Selection in Europeans on fatty acid desaturases associated with dietary changes

Molecular Biology and Evolution

Volumn 34, Issue 6, 2017, Pages 1307-1318

  Buckley, Matthew T ^a   Racimo, Fernando ^a   Allentoft, Morten E ^b   Jensen, Majken K ^c   Jonsson, Anna ^d   Huang, Hongyan ^c   Hormozdiari, Farhad ^e   Sikora, Martin ^b   Marnetto, Davide ^f   Eskin, Eleazar ^e,g   Jørgensen, Marit E ^h,i   Grarup, Niels ^d   Pedersen, Oluf ^d   Hansen, Torben ^d   Kraft, Peter ^c   Willerslev, Eske ^b   Nielsen, Rasmus ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d Capital Region   (Denmark)

^e Engineering IV   (United States)

^f UNIVERSITY OF TURIN   (Italy)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

ⁱ STENO DIABETES CENTER   (Denmark)

Author keywords

Evolution; FADS; Genetics; Human; Selection

Indexed keywords

ACYL COENZYME A DESATURASE; ARACHIDONIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; POLYUNSATURATED FATTY ACID; ANCIENT DNA; FAT INTAKE; FATTY ACID; UNSATURATED FATTY ACID;

ALLELE; ARTICLE; BRONZE AGE; DIETARY INTAKE; EUROPEAN; FATTY ACID SYNTHESIS; FOLLOW UP; FOOD COMPOSITION; GENE EXPRESSION; GENE FREQUENCY; GENE TARGETING; GENOTYPE ENVIRONMENT INTERACTION; GREENLAND; HAPLOTYPE; HEALTH PRACTITIONER; HUMAN; METABOLOMICS; NURSE; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH ASIA; CAUCASIAN; DIET; DNA SEQUENCE; FAT INTAKE; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MULTIGENE FAMILY;

ALLELES; DIET; DIETARY FATS; DNA, ANCIENT; EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; FATTY ACID DESATURASES; FATTY ACIDS; FATTY ACIDS, UNSATURATED; GENE FREQUENCY; GENE-ENVIRONMENT INTERACTION; HUMANS; LINOLEIC ACID; LIPIDS; MULTIGENE FAMILY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 85027406512     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msx103     Document Type: Article

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