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Volumn 49, Issue 1, 2017, Pages 152-156

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

(22)  Lo, Min Tzu a   Hinds, David A b   Tung, Joyce Y b   Franz, Carol c   Fan, Chun Chieh a,d   Wang, Yunpeng e,f,g   Smeland, Olav B f,g   Schork, Andrew a,d   Holland, Dominic e   Kauppi, Karolina a,h   Sanyal, Nilotpal a   Escott Price, Valentina i   Smith, Daniel J j   O'Donovan, Michael i   Stefansson, Hreinn k   Bjornsdottir, Gyda k   Thorgeirsson, Thorgeir E k   Stefansson, Kari k   McEvoy, Linda K a   Dale, Anders M a,c,e   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANOREXIA NERVOSA; ANXIETY DISORDER; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BIPOLAR DISORDER; CHADL GENE; CHROMOSOME 8P; CHROMOSOME VARIANT; DEPRESSION; EXTRAVERSION; GBE1 GENE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC CORRELATION; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMAN; HUMAN GENOME; INTROVERSION; L3MBTL2 GENE; LINC00461 GENE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MENTAL DISEASE; MOLECULAR PATHOLOGY; MTMR9 GENE; NEUROSIS; PCDH15 GENE; PERSONALITY; PERSONALITY ASSESSMENT; PRIORITY JOURNAL; RBFOX1 GENE; SCHIZOPHRENIA; TRANSCRIPTION INITIATION SITE; WSCD2 GENE; XKR6 GENE; FEMALE; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; MALE; META ANALYSIS (TOPIC); MIDDLE AGED; PROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 85002374791     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3736     Document Type: Article
Times cited : (265)

References (68)
  • 1
    • 84934829884 scopus 로고    scopus 로고
    • Heritability of personality: A meta-analysis of behavior genetic studies
    • Vukasović , T. & Bratko, D. Heritability of personality: a meta-analysis of behavior genetic studies. Psychol. Bull. 141, 769-785 (2015).
    • (2015) Psychol. Bull. , vol.141 , pp. 769-785
    • Vukasović, T.1    Bratko, D.2
  • 2
    • 84964388798 scopus 로고    scopus 로고
    • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
    • Okbay, A. et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat. Genet. 48, 624-633 (2016).
    • (2016) Nat. Genet. , vol.48 , pp. 624-633
    • Okbay, A.1
  • 3
    • 84963502477 scopus 로고    scopus 로고
    • Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci
    • Smith, D.J. et al. Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci. Mol. Psychiatry 21, 749-757 (2016).
    • (2016) Mol. Psychiatry , vol.21 , pp. 749-757
    • Smith, D.J.1
  • 4
    • 0027348286 scopus 로고
    • The structure of phenotypic personality traits
    • Goldberg, L.R. The structure of phenotypic personality traits. Am. Psychol. 48, 26-34 (1993).
    • (1993) Am. Psychol. , vol.48 , pp. 26-34
    • Goldberg, L.R.1
  • 5
    • 84888027758 scopus 로고    scopus 로고
    • Dimensional models of personality: The five-factor model and the DSM-5
    • Trull, T.J. & Widiger, T.A. Dimensional models of personality: the five-factor model and the DSM-5. Dialogues Clin. Neurosci. 15, 135-146 (2013).
    • (2013) Dialogues Clin. Neurosci. , vol.15 , pp. 135-146
    • Trull, T.J.1    Widiger, T.A.2
  • 6
    • 84857356586 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies for personality
    • de Moor, M.H. et al. Meta-analysis of genome-wide association studies for personality. Mol. Psychiatry 17, 337-349 (2012).
    • (2012) Mol. Psychiatry , vol.17 , pp. 337-349
    • De Moor, M.H.1
  • 7
    • 84937399367 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder
    • de Moor, M.H. et al. Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder. JAMA Psychiatry 72, 642-650 (2015).
    • (2015) JAMA Psychiatry , vol.72 , pp. 642-650
    • De Moor, M.H.1
  • 8
    • 84887473103 scopus 로고    scopus 로고
    • Genome-wide association study of the five-factor model of personality in young Korean women
    • Kim, H.N. et al. Genome-wide association study of the five-factor model of personality in young Korean women. J. Hum. Genet. 58, 667-674 (2013).
    • (2013) J. Hum. Genet. , vol.58 , pp. 667-674
    • Kim, H.N.1
  • 9
    • 84923946495 scopus 로고    scopus 로고
    • LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
    • Bulik-Sullivan, B.K. et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat. Genet. 47, 291-295 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 291-295
    • Bulik-Sullivan, B.K.1
  • 10
    • 67349208210 scopus 로고    scopus 로고
    • Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: Implications for schizophrenia, autism and cancer
    • Tabarés-Seisdedos, R. & Rubenstein, J.L.R. Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer. Mol. Psychiatry 14, 563-589 (2009).
    • (2009) Mol. Psychiatry , vol.14 , pp. 563-589
    • Tabarés-Seisdedos, R.1    Rubenstein, J.L.R.2
  • 11
    • 84864285673 scopus 로고    scopus 로고
    • Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel loci
    • Bipolar Genome Study
    • Greenwood, T.A., Akiskal, H.S. & Akiskal, K.K. Bipolar Genome Study & Kelsoe, J.R. Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel loci. Biol. Psychiatry 72, 303-310 (2012).
    • (2012) Biol. Psychiatry , vol.72 , pp. 303-310
    • Greenwood, T.A.1    Akiskal, H.S.2    Akiskal, K.K.3    Kelsoe, J.R.4
  • 12
    • 11844305917 scopus 로고    scopus 로고
    • Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease
    • Green, E. et al. Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease. Am. J. Psychiatry 162, 35-42 (2005).
    • (2005) Am. J. Psychiatry , vol.162 , pp. 35-42
    • Green, E.1
  • 13
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421-427 (2014).
    • (2014) Nature , vol.511 , pp. 421-427
  • 14
    • 0034898198 scopus 로고    scopus 로고
    • Neuroticism as a risk factor for schizophrenia
    • Van Os, J. & Jones, P.B. Neuroticism as a risk factor for schizophrenia. Psychol. Med. 31, 1129-1134 (2001).
    • (2001) Psychol. Med. , vol.31 , pp. 1129-1134
    • Van Os, J.1    Jones, P.B.2
  • 15
    • 73549122994 scopus 로고    scopus 로고
    • Genome-wide association study of movement-related adverse antipsychotic effects
    • Åberg, K. et al. Genome-wide association study of movement-related adverse antipsychotic effects. Biol. Psychiatry 67, 279-282 (2010).
    • (2010) Biol. Psychiatry , vol.67 , pp. 279-282
    • Åberg, K.1
  • 16
    • 84907285601 scopus 로고    scopus 로고
    • Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
    • Rietveld, C.A. et al. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proc. Natl. Acad. Sci. USA 111, 13790-13794 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 13790-13794
    • Rietveld, C.A.1
  • 17
    • 84900494895 scopus 로고    scopus 로고
    • A meta-analysis of adult-rated child personality and academic performance in primary education
    • Poropat, A.E. A meta-analysis of adult-rated child personality and academic performance in primary education. Br. J. Educ. Psychol. 84, 239-252 (2014).
    • (2014) Br. J. Educ. Psychol. , vol.84 , pp. 239-252
    • Poropat, A.E.1
  • 18
    • 84901631426 scopus 로고    scopus 로고
    • Bayesian test for colocalisation between pairs of genetic association studies using summary statistics
    • Giambartolomei, C. et al. Bayesian test for colocalisation between pairs of genetic association studies using summary statistics. PLoS Genet. 10, e1004383 (2014).
    • (2014) PLoS Genet. , vol.10
    • Giambartolomei, C.1
  • 19
    • 84990996880 scopus 로고    scopus 로고
    • Heritability estimates of the Big Five personality traits based on common genetic variants
    • Power, R.A. & Pluess, M. Heritability estimates of the Big Five personality traits based on common genetic variants. Transl. Psychiatry 5, e604 (2015).
    • (2015) Transl. Psychiatry , vol.5 , pp. e604
    • Power, R.A.1    Pluess, M.2
  • 20
    • 80055014295 scopus 로고    scopus 로고
    • Personality and bipolar disorder: Dissecting state and trait associations between mood and personality
    • Barnett, J.H. et al. Personality and bipolar disorder: dissecting state and trait associations between mood and personality. Psychol. Med. 41, 1593-1604 (2011).
    • (2011) Psychol. Med. , vol.41 , pp. 1593-1604
    • Barnett, J.H.1
  • 21
    • 85047696382 scopus 로고    scopus 로고
    • A population-based twin study of the relationship between neuroticism and internalizing disorders
    • Hettema, J.M., Neale, M.C., Myers, J.M., Prescott, C.A. & Kendler, K.S. A population-based twin study of the relationship between neuroticism and internalizing disorders. Am. J. Psychiatry 163, 857-864 (2006).
    • (2006) Am. J. Psychiatry , vol.163 , pp. 857-864
    • Hettema, J.M.1    Neale, M.C.2    Myers, J.M.3    Prescott, C.A.4    Kendler, K.S.5
  • 22
    • 30344470812 scopus 로고    scopus 로고
    • The dark triad and normal personality traits
    • Jakobwitz, S. & Egan, V. The dark triad and normal personality traits. Pers. Individ. Dif. 40, 331-339 (2006).
    • (2006) Pers. Individ. Dif. , vol.40 , pp. 331-339
    • Jakobwitz, S.1    Egan, V.2
  • 23
    • 77952427364 scopus 로고    scopus 로고
    • The genetic and environmental relationship between major depression and the five-factor model of personality
    • Kendler, K.S. & Myers, J. The genetic and environmental relationship between major depression and the five-factor model of personality. Psychol. Med. 40, 801-806 (2010).
    • (2010) Psychol. Med. , vol.40 , pp. 801-806
    • Kendler, K.S.1    Myers, J.2
  • 24
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • Insel, T. et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am. J. Psychiatry 167, 748-751 (2010).
    • (2010) Am. J. Psychiatry , vol.167 , pp. 748-751
    • Insel, T.1
  • 25
    • 84888081456 scopus 로고    scopus 로고
    • The neuromodulator of exploration: A unifying theory of the role of dopamine in personality
    • DeYoung, C.G. The neuromodulator of exploration: a unifying theory of the role of dopamine in personality. Front. Hum. Neurosci. 7, 762 (2013).
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 762
    • DeYoung, C.G.1
  • 26
    • 84933054270 scopus 로고    scopus 로고
    • Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
    • Power, R.A. et al. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nat. Neurosci. 18, 953-955 (2015).
    • (2015) Nat. Neurosci. , vol.18 , pp. 953-955
    • Power, R.A.1
  • 27
    • 84907007552 scopus 로고    scopus 로고
    • Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: Toward biologically based nosologic criteria
    • Karalunas, S.L. et al. Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: toward biologically based nosologic criteria. JAMA Psychiatry 71, 1015-1024 (2014).
    • (2014) JAMA Psychiatry , vol.71 , pp. 1015-1024
    • Karalunas, S.L.1
  • 28
    • 0014831766 scopus 로고
    • The psychophysiological basis of introversion-extraversion
    • Gray, J.A. The psychophysiological basis of introversion-extraversion. Behav. Res. Ther. 8, 249-266 (1970).
    • (1970) Behav. Res. Ther. , vol.8 , pp. 249-266
    • Gray, J.A.1
  • 29
    • 84923060372 scopus 로고    scopus 로고
    • Five-factor model and internalizing and externalizing syndromes: A 5-year prospective study
    • Mezquita, L. et al. Five-factor model and internalizing and externalizing syndromes: a 5-year prospective study. Pers. Individ. Dif. 79, 98-103 (2015).
    • (2015) Pers. Individ. Dif. , vol.79 , pp. 98-103
    • Mezquita, L.1
  • 30
    • 70450223891 scopus 로고    scopus 로고
    • Common disorders are quantitative traits
    • Plomin, R., Haworth, C.M. & Davis, O.S. Common disorders are quantitative traits. Nat. Rev. Genet. 10, 872-878 (2009).
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 872-878
    • Plomin, R.1    Haworth, C.M.2    Davis, O.S.3
  • 31
    • 84957582620 scopus 로고    scopus 로고
    • GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person
    • Hu, Y. et al. GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person. Nat. Commun. 7, 10448 (2016).
    • (2016) Nat. Commun. , vol.7 , pp. 10448
    • Hu, Y.1
  • 32
    • 84968649781 scopus 로고    scopus 로고
    • Detection and interpretation of shared genetic influences on 42 human traits
    • Pickrell, J.K. et al. Detection and interpretation of shared genetic influences on 42 human traits. Nat. Genet. 48, 709-717 (2016).
    • (2016) Nat. Genet. , vol.48 , pp. 709-717
    • Pickrell, J.K.1
  • 33
    • 0041817568 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
    • Falush, D., Stephens, M. & Pritchard, J.K. Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164, 1567-1587 (2003).
    • (2003) Genetics , vol.164 , pp. 1567-1587
    • Falush, D.1    Stephens, M.2    Pritchard, J.K.3
  • 34
    • 84859224334 scopus 로고    scopus 로고
    • Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples
    • Henn, B.M. et al. Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. PLoS One 7, e34267 (2012).
    • (2012) PLoS One , vol.7
    • Henn, B.M.1
  • 35
    • 84957952518 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies for extraversion: Findings from the Genetics of Personality Consortium
    • van den Berg, S.M. et al. Meta-analysis of genome-wide association studies for extraversion: findings from the Genetics of Personality Consortium. Behav. Genet. 46, 170-182 (2016).
    • (2016) Behav. Genet. , vol.46 , pp. 170-182
    • Van Den Berg, S.M.1
  • 36
    • 84903820211 scopus 로고    scopus 로고
    • Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of Item Response Theory
    • van den Berg, S.M. et al. Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behav. Genet. 44, 295-313 (2014).
    • (2014) Behav. Genet. , vol.44 , pp. 295-313
    • Van Den Berg, S.M.1
  • 38
    • 84888202444 scopus 로고    scopus 로고
    • Psychometric properties of the Icelandic NEO-FFI in a general population sample compared to a sample recruited for a study on the genetics of addiction
    • Bjornsdottir, G. et al. Psychometric properties of the Icelandic NEO-FFI in a general population sample compared to a sample recruited for a study on the genetics of addiction. Pers. Individ. Dif. 58, 71-75 (2014).
    • (2014) Pers. Individ. Dif. , vol.58 , pp. 71-75
    • Bjornsdottir, G.1
  • 41
    • 58549119949 scopus 로고    scopus 로고
    • Ten facet scales for the Big Five Inventory: Convergence with NEO PI-R facets, self-peer agreement, and discriminant validity
    • Soto, C.J. & John, O.P. Ten facet scales for the Big Five Inventory: convergence with NEO PI-R facets, self-peer agreement, and discriminant validity. J. Res. Pers. 43, 84-90 (2009).
    • (2009) J. Res. Pers. , vol.43 , pp. 84-90
    • Soto, C.J.1    John, O.P.2
  • 43
    • 84983096378 scopus 로고    scopus 로고
    • LocusZoom: Regional visualization of genome-wide association scan results
    • Pruim, R.J. et al. LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics 26, 2336-2337 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2336-2337
    • Pruim, R.J.1
  • 44
    • 84874319780 scopus 로고    scopus 로고
    • Linear regression in genetic association studies
    • Bužková, P. Linear regression in genetic association studies. PLoS One 8, e56976 (2013).
    • (2013) PLoS One , vol.8
    • Bužková, P.1
  • 46
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium. et al.
    • 1000 Genomes Project Consortium. et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010).
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 47
    • 35348817330 scopus 로고    scopus 로고
    • Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
    • Browning, S.R. & Browning, B.L. Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am J. Human Genet. 81, 1084-1097 (2007).
    • (2007) Am J. Human Genet. , vol.81 , pp. 1084-1097
    • Browning, S.R.1    Browning, B.L.2
  • 48
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. & Abecasis, G.R. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44, 955-959 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 49
    • 84929132687 scopus 로고    scopus 로고
    • Large-scale whole-genome sequencing of the Icelandic population
    • Gudbjartsson, D.F. et al. Large-scale whole-genome sequencing of the Icelandic population. Nat. Genet. 47, 435-444 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 435-444
    • Gudbjartsson, D.F.1
  • 50
    • 84953239702 scopus 로고    scopus 로고
    • An empirical Bayes mixture model for effect size distributions in genome-wide association studies
    • Thompson, W.K. et al. An empirical Bayes mixture model for effect size distributions in genome-wide association studies. PLoS Genet. 11, e1005717 (2015).
    • (2015) PLoS Genet. , vol.11
    • Thompson, W.K.1
  • 51
    • 84958730027 scopus 로고    scopus 로고
    • Leveraging genomic annotations and pleiotropic enrichment for improved replication rates in schizophrenia GWAS
    • Wang, Y. et al. leveraging genomic annotations and pleiotropic enrichment for improved replication rates in schizophrenia GWAS. PLoS Genet. 12, e1005803 (2016).
    • (2016) PLoS Genet. , vol.12
    • Wang, Y.1
  • 52
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 53
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin, B. & Roeder, K. Genomic control for association studies. Biometrics 55, 997-1004 (1999).
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 54
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • Willer, C.J., Li, Y. & Abecasis, G.R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 55
    • 84926395609 scopus 로고    scopus 로고
    • Common genetic variants influence human subcortical brain structures
    • Hibar, D.P. et al. Common genetic variants influence human subcortical brain structures. Nature 520, 224-229 (2015).
    • (2015) Nature , vol.520 , pp. 224-229
    • Hibar, D.P.1
  • 56
    • 80051807776 scopus 로고    scopus 로고
    • Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study
    • So, H.C., Li, M. & Sham, P.C. Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study. Genet. Epidemiol. 35, 447-456 (2011).
    • (2011) Genet. Epidemiol. , vol.35 , pp. 447-456
    • So, H.C.1    Li, M.2    Sham, P.C.3
  • 57
    • 84862832570 scopus 로고    scopus 로고
    • Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
    • Yang, J. et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat. Genet. 44, 369-375 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 369-375
    • Yang, J.1
  • 58
    • 85000692305 scopus 로고    scopus 로고
    • An atlas of genetic correlations across human diseases and traits
    • Bulik-Sullivan, B. et al. An atlas of genetic correlations across human diseases and traits. Nat. Genet. 47, 1236-1241 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 1236-1241
    • Bulik-Sullivan, B.1
  • 59
    • 70450278666 scopus 로고    scopus 로고
    • The five-factor model of personality and borderline personality disorder: A genetic analysis of comorbidity
    • Distel, M.A. et al. The five-factor model of personality and borderline personality disorder: a genetic analysis of comorbidity. Biol. Psychiatry 66, 1131-1138 (2009).
    • (2009) Biol. Psychiatry , vol.66 , pp. 1131-1138
    • Distel, M.A.1
  • 60
    • 0034576243 scopus 로고    scopus 로고
    • Genetic structure of the five-factor model of personality in a Japanese twin population
    • Ono, Y. et al. Genetic structure of the five-factor model of personality in a Japanese twin population. Keio J. Med. 49, 152-158 (2000).
    • (2000) Keio J. Med. , vol.49 , pp. 152-158
    • Ono, Y.1
  • 61
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381, 1371-1379 (2013).
    • (2013) Lancet , vol.381 , pp. 1371-1379
  • 62
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat. Genet. 43, 977-983 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 977-983
  • 63
    • 84879892380 scopus 로고    scopus 로고
    • A mega-analysis of genome-wide association studies for major depressive disorder
    • Ripke, S. et al. A mega-analysis of genome-wide association studies for major depressive disorder. Mol. Psychiatry 18, 497-511 (2013).
    • (2013) Mol. Psychiatry , vol.18 , pp. 497-511
    • Ripke, S.1
  • 64
    • 84905856652 scopus 로고    scopus 로고
    • A genome-wide association study of anorexia nervosa
    • Boraska, V. et al. A genome-wide association study of anorexia nervosa. Mol. Psychiatry 19, 1085-1094 (2014).
    • (2014) Mol. Psychiatry , vol.19 , pp. 1085-1094
    • Boraska, V.1
  • 65
    • 84921750431 scopus 로고    scopus 로고
    • Genetic variability in the regulation of gene expression in ten regions of the human brain
    • Ramasamy, A. et al. Genetic variability in the regulation of gene expression in ten regions of the human brain. Nat. Neurosci. 17, 1418-1428 (2014).
    • (2014) Nat. Neurosci. , vol.17 , pp. 1418-1428
    • Ramasamy, A.1
  • 66
    • 80053572217 scopus 로고    scopus 로고
    • Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies
    • Trabzuni, D. et al. Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies. J. Neurochem. 119, 275-282 (2011).
    • (2011) J. Neurochem. , vol.119 , pp. 275-282
    • Trabzuni, D.1
  • 67
    • 84959158225 scopus 로고    scopus 로고
    • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept
    • Franke, B. et al. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat. Neurosci. 19, 420-431 (2016).
    • (2016) Nat. Neurosci. , vol.19 , pp. 420-431
    • Franke, B.1
  • 68
    • 84903957329 scopus 로고    scopus 로고
    • SECA: SNP effect concordance analysis using genome-wide association summary results
    • Nyholt, D.R. SECA: SNP effect concordance analysis using genome-wide association summary results. Bioinformatics 30, 2086-2088 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 2086-2088
    • Nyholt, D.R.1


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