Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

American Journal of Human Genetics

Volumn 98, Issue 3, 2016, Pages 456-472

  Galinsky, Kevin J ^a,b   Bhatia, Gaurav ^a,b   Loh, Po Ru ^a,b   Georgiev, Stoyan ^c   Mukherjee, Sayan ^d   Patterson, Nick J ^b   Price, Alkes L ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c GOOGLE INC   (United States)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE 1B; HLA ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; INTERFERON REGULATORY FACTOR 4; SOMATOMEDIN BINDING PROTEIN 3; TOLL LIKE RECEPTOR 1; UNCLASSIFIED DRUG; ADH1B PROTEIN, HUMAN; IGFBP3 PROTEIN, HUMAN;

ALCOHOLISM; ALLELE; ARTICLE; COHORT ANALYSIS; CONVERGENT EVOLUTION; EAST ASIAN; EUROPE; EUROPEAN AMERICAN; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC DRIFT; HUMAN; MAJOR CLINICAL STUDY; NATURAL SELECTION; POPULATION STRUCTURE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MODEL; BIOLOGY; CAUCASIAN; FAR EAST; GENETIC DATABASE; GENETIC SELECTION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MOLECULAR EVOLUTION; PHYLOGENY; POPULATION GENETICS;

ALCOHOL DEHYDROGENASE; ASIAN CONTINENTAL ANCESTRY GROUP; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; FAR EAST; GENETIC LOCI; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; MODELS, GENETIC; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; SELECTION, GENETIC;

EID: 84960097618     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.12.022     Document Type: Article

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