Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

PLoS ONE

Volumn 13, Issue 6, 2018, Pages

  Feitosa, Mary F ^a   Kraja, Aldi T ^a   Chasman, Daniel I ^b,c   Sung, Yun J ^a   Winkler, Thomas W ^d   Ntalla, Ioanna ^e   Guo, Xiuqing ^f   Franceschini, Nora ^g   Cheng, Ching Yu ^h,i,j   Sim, Xueling ^k   Vojinovic, Dina ^l   Marten, Jonathan ^m   Musani, Solomon K ⁿ   Li, Changwei ^o   Bentley, Amy R ^p   Brown, Michael R ^q   Schwander, Karen ^a   Richard, Melissa A ^r   Noordam, Raymond ^s   Aschard, Hugues ^t,u   Bartz, Traci M ^v   Bielak, Lawrence F ^w   Dorajoo, Rajkumar ^x   Fisher, Virginia ^y   Hartwig, Fernando P ^z,aa   Horimoto, Andrea R V R ^ab   Lohman, Kurt K ^ac   Manning, Alisa K ^c,ad   Rankinen, Tuomo ^ae   Smith, Albert V ^af,ag   Tajuddin, Salman M ^ah   Wojczynski, Mary K ^a   Alver, Maris ^ai   Boissel, Mathilde ^aj   Cai, Qiuyin ^ak   Campbell, Archie ^al   Chai, Jin Fang ^k   Chen, Xu ^am   Divers, Jasmin ^ac   Gao, Chuan ^ac   Goel, Anuj ^an,ao   Hagemeijer, Yanick ^ap   Harris, Sarah E ^al   He, Meian ^aq   Hsu, Fang Chi ^ac   Jackson, Anne U ^w   Kähönen, Mika ^ar,as   Kasturiratne, Anuradhani ^at   Komulainen, Pirjo ^au   Kühnel, Brigitte ^av   Laguzzi, Federica ^am   Luan, Jian'An ^aw   Matoba, Nana ^ax   Nolte, Ilja M ^ap   Padmanabhan, Sandosh ^ay   Riaz, Muhammad ^az,ba   Rueedi, Rico ^bb,bc   Robino, Antonietta ^bd   Said, M Abdullah ^ap   Scott, Robert A ^aw   Sofer, Tamar ^b,c   Stančáková, Alena ^au   Takeuchi, Fumihiko ^be   Tayo, Bamidele O ^bf   Van Der Most, Peter J ^ap   Varga, Tibor V ^bg   Vitart, Veronique ^m   Wang, Yajuan ^bh   Ware, Erin B ^w   Warren, Helen R ^e,bi   Weiss, Stefan ^bj,bk   Wen, Wanqing ^ak   Yanek, Lisa R ^bl   Zhang, Weihua ^bm,bn   Zhao, Jing Hua ^aw   Afaq, Saima ^bm   Amin, Najaf ^l   Amini, Marzyeh ^ap   Arking, Dan E ^bl   Aung, Tin ^h,i,j   Boerwinkle, Eric ^bo,bp   Borecki, Ingrid ^a   Broeckel, Ulrich ^bq   Brown, Morris ^e,bi   Brumat, Marco ^br   Burke, Gregory L ^ac   Canouil, Mickaël ^aj   Chakravarti, Aravinda ^bl   Charumathi, Sabanayagam ^h,i   Chen, Yii Der Ida ^f   Connell, John M ^bs   Correa, Adolfo ⁿ   De Las Fuentes, Lisa ^a,bt   De Mutsert, Renée ^s   De Silva, H Janaka ^at   Deng, Xuan ^y   Ding, Jingzhong ^bu   Duan, Qing ^bv   Eaton, Charles B ^bw   Ehret, Georg ^bx   Eppinga, Ruben N ^ap   Evangelou, Evangelos ^bm,by   Faul, Jessica D ^w   Felix, Stephan B ^bj,bk   Forouhi, Nita G ^aw   Forrester, Terrence ^bz   Franco, Oscar H ^l   Friedlander, Yechiel ^ca   Gandin, Ilaria ^br   Gao, He ^bm   Ghanbari, Mohsen ^l,cb   Gigante, Bruna ^am   Gu, C Charles ^a   Gu, Dongfeng ^cc   Hagenaars, Saskia P ^al   Hallmans, Göran ^cd   Harris, Tamara B ^ah   He, Jiang ^ce,cf   Heikkinen, Sami ^au   Heng, Chew Kiat ^j,k   Hirata, Makoto ^cg   Howard, Barbara V ^ch,ci   Ikram, M Arfan ^l   John, Ulrich ^bj,bk   Katsuya, Tomohiro ^cj   Khor, Chiea Chuen ^x,ck   Kilpeläinen, Tuomas O ^cl,cm   Koh, Woon Puay ^i,k   Krieger, José E ^ab   Kritchevsky, Stephen B ^ac   Kubo, Michiaki ^ax   Kuusisto, Johanna ^au   Lakka, Timo A ^au,cn   Langefeld, Carl D ^ac   Langenberg, Claudia ^aw   Launer, Lenore J ^ah   Lehne, Benjamin ^bm   Lewis, Cora E ^co   Li, Yize ^a   Lin, Shiow ^a   Liu, Jianjun ^k,x   Liu, Jingmin ^cp   Loh, Marie ^bm,cq   Louie, Tin ^cr   Mägi, Reedik ^ai   McKenzie, Colin A ^bz   Meitinger, Thomas ^av,cs   Metspalu, Andres ^ai   Milaneschi, Yuri ^ct   Milani, Lili ^ai   Mohlke, Karen L ^bv   Momozawa, Yukihide ^ax   Nalls, Mike A ^ah,cu   Nelson, Christopher P ^az,ba   Sotoodehnia, Nona ^v   Norris, Jill M ^cv   O'Connell, Jeff R ^cw   Palmer, Nicholette D ^ac   Perls, Thomas ^cx   Pedersen, Nancy L ^am   Peters, Annette ^av,bk   Peyser, Patricia A ^w   Poulter, Neil ^bm   Raffel, Leslie J ^cy   Raitakari, Olli T ^cz,da   Roll, Kathryn ^f   Rose, Lynda M ^b   Rosendaal, Frits R ^s   Rotter, Jerome I ^f   Schmidt, Carsten O ^bj   Schreiner, Pamela J ^db   Schupf, Nicole ^dc   Scott, William R ^bm,dd   Sever, Peter S ^dd   Shi, Yuan ^h   Sidney, Stephen ^de   Sims, Mario ⁿ   Sitlani, Colleen M ^v   Smith, Jennifer A ^w   Snieder, Harold ^ap   Starr, John M ^al   Strauch, Konstantin ^av,df   Stringham, Heather M ^w   Tan, Nicholas Y Q ^h   Tang, Hua ^dg   Taylor, Kent D ^f   Teo, Yik Ying ^k,x,ck   Tham, Yih Chung ^h   Turner, Stephen T ^dh   Uitterlinden, André G ^l   Vollenweider, Peter ^di   Waldenberger, Melanie ^av   Wang, Lihua ^a   Wang, Ya Xing ^dj   Wei, Wen Bin ^dj   Williams, Christine ^a   Yao, Jie ^f   Yu, Caizheng ^aq   Yuan, Jian Min ^dk,dl   Zhao, Wei ^w   Zonderman, Alan B ^ah   Becker, Diane M ^bl   Boehnke, Michael ^w   Bowden, Donald W ^ac   Chambers, John C ^bm,bn,dm,dn   Deary, Ian J ^al   Esko, Tõnu ^ai,do   Farrall, Martin ^an,ao   Franks, Paul W ^t,bg   Freedman, Barry I ^ac   Froguel, Philippe ^aj,bm   Gasparini, Paolo ^bd,br   Gieger, Christian ^av,dp   Jonas, Jost Bruno ^dj,dq   Kamatani, Yoichiro ^ax   Kato, Norihiro ^be   Kooner, Jaspal S ^bm,bn,dd,dn   Kutalik, Zoltán ^bc,dr   Laakso, Markku ^au   Laurie, Cathy C ^cr   Leander, Karin ^am   Lehtimäki, Terho ^as,ds   Magnusson, Patrik K E ^am   Oldehinkel, Albertine J ^ap   Penninx, Brenda W J H ^ct   Polasek, Ozren ^dt,du,dv   Porteous, David J ^al   Rauramaa, Rainer ^au   Samani, Nilesh J ^az,ba   Scott, James ^dd   Shu, Xiao Ou ^ak   Van Der Harst, Pim ^ap   Wagenknecht, Lynne E ^ac   Wareham, Nicholas J ^aw   Watkins, Hugh ^an,ao   Weir, David R ^w   Wickremasinghe, Ananda R ^at   Wu, Tangchun ^aq   Zheng, Wei ^ak   Bouchard, Claude ^ae   Christensen, Kaare ^dw   Evans, Michele K ^ah   Gudnason, Vilmundur ^af,ag   Horta, Bernardo L ^z   Kardia, Sharon L R ^w   Liu, Yongmei ^bu   Pereira, Alexandre C ^ab   Psaty, Bruce M ^v,dx   Ridker, Paul M ^b,c   Van Dam, Rob M ^k,dy   Gauderman, W James ^dz   Zhu, Xiaofeng ^bh   Mook Kanamori, Dennis O ^s   Fornage, Myriam ^q,r   Rotimi, Charles N ^p   Cupples, L Adrienne ^y,ea   Kelly, Tanika N ^ce   Fox, Ervin R ⁿ   Hayward, Caroline ^m   Van Duijn, Cornelia M ^l   Tai, E Shyong ^i,k,dy   Wong, Tien Yin ^h,i,j   Kooperberg, Charles ^cr   Palmas, Walter ^dc   Rice, Kenneth ^cr   Morrison, Alanna C ^q   Elliott, Paul ^bm   Caulfield, Mark J ^e,bi   Munroe, Patricia B ^e,bi   Rao, Dabeeru C ^a   Province, Michael A ^a   Levy, Daniel ^ea,eb   more..

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f HARBOR UCLA MEDICAL CENTER   (United States)

^g IL   (United States)

^h SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

ⁱ DUKE NUS MEDICAL SCHOOL   (Singapore)

^j NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^k NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^l ERASMUS MEDICAL CENTER   (Netherlands)

^m UNIVERSITY OF EDINBURGH   (United Kingdom)

ⁿ UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^o UNIVERSITY OF GEORGIA   (United States)

^p NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^q UNIVERSITY OF TEXAS   (United States)

^r UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^s LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^t HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^u INSTITUT PASTEUR   (France)

^v UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^w UNIVERSITY OF MICHIGAN   (United States)

^x GENOME INSTITUTE OF SINGAPORE   (Singapore)

^y BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^z FEDERAL UNIVERSITY OF PELOTAS   (Brazil)

^aa UNIVERSITY OF BRISTOL   (United Kingdom)

^ab UNIVERSITY OF SÃO PAULO   (Brazil)

^ac WAKE FOREST SCHOOL OF MEDICINE   (United States)

^ad MASSACHUSETTS GENERAL HOSPITAL   (United States)

^ae PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^af ICELANDIC HEART ASSOCIATION   (Iceland)

^ag UNIVERSITY OF ICELAND   (Iceland)

^ah NATIONAL INSTITUTE ON AGING   (United States)

^ai UNIVERSITY OF TARTU   (Estonia)

^aj UNIV LILLE   (France)

^ak VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^al UNIVERSITY OF EDINBURGH   (United Kingdom)

^am KAROLINSKA INSTITUTE   (Sweden)

^an UNIVERSITY OF OXFORD   (United Kingdom)

^ao UNIVERSITY OF OXFORD   (United Kingdom)

^ap UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^aq HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^ar TAMPERE UNIVERSITY HOSPITAL   (Finland)

^as TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^at UNIVERSITY OF KELANIYA   (Sri Lanka)

^au UNIVERSITY OF EASTERN FINLAND   (Finland)

^av INSTITUTE OF EPIDEMIOLOGY   (Germany)

^aw UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^ax RIKEN Center for Integrative Medical Sciences   (Japan)

^ay UNIVERSITY OF GLASGOW   (United Kingdom)

^az UNIVERSITY OF LEICESTER   (United Kingdom)

^ba GLENFIELD HOSPITAL   (United Kingdom)

^bb UNIVERSITY OF LAUSANNE   (Switzerland)

^bc Swiss Instititute of Bioinformatics   (Switzerland)

^bd INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^be NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^bf LOYOLA UNIVERSITY CHICAGO   (United States)

^bg LUND UNIVERSITY HOSPITAL   (Sweden)

^bh CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bi QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^bj UNIVERSITY MEDICINE GREIFSWALD   (Germany)

^bk DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^bl JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bm IMPERIAL COLLEGE LONDON   (United Kingdom)

^bn EALING HOSPITAL   (United Kingdom)

^bo UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^bp BAYLOR COLLEGE OF MEDICINE   (United States)

^bq MEDICAL COLLEGE OF WISCONSIN   (United States)

^br UNIVERSITY OF TRIESTE   (Italy)

^bs UNIVERSITY OF DUNDEE   (United Kingdom)

^bt WASHINGTON UNIVERSITY   (United States)

^bu WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^bv UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^bw BROWN UNIVERSITY   (United States)

^bx GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^by UNIVERSITY OF IOANNINA   (Greece)

^bz UNIVERSITY OF THE WEST INDIES   (Jamaica)

^ca HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^cb MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^cc FUWAI HOSPITAL   (China)

^cd UMEÅ UNIVERSITY   (Sweden)

^ce TULANE UNIVERSITY   (United States)

^cf TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^cg UNIVERSITY OF TOKYO   (Japan)

^ch MEDSTAR RESEARCH INSTITUTE   (United States)

^ci Delaware   (United States)

^cj OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^ck NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^cl Capital Region   (Denmark)

^cm MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^cn KUOPIO UNIVERSITY HOSPITAL   (Finland)

^co University of Alabama at Birmingham   (United States)

^cp Fred Hutchinson Cancer Research Center   (United States)

^cq AGENCY FOR SCIENCE   (Singapore)

^cr UNIVERSITY OF WASHINGTON   (United States)

^cs TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^ct VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^cu Data Tecnica International LLC   (United States)

^cv Global Health and Health Disparities   (United States)

^cw UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^cx BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^cy UNIVERSITY OF CALIFORNIA   (United States)

^cz TURKU UNIVERSITY HOSPITAL   (Finland)

^da UNIVERSITY OF TURKU   (Finland)

^db UNIVERSITY OF MINNESOTA   (United States)

^dc NewYork Presbyterian Hospital   (United States)

^dd NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^de DIVISION OF RESEARCH   (United States)

^df UNIVERSITY OF MUNICH   (Germany)

^dg STANFORD UNIVERSITY   (United States)

^dh MAYO CLINIC   (United States)

^di LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^dj CAPITAL MEDICAL UNIVERSITY   (China)

^dk UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^dl UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^dm NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^dn IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^do HARVARD UNIVERSITY   (United States)

^dp GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^dq UNIVERSITY OF HEIDELBERG   (Germany)

^dr UNIVERSITY OF LAUSANNE   (Switzerland)

^ds FIMLAB LABORATORIES   (Finland)

^dt UNIVERSITY OF SPLIT   (Croatia)

^du brankarestek petrovic pbsvihr   (Croatia)

^dv Gen Info Ltd   (Croatia)

^dw UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^dx KAISER PERMANENTE   (United States)

^dy Dept Medicine Endocrinol Diabet   (Singapore)

^dz UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^ea FRAMINGHAM HEART STUDY   (United States)

^eb NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ACE GENE; ADRB1 GENE; ADULT; AFRICAN; AGT GENE; ALCOHOL CONSUMPTION; ANCESTRY GROUP; ARTICLE; ASIAN; BLK GENE; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; BRAZILIAN; CARDIOMEGALY; CARDIOVASCULAR DISEASE; CATSPER2 GENE; CHROMOSOME 16Q; CHROMOSOME 8P; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DIASTOLIC BLOOD PRESSURE; EFEMP2 GENE; ERCC6 GENE; EUROPEAN; FAM167A GENE; FBN1 GENE; FTO GENE; GABRB1 GENE; GATA4 GENE; GENE; GENE ALCOHOL INTERACTION; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC TRAIT; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GRK5 GENE; HEALTH STATUS; HEART ARRHYTHMIA; HEART FAILURE; HEART HYPERTROPHY; HISPANIC; HUMAN; KCNJ11 GENE; MAJOR CLINICAL STUDY; MAPKAPK2 GENE; MEAN ARTERIAL PRESSURE; MTHFR GENE; MULTI ANCESTRY; NOS3 GENE; NPPA GENE; PATHOGENESIS; PINX1 GENE; PROTEIN PROTEIN INTERACTION; PULSE PRESSURE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION REGULATION; ADOLESCENT; AGED; DRINKING BEHAVIOR; FEMALE; GENETIC PREDISPOSITION; GENOTYPE ENVIRONMENT INTERACTION; HYPERTENSION; MALE; META ANALYSIS; MIDDLE AGED; PEDIGREE; STATISTICS AND NUMERICAL DATA; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BLOOD PRESSURE; COHORT STUDIES; CONTINENTAL POPULATION GROUPS; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 85049155160     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0198166     Document Type: Article

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