Species difference in ANP32A underlies influenza A virus polymerase host restriction

Nature

Volumn 529, Issue 7584, 2016, Pages 101-104

  Long, Jason S ^a   Giotis, Efstathios S ^a   Moncorgé, Olivier ^b   Frise, Rebecca ^a   Mistry, Bhakti ^a   James, Joe ^a,c   Morisson, Mireille ^d   Iqbal, Munir ^c   Vignal, Alain ^d   Skinner, Michael A ^a   Barclay, Wendy S ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b CNRS   (France)

^c INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^d UMR1388 GenPhySE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANP32A PROTEIN; PROTEIN; UNCLASSIFIED DRUG; ANP32A PROTEIN, HUMAN; AVIAN PROTEIN; PB2 PROTEIN, INFLUENZAVIRUS A; RNA DIRECTED RNA POLYMERASE; SIGNAL PEPTIDE; VIRAL PROTEIN;

AMINO ACID; AVIAN INFLUENZA; HOST-PATHOGEN INTERACTION; INFECTIVITY; PROTEIN; RNA;

ARTICLE; CHICKEN; CONTROLLED STUDY; EMBRYO; GENE DELETION; GENE INSERTION; GENE SEQUENCE; GENETIC SELECTION; HEK293 CELL LINE; HOST; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA A VIRUS (H5N1); INFLUENZA A VIRUS (H7N9); NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CRICETULUS; DEFICIENCY; DOG; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; HAMSTER; HOST RANGE; INFLUENZA A VIRUS; METABOLISM; MOLECULAR EVOLUTION; PHYSIOLOGY; VIROLOGY;

AVES; INFLUENZA A VIRUS; MAMMALIA; ORTHOMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; AVIAN PROTEINS; CELL LINE; CHICKENS; CRICETINAE; CRICETULUS; DOGS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, VIRAL; GENE KNOCKDOWN TECHNIQUES; HOST SPECIFICITY; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA A VIRUS, H7N9 SUBTYPE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; RNA REPLICASE; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84953931983     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16474     Document Type: Article

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