Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Nature Genetics

Volumn 44, Issue 6, 2012, Pages 631-635

  Pasaniuc, Bogdan ^a,b   Rohland, Nadin ^b,c   McLaren, Paul J ^b,d   Garimella, Kiran ^b   Zaitlen, Noah ^a,b   Li, Heng ^b   Gupta, Namrata ^b   Neale, Benjamin M ^b,e   Daly, Mark J ^b,e   Sklar, Pamela ^f   Sullivan, Patrick F ^g   Bergen, Sarah ^b   Moran, Jennifer L ^b   Hultman, Christina M ^h   Lichtenstein, Paul ^h   Magnusson, Patrik ^h   Purcell, Shaun M ^b,e   Haas, David W ⁱ   Liang, Liming ^a,b   Sunyaev, Shamil ^b,d   Patterson, Nick ^b   De Bakker, Paul I W ^b,d,j   Reich, David ^b,c   Price, Alkes L ^a,b   more..

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^h KAROLINSKA INSTITUTE   (Sweden)

ⁱ VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; PRIORITY JOURNAL; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS;

EXOME; GENOME-WIDE ASSOCIATION STUDY; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 84861598099     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2283     Document Type: Article

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