Ethanol Regulation of Serum Glucocorticoid Kinase 1 Expression in DBA2/J Mouse Prefrontal Cortex

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Costin, Blair N ^a   Dever, Seth M ^a   Miles, Michael F ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MYC PROTEIN; PHOSPHOTRANSFERASE; SERINE; SERUM GLUCOCORTICOID KINASE 1; UNCLASSIFIED DRUG;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE INDUCTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; REGULATORY MECHANISM; SGK1 GENE;

ANIMALS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; CORTICOSTERONE; DNA PRIMERS; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMEDIATE-EARLY PROTEINS; MICE; MICE, INBRED DBA; PHOSPHORYLATION; PITUITARY-ADRENAL SYSTEM; PREFRONTAL CORTEX; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER;

EID: 84882750177     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072979     Document Type: Article

References (53)

1. Schuckit MA, (1994) Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151: 184-189. PubMed: 8296886.
2. Metten P, Phillips TJ, Crabbe JC, Tarantino LM, McClearn GE, et al. (1998) High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption. Mamm Genome 9: 983-990. doi:10.1007/s003359900911. PubMed: 9880664.
3. Ellis FW, (1966) Effect of ethanol on plasma corticosterone levels. J Pharmacol Exp Ther 153: 121-127. PubMed: 4288396.
4. Marinelli M, Rougé-Pont F, Deroche V, Barrot M, De Jésus-Oliveira C, et al. (1997) Glucocorticoids and behavioral effects of psychostimulants. I: locomotor response to cocaine depends on basal levels of glucocorticoids. J Pharmacol Exp Ther 281: 1392-1400. PubMed: 9190875.
5. De Kloet ER, Vreugdenhil E, Oitzl MS, Joëls M, (1998) Brain corticosteroid receptor balance in health and disease. Endocr Rev 19: 269-301. doi:10.1210/er.19.3.269. PubMed: 9626555.
6. Webster NJ, Green S, Jin JR, Chambon P, (1988) The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell 54: 199-207. doi:10.1016/0092-8674(88)90552-1. PubMed: 3390864.
7. Costa A, Bono G, Martignoni E, Merlo P, Sances G, et al. (1996) An assessment of hypothalamo-pituitary-adrenal axis functioning in non-depressed, early abstinent alcoholics. Psychoneuroendocrinology 21: 263-275. doi:10.1016/0306-4530(96)00001-7. PubMed: 8817725.
8. Wand GS, Dobs AS, (1991) Alterations in the hypothalamic-pituitary-adrenal axis in actively drinking alcoholics. J Clin Endocrinol Metab 72: 1290-1295. doi:10.1210/jcem-72-6-1290. PubMed: 2026749.
9. Richardson HN, Lee SY, O'Dell LE, Koob GF, Rivier CL, (2008) Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state. Eur J Neurosci 28: 1641-1653. doi:10.1111/j.1460-9568.2008.06455.x. PubMed: 18979677.
10. Rasmussen DD, Boldt BM, Bryant CA, Mitton DR, Larsen SA, et al. (2000) Chronic daily ethanol and withdrawal: 1. Long-term changes in the hypothalamo-pituitary-adrenal axis. Alcohol Clin Exp Res 24: 1836-1849. doi:10.1111/j.1530-0277.2000.tb01988.x. PubMed: 11141043.
11. Roberts AJ, Lessov CN, Phillips TJ, (1995) Critical role for glucocorticoid receptors in stress- and ethanol-induced locomotor sensitization. J Pharmacol Exp Ther 275: 790-797. PubMed: 7473168.
12. Kerns RT, Ravindranathan A, Hassan S, Cage MP, York T, et al. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. J Neurosci 25: 2255-2266. doi:10.1523/JNEUROSCI.4372-04.2005. PubMed: 15745951.
13. Treadwell JA, Singh SM, (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. Neurochem Res 29: 357-369. doi:10.1023/B:NERE.0000013738.06437.a6. PubMed: 15002731.
14. Wolstenholme JT, Warner JA, Capparuccini MI, Archer KJ, Shelton KL, et al. (2011) Genomic analysis of individual differences in ethanol drinking: evidence for non-genetic factors in C57BL/6 mice. PLOS ONE 6: e21100. doi:10.1371/journal.pone.0021100. PubMed: 21698166.
15. Costin BN, Wolen AR, Fitting S, Shelton KL, Miles MF, (2012) Role of Adrenal Glucocorticoid Signaling in Prefrontal Cortex Gene Expression and Acute Behavioral Responses to Ethanol. Alcohol Clin Exp Res, 37: 57-66. PubMed: 22671426.
16. Wolen AR, Phillips CA, Langston MA, Putman AH, Vorster PJ, et al. (2012) Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications. PLOS ONE 7: e33575. doi:10.1371/journal.pone.0033575. PubMed: 22511924.
17. Piechota M, Korostynski M, Solecki W, Gieryk A, Slezak M, et al. (2010) The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum. Genome Biol 11: R48. doi:10.1186/gb-2010-11-5-r48. PubMed: 20459597.
18. Binder EB, (2009) The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 34 (Suppl 1):: S186-S195. doi:10.1016/j.psyneuen.2009.05.021. PubMed: 19560279.
19. Webster MK, Goya L, Ge Y, Maiyar AC, Firestone GL, (1993) Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol Cell Biol 13: 2031-2040. PubMed: 8455596.
20. Alvarez de la Rosa D, Zhang P, Naray-Fejes-Toth A, Fejes-Toth G, Canessa CM (1999) The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. J Biol Chem 274: 37834-37839.
21. Brunet A, Park J, Tran H, Hu LS, Hemmings BA, et al. (2001) Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 21: 952-965. doi:10.1128/MCB.21.3.952-965.2001. PubMed: 11154281.
22. Lee CT, Tyan SW, Ma YL, Tsai MC, Yang YC, et al. (2006) Serum- and glucocorticoid-inducible kinase (SGK) is a target of the MAPK/ERK signaling pathway that mediates memory formation in rats. Eur J Neurosci 23: 1311-1320. doi:10.1111/j.1460-9568.2006.04650.x. PubMed: 16553792.
23. Ma YL, Tsai MC, Hsu WL, Lee EH, (2006) SGK protein kinase facilitates the expression of long-term potentiation in hippocampal neurons. Learn Mem 13: 114-118. doi:10.1101/lm.179206. PubMed: 16585788.
24. Tsai KJ, Chen SK, Ma YL, Hsu WL, Lee EH, (2002) sgk, a primary glucocorticoid-induced gene, facilitates memory consolidation of spatial learning in rats. Proc Natl Acad Sci U S A 99: 3990-3995. doi:10.1073/pnas.062405399. PubMed: 11891330.
25. Arteaga MF, Coric T, Straub C, Canessa CM, (2008) A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons. Proc Natl Acad Sci U S A 105: 4459-4464. doi:10.1073/pnas.0800958105. PubMed: 18334630.
26. Arteaga MF, Alvarez de la Rosa D, Alvarez JA, Canessa CM, (2007) Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Mol Biol Cell 18: 2072-2080. doi:10.1091/mbc.E06-10-0968. PubMed: 17377066.
27. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034. PubMed: 12184808.
28. Schutz-Geschwender A, Zhang Y, Holt T, McDermitt D, Olive DM, (2004). uantitative Twocolor West Blot Detect Infrared Fluoresc: LICOR Biosciences.
29. Kobayashi T, Cohen P, (1999) Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem J 339(2):: 319-328. doi:10.1042/0264-6021:3390319. PubMed: 10191262.
30. Perrotti N, He RA, Phillips SA, Haft CR, Taylor SI, (2001) Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin. J Biol Chem 276: 9406-9412. doi:10.1074/jbc.M007052200. PubMed: 11096081.
31. Kobayashi T, Deak M, Morrice N, Cohen P, (1999) Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J 3441:: 189-197. doi:10.1042/0264-6021:3440189. PubMed: 10548550.
32. Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, et al. (1999) Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J 18: 3024-3033. doi:10.1093/emboj/18.11.3024. PubMed: 10357815.
33. Murray JT, Campbell DG, Morrice N, Auld GC, Shpiro N, et al. (2004) Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J 384: 477-488. doi:10.1042/BJ20041057. PubMed: 15461589.
34. Vendruscolo LF, Barbier E, Schlosburg JE, Misra KK, Whitfield TW Jr., et al. (2012) Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. J Neurosci 32: 7563-7571. doi:10.1523/JNEUROSCI.0069-12.2012. PubMed: 22649234.
35. Sorocco KH, Lovallo WR, Vincent AS, Collins FL, (2006) Blunted hypothalamic-pituitary-adrenocortical axis responsivity to stress in persons with a family history of alcoholism. Int J Psychophysiol 59: 210-217. doi:10.1016/j.ijpsycho.2005.10.009. PubMed: 16360227.
36. Dai X, Thavundayil J, Gianoulakis C, (2002) Response of the hypothalamic-pituitary-adrenal axis to stress in the absence and presence of ethanol in subjects at high and low risk of alcoholism. Neuropsychopharmacology 27: 442-452. doi:10.1016/S0893-133X(02)00308-1. PubMed: 12225701.
37. Mizoguchi K, Ishige A, Aburada M, Tabira T, (2003) Chronic stress attenuates glucocorticoid negative feedback: involvement of the prefrontal cortex and hippocampus. Neuroscience 119: 887-897. doi:10.1016/S0306-4522(03)00105-2. PubMed: 12809708.
38. Uhart M, Wand GS, (2009) Stress, alcohol and drug interaction: an update of human research. Addict Biol 14: 43-64. doi:10.1111/j.1369-1600.2008.00131.x. PubMed: 18855803.
39. Gamper N, Fillon S, Huber SM, Feng Y, Kobayashi T, et al. (2002) IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1. Pflugers Arch 443: 625-634. doi:10.1007/s00424-001-0741-5. PubMed: 11907830.
40. Wang J, Barbry P, Maiyar AC, Rozansky DJ, Bhargava A, et al. (2001) SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. Am J Physiol Renal Physiol 280: F303-F313. PubMed: 11208606.
41. Wesch D, Miranda P, Afonso-Oramas D, Althaus M, Castro-Hernández J, et al. (2010) The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling. Am J Physiol Cell Physiol 299: C779-C790. doi:10.1152/ajpcell.00184.2010. PubMed: 20631247.
42. Miranda P, Cadaveira-Mosquera A, González-Montelongo R, Villarroel A, González-Hernández T, et al. (2013) The Neuronal Serum- and Glucocorticoid-Regulated Kinase 1.1 Reduces Neuronal Excitability and Protects against Seizures through Upregulation of the M-Current. J Neurosci 33: 2684-2696. doi:10.1523/JNEUROSCI.3442-12.2013. PubMed: 23392695.
43. Lee S, Rivier C, (1997) An initial, three-day-long treatment with alcohol induces a long-lasting phenomenon of selective tolerance in the activity of the rat hypothalamic-pituitary-adrenal axis. J Neurosci 17: 8856-8866. PubMed: 9348353.
44. Spencer RL, McEwen BS, (1990) Adaptation of the hypothalamic-pituitary-adrenal axis to chronic ethanol stress. Neuroendocrinology 52: 481-489. doi:10.1159/000125632. PubMed: 2126355.
45. García-Martínez JM, Alessi DR, (2008) mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Biochem J 416: 375-385. doi:10.1042/BJ20081668. PubMed: 18925875.
46. Hong F, Larrea MD, Doughty C, Kwiatkowski DJ, Squillace R, et al. (2008) mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation. Mol Cell 30: 701-711. doi:10.1016/j.molcel.2008.04.027. PubMed: 18570873.
47. Sahin P, McCaig C, Jeevahan J, Murray JT, Hainsworth AH, (2013) The cell survival kinase SGK1 and its targets FOXO3a and NDRG1 in aged human brain. Neuropathol Appl Neurobiol. PubMed: 23363009.
48. Miyata S, Koyama Y, Takemoto K, Yoshikawa K, Ishikawa T, et al. (2011) Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum. PLOS ONE 6: e19859. doi:10.1371/journal.pone.0019859. PubMed: 21655274.
49. Okuda T, Kokame K, Miyata T, (2008) Differential expression patterns of NDRG family proteins in the central nervous system. J Histochem Cytochem 56: 175-182. PubMed: 17998568.
50. Wärntges S, Friedrich B, Henke G, Duranton C, Lang PA, et al. (2002) Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1. Pflugers Arch 443: 617-624. doi:10.1007/s00424-001-0737-1. PubMed: 11907829.
51. Lovallo WR, Dickensheets SL, Myers DA, Thomas TL, Nixon SJ, (2000) Blunted stress cortisol response in abstinent alcoholic and polysubstance-abusing men. Alcohol Clin Exp Res 24: 651-658. doi:10.1111/j.1530-0277.2000.tb02036.x. PubMed: 10832906.
52. O'Malley SS, Krishnan-Sarin S, Farren C, Sinha R, Kreek MJ, (2002) Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology (Berl) 160: 19-29. doi:10.1007/s002130100919.
53. Kiefer M, Ansorge U, Haynes JD, Hamker F, Mattler U, et al. (2011) Neuro-cognitive mechanisms of conscious and unconscious visual perception: From a plethora of phenomena to general principles. Adv Cogn Psychol 7: 55-67. doi:10.2478/v10053-008-0090-4. PubMed: 22253669.