Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population

Gene

Volumn 509, Issue 1, 2012, Pages 178-188

  Roy, Neelanjana ^a   Mukhopadhyay, Indranil ^b   Das, Kausik ^a   Pandit, Pratap ^a   Majumder, Partha P ^c   Santra, Amal ^a   Datta, Simanti ^a   Banerjee, Soma ^a   Chowdhury, Abhijit ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b INDIAN STATISTICAL INSTITUTE   (India)

^c NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS   (India)

Author keywords

Alcoholic liver disease; IL1 ; IL10; Polymorphism; TGF 1; TNF

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 1BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALCOHOL LIVER DISEASE; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 GENE; FATTY LIVER; FEMALE; GENE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; INDIAN; INTERLEUKIN 10 GENE; INTERLEUKIN 1BETA GENE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSFORMING GROWTH FACTOR BETA1 GENE; TUMOR NECROSIS FACTOR ALPHA GENE;

ADULT; BASE SEQUENCE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COHORT STUDIES; CTLA-4 ANTIGEN; DNA PRIMERS; ETHNIC GROUPS; FATTY LIVER, ALCOHOLIC; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; INDIA; INTERLEUKIN-10; INTERLEUKIN-1BETA; LIVER DISEASES, ALCOHOLIC; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866149999     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.07.077     Document Type: Article

References (57)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders-Text Revision (DSM-IV) 2000, Washington, DC, USA. 4th edn.
2. Ando T., et al. Interleukin 1B pro-inflammatory genotypes protect against gastro-esophageal reflux disease through induction of corpus atrophy. Gut 2006, 55:158-164.
3. Auguet T., et al. A study on the TNF-alpha system in Caucasian Spanish patients with alcoholic liver disease. Drug Alcohol Depend. 2008, 92:91-99.
4. Bassendine M.F., Day C.P. The inheritance of alcoholic liver disease. Baillière's Clin. Gastroenterol. 1998, 12:317-335.
5. Bathgate A.J., et al. Polymorphisms in tumor necrosis factor alpha, interleukin-10 and transforming growth factor b 1 genes and end-stage liver disease. Eur. J. Gastroenterol. Hepatol. 2000, 12:1329-1333.
6. Beauchamp R.D., et al. TGF-β stimulates hepatic jun-B and fos-B proto-oncogenes and decreases albumin mRNA. Ann. Surg. 1992, 216:300-307.
7. Becker U., et al. Lower risk of alcohol-induced cirrhosis in wine drinkers. Hepatology 2002, 35:868-875.
8. Bhaskar L.V., et al. Single nucleotide polymorphisms of the ALDH2 gene in six Indian populations. Ann. Hum. Biol. 2007, 34:607-619.
9. Caetano R., Babor T.F. Diagnosis of alcohol dependence in epidemiological surveys: an epidemic of youthful alcohol dependence or a case of measurement error?. Addiction 2006, 101(S1):111-114.
10. Castera L., et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 2005, 128:343-350.
11. Cubero F.J., et al. Alcohol and liver fibrosis. Semin. Liver Dis. 2009, 29:211-221.
12. Das K., et al. "Normal" liver stiffness measure (LSM) values are higher in both lean and obese individuals: a population-based study from a developing country. Hepatology 2012, 55:584-593.
13. de Ledinghen V., Vergniol J. Transient elastography (FibroScan). Gastroenterol. Clin. Biol. 2008, 32:58-67.
14. Eng J. Sample size estimation: how many individuals should be studied?. Radiology 2003, 227:309-313.
15. Eng M.Y., et al. ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature review. Alcohol Res. Health 2007, 30:22-27.
16. Foucher J., et al. Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study. Gut 2006, 55:403-408.
17. Ganne-Carrie N., et al. Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases. Hepatology 2006, 44:1511-1517.
18. Gekle M., et al. Transforming growth factor-b1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells. J. Physiol. 2003, 552:471-481.
19. Grove J., et al. Polymorphism associated with low interleukin-10 production is a risk factor for associated alcoholic liver disease. Gut 2000, 46:540-545.
20. Halsted C.H. Nutrition and alcoholic liver disease. Semin. Liver Dis. 2004, 2:3.
21. Hill D.B., et al. Mechanisms of Hepatic Injury in Alcoholic Liver Disease 1998, 703-721. Saunders, Philadelphia. A.J. McCullough, N. Gitlin (Eds.).
22. Kantartzis K., et al. Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. Diabetes 2009, 58:2616-2623.
23. Kebir O., et al. Association of inflammation genes with alcohol dependence/abuse: a systematic review and a meta-analysis. Eur. Addict. Res. 2011, 17:146-153.
24. Khan A.J., et al. Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis. Mutat. Res. 2009, 664:55-63.
25. Kotronen A., et al. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. Diabetologia 2009, 52:1056-1060.
26. Kotronen A., et al. Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors. Gastroenterology 2009, 137:865-872.
27. Ligers A., et al. CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms. Genes Immun. 2001, 2:145-152.
28. Machado M.V., et al. Does the simultaneous tumor necrosis factor receptor 2, tumor necrosis factor promoter gene polymorphism represent a higher risk for alcoholic liver disease?. Eur. J. Gastroenterol. Hepatol. 2009, 21:201-205.
29. Mandayam S., et al. Epidemiology of alcoholic liver disease. Semin. Liver Dis. 2004, 24:217-232.
30. Marcos M., et al. Interleukin-10 gene polymorphism is associated with alcoholism but not with alcoholic liver disease. Alcohol Alcohol. 2008, 43:523-528.
31. Marcos M., et al. Tumor necrosis factor polymorphisms and alcoholic liver disease: a HuGE review and meta-analysis. Am. J. Epidemiol. 2009, 170:948-956.
32. Mezey E. Alcoholic liver disease: roles of alcohol and malnutrition. Am. J. Clin. Nutr. 1980, 33:2709-2718.
33. Miller S.A., et al. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988, 16:1215.
34. Nahon P., et al. Assessment of liver fibrosis using transient elastography in patients with alcoholic liver disease. J. Hepatol. 2008, 49:1062-1068.
35. Neuman M.G. Cytokines-central factors in alcoholic liver disease. Alcohol Res. Health 2003, 27:307-316.
36. O'Shea R.S., et al. Alcoholic liver disease. Am. J. Gastroenterol. 2010, 105:14-32.
37. Oliver J., et al. Polymorphisms in the transforming growth factor-beta gene (TGFbeta) and the risk of advanced alcoholic liver disease. Liver Int. 2005, 25:935-939.
38. Pastor I., et al. Interleukin-1 gene cluster polymorphisms and alcoholism in Spanish men. Alcohol Alcohol. 2005, 40:181-186.
39. Purohit V., et al. Role of fatty liver, dietary fatty acid supplements, and obesity in the progression of alcoholic liver disease: introduction and summary of the symposium. Alcohol 2004, 34:3-8.
40. Ramadori G., Christ B. Cytokines and the hepatic acute phase response. Semin. Liver Dis. 1999, 19:141-155.
41. Rao V.R., et al. Single nucleotide polymorphisms in alcohol dehydrogenase genes among some Indian populations. Am. J. Hum. Biol. 2007, 19:338-344.
42. Romeo S., et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat. Genet. 2008, 40:1461-1465.
43. Romeo S., et al. Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. Int. J. Obes. (Lond) 2010, 34:190-194.
44. Schuppan D., Afdhal N.H. Liver cirrhosis. Lancet 2008, 371:838-851.
45. Sharma H.K., et al. The evolution of alcohol use in India. AIDS Behav. 2010, 14:S8-S17.
46. Sookoian S., et al. A nonsynonymous gene variant in adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J. Lipid Res. 2009, 50:2111-2116.
47. Stickel F., Sterreicher C. The role of genetic polymorphisms in alcoholic liver disease. Alcohol Alcohol. 2006, 41:209-224.
48. Stickel F., et al. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians. Hepatology 2010, 53:86-95.
49. Takamatsu M., et al. Genetic polymorphisms of interleukin 1beta in association with the development of alcoholic liver disease in Japanese patients. Am. J. Gastroenterol. 2000, 95:1305-1311.
50. Tilg H., Diehl A.M. Cytokines in alcoholic and nonalcoholic steatohepatitis. N. Engl. J. Med. 2000, 343:1467-1476.
51. UNICEF Monitoring progress toward the goals of the World Food Summit for Children: a practical handbook for multiple indicator surveys 1995, New York.
52. Verma V.K., et al. Extent and pattern of alcohol use and alcohol related problems in North India. Indian J. Psychiatry 1980, 22:331-337.
53. WHO International Guide for Monitoring Alcohol Consumption and Related Harm 2000, World Health Organization, Geneva.
54. WHO The World Health Report 2002-Reducing Risks, Promoting Healthy Life 2002, World Health Organization, Geneva.
55. WHO Current Information on Use and Harm from Alcohol in the South East Asia Region. WHO Global InfoBase (IB Ref: 101711c2) 2007.
56. Wilson A.G., et al. An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA A1, B8 and DR3 alleles. J. Exp. Med. 1993, 177:557-560.
57. Ziol M., et al. Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005, 41:48-54.