao, Y ^a,b   Jiang, F ^a,b   Fu, M ^a,b   Yuan, Y ^a,b   Guo, Y ^a,b   Zhu, Z ^a,b   Lin, M ^a,b   Liu, Q ^a,b   Tian, Z ^a,c   Chen, F ^a,e   Lau, T K ^f   Zhao, L ^a,b   Yi, X ^a   Yin, Y ^a   Wang, W ^a,b  

^a BGI SHENZHEN   (China)

^b BGI Clinical Laboratories (Shenzhen) Co Ltd   (China)

^c BGI Tianjin   (China)

^d BGI Shenzhen   (China)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f 4 F Central Building   (Hong Kong)

Author keywords

cell free DNA; clinical performance; CNV; false negative; false positive; low risk population; mosaicism; NIPT; trisomy

Indexed keywords

DNA;

ADULT; CELL FREE SYSTEM; CHINA; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME DISORDERS; CLINICAL TRIAL; COMPARATIVE STUDY; DNA METHYLATION; DOWN SYNDROME; EMBRYOLOGY; EPIDEMIOLOGY; FEMALE; FOLLOW UP; GENETIC SCREENING; GENETICS; HUMAN; MATERNAL SERUM SCREENING TEST; MULTICENTER STUDY; NEWBORN; PREGNANCY; PREGNANCY OUTCOME; PRENATAL DIAGNOSIS; PROCEDURES; REPRODUCIBILITY; TRISOMY;

ADULT; CELL-FREE SYSTEM; CHINA; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 18; DNA; DNA METHYLATION; DOWN SYNDROME; FEMALE; FOLLOW-UP STUDIES; GENETIC TESTING; HUMANS; INFANT, NEWBORN; MATERNAL SERUM SCREENING TESTS; PREGNANCY; PREGNANCY OUTCOME; PRENATAL DIAGNOSIS; REPRODUCIBILITY OF RESULTS; TRISOMY;

EID: 84928601078     PISSN: 09607692     EISSN: 14690705     Source Type: Journal    
DOI: 10.1002/uog.14792     Document Type: Article

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