Chemical study, antioxidant, anti-hypertensive, and cytotoxic/cytoprotective activities of Centaurea cyanus L. petals aqueous extract

Food and Chemical Toxicology

Volumn 118, Issue , 2018, Pages 439-453

  Escher, Graziela Bragueto ^a   Santos, Jânio Sousa ^a   Rosso, Neiva Deliberali ^a   Marques, Mariza Boscacci ^a   Azevedo, Luciana ^b   do Carmo, Mariana Araújo Vieira ^b   Daguer, Heitor ^c   Molognoni, Luciano ^c   Prado Silva, Leonardo do ^d   Sant'Ana, Anderson S ^d   da Silva, Marcia Cristina ^e   Granato, Daniel ^a  

^a STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^b FEDERAL UNIVERSITY OF ALFENAS   (Brazil)

^c Livestock and Food Supply (MAPA)   (Brazil)

^d UNIVERSITY OF CAMPINAS   (Brazil)

^e Federal Institute of Education   (Brazil)

Author keywords

Desirability function; Flavonoids; LC ESI MS MS; Phenolic compounds; Protocyanins; Response surface methodology

Indexed keywords

4 AMINOBENZOIC ACID; APIGENIN; BENZOIC ACID; BETA RESORCYLIC ACID; CAFFEIC ACID; CATECHIN; CENTAUREA CYANUS EXTRACT; CHLOROGENIC ACID; CONIFERALDEHYDE; COUMARIN; EPICATECHIN; FERULIC ACID; GALANGIN; GALLIC ACID; GENTISIC ACID; HESPERIDIN; HYMECROMONE; ISOQUERCITRIN; KAEMPFEROL; LUTEOLIN; PARA COUMARIC ACID; PINOCEMBRINE; PLANT EXTRACT; PROTOCATECHUIC ACID; SALICYLIC ACID; SINAPALDEHYDE; SYRINGALDEHYDE; SYRINGIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANILLIC ACID; ANTHOCYANIN; ANTIHYPERTENSIVE AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; COUMARIC ACID; COUMARIN DERIVATIVE; QUERCETIN; WATER;

ANALYSIS OF VARIANCE; ANTIHYPERTENSIVE ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL STRAIN; CELL PROTECTION; CENTAUREA; CENTAUREA CYANUS; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOTOXICITY; ELECTROSPRAY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC50; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; PHYTOCHEMISTRY; PROCESS OPTIMIZATION; RESPONSE SURFACE METHOD; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; FLOWER; HEMOLYSIS; LIQUID CHROMATOGRAPHY; MICROBIAL SENSITIVITY TEST; PH; PRECLINICAL STUDY; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE;

ANTHOCYANINS; ANTIHYPERTENSIVE AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; CAFFEIC ACIDS; CELL LINE, TUMOR; CENTAUREA; CHLOROGENIC ACID; CHROMATOGRAPHY, LIQUID; COUMARIC ACIDS; COUMARINS; DRUG EVALUATION, PRECLINICAL; FLOWERS; HEMOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; LIPID PEROXIDATION; MICROBIAL SENSITIVITY TESTS; PLANT EXTRACTS; QUERCETIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; WATER;

EID: 85047461374     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2018.05.046     Document Type: Article

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