Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

Cell Host and Microbe

Volumn 24, Issue 2, 2018, Pages 234-248.e5

  Zhang, Junjie ^a,i   Zhao, Jun ^a,i   Xu, Simin ^a,i   Li, Junhua ^a,i   He, Shanping ^a,b   Zeng, Yi ^c   Xie, Linshen ^d   Xie, Na ^a,e   Liu, Ting ^a   Lee, Katie ^a   Seo, Gil Ju ^a   Chen, Lin ^f   Stabell, Alex C ^g   Xia, Zanxian ^h   Sawyer, Sara L ^g   Jung, Jae ^a   Huang, Canhua ^e   Feng, Pinghui ^a,i  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b HUNAN NORMAL UNIVERSITY   (China)

^c YOUJIANG MEDICAL UNIVERSITY FOR NATIONALITIES   (China)

^d SICHUAN UNIVERSITY   (China)

^e SICHUAN UNIVERSITY   (China)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g UNIVERSITY OF COLORADO   (United States)

^h CENTRAL SOUTH UNIVERSITY   (China)

ⁱ UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

cGAS; cross species transmission; herpesvirus; HSV 1; immune evasion; protein deamination

Indexed keywords

BETA INTERFERON; CYCLIC GMP AMP SYNTHASE; HERPES SIMPLEX VIRUS 1 UL37 TEGUMENT PROTEIN; SYNTHETASE; UNCLASSIFIED DRUG; VIRAL PROTEIN; CYCLIC GUANOSINE MONOPHOSPHATE-ADENOSINE MONOPHOSPHATE; CYCLIC NUCLEOTIDE; MB21D1 PROTEIN, HUMAN; MB21D1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE; UL37 PROTEIN, HUMAN HERPESVIRUS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEAMINATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FIBROBLAST; HOST RESISTANCE; HUMAN ALPHAHERPESVIRUS 1; IMMUNE EVASION; IN VITRO STUDY; INNATE IMMUNITY; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; GENETICS; HOST PATHOGEN INTERACTION; KNOCKOUT MOUSE; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PRIMATE; SPECIES DIFFERENCE;

ANIMALS; FEMALE; HERPESVIRUS 1, HUMAN; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEOTIDES, CYCLIC; NUCLEOTIDYLTRANSFERASES; PRIMATES; SPECIES SPECIFICITY; VIRAL STRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 85050873728     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2018.07.004     Document Type: Article

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