Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation

Cell Host and Microbe

Volumn 22, Issue 5, 2017, Pages 627-638.e7

  Meyerson, Nicholas R ^a   Zhou, Ligang ^b   Guo, Yusong R ^c   Zhao, Chen ^b   Tao, Yizhi J ^c   Krug, Robert M ^b   Sawyer, Sara L ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c RICE UNIVERSITY   (United States)

Author keywords

Influenza virus; nuclear TRIM25; viral ribonucleoproteins; viral RNA synthesis

Indexed keywords

CAPPED RNA; NONSTRUCTURAL PROTEIN 1; RNA POLYMERASE; TRIM25 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; VIRUS RNA; ANTIVIRUS AGENT; CARRIER PROTEIN; DDX58 PROTEIN, HUMAN; INS1 PROTEIN, INFLUENZA VIRUS; INTERFERON; MESSENGER RNA; PROTEIN BINDING; RETINOIC ACID INDUCIBLE PROTEIN I; RIBONUCLEOPROTEIN; SUMO 1 PROTEIN; TRANSCRIPTION FACTOR; TRIM25 PROTEIN, HUMAN; TRIM5 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE; VIRAL PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLUENZA A VIRUS; INFLUENZA VIRUS; MESSENGER RNA SYNTHESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA STRUCTURE; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; A-549 CELL LINE; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; INFLUENZA; INFLUENZA A VIRUS (H3N2); METABOLISM; MOLECULAR MODEL; PATHOGENICITY; UBIQUITINATION;

A549 CELLS; ANTIVIRAL AGENTS; CARRIER PROTEINS; CELL LINE; DEAD BOX PROTEIN 58; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA, HUMAN; INTERFERONS; MODELS, MOLECULAR; PROTEIN BINDING; RIBONUCLEOPROTEINS; RNA, MESSENGER; RNA, VIRAL; SUMO-1 PROTEIN; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 85032382654     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.10.003     Document Type: Article

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